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Journal : Medula

Identifikasi Bakteri Gram Negatif Penghasil Extended Spectrum Beta-Lactamase (ESBL) Pada Urin Pengguna Kateter di Ruang Rawat Inap Kelas III RSUD Dr. H Abdul Moeloek Bandar Lampung Revina Rifda Amelia; Reyhan Anjani Putri; Tri Umiana Soleha
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.502

Abstract

Urinary catheterization is an action to insert a catheter into the patient's bladder through the urethra used in the hospital. The use of urinary catheters increases the risk of urinary tract infections (UTI) by about 5% every day. The incidence of nosocomial infection is 3 times higher in class III inpatients. According to research bacteria found as a cause of urinary tract infections due to urine catheters have a high enough potential to become a bacterium inhibiting Extended Spectrum Beta-Lactamase (ESBL). ESBL is a mutated β-lactamase enzyme, causing an increase in the enzymatic activity of β-lactamase, so that this enzyme can hydrolyze third generation sefalosporins and aztreonam. To find out the existence of ESBL-producing gram-negative bacteria in the catheter user urine in class III inpatients Dr. H. Abdul Moloek. This study used a categorical descriptive method with a cross sectional approach. The sample in this study were 22 patients who used catheters in class III inpatient rooms. Then the samples were tested for culture, biochemical tests and Double Disc Synergy Test. The results of a study of 22 patients undergoing a culture test found 4 patients with ESBL-producing gram-negative bacteria, 3 Escherichia coli bacteria (75%) and 1 Pseudomonas aeruginosa bacterium (25%) %), from these results the most bacteria producing ESBL is Escherichia coli. The conclusion is the highest amount of ESBL-producing bacteria was Escherichia coli (75%).
Faktor Faktor Yang Mempengaruhi Terjadinya Infeksi Saluran Kemih Sekar Feni Widiyastuti; Tri Umiana Soleha
Medula Vol 13 No 6 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i6.825

Abstract

Urinary tract infection (UTI) is a collective term that describes any infection that involves any part of the urinary tract, include the kidneys, ureters, bladder and urethra. Urinarytract infection is also usually defined as an increase in the number of bacteria limiting 105 CFU or more, with symptoms such as frequent urge to urinate, pain, dysuria. Urinary tract infections can be caused by various types of bacteria. The bacteria that cause urinary tract infections are Escheria coli, Klebsiella sp, Proteus sp, Providensia, Citrobacter, Pseudomonas aeruginosa, Acinetobacter, Enterococsu faecali and Staphylococcus saprophyticus, Staphylococcus aureus, however, the leading cause of UTIs is generally caused by Escheria coli. There are many factors that influence the occurrence of urinary tract infections. The purpose of this literature review is to analyze the etiology and factors that influence the occurrence of UTI. The literature review was carried out through electronic-based journals, namely the Proquest database and Google Schola. The literature used is in accordance with the keywords, namely factors that influence the incidence of UTI. The inclusion criteria were articles published maximum in 2013. Meanwhile, the exclusion criteria were literature published in 2012 and below. Based on the research results obtained regarding. factors that influence the occurrence of urinary tract infections such as female gender, old age, catheter insertion, genital hygiene, comorbid diseases such as diabetes mellitus, hypertension, cerebrovascular disease and general health conditions.