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PERBANDINGAN TEKNIK MASSAGE EFFLEURAGE (MENGGOSOK) DENGAN TEKNIK MASSAGE SHAKING (GONCANGAN) PADA SEGMEN TUNGKAI BAWAH TERHADAP PENURUNAN KADAR ASAM LAKTAT SETELAH LATIHAN FISIK ANAEROBIK Abdul Syafei; Hardi Darmawan; Theodorus
Jurnal Kesehatan : Jurnal Ilmiah Multi Sciences Vol 7 No 12 (2017): JURNAL KESEHATAN: JURNAL ILMIAH MULTI SCIENCIES
Publisher : STIK SITI KHADIJAH PALEMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52395/jkjims.v7i12.200

Abstract

Aktivitas fisik dengan intensitas tinggi dapat menyebabkan terjadinya peningkatan kadar asam laktatdalam darah maupun otot. Peningkatan kadar asam laktat, merupakan salah satu faktor penyebabterjadinya kelelahan. Untuk mengurangi kelelahan dilakukan dengan massage yang merupakanmanipulasi sederhana dengan mengusap tubuh yang sakit pada struktur jaringan lunak yang dapatmenenangkan serta mengurangi stress psikologis. Tujuan penelitian adalah untukmengetahui perbandingan teknik massage effleurage dengan teknik massage shaking terhadappenurunan kadar asam laktat setelah aktivitas fisik anaerobik. Penelitian uji klinik berpembandingdalam bentuk open lable dengan rancangan pretest-postest design. Subjek penelitian mahasiswa FKIPjurusan pendidikan olahraga universitas sriwijaya palembang berjumlah 51 responden yang memenuhikriteria inklusi, dibagi menjadi tiga kelompok yaitu kelompok teknik massage effleurage, kelompokteknik massage shaking, dan kelompok kontrol yang masing-masing kelompok berjumlah 17responden. Pada masing-masing kelompok dilakukan pemeriksaan laktat awal (pre test), kemudiansetelah aktivitas 5 menit dilakukan pemeriksaan kadar asam laktat (post test), dan dilakukanmassage pada kelompok perlakuan sedangkan kelompok kontrol tidak dilakukan massage. setelah 20menit dilakuan pemeriksaan kadar asam laktat (post massage). Hasil uji statistik menunjukkan nilairerata kadar asam laktat sebelum aktivitas pada kelompok teknik massage effluarage (menggosok)yaitu 3,406±0,96 sedangkan sesudah aktivitas yaitu 8,959±1,24. Rerata kadar asam laktat sebelumaktivitas pada kelompok teknik massage shaking (goncangan) yaitu 3,241±0,78 sedangkan sesudahaktivitas yaitu 8,276±0,77. Rerata kadar asam laktat sebelum aktivitas pada kelompok kontrol yaitu3,406±0,96 sedangkan sesudah aktivitas yaitu 8,959±1,24. Sedangkan pada kelompok setelahperlakuan teknik massage effluarage (menggosok) didapat nilai yaitu 3,800±1,07 dan pada teknikmassage shaking (goncangan) didapat nilai yaitu 4,065±0,56 hal ini menunjukkan bahwa tidak adaperbedaan bermakna antara teknik massage effluarage (menggosok) dengan teknik massage shaking(goncangan) dengan p value 0,416 (p>0,05). Dapat disimpulkan bahwa massage effleurage danmassage shaking sama-sama dapat menurunkan kadar asam laktat setelah aktivitas fisik anaerobik.
DIAGNOSTIC TEST OF POSTERIOR SEGMENT OCULAR EXAMINATION ON THE SEVERITY OF PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) AT DR. MOHAMMAD HOESIN GENERAL HOSPITAL PALEMBANG Putra, Chani Sinaro; Amin, Ramzi; Sari, Dian Puspita; Theodorus
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/axmc2035

Abstract

Background: Acute lymphoblastic leukemia (ALL) is one of the highest incidence of all cancers in children. Ocular involvement can diagnose the development of the disease. Patients with ALL often have ocular manifestations either resulting from direct infiltration or indirect causes of neoplastic cells. The aim of this study to diagnose from posterior segment findings on disease severity in pediatric patients with acute lymphoblastic leukemia (ALL) at Muhammad Hoesin Hospital Palembang Methods: A diagnostic test to determine the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of posterior segment findings in disease severity diagnostic of pediatric patients with ALL from November 2021 to May 2022. Posterior segment findings that were evaluated included retinal hemorrhages, roth spots, exudate and papilledema. Disease severity of pediatric ALL is divided into high risk and standard risk. All data were analyzed using SPPS version 22.0 Results: There were 68 patients who selected by inclusion criteria. A total of 30 (44.1%) subjects with high risk and 38 (55.9%) with standard risk. in this study there is no patient have papilledema and only one patient (1.5%) has retinal hemorrhage, roth spot and exudate. From statistical analysis, it was found that the three posterior findings had a sensitivity of 0% and a specificity of 97.4%. Conclusion: The results of this study show that the findings of the posterior eye segment can be used as a screening tool for the severity of acute lymphoblastic leukemia, because only one component of sensitivity and specificity has a value of > 80%.
Predicting Burn Patient Mortality: A Comparative Analysis of the BOBI and R-Baux Scoring Systems Abda Arif; Ruli Robi Ferli; Theodorus
Sriwijaya Journal of Surgery Vol. 8 No. 1 (2025): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v8i1.116

Abstract

Introduction: Burns represents a significant global health challenge, causing considerable morbidity and mortality. Accurate prognostication is crucial for optimal burn care management. This study compared the accuracy of the BOBI and R-Baux scores in predicting mortality among burn patients. Methods: This retrospective study analyzed data from 46 burn patients treated at Dr. Mohammad Hoesin General Hospital Palembang. Patient demographics, burn characteristics, and mortality outcomes were recorded. BOBI and R-Baux scores were calculated for each patient. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and Youden Index were determined for both scores. Agreement between the scores was assessed using the Kappa statistic. Statistical analysis was performed using SPSS v25. Results: The majority of patients were male (76.1%) and under 50 years old (84.8%). Fire burns (63%) and superficial-mid dermal injuries (32.6%) were most prevalent. The BOBI score demonstrated fair accuracy (sensitivity: 84.6%, specificity: 63.6%, PPV: 0.478, NPV: 0.913, Youden Index: 0.480). The R-Baux score showed lower sensitivity (76.9%) but higher specificity (78.8%) (PPV: 0.588, NPV: 0.896, Youden Index: 0.560). The Kappa test indicated good agreement between the two scores (κ = 0.783, p = 0.000). Conclusion: Both BOBI and R-Baux scores can be used to predict mortality in burn patients. The BOBI score demonstrated higher sensitivity, while the R-Baux score exhibited higher specificity. The choice of scoring system may depend on the specific clinical context and the relative importance of sensitivity and specificity.
Predicting Conversion to Open Cholecystectomy: A Validation Study of the Difficult Laparoscopic Cholecystectomy Scoring System Muhammad Hafidh Komar; Imanuddin, Kiagus Ahmad; Theodorus
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 12 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i12.1137

Abstract

Background: Laparoscopic cholecystectomy (LC) has become the gold standard for managing symptomatic gallstone disease. However, a subset of patients requires conversion to open cholecystectomy (OC) due to intraoperative difficulties. The difficult laparoscopic cholecystectomy scoring system (DLCSS) has been proposed to predict the likelihood of conversion. This study aimed to validate the DLCSS in a single-center setting and assess its predictive accuracy for conversion to OC. Methods: A retrospective analysis was conducted on patients who underwent LC at Dr. Mohammad Hoesin General Hospital Palembang, Indonesia, between January and December 2023. Preoperative, intraoperative, and postoperative data were collected. The DLCSS was calculated for each patient, and its correlation with conversion to OC was analyzed using statistical methods. Results: A total of 30 patients were included in the study. The conversion rate to OC was 3.3%. Statistical analysis revealed a weak negative correlation between the DLCSS and conversion to OC (r = -0.318, p = 0.087), suggesting that higher DLCSS scores were associated with a slightly increased likelihood of conversion, although this association was not statistically significant. Conclusion: The DLCSS demonstrated limited predictive value for conversion to OC in our single-center study. Further research with larger sample sizes and diverse patient populations is needed to confirm the utility of the DLCSS in predicting conversion and to identify additional factors that may contribute to intraoperative difficulties during LC.
EFFECTIVENESS OF ANTHOCYANIN AS A HEPATOPROTECTOR: A SYSTEMATIC LITERATURE REVIEW Amanda Putri, Khairunnisa Rizqika; Lusiana, Evi; Theodorus; Rosdah, Ayeshah Augusta; Harahap, Debby Handayati; Larasati, Veny
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 12 No. 1 (2025): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v12i1.453

Abstract

Exposure to free radicals can cause hepatotoxicity in liver cells. Hepatoprotectors are needed to prevent free radicals. The flavonoid group anthocyanin compounds, which give many plants purple, blue, and red colors, have antioxidant activity as hepatoprotectors. This study uses a systematic literature review to review the effectiveness of various plants containing anthocyanins as hepatoprotectors. Articles were searched using Google Scholar, PubMed, and NCBI with keywords such as "Anthocyanin compounds and Hepatoprotective effects" that met the inclusion and exclusion criteria. The results obtained from 7 review articles show that several plants contain anthocyanins, such as bilberry and blackberry, Rosella, purple cabbage, butterfly pea flower, Aronia melanocarpa Elliot (AMA), red cabbage, and radish. The mechanisms in plants containing anthocyanins as hepatoprotective include antioxidant activity, inhibition of cytochrome enzymes, inhibition of inflammation, protein expression, and modulation of the apoptotic signal pathway. This review concludes that plants containing anthocyanins are effective as natural hepatoprotectors with various mechanisms.
Can Pediatric Appendicitis Risk Calculator Replace Pediatric Appendicitis Score? A Comparative Study in Diagnosing Acute Appendicitis in Children Egha; Windi Astriana; Theodorus
Sriwijaya Journal of Surgery Vol. 8 No. 1 (2025): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v8i1.119

Abstract

Introduction: Acute appendicitis is the most common cause of operative emergencies in children, necessitating prompt and accurate diagnosis to minimize complications. Clinical scoring systems like the pediatric appendicitis score (PAS) and the more recent pediatric appendicitis risk calculator (pARC) have been developed to aid in diagnosis. This study aimed to compare the accuracy of pARC and PAS in diagnosing acute appendicitis in children. Methods: This retrospective study analyzed the medical records of pediatric patients (age: 5-18 years) admitted to Dr. Mohammad Hoesin General Hospital Palembang with suspected acute appendicitis between October 2022 and October 2024. pARC and PAS scores were calculated for each patient, and their diagnostic accuracy was compared using histopathology results as the gold standard. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and kappa statistics were calculated. Results: A total of 36 patients with histopathologically confirmed acute appendicitis were included. The pARC score demonstrated a sensitivity of 82.8%, specificity of 100%, PPV of 96.6%, and NPV of 100%. The PAS score showed a sensitivity of 80.0%, specificity of 100%, PPV of 96.5%, and NPV of 100%. The kappa statistic indicated good agreement between pARC and PAS (0.861). Conclusion: Both pARC and PAS demonstrated high accuracy in diagnosing acute appendicitis in children. While pARC showed slightly higher sensitivity and PPV, the difference was not statistically significant. These findings suggest that pARC could potentially replace PAS as the preferred diagnostic tool, but further research with larger sample sizes is needed to confirm these results.
Chemotherapy and Quality of Life in Breast Cancer Patients: A Case-Series Study in Palembang, Indonesia Eka Satyani Belina; Mulawan Umar; Theodorus
Sriwijaya Journal of Surgery Vol. 8 No. 1 (2025): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v8i1.120

Abstract

Introduction: Breast cancer is a prevalent malignancy affecting women worldwide, and its treatment, particularly chemotherapy, can significantly impact patients' quality of life (QoL). This study aimed to assess the QoL of breast cancer patients undergoing chemotherapy in Palembang, Indonesia, and to identify factors associated with their QoL. Methods: A cross-sectional study was conducted at the Oncology Unit of Dr. Mohammad Hoesin General Hospital in Palembang, Indonesia, from December 2024 to January 2025. A total of 150 breast cancer patients who met the inclusion criteria were enrolled in the study. Data were collected through medical records and the Functional Assessment of Cancer Therapy - Breast (FACT-B) questionnaire. The FACT-B assesses QoL in five domains: physical, social/family, emotional, functional, and breast cancer-specific concerns. Descriptive statistics, Spearman's correlation, and logistic regression were used to analyze the data. Results: The majority of the patients were aged 40-60 years (70%), had low educational levels (41.3%), were married (83.3%), had locally advanced disease (44%), and had completed chemotherapy (41.3%). The mean FACT-B total score was 76.8. A significant negative correlation was found between the intensity of chemotherapy and QoL (r = -0.306, p = 0.000). Logistic regression analysis revealed that patients who had completed chemotherapy had a significantly lower QoL than those who had not undergone chemotherapy (OR = 0.30, 95% CI = 0.15-0.60, p = 0.001). Conclusion: Chemotherapy significantly impacts the QoL of breast cancer patients in Palembang, Indonesia. Patients who have completed chemotherapy have a lower QoL than those who have not undergone chemotherapy. These findings highlight the importance of providing comprehensive supportive care to breast cancer patients undergoing chemotherapy to improve their QoL.
The use of cetirizine in allergic contact dermatitis patients at Sekip Palembang Health Center Rukmana, Cici Chintya Aulia; Harahap, Debby Handayati; Theodorus
Indonesian Journal of Pharmacology and Therapy Vol 6 No 1 (2025)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.12729

Abstract

World Allergy Organization (WAO) reported that 22% of the global population experiences allergies, and this prevalence continues to increase each year. The prevalence of dermatitis in Indonesia is quite high, at 6.78%, with the highest rate in South Kalimantan (11.3%) and the lowest in West Sulawesi (2.57%). In South Sumatra, approximately 2,584,000 people suffer from dermatitis. Therapy for allergic contact dermatitis patients includes medicamentous treatments, such as systemic antihistamines, with cetirizine being one of the options. This study aimed to determine the pattern of cetirizine use, including the frequency, duration of administration, and the characteristics of allergic contact dermatitis patients such as gender and age who received cetirizine therapy. The drug utilization study of cetirizine was conducted in December 2021 at the Sekip Palembang Community Health Center, involving 34 out of 49 patients who met the inclusion criteria. The sampling method used was total sampling. The majority of allergic contact dermatitis patients were late elderly individuals, aged 56-65 yr (32.4%), and women (58.8%). Rationality assessment showed good results in terms of diagnosis (100%), indication (100%), duration of drug administration (97.1%), frequency of drug administration (100%), and drug interactions (93.7%). This study hopefully can enhance the effectiveness of cetirizine usage, enabling healthcare providers to prescribe the medication more rationally according to the patients' allergic symptoms.
Eliminating HPV DNA Positive Result with Large Loop Excision of the Transformation Zone (LLETZ)/Loop Electrosurgical Excision Procedure (LEEP) in Precancerous Cervical Lesions Sanif, Rizal; Agustiansyah, Patiyus; Nurwany, Raissa; Sastradinata, Irawan; Theodorus; Agustian, Wisman
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 2 April 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i2.1897

Abstract

Abstract Objective: To determine the use of LLETZ/LEEP to eliminate HPV DNA positive result in patients with cervical precancerous lesions at General Hospital dr. Mohammad. Hoesin, Palembang. Methods: A case series with cervical precancerous lesions was undertaken at the Oncology Polyclinic of dr.Mohammad Hoesin Hospital Palembang from January to October 2022. There were 24 samples with positive HPV DNA before LLETZ/LEEP. Samples then checked for HPV DNA after LLETZ/LEEP. The effectiveness of LLETZ/LEEP therapy was analyzed using the Mc Nemar test. Comparison of HPV DNA outcomes (positive or negative) based on procedure, HPV DNA type and histopathological type was analyzed using Fisher Exact and Pearson Chi Square tests. All data were analyzed using SPPS version 22.0. Results: In this study, it was found that the average age of patients with cervical precancerous lesions was 40.25 ± 7.67 years (28 - 57 years). Based on the diagnosis, 8 samples were found with High-grade Squamous Intraepithelial Lesion (HGSIL) and 16 samples with Low-grade Squamous Intraepithelial Lesion (LGSIL). All samples in this study were housewives and the majority were multiparas (75.0%). History of abortion in the patients in this study was only found in 5 samples (20.8%). The results showed that there were significant differences in the HPV DNA before and after LLETZ/LEEP therapy (p = 0.000). In addition, the results showed that there was no difference in the outcome of HPV DNA based on the procedure (p = 1.000) and the type of HPV DNA (p = 0.643). After LLETZ/LEEP therapy was carried out, it was found that only 1 subject has positive HPV DNA result and the HPV DNA virus found was type 52 and (high risk) and 42 (low risk). Conclusion: It can be concluded that LLETZ/LEEP therapy is effective in eliminating HPV DNA positive results in cervical precancerous lesions Keywords: cervical cancer, HPV DNA, LLETZ/LEEP, precancerous lesions, RCT
Predicting Mortality in Gastric Perforation: A Comparative Analysis of Boey Score and Mannheim Peritonitis Index Accuracy in an Indonesian Tertiary Hospital Bobi Wijaya; Alsen Arlan; Theodorus
Sriwijaya Journal of Surgery Vol. 8 No. 1 (2025): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v8i1.124

Abstract

Introduction: Peptic ulcer perforation (PUP), often leading to gastric perforation, represents a significant surgical emergency demanding rapid intervention. Effective risk stratification using prognostic scoring systems is crucial for optimizing patient management and improving outcomes. This study aimed to evaluate and compare the predictive performance of the Mannheim Peritonitis Index (MPI) and the Boey Score in estimating in-hospital mortality risk among patients presenting with gastric perforation at a tertiary hospital in Indonesia. Methods: A retrospective descriptive study employing an accuracy testing design was conducted. Data were collected from the medical records of 31 adult patients (≥18 years) who underwent exploratory laparotomy for non-traumatic gastric perforation at Dr. Mohammad Hoesin General Hospital Palembang, between January 2023 and December 2024. Patients with incomplete medical records were excluded. Boey Scores and MPI scores were calculated for each patient based on predefined criteria. The primary outcome measured was in-hospital mortality. Statistical analysis included descriptive statistics, calculation of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and Receiver Operating Characteristic (ROC)1 curve analysis to determine optimal cutoff values. Results: The median age was 62 years, with a male predominance (87.1%). Most patients presented late (>24 hours post-perforation, 90.3%) and had organ dysfunction (80.6%). Preoperative shock was present in 48.4%. The optimal cutoff for MPI predicting mortality was ≥22, yielding a sensitivity of 87.5% and specificity of 40.0%. The optimal Boey Score cutoff was ≥2, with a sensitivity of 75.0% and specificity of 53.3%. Comparing MPI (cutoff ≥22) against Boey Score (cutoff ≥2) as a reference, the MPI demonstrated an accuracy of 74.19%, sensitivity of 73.91%, specificity of 75.00%, PPV of 89.47%, and NPV of 50.00%. Conclusion: Both the Boey Score and MPI showed moderate predictive performance for in-hospital mortality in patients with gastric perforation in this cohort. MPI (cutoff ≥22) demonstrated higher sensitivity for identifying high-risk patients compared to the Boey Score (cutoff ≥2), although with lower specificity regarding mortality itself. MPI appears advantageous for identifying high-risk individuals, while the simpler Boey Score remains useful for rapid initial assessment.