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All Journal Medula CESS (Journal of Computer Engineering, System and Science) Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Respirasi (JR) JK Unila (Jurnal Kedokteran Universitas Lampung) JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Setiawan, Gigih
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Hubungan Diabetes Melitus Terhadap Derajat Berat Penyakit Paru Obstruktif Kronis (PPOK) Di Klinik Harum Melati Pringsewu Provinsi Lampung Soemarwoto, Retno Ariza; Putri, Maharani; Esfandiari, Firhat; Triwahyuni, Tusy; Setiawan, Gigih
Jurnal Kedokteran Universitas Lampung Vol 3, No 1 (2019): JK Unila
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v3i1.2293

Abstract

Penyakit Paru Obstruksi Kronik (PPOK) merupakan penyakit kronik progresif yang ditandai dengan keterbatasan aliran udara di dalam saluran napas yang tidak sepenuhnya reversibel. Diabetes Melitus (DM) dapat menjadi faktor resiko yang mempengaruhi struktur dan fungsi paru. DM dikaitkan dengan peningkatan resiko infeksi paru, eksaserbasi penyakit dan memburuknya PPOK. Penelitian ini bertujuan untuk mengetahui adanya hubungan diabetes melitus terhadap derajat berat PPOK di Klinik Harum Melati Kabupaten Pringsewu Provinsi Lampung. Metode penelitian dilakukan secara analitik deskriptif dengan pendekatan cross sectional. Penelitian dilakukan di Klinik Harum Melati Kabupaten Pringsewu Provinsi Lampung pada bulan Maret 2016. Sampel pada penelitian ini diambil secara total sampling dari data rekam medik berdasarkan kriteria inklusi. Data dikumpulkan dan dilakukan uji analisis menggunakan uji Mann Whitney. Hasil penelitian didapatkan karakteristik responden kelompok terbanyak berdasarkan usia adalah 60 – 74 tahun (54,4 %) dan jenis kelamin laki – laki sebesar 85,4 %. Hasil penelitian dapat diketahui bahwa dari 70 responden yang tidak menderita penyakit DM, yang mederita PPOK derajat ringan yaitu 26 responden (25,2 %) dan dari 33 responden yang menderita penyakit DM, sebanyak 12 responden (11,7 %) menderita PPOK derajat berat. Hasil analisis bivariat menunjukan ada hubungan signifikan antara DM dengan derajat PPOK di klinik Harum Melati Kabupaten Pringsewu Provinsi Lampung ( p = 0,008). DM meningkatkan resiko komorbid dan peningkatan derajat berat PPOK. Diabetes melitus dengan kadar gula tidak terkontrol atau keadaan hiperglikemia dapat menyebabkan peningkatan derajat berat PPOK.Kata Kunci: Diabetes melitus, PPOK.
Uji Efektivitas Biolarvasida Pada Minyak Atsiri Daun Tembelekan (Lantana camara) Terhadap Larva Anopheles sp. Sebagai Upaya Pengendalian Vektor Malaria Marcellia, Selvi; Ramdini, Dwi Aulia; Setiawan, Gigih; Septiani, Linda; Setyaningrum, Endah; Rosa, Emantis; Annasya, Benazhir Saninah
Jurnal Ilmu Kedokteran dan Kesehatan Vol 11, No 12 (2024): Volume 11 Nomor 12
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v11i12.18425

Abstract

Indonesia merupakan salah satu negara dengan jumlah kasus malaria yang tertinggi di dunia. Penyakit malaria merupakan jenis penyakit yang penularannya melalui gigitan nyamuk Anopheles sp. yang mengandung protozoa Plasmodium sp. Daun lantana (Lantana camara L.) memiliki kandungan senyawa aktif lantadine, minyak atsiri, flavonoid, alkaloid, saponin, dan tannin. Penggunaan biolarvasida merupakan upaya untuk mengurangi preventif Penelitian ini bertujuan untuk mengetahui efektivitas minyak atsiri daun lantana sebagai biolarvasida terhadapvektor penyakit Malaria.Metode yang digunakan pada penelitian ini adalah destilasi untuk proses ekstraksi, dan menghitung jumlah kematian dari larva yang telah diberi perlakuan dengan konsentrasi minyak atsiri daun lantana 0,5%, 0,75%, 1%, 1,25% sehingga didapatkan nilai persen mortalitas dan dilanjutkan dengan menghitungan nilai LC50 dan LC90 menggunakan uji probit. Hasil penelitian menunjukkan bahwa minyak atsiri daun lantana (Lantana camara) efektif sebagai biolarvasida. LC50 yang di dapat yaitu0,505% pada jam ke-21. Untuk uji ANOVA menunjukkan terdapat perbedaan yang signifikan pada masing-masing konsentrasi 0,5%, 0,75%, 1%, 1,25%, control negative dan control positif karena nilai p-value 0,000<0,05. Dari hasil penelitian ini dapat dikatakan bahwa senyawa yang terkandung pada minyak atsiri daun lantana (Lantana camara) berpotensi sebagai biolarvasida terhadap larva Anopheles sp.
Faktor-Faktor yang Berpengaruh terhadap Kelelahan Kerja pada Petugas Pemadam Kebakaran : Tinjauan Pustaka Adhim, Muhammad Risqi; Mayasari, Diana; Setiawan, Gigih
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1319

Abstract

Occupational Safety and Health (K3) is an important aspect in protecting workers from the risk of work accidents, including work fatigue which can have an impact on physical and mental health. Workplace fatigue often occurs due to various factors that can cause physiological and psychological disorders. Firefighters are a profession that has a high risk of work fatigue, considering the high number of fire incidents and the response system which is still not optimal. Heavy workloads and high physical and mental demands further increase the risk of work fatigue in firefighters. This research uses a literature review method by analyzing various academic journals published in the last five years (2019–2024). The research results show that there are two main factors that influence work fatigue, namely internal factors and external factors. Internal factors include age, years of service, smoking status, and sleep patterns. Meanwhile, external factors include workload, work stress, work attitudes and working time. Untreated work fatigue can have a negative impact on the work safety and productivity of firefighters, and even increase the risk of work accidents. Therefore, preventive efforts and a thorough evaluation of work safety limits are needed to minimize the risk of fatigue and create a safer and healthier work environment for firefighters.
Pengaruh HbA1c Terhadap Profil Lipid pada Pasien Diabetes Melitus Tipe 2 Suci, Maghfirly Juniarti Eka; Tjiptaningrum, Agustyas; Setiawan, Gigih; Kurniati, Intanri
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1263

Abstract

Diabetes Mellitus (DM) is characterized by a state of hyperglycemia due to insulin resistance, decreased insulin production, or both of these conditions which are classified into metabolic diseases. When checking the condition of type 2 DM, HbA1c can be checked as an indicator. High and uncontrolled HbA1c levels will cause disturbances in lipid profiles such as increased triglycerides, LDL, total cholesterol, and decreased HDL. The purpose of this study is to determine whether or not there is an effect of HbA1c on lipid profiles in type 2 DM patients. This method uses scientific publication search media such as Google Scholar, Pubmed, and old medical scientific journals using the keywords “lipid profile, HbA1c, type 2 diabetes mellitus, and dyslipidemia” obtained 15,700 articles and scientific journals. In patients with type 2 diabetes mellitus, glycemic control can be determined by HbA1c examination, high HbA1c levels are associated with disruption of lipid profile levels. The results of the study discuss the effect of HbA1c levels on lipid profiles in patients with type 2 diabetes and determine the relationship between the two.
Relationship between Student Engagement in Learning and Grade Point Average of Students Kristiani, Rini; Oktafany; Setiawan, Gigih; Lisiswanti, Rika
Medula Vol 14 No 11 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i11.1353

Abstract

Student engagement in learning is a form of student participation in the learning process. There are three dimensions in student involvement, namely behavioral, emotional, and cognitive dimensions. This study aims to find the relationship between student engagement in learning and its dimensions on GPA in students of the Medical Education Study Program, Faculty of Medicine, Lampung University (PSPD FK Unila). This research design is descriptive analytic with a cross-sectional approach conducted on students of class 2022 PSPD FK Unila with the sampling technique is total sampling. The data collection process used the University Student Engagement Inventory (USEI) questionnaire along with demographic data for GPA. The research was conducted in October-November 2024. The analysis was conducted using the spearman test. The results showed that the level of student engagement The highest was in the medium + low category totaling 168 students (80.8%), the most dominant dimension in engagement was behavioral engagement, then cognitive, and the lowest was emotional. Most students' GPA is in the very satisfactory category (64.5%), followed by praise (20.2%), and the last is satisfactory (15.3%). There was a significant relationship between student engagement in learning and GPA (p value = 0.027, r = 0.155). Further analysis found that there was a relationship between behavioral engagement on GPA (p value = 0.014, r = 0.173) and cognitive engagement on GPA (p value = 0.021, r = 0.162), while emotional engagement showed no significant relationship on GPA (p value = 0.558). There is a significant relationship between student engagement in learning and GPA in FK Unila PSPD students. The dimensions that are significantly related to GPA are the dimensions of behavioral and cognitive engagement, while the emotional dimension does not show a significant relationship to student GPA.
Gambaran Budaya Keselamatan Pasien di Rumah Sakit: Tinjauan Pustaka Amallia, Rizka Dina; Pramesona, Bayu Anggileo; Setiawan, Gigih; Saftarina, Fitria
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1389

Abstract

Patient safety culture is the key to providing high-quality and safe healthcare services. All healthcare providers, especially nurses, must be committed to creating and maintaining a strong patient safety culture. This research aims to gain a deep understanding of patient safety culture. The method used is a literature study taken from PubMed and Google Scholar databases published within the last 5 years and relevant to the topic. The selected articles are those that are fully available, focus on hospitals as the research site, and are written in Indonesian or English. The research shows that a good patient safety culture, characterized by leadership support, teamwork, open communication, and an effective incident reporting system, can improve the quality of healthcare and reduce risk of medical errors. However, many hospitals have not fully implemented a patient safety culture optimally. Some common challenges include low incident reporting rates, lack of leadership support, and a lack of a learning culture from mistakes. To address this problem, continuous efforts are needed to build a strong patient safety culture, such as increasing staff awareness, providing training, and creating safe environment for reporting errors.
Aktivitas Antibakteri Epigallocatechin Gallate (EGCG) Teh Hijau pada Bakteri Gram Positif dan Bakteri Gram Negatif Afifah, Syafira Hasna; Apriliana, Ety; Setiawan, Gigih; Berawi, Khairun Nisa
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1446

Abstract

Epigallocatechin gallate (EGCG) is a catechin compound found in green tea and is known for its various health benefits, including antioxidant, anti-inflammatory, and antibacterial activity. Research on the antibacterial effects of EGCG shows that this compound has significant potential in inhibiting the growth of various pathogens, both Gram-positive and Gram-negative bacteria. Gram-positive bacteria, such as Staphylococcus aureus and Streptococcus pneumoniae, are more sensitive to EGCG than Gram-negative bacteria. The antibacterial mechanism of EGCG in Gram-positive bacteria involves disrupting cell membrane integrity and inhibiting biofilm formation, while in Gram-negative bacteria, EGCG can increase the permeability of the outer membrane and increase the penetration efficiency of antibiotics. However, the main challenge in using EGCG against Gram-negative bacteria is the structural barrier present in the outer membrane, which limits the penetration of the compound. The use of EGCG in combination therapy with antibiotics shows great potential in overcoming antibiotic-resistant infections, strengthening antibacterial activity, and reducing side effects. Although EGCG shows promise as an antibacterial therapy, challenges related to bioavailability, stability, and formulation need to be overcome to optimize its potential in the treatment of difficult-to-treat bacterial infections.
Pulmonary Aspergilloma Co-Existing with Pulmonary Tuberculosis: A Case Report in Type 1 Diabetes Mellitus (T1DM) Patient Kirana, Widya Tria; Faisal, Hana Khairina Putri; Kitagawa, Hiroki; Setiawan, Gigih; Yunus, Faisal
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.213-219

Abstract

Introduction: Pulmonary aspergilloma is a disease frequently found in immunocompromised patients. In Indonesia, around 18% of diabetes mellitus (DM) patients suffer from chronic pulmonary aspergilloma. However, data on type 1 DM (T1DM) are still limited. Case: We presented the case of a 22-year-old male admitted to the emergency room due to hemoptysis of approximately 200 ml within six hours before admission, nonspecific chest pain during cough, fever, night sweats, and weight loss of 3 kg over the last months. The patient had a history of T1DM and no prior history of respiratory diseases. Physical examination showed tachycardia, tachypnoea, subfebrile, normal body mass index, and rhonchi on the left thorax. Routine laboratory tests revealed increased blood sugar level (503 mg/dL) and HbA1c 16.4%. Chest X-ray and high-resolution computed tomography (HRCT) showed a cavity with an opaque lesion, crescent sign, consolidation, and reticulonodular infiltrate on the left lung. Rapid molecular tests, tuberculosis (TB), and serum galactomannan (GM) were negative. The patient was diagnosed with pulmonary aspergilloma, T1DM, and clinical TB. He was treated with fluconazole, insulin, and a fixed-dose combination of anti-TB. The patient refused the surgery procedure. Immediately, the hemoptysis stopped, blood glucose level was normal, and concomitant with weight gain. Conclusion: Due to innate and acquired immunity impairment, T1DM is a risk factor for pulmonary infections, including TB and pulmonary aspergilloma. Chest HRCT may help diagnose fungal balls. Though the patient refused to undergo surgery, administering antifungal, anti-TB drugs, and glucose control as initial treatment presented a good prognosis in the patient.
Rancang Bangun Sistem Pengambilan Salinan Putusan atau Penetapan Berbasis Website Guna Menunjang Pelayanan Pada Pengadilan Negeri Surakarta Kelas IA Khusus Setiawan, Gigih; Khusnuliawati, Hardika; Susilo, Dahlan
CESS (Journal of Computer Engineering, System and Science) Vol. 10 No. 2 (2025): Juli 2025
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/cess.v10i2.66646

Abstract

Pelayanan pengambilan salinan putusan atau penetapan di Pengadilan Negeri Surakarta Kelas IA Khusus sebelumnya dilakukan secara manual kerap menimbulkan berbagai kendala, seperti keterlambatan penyampaian informasi, kurangnya transparansi, serta potensi kesalahan administrasi. Untuk menyelesaikan masalah tersebut, dikembangkan sistem dalam bentuk aplikasi berbasis web bernama e-Silinder (Elektronik Sistem Pengambilan Salinan Putusan/Penetapan by Order). Tujuan penelitian ini untuk membangun sekaligus menerapkan digitalisasi sistem agar efisiensi, transparansi, dan akuntabilitas layanan dalam proses pengambilan salinan putusan/penetapan dapat meningkat. Metode waterfall, yang meliputi tahap analisis kebutuhan, perancangan/desain sistem, pengkodean, dan pengujian, digunakan dalam perancangan aplikasi e-Silinder. Penerapan sistem menunjukkan proses permohonan salinan dapat dilakukan secara mandiri oleh pemohon melalui perangkat digital, diverifikasi oleh petugas, dan kemudian diambil sesuai jadwal yang ditentukan. Sistem ini terbukti mendukung proses digitalisasi pelayanan serta berkontribusi terhadap peningkatan kualitas layanan di lingkungan peradilan.
Peningkatan Pengetahuan akan Bahaya Perokok Pasif sebagai Upaya Mencegah Terjadinya Infeksi Saluran Nafas Akut pada Balita di Desa Tegal Rejo, Kecamatan Gading Rejo, Kabupaten Pringsewu Setiawan, Gigih; Wahyudo, Riyan; Morfi, Chicy Widya; Fattima, Eliza Techa
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 2 No. 1 (2016): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v2i1.1161

Abstract

Target pencapaian poin ke-4 Millennium Development Goals (MDGs) mengurangi kematian anak salah satu poinnya adalah menurunkan angka kematian balita 2/3 dari tahun 1990-2015. Kematian balita umumnya disebabkan oleh penyakit infeksi. Dari penyakit infeksi tersebut 2/3 adalah infeksi saluran pernapasan akut. ISPA akan menyerang host apabila ketahanan tubuh menurun. Bayi di bawah lima tahun adalah kelompok yang memiliki sistem kekebalan tubuh yang masih rentan terhadap berbagai penyakit. Anak balita yang memiliki anggota keluarga dengan kebiasaan merokok berisiko 4,2 kali lebih tinggi untuk menderita ISPA dibandingkan dengan anak balita dengan anggota keluarga yang tidak merokok. Pemecahan masalah yang diterapkan pada kegiatan ini mencakup penyuluhan mengenai bahaya dari merokok. Penyuluhan juga lebih mendalami bagaimana hubungan merokok dengan kejadian infeksi saluran nafas akut bisa terjadi pada perokok pasif disekitar mereka terutama anak balita. Penyuluhan dilaksanakan pada tanggal 15 Maret 2015 di Desa Tegal Rejo, Kecamatan Gading Rejo, Kabupaten Pringsewu Kegiatan penyuluhan mengenai bahaya perokok pasif pada balita ini diikuti oleh 100 orang warga desa. Setelah mendapatkan penyuluhan tentang materi perokok pasif dan dampak yang ditimbulkan khususnya dalam upaya pencegahan infeksi saluran nafas pada anak balita, maka pengetahuan warga-warga di Desa Tegal Rejo, Kecamatan Gading Rejo, Kabupaten Pringsewu sebagai kelompok berisiko menjadi meningkat. Penyuluhan yang berkelanjutan tentang perokok pasif dan dampak yang ditimbulkan khususnya dalam upaya pencegahan infeksi saluran nafas akut pada anak balita sebaiknya terus dilakukan sehingga diharapkan angka kejadian Infeksi saluran nafas akut pada balita dapat menurun.Kata kunci : ISPA, Perokok Pasif, Balita, Lampung
Co-Authors Adhim, Muhammad Risqi Afifah, Syafira Hasna Agustyas Tjiptaningrum Amallia, Rizka Dina Annasya, Benazhir Saninah Asep Sukohar Bayu Anggileo Pramesona Dahlan Susilo Eliza Techa Fattima, Eliza Techa Endah Setyaningrum, Endah Esfandiari, Firhat Ety Apriliana Faisal Yunus Faisal, Hana Khairina Putri Fitria Saftarina Hardika Khusnuliawati, Hardika Intanri Kurniati Khairun Nisa Kirana, Widya Tria Kitagawa, Hiroki Kristiani, Rini Marcellia, Selvi Mayasari, Diana Morfi, Chicy Widya Oktafany Putri, Maharani Ramdini, Dwi Aulia Rika Lisiswanti Riyan Wahyudo Rosa, Emantis Septiani, Linda Soemarwoto, Retno Ariza Suci, Maghfirly Juniarti Eka Tusy Triwahyuni