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Pola Bakteri Ulkus Diabetikum Pada Penderita Diabetes Melitus di RSUD Dr. H. Abdul Moeloek Haula Rizqiyah; Tri Umiana Soleha; Rizki Hanriko; Ety Apriliana
MAJORITY Vol 9 No 2 (2020): MAJORITY
Publisher : Majority

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Abstract

Diabetes mellitus is a term for heterogeneous of metabolism disturbances for which the main finding is chronic hyperglycaemia. In diabetes mellitus, elevated glycaemic levels increases the risk of microvascular and macrovascular complications. These increase risk of further complications such as peripheral neuropathy which can cause foot ulcerations. Diabetic extremity ulcers develop in approximately 15% of people with diabetes and are a leading cause of hospitalization and amputation among such patient. Diabetic foot ulcer infection followed by amputation contribute dramatically not only to the morbidity among persons with diabetes, but are also associated with severe clinical depression and increased mortality rates. The aim of the study was to determine the bacterial profile of diabetic foot ulcer in RSUD Dr. H. Abdul Moeloek. This study was a descriptive study using a cross sectional study. Sampling was conducted at RSUD Dr. H. Abdul Moeloek and examined in Microbiology-Parasitology Laboratorium in Medicine Faculty of Lampung University. The diabetic foot ulcer swab was taken to identified the bacteria. Bacteria were isolated on nutrient agar, blood agar, Mc Conkey agar, and identified using Gram staining and biochemical test. In the 21 diabetic foot patients, 16 were males (76.2%) and 5 were females (23.8%) and grade-II Wagner’s ulcers were predominant, which is deep ulcer without bony involvement or abscess. In the diabetic foot ulcers cases, 85.7% cases had monomicrobial infections while 14.3% cases had mixed bacterial infection. Gram-positive bacteria accounted for 62.5%. Staphylococcus aureus was the most frequent microorganism yielded (58%). Gram-negative rods accounted for 37.5%. Escherichia coli was the most predominant gram-negative organism (17%). Staphylococcus aureus, Staphylococcus epidermidis, Citrobacter freundii, Escherichia coli, and Proteus mirabilis were found in diabetic foot infections in the present study.
Prevalensi Kolonisasi Bakteri Methicillin-Resistant Staphylococcus aureus (MRSA) di Ruang Intensive Care Unit (ICU) Rumah Sakit Umum Daerah Abdul Moeloek Bandar Lampung Hasril Mulya Budiman; Tri Umiana Soleha; Efrida Warganegara; Dwi Indria Anggraini
MAJORITY Vol 9 No 1 (2020): MAJORITY
Publisher : Majority

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Abstract

Methicillin-Resistant Staphylococcus aureus (MRSA) is a bacterium Staphylococcus aureus which has a resistance to methicillin and some beta-lactam antibiotics. MRSA can colonize as normal flora in some parts of the human body, such as the nose, skin, hands, perineum, and other parts of the body. Intensive Care Unit (ICU) is the high risk areas for MRSA transmission. The purpose of this study was to determine the prevalence of MRSA in ICU of Regional General Hospital Abdul Moeloek Bandar Lampung. The method used in this study was cross sectional. The primary data used in this research were obtained by collecting a nasal and hand swab of patients treated in the ICU at one time and then identify the MRSA bacteria in laboratory to determine its prevalence. The results of bacterial identification on the nose and hand specimen showed 15 out of 40 samples tested positive for MRSA (37.50%). The results of the identification of bacteria MRSA shows the prevalence of MRSA colonization of the nose specimen at 17.50%, hand amounted to 32.50%, and which are both positive at 12.50%. Based on the research that has been done, it can be concluded there is a prevalence of colonization of the MRSA bacteria in ICU of Regional General Hospital Bandar Lampung Abdul Moeloek is 37.50%.
Faktor-Faktor Internal Yang Berperan Dalam Keberhasilan Terapi Pasien Terhadap Penyakit Morbus Hansen Di Kota Bandar Lampung Siti Zahnia; Tri Umiana Soleha; Ety Apriliana
MAJORITY Vol 9 No 1 (2020): MAJORITY
Publisher : Majority

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Abstract

Morbus Hansen (MH) is a chronicinfectiousdisease caused by Mycobacterium leprae. Morbus Hansen's disease is a national public health problem in Indonesia. The cure rate in Lampung in 2014 is about 83.3% for PB and 60.1% for MB. The cure rate has not yet reached the target release from treatment, which is >90%. Low achievement of MH cure rate can be caused by patients who’re not regularly taking the medication. The lack of MH cure rate can be caused byseveralfactors, which are externalamd internal factors. This study aimed to determine the internal factors that associated with therapy success of Morbus Hansen's disease in Bandar Lampung. This study is an observational study with cross sectional design.The sample in this study isMH patients who take medication to Puskesmas in Bandar Lampung region, about 42 patients. Data then analyzed using chi-square test. The results showed that out of 42 respondents, the success of MH therapy is bigger on the child's age, female gender, higher education, not working, medication adherence, good knowledge and good socio-economic. From the bivariate analysis, it’s known that there is influence of age (p=0,017), knowledge (p=0,030) and socio-economic on the successful of therapy (p=0.002), while gender, education and employment do not affect the success of the therapy (p = 0.190; p = 0.064; p = 0.355). From six internal factors analyzed in this studythere are only age, level of knowledge and socio-economic thatassociated to the successful therapyof patients withMorbus Hansen's disease.
Identifikasi Mikroorganisme Yang Ditemukan Di Dalam Cairan Pembersih Lensa Kontak Pada Mahasiswa Fakultas Kedokteran Denny Habiburrrohman; Tri Umiana Soleha; Ety Apriliana; Dwita Oktaria
MAJORITY Vol 9 No 1 (2020): MAJORITY
Publisher : Majority

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Abstract

The development and use of contact lenses is increasing rapidly, both in developed and developing countries. In line with that many contact lens users are one of the names of infections in the eye. One of the causes is contamination of contact lens solution. To identify the types of microorganisms found in contact lens solutions in students of the Faculty of Medicine, University of Lampung in 2018. This study used a descriptive observational research type. The study was conducted at the Faculty of Medicine, University of Lampung in June 2018. Samples were contact lens solution, with a total sample of 30 samples. The sample was taken to the Laboratory of Microbiology, Faculty of Medicine, University of Lampung. Samples were identified by bacterial culture, gram staining and biochemical tests. Identification of B. subtilis (22%), Pseudomonas aeruginosa (11%), Staphylococcus aureus (8%), Serratia sp (7%), Klebsiella sp (7%), E.coli (2%) . Of the 60 samples studied, it was found that there were no bacterial growths in 26 samples (43%), and there was bacterial growth in 34 samples (57%)