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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin MEDISAINS Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Jurnal Penelitian Pendidikan IPA (JPPIPA) Bioscientia Medicina : Journal of Biomedicine and Translational Research Health and Medical Journal Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Health Sains Indian Journal of Forensic Medicine & Toxicology Open Access Indonesian Journal of Medical Reviews Bioscientia Medicina : Journal of Biomedicine and Translational Research Cermin Dunia Kedokteran Jurnal Impresi Indonesia Journal of Social Research Jurnal Locus Penelitian dan Pengabdian JKKI : Jurnal Kedokteran dan Kesehatan Indonesia MEDICINUS Journal of General Procedural Dermatology and Venereology Indonesia Cermin Dunia Kedokteran

Dharmawan, Nugrohoaji

Departemen Ilmu Kesehatan Kulit Dan Kelamin, Fakultas Kedokteran Universitas Sebelas Maret/ RSUD Dr. Moewardi

Author-ID : 1803352

Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary

Published : 34 Documents Claim Missing Document

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Ulkus Marjolin yang Berkembang dari Ulkus Trofik Kronis pada Pasien Kusta Adniana Nareswari; Harijono Kariosentono; Nugrohoaji Dharmawan; Muhammad Eko Irawanto; Nurrachmat Mulianto
MEDICINUS Vol. 34 No. 2 (2021): MEDICINUS
Publisher : PT Dexa Medica

Marjolin’s ulcer is a malignant complication of chronic ulcer. Changes in ulcer lesions to malignancy can be caused by chronic irritation, infection, decreased vascular variation, and increased expression of proto-oncogene. The most common histopathological form of Marjolin's ulcer is squamous cell carcinoma. A 55-year-old man, complaining of a protruding wound on his left hand that has not healed since three years ago. The patient was diagnosed with leprosy 30 years ago with a history of incomplete treatment. On physical examination, the left palmar region showed solitary ulcer, ±10x8x1.5 cm in size, nodular surface, reddish, hard consistency, with bulging and irregular edge. Slit-skin smear (SSS) examination with Ziehl-Neelsen staining found abundant acid-fast bacilli. Histopathological examination of the ulcer edge shows appearance of epithelial tumor, with differentiated epidermal cells invading the dermis, tumor cells arranged focally and concentrically with a mass of keratin appeared as horn pearl cells. Fite-Faraco staining found abundant M. leprae acid-fast bacilli. Based on the patient’s medical history and clinical examination, patient was diagnosed with Marjolin's ulcer in multibacillary (MB) leprosy. Patient was treated with MB multidrug therapy for 12 months and below-wrist amputation.

Terapi Oral dan Tetes Mata Topikal pada Green Nail Syndrome Putti Fatiharani Dewi; Ambar Aliwardani; Nugrohoaji Dharmawan
MEDICINUS Vol. 34 No. 3 (2021): MEDICINUS
Publisher : PT Dexa Medica

Background: Green nail syndrome is one of the chromonychia caused by infection of Pseudomonas aeruginosa, characterized by onycholysis and greenish-black discoloration of the nail. There were no reports regarding the incidence of green nail syndrome in Indonesia. Predisposing factors for the occurrence of green nail syndrome include onychomycosis, high activity in moist and wet conditions, diabetes mellitus, and immunosuppression. Case: A 51-year-old man complained about greenish-black discoloration on his fingernails. Dermatological examination in 1st and 3rd digit of the right hand, as well as 1st digit of the left hand, found multiple greenish-black discoloration with onychodystrophy. Dermoscopy examination of the affected nails showed greenish-black pigmentation in the distolateral nails with peripheral fading. Culture examination using MacConkey agar showed colonies of greenish-brown pigments. The patient was diagnosed with green nail syndrome and treated with ciprofloxacin 500 mg/day and topical polymixin B eye drops b.i.d. for 3 weeks, resulting in good outcome. Discussion: The diagnosis of green nail syndrome is made based on anamnesis, physical examination, and bacterial culture. showing a distinctive feature. The predisposition factor in this case, is the frequent washing hands habit of the patient up to more than ten times per day. Treatment using topical eye drops facilitates the absorption of active ingredients into the nails.

Kromoblastomikosis Penyakit Jamur yang Terabaikan Danu Yuliarto; Achmad Satya Negara; Harijono Kariosentono; Nugrohoaji Dharmawan; Nurrachmat Mulianto
MEDICINUS Vol. 36 No. 1 (2023): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/medicinus.v36i1.116

Chromoblastomycosis is a deep fungal infection of the skin and subcutaneous tissue caused by pigmented or dematiaceous fungi. This disease is endemic in tropical and subtropical regions such as Asia, Africa, and Latin America. Chromoblastomycosis is more common in adult men who work in agricultural areas, work as gardeners, or as carpenters. The diagnosis of chromoblastomycosis is confirmed by the finding of muriform cells or medlar bodies obtained from skin scrapings, microscopic culture, or tissue histopathological examination. The clinical feature varies, the initial lesion is a papule that spreads slowly over several months or years, and then this lesion will form a plaque with atrophic center. Many patients go undiagnosed at the early stage of the disease because this stage is rarely seen. Treatment of chromoblastomycosis includes surgery for the initial lesion and pharmacological therapy using antifungal agent such as itraconazole, the most commonly used drug for the treatment of chromoblastomycosis. The prognosis for chromoblastomycosis is poor, except on new lesions.

Co-Authors Achmad Satya Negara Adjie, Sugih Primas Adniana Nareswari Adniana Nareswari Ahmad Fiqri Ambar Aliwardani Arie Kusumawardani Arie Kusumawardani Arrosyid, Azhar Aulia Rahman Ayu Kusuma Dewi Bobby Febrianto Brian Wasita Danu Yuliarto Diana, Rina Eka Putra W Ellistasari , Endra Yustin Ellistasari, Endra Yustin Endra Yustin Ellistasari Endy D, Marsita Etty Farida Mustifah Fiqnasyani, Siti Efrida Fiska Rosita Frieda Yanuar Halim Perdana Kusuma Harahap, Irene Jessica Pinarsinta Harijono Kariosentono Heryadi, Fanny Fauziyyah Imroatul Ulya Indah Julianto Indah Julianto Indah Julianto, Indah Irawanto, Muhammad Eko Irene Jessica Pinarsinta Harahap Kamilah, Lian Kariosentono, Harijono Kusumawardani, Arie Marsita Endy D Mawardi , Prasetyadi Moerbono Mochtar Moerbono Mochtar Muhammad Eko Irawanto Muhammad Risman Murastami, Ammarilis Mustifah, Etty Farida Novan Adi Novan Adi Setyawan Novan Adi Setyawan Novan Adi Setyawan Nur Rachmat Mulianto Nurfaiqoh, Elok Nurrachmat Mulianto Octarica, Stella Gracia Oyong Oyong Prasetyadi Mawardi Prasetyadi Mawardi Primisawitri, Pratiwi Prasetya Purwoko, Agus Putra W, Eka Putti Fatiharani Dewi Putti Fatiharani Dewi Rina Diana Rini Hastuti Rini Hastuti Risman, Muhammad Sesia Pradestine Suci Widhiati Suci Widhiati Synthia Sari Toha Triasari Oktavriana Trya Oktaviani Tutik Rahayu TUTIK RAHAYU Ulya, Imroatul Ummi Rinandari Utama, Rahmat Firdaus Dwi Wibisono Nugraha Widhiati, Suci Widyastuti, Zilpa

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