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Journal : Medula

Literature Review: Faktor-Faktor Penyebab Kejadian Rehospitalisasi Pada Pasien Congestive Heart Failure (CHF) Kylalona, Gracylia; Suri, Nurma; Aulia Ramdini, Dwi; Sukohar, Asep
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.1039

Abstract

Congestive Heart Failure (CHF) is a health disorder with a poor prognosis due to functional or structural heart defects that interfere with ventricular filling or blood ejection into the systemic circulation. CHF remains a significant global health concern with high rates of morbidity and mortality. The number of diagnosed CHF leading to frequent rehospitalization or re-admission due to symptom recurrence. Patients who experience readmitted to the hospital after initial admission have a risk of mortality, with about 50% dying within 6 months and 25-35% passing away within 12. In this review focuses on exploring the factors contributing to rehospitalization among CHF patients. The methodolgy involved analyzing electronic database for relevant studies published over the past decade. Factors identified as leading to rehospitalization in CHF patients include a history of hypertension, non-compliance with taking medication, and an unhealthy lifestyle. Pharmacists play an important role in providing education to patients and helping to fulfill patient medication compliance.
Profil Penggunaan Antibiotik Pada Pasien Infeksi Saluran Pernapasan Akut (ISPA) Balita di Beberapa Pelayanan Kesehatan Salsabilla, Kharisma; Nurmasuri, Nurmasuri; Wardhana, Muhammad Fitra
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1082

Abstract

Acute Respiratory Infection (ARI) is a disease caused by the transmission of pathogens that infect the respiratory tract and result in disruption of normal respiratory activities in individuals. The cause of ARI itself can come from a viral or bacterial infection. Therapy for ARI caused by bacteria can use antibiotics. Giving antibiotics for ARI depends on the bacteria causing it. The principles of using antibiotic therapy are empirical therapy and definitive therapy. This literature study aims to determine the percentage of antibiotic use and the choice of antibiotics most frequently given to ARI patients. This research uses a literature review method with a search for articles using Google Scholar, Science Direct and Pubmed published in 2018-2024. Journals are collected using journal websites from searches using relevant keywords. After that, they are assessed regarding eligibility according to relevant researchers' criteria and a relevant review is carried out. The results of the review show that the use of antibiotics as ARI therapy often occurs, the use of antibiotics being the most frequently used in ARI such as amoxicillin and cephalosporin which have the same function and effectiveness. Antibiotics for clinical symptoms should be given based on clear indications, antibiotic administration should be based on the results of microbiological examination. This literature review can be used to evaluate the appropriateness of using antibiotics as an effort to prevent resistance.
Review Artikel: Aktivitas Farmakologi Daun Alpukat (Persea americana Mill.) Rahmadhita, Elmira; Iqbal, Muhammad; Oktoba, Zulpakor; Nurmasuri, Nurmasuri; Triyandi, Ramadhan
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1174

Abstract

Indonesia possesses abundant natural resources, including the abundant fish, which are considered an alternative to modern diets. Fish, particularly alpaca, have high economic value and potential for local consumption. Alpaca is rich in protein, selenium, minerals, and anti-inflammatory properties that can help maintain health and prevent kidney damage.Alpukat (Persea america Mill.) is a rich, commercially valuable, and potentially beneficial food source for local consumption. Research has shown that alpaca can help prevent kidney damage by providing essential nutrients like potassium, magnesium, vitamin E, flavonoid, saponin, alkaloid, steroid, vitamin E, mineral, natrium, tanin, alkaloida, quersetin, polifenol, asam lemak tidak jenuh, zat filantik, and kalium. Alpukat also contains flavonoid and quersetin, which help prevent cholesterol accumulation and reduce the risk of lipid oxidation. Flavonoid and quersetin also help prevent glucosa absorption and oxidative stress, which can lead to cancer and other health issues. Alpukat also contains potassium with diuretic effects, which can be used for treating ginkgo biloba, kencing biloba, tinggi, and sakit kepala. Diuretik, a substance that increases urine volume and excretion of waste, can help prevent kidney damage. In conclusion, Indonesia has a rich and diverse food supply, including various types of fish, which have significant economic and health benefits.
POTENSI INTERAKSI OBAT PADA PASIEN SKIZOFRENIA Suri, Nurma; Salsabila, Lyansaputri; Adjeng, Andi Nafisah Tendri; Oktafany, Oktafany
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1165

Abstract

In the treatment of schizophrenia, antipsychotics as the main therapy are generally combined with additional therapy. Combination therapy has a risk of drug interactions. The aim of the study was to describe the potential factors that influence drug interactions. The study was conducted using observational quantitative analytic methods with a retrospective cross-sectional approach. The sample was selected by total sampling method in the medical records of inpatients at the Lampung Mental Hospital from January-December 2022. The Lexicomp software was used to identify potential drug interactions. In the 265 samples, 344 treatment profiles were obtained with a total of 1349 drugs used. Then, 1786 potential drug interactions were classified as level of risk A (0%), B (0.8%), C (80.2%), D (19%), and X (0%). There was a significant relationship between gender, length of stay, and number of drugs (p<0.05) on potential drug interaction level D (major). Multivariate analysis showed the number of drugs had the strongest relationship (p=0.000 OR=8.233) to potential drug interactions. There was a significant relationship between gender, length of stay, and number of drugs with potential drug interactions level D. The number of drugs had the strongest with potential drug interactions.
Co-Authors Afriyana, Regi Afriyani, Afriyani Al Rasyid, Muhammad Irfan Ambarwati, Endah Antika Sintia, Nova Asep Sukohar Asep Sukohar Asti, Windi Athallah, Muhammad Muzhafar Atri Sri Ulandari Aufa Nurrohmah, Anna Aulia Ramdini, Dwi Axcellia Theresa Ayu SWP, Fadillah Cathartica, Allamanda Cheri F. A. Dera Chintia Dwi Tanasa Ciptaningrum, Sekar Rahmasari Ratna Citra Yuliyanda Pardilawati Damayanti, Ervina Dedy Miswar Devvy Wahyu Mulyaningsih Diva Meylia Dwi Melani Dwi, Farah Farhana, Lubna Farras Qanitah Rony Febriana, Triana Ihsanti Dwi Rahayu Junando, Mirza Kirana, Shela Sandra Kylalona, Gracylia Lilik Koernia Wahidah Mallarangeng, Andi Nafisah Tendri Adjeng Mega Intan Yulianti Mirza Junando Muhammad Fitra Wardhana Sayoeti Muhammad Iqbal Muhammad Maulana Nawawi, As’ari Niken Dwi Astarina Oktafany Oktafany Oktafany, Oktafany Oktarlina, Resmi Zakiah Oktoba, Zulpakor Pardilawati, Citra Yuliyanda Pius Ave Rafael Silalahi Prabamukti, Ilyas Primadiamanti, Annisa Putri, Oka Mahila Gustia Rahmadhita, Elmira Rahman, M. Bobby Ramadhina, Farrasyifa Ramdini, Dwi Aulia Rasmi Zakiah Oktarlina Ratih Anggun Komalasari Rizki Nisfi Ramdhini Rony, Farras Qanitah Roviq Umam S Salsabila, Lyansaputri Salsabilla, Kharisma Saputri, Gusti Ayu Rai Sarnianto, Prih Suryadi Islami Syahputri, Devina Harti Triyandi, Ramadhan Vanadis, Zifa Aisha Wardhana, Muhammad Fitra Widodo, Alya Rahmah Widodo, Subur Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Wirasutisna, Komar Ruslan Yati Sumiyati, Yati Yuli Wahyu Tri Mulyani Yulianti, Mega Intan