Article Per Year (5 Year)
p-Index From 2020 - 2025
4.885
P-Index
This Author published in this journals
All Journal Jurnal Ilmiah Farmasi International Journal of Biosciences and Biotechnology Jurnal Farmasi Udayana Majalah Obat Tradisional Farmasains : Jurnal Ilmiah Ilmu Kefarmasian WIDYABHAKTI Jurnal Ilmiah Populer Jurnal Ilmu Kefarmasian Indonesia Jurnal Karinov Jurnal Aplikasi dan Inovasi Iptek (JASINTEK) Jurnal Ilmiah Medicamento Usadha Medical Sains : Jurnal Ilmiah Kefarmasian
Erna Cahyaningsih
Universitas Mahasaraswati Denpasar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

Published : 48 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 48 Documents
Search

 1   2   3   4   5 
Kajian Etnofarmasi Kelompok Masyarakat Banjar Subamia Kelong, Tabanan Bali Perayanthi, Reni; Anita Dewi, Ni Luh Kade Arman; Kusuma Yuda, Putu Era Sandhi; Cahyaningsih, Erna; Vernandes Sasadara, Maria Malida; Suradnyana, I Gede Made; Sugiyanto, Milyadi
Usadha Vol 3 No 2 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i2.7369

Abstract

  Bali is rich in culture and traditions passed down from generation to generation, especially in the ethnopharmacy aspect as a traditional medecine. This research aims to study ethnopharmacy aspects of the application of herbal plants as traditional medicine including plant parts, processing methods, indications, and usage of herbal plants in Banjar Subamia Kelong, Tabanan, Bali. This research was carried out using survey methods, direct observation in the field, and interviews. This research identified 20 types of plants that are generally used by the community in the Banjar Subamia Kelong. The plant parts generally used are leaves (60%), stems (15%), rhizomes (15%) and fruit (10%). Most of the plants are processed by boiling (60%). These medicinal plants are mostly used orally (65%), and the general indication is to treat joint problems, such as muscle pain and gout (25%).
UJI EFEK ANALGESIK INFUSA DAUN KAYU PUTIH (Melaleuca trichostachya Lindl.) PADA MENCIT JANTAN (Mus musculus L.) Cahyaningsih, Erna; Suwarni, Elis
Jurnal Ilmiah Medicamento Vol 3 No 1 (2017): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v3i1.1038

Abstract

Tanaman kayu putih (Melaleuca trichostachya Lindl.) dari familia Myrtaceae termasuk dalam tumbuhan obat yang sudah dimanfaatkan untuk pengobatan tradisional di Indonesia salah satunya sebagai analgesik. Beberapa senyawa yang terkandung dalam kayu putih yang diduga bersifat analgesik antara lain terpineol. Tujuan dari penelitian ini untuk mengetahui adanya efek analgesik dari infusa daun kayu putih (Melaleuca trichostachya Lindl.) pada mencit jantan (Mus musculus L.). Penelitian ini ialah penelitian eksperimental dengan menggunakan metode rangsang panas pada suhu 55oC. Pada penelitian ini digunakan hewan uji berupa mencit jantan yang dibagi dalam lima kelompok masing-masing terdiri dari 5 ekor mencit. Kelompok kontrol positif diberi asetosal 1,3mg/20g BB, kelompok kontrol negatif diberi aquadest 2,5ml/100g BB, kelompok uji diberi infusa daun kayu putih konsentrasi 5%, 10% dan 20% masing-masing 2,5ml/100g BB. Pengamatan dilakukan setelah 15 menit pemberian sampel ketika mencit diletakkan di atas hot plate. Data yang diperoleh selanjutnya dianalisis dengan metode statistik (ANOVA). Hasil penelitian menunjukkan bahwa terjadi peningkatan waktu munculnya respon mencit (pertama kali menjilat kakinya), pada kelompok yang diberi infusa daun kayu putih. Berdasarkan hasil dapat disimpulkan bahwa infusa daun kayu putih memiliki efek analgesik pada mencit jantan.
Karagenan Rumput Laut Merah Bali (Gracilaria sp.) sebagai Antibakteri terhadap Delapan Bakteri Patogen Sasadara, Maria Malida Vernandes; Cahyaningsih, Erna; Dewi, Ni Luh Kade Arman Anita; Yuda, Putu Era Sandhi Kusuma; Wardani, I Gusti Agung Ayu Kusuma; Juliadi, Debby; Putri, Ni Kadek Dila Pratiwi; Putri, Ni Kadek Nisa Leoni; Darmawan, I Wayan Agus; Yanti, Ni Kadek Pradnya
Jurnal Ilmiah Medicamento Vol 11 No 1 (2025): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i1.10349

Abstract

The increase in infection cases every year, coupled with the rise in resistance cases, increases the urgency of exploring antimicrobial agents. Gracilaria sp. is a red seaweed that is widely known as one of the potential producers of active metabolites, sulfated polysaccharides. Carrageenan is one form of sulfated polysaccharide that has antimicrobial activity. This study was conducted to evaluate the antibacterial activity of carrageenan derived from Gracilaria sp. against several pathogenic bacteria, including Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterococcus faecalis, Streptococcus pyogenes, and Salmonella typhi. Carrageenan was extracted from Gracilaria sp. samples obtained from the South Denpasar area (Bali) using KOH. An antibacterial activity assay of carrageenan was carried out using an agar well diffusion method with nutrient agar media. Tests were conducted at concentrations of 1 and 5 mg/mL (E. coli and S. epidermidis), 20, 30, 40 mg/mL (S. aureus, S. pyrogenes, E. faecalis, and S. typhi), 50, 75, and 100 mg/mL (P. aeruginosa and K. pneumoniae). Incubation was carried out for 24 hours at ± 37 °C. Data were analyzed statistically by one-way ANOVA and Kruskal-Wallis with a 95% confidence level. The results showed that carrageenan extracted from Gracilaria sp. exhibited significant antibacterial activity against several pathogenic bacteria, especially gram-negative bacteria. The antibacterial activity produced in this study was proportional to the increase in concentration, where the inhibitory activity produced increased as the concentration of carrageenan increased. It can be concluded that carrageenan has the potential to be an antibacterial.
Identifikasi Senyawa Fitokimia dan Uji Aktivitas Antioksidan pada Cascara (Coffea arabica L.) Sasadara, Maria Malida Vernandes; Cahyaningsih, Erna; Yuda, Putu Era Sandhi Kusuma; Handani, Dewa Ayu Sri; Dewi, Ni Luh Kade Arman Anita; Megawati, Fitria; Tirtayasa, Gede Agus Ari
Usadha Vol 4 No 1 (2025): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v4i1.12181

Abstract

Cascara refers to the dried husk of coffee cherries. It has garnered significant attention in recent research due to its phytochemical composition and potential health benefits. Several studies have highlighted the presence of bioactive compounds and the antioxidant activity exhibited by cascara. This study aims to investigate the phytochemical content and antioxidant potential of cascara. The cascara was extracted using the maceration method with 96% ethanol, followed by phytochemical screening for alkaloids, flavonoids, tannins, saponins, terpenoids, steroids, and quinones using standard color reactions in test tubes. Antioxidant activity was assessed via the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay, with ascorbic acid as a reference compound. The phytochemical profile of the extract was identified using gas chromatography-mass spectrometry (GC-MS). The findings indicated that cascara contains alkaloids, flavonoids, tannins, saponins, and triterpenoids. GC-MS analysis identified caffeine, hexadecanoic acid (methyl ester), and hexadecanoic acid (ethyl ester) as the predominant compounds in cascara. The antioxidant activity test using the DPPH method demonstrated that the ethanol extract of cascara possesses moderate antioxidant potential, with an average IC50 value of 108.49 ± 1.28 ppm. Ascorbic acid, the reference compound used in this study, yielded an IC50 of 2.53 ppm, categorized as very strong. This research underscores cascara’s potential as a valuable source of antioxidants with significant health benefits, influenced by geographic factors affecting its bioactive compound profile. Consequently, cascara holds promise for further development as a raw material for functional health-promoting products.
PHYTOCHEMICAL PROFILING OF PURNAJIWA FRUIT (Kopsia arborea Blume.) EXTRACTS AND ANTIBACTERIAL ACTIVITY AGAINST METHICILLIN-RESISTANT Staphylococcus aureus (MRSA) Sasadara, Maria Malida Vernandes; Cahyaningsih, Erna; Yuda, Putu Era Sandhi Kusuma; Apriliani, Ni Luh Putri; Dewi, Ni Kadek Dwi Purnama; Ni Luh Kade Arman Anita Dewi
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 3 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i3.1767

Abstract

Purnajiwa (Kopsia arborea Blume.) contains diverse phytochemicals with notable antibacterial potential. This study aimed to characterize and quantify the phytochemicals of Kopsia arborea fruit extracts obtained by maceration and Soxhlet extraction with methanol and evaluate their antibacterial activity against MRSA through phytochemical screening, GC-MS analysis, spectrophotometric quantification of flavonoids, alkaloids, and phenolics, and disc diffusion assay at 100 ?g/mL concentration. The findings indicated that the Soxhlet extraction produced a superior yield (19.47 ± 0.58%) compared to maceration (11.09 ± 0.65%). Phytochemical analysis revealed the presence of alkaloids, flavonoids, phenolics, tannins, saponins, and triterpenoids, with no qualitative differences between the two extracts. Quantitative analysis demonstrated higher concentrations of alkaloids, flavonoids, and phenolics in the Soxhlet extract, with values of 88.58 ± 3.76, 46.50 ± 1.04, and 57.87 ± 0.44 ?g/mL, respectively, compared to the maceration extract (50.46 ± 3.86, 26.22 ± 0.27, and 30.49 ± 0.31 ?g/mL, respectively). GC-MS analysis identified 13 alkaloid compounds in the Soxhlet extract and 12 in the maceration extract. Antibacterial assays revealed that the mean inhibition zone diameter against MRSA was 11.69 ± 0.28 mm for the Soxhlet extract and 12.61 ± 0.27 mm for the maceration extract, respectively. In conclusion, Soxhlet extraction yielded higher concentrations of alkaloids, phenolic compounds, and flavonoids; however, GC-MS analysis revealed that the macerated extract exhibited a higher AUC of alkaloid compounds than that of Soxhlet extraction. Moreover, the macerated extract demonstrated superior antibacterial activity, indicating that maceration has greater potential for development as an antibacterial agent than Soxhlet extraction.
Review: Pemanfaatan Tanaman sebagai Fitoterapi pada Diabetes Mellitus Dewi, Ni Luh Kade Arman Anita; Prameswari, Putu Nimas Diyah; Cahyaningsih, Erna; Megawati, Fitria; Agustini, Ni Putu Dewi; Juliadi, Debby
Usadha Vol 1 No 3 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v1i3.5562

Abstract

Diabetes is a chronic disease that occurs due to high levels of sugar in the blood, this can occur when the pancreas does not produce enough insulin (a hormone that regulates blood sugar or glucose), or when the body cannot effectively use the insulin it produces. Management of DM patients can be carried out with non-pharmacological and pharmacological therapies. The method used in the journal review was to search for the keyword "diabetes mellitus herbal medicine" for clinical studies on plant-derived products for the treatment of diabetes mellitus. Search terms included “phytotherapy”, “phytochemicals”, “medicinal plant products”, “herbal medicine”, and “diabetes mellitus”. Involving plant-derived compounds and pigmentation as outcome measures were included. In this review article, 30 journals were collected from which the objectives and results of the research in the journal were obtained. The goal is as an alternative management treatment to control blood sugar levels. For some of the compounds we discuss, among others: Flavonoids, Allicin, Lectins, Alkaloids, Andrographolid, Curcumin, Cinnamaldehyde, peptides, Phenolics, Tannins.
Efektivitas Pengobatan Tanaman Herbal dan Terapi Tradisional untuk Penyakit Tulang dan Persendian Cahyaningsih, Erna; Anita Dewi, Ni Luh Kade Arman; Udayani, Ni Nyoman Wahyu; Dwipayanti, Ni Kadek Sari; Megawati, Fitria
Usadha Vol 1 No 3 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v1i3.5596

Abstract

Bones are the body's framework that causes the body to stand upright, where the muscles are attached to allow the passage of blood vessels, where the bone marrow and nerves protect soft tissues. Traditional medicine is an effort to treat or treat other ways outside of medical science or nursing science. Indonesia is one of the countries that have the potential to develop medicinal plant cultivation and use it as an alternative treatment. This study aims to determine the effectiveness of herbal medicine and traditional therapy for bone and joint diseases. This study uses the method of literature study. The results showed that traditional herbal therapy for ball compresses, lemongrass warm compresses, cinnamon warm compresses, lavender aromatherapy warm water flower compresses, bangle rhizome compresses, and ginger warm compresses can be used for bone and joint diseases. Where there are compounds in herbal plants that have effectiveness as traditional medicine and therapy for bone and joint diseases, namely flavonoids, quercetin, curcumin, 6-gingerol and shogaol, alkaloids, steroids, and saponins.
Aktivitas Antibakteri Ekstrak Tanaman Obat terhadap Methicillin-Resistant Staphylococcus aureus (MRSA) Dwi Widyastrini, Desak Made; Cahyaningsih, Erna; I Gusti Agung Ayu Kusuma Wardani
Usadha Vol 1 No 1 (2021): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Meningkatnya kemunculan infeksi multidrug-resistant yang disebabkan oleh mikroorganisme telah menjadi beban yang signifikan secara global. Mereka telah menghasilkan tingkat kematian, kecacatan dan penyakit yang tinggi di seluruh dunia terutama di negara berkembang. Laporan dari Centre for Disease Control and Prevention (CDC) memperkirakan bahwa lebih dari 2 juta penyakit dan 23.000 kematian per tahun disebabkan oleh patogen resisten antibiotik di Amerika Serikat, salah satunya yaitu Methicillin-Resistant Staphylococcus aureus (MRSA). Tanaman obat telah diakui memiliki efek samping yang minimal dan juga dapat menekan pertumbuhan patogen dengan mekanisme yang berbeda dari antibiotik sintetik yang digunakan saat ini. Tujuan penulisan artikel review ini untuk mempelajari aktivitas antibakteri ekstrak tanaman obat terhadap Methicillin-Resistant Staphylococcus aureus (MRSA). Metode yang digunakan dalam penyusunan artikel review ini yaitu studi literatur melalaui beberapa basis data yang kemudian diskrining dengan beberapa kriteria. Hasil review mengatakan bahwa vankomisin sebelumnya merupakan obat yang digunakan secara luas untuk pengobatan infeksi MRSA. Hal ini tidak lagi terjadi dengan munculnya strain S. aureus dengan sensitivitas vankomisin yang berkurang sehingga membatasi pilihan pengobatan konvensional untuk infeksi MRSA. Saat ini, banyak peneliti telah melaporkan aktivitas antibakteri dari banyak ekstrak tanaman pada MRSA. Konsentrasi hambat minimum (MIC) dan konsentrasi bakterisida minimum (MBC) digunakan untuk menilai aktivitas antibakteri ekstrak dari tanaman obat. Berdasarkan hasil dapat disimpulkan bahwa tanaman obat dapat digunakan sebagai kandidat alternatif untuk pengembangan obat yang dapat menghentikan atau mengendalikan infeksi dari MRSA.
Co-Authors Agrippina Wiraningtyas, Agrippina Agustini, Ni Putu Dewi Anak Agung Putu Gede Bagus Arie Susandya Anita Dewi, Ni Luh Kade Arman Apriliani, Ni Luh Putri Artini, Ni Putu Eka Darmawan, I Wayan Agus Darmayanti, Gusti Ayu Putu Eka Debby Juliadi Dewi, Ni Kadek Dwi Purnama Dwi Arymbhi Sanjaya Dwi Widyastrini, Desak Made Dwipayanti, Ni Kadek Sari Elis Suwarni Fitria Megawati Gusti Ayu Made Indah Siantari Gusti Ayu Putu Eka Darmayanti Gusti Ayu Putu Yosinta Sasmita Handani, Dewa Ayu Sri I Made Agus Sunadi Putra I Putu Tangkas Suwantara I Putu Tangkas Suwantara Indah Muthia Susanthi Indriani, Felia Riska Irma Rubianti Kusuma Yuda, I Putu Era Sandhi Kusuma Yuda, Putu Era Sandhi Luh Risma Putri Rahayu Made Agus Deny Mahendra Putra Maria Daniela Tupa Hokor Maria Dewi, Ni Putu Maria Malida Vernandes Sasadara Megawati, Fitria Ni Luh Ayu Mega Ratnasari Ni Luh Kade Arman Anita Dewi Ni Luh Kade Arman Anita Dewi Ni Luh Sintya Ni Made Dharma Shantini Suena Ni Made Dwi Mara Widyani Nayaka Ni Made Wiwik Setiawati Ni Nyoman Wahyu Udayani Ni Putu Anggun Cipta Rosalita Jelantik Ni Putu Dewi Agustini Ni Putu Eka Artini Ni Putu Udayana Antari Ni Putu Yuni Winariyanthi Olahairullah, Olahairullah Perayanthi, Reni Pramesti , Luh Ratih Widhia Prameswari, Putu Nimas Diyah Puguh Santoso Puguh Santoso Puguh Santoso puguh santoso, puguh Puspita Wati, Ni Putu Putra Hilmi Prayitno Putra, I Made Agus Sunadi Putri, Leoni Putri, Ni Kadek Dila Pratiwi Putri, Ni Kadek Nisa Leoni Putu Eka Pasmidi Ariati Putu Era Sandhi K.Yuda Putu Era Sandhi Kusuma Yuda Sandhi Kusuma Yuda, Putu Era Sasadara, Maria Malida Vernandes Sugiyanto, Milyadi Suradnyana, I Gede Made Surya Rahadi, I Wayan Susanthi, Indah Muthia Suwantara, I Putu Tangkas Suwarni, Elis Tirtayasa, Gede Agus Ari Vernandes Sasadara, Maria Malida Wardani, I Gusti Agung Ayu Kusuma Widyani Nayaka , Ni Made Dwi Mara Wiguna, Putu Dony Saputra Winariyanthi, Ni Putu Yuni Yanti, Ni Kadek Pradnya