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All Journal Jurnal Penelitian Kesehatan Suara Forikes Health Notions Manuju : Malahayati Nursing Journal 2-TRIK: TUNAS-TUNAS RISET KESEHATAN Jurnal Analis Medika Biosains (JAMBS) Poltekita : Jurnal Ilmu Kesehatan JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan Jurnal Teknokes HEALTHY: Jurnal Inovasi Riset Ilmu Kesehatan Jurnal Pengabdian Kepada Masyarakat Mulawarman JHeS (Journal of Health Studies) Analis Kesehatan Sains (e-Journal) Jurnal Rakat Sehat : Pengabdian Kepada Masyarakat Jurnal Sains Student Research Jurnal Pengabdian Kesehatan Beguai Jejama Health Dynamics Media Penelitian dan Pengembangan Kesehatan Jurnal Teknokes
Endarini, Lully Hanni
Poltekkes Kemenkes Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Evaluation of the Quality of Commercial Control Materials and Homemade Lyophilized on Clinical Chemistry Parameters with the Sigma Metric Method Maulida Azmi Wimasni Inah; Masdiva Putri Hidayah; Anik Handayati; Museyaroh; Lully Hanni Endarini; Edy Haryanto
Jurnal Teknokes Vol. 18 No. 3 (2025): September
Publisher : Jurusan Teknik Elektromedik, Politeknik Kesehatan Kemenkes Surabaya, Indonesia

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Abstract

Control materials are used to maintain the accuracy of testing procedures and the quality of laboratory results. However, commercial control materials are often considered less economical, so an alternative is needed, namely lyophilized human serum. Sigma metric helps improve laboratory operational costs efficiency through control settings and Westgard rule recommendations involving the Total Error Allowable (TEa) value, bias value (d%), and coefficient of variation (CV%). This study aims to determine the quality of commercial control materials and homemade lyophilized materials for blood glucose, uric acid, total cholesterol, and triglyceride parameters based on sigma values. This study used a comparative cross-sectional design. The samples included commercial control materials from one of the primary-level laboratories in Bangkalan District and homemade lyophilized samples from human serum collections. Data Analysis was conducted by statistically comparing the bias value and descriptively comparing the sigma value of commercial control material and homemade lyophilized. The results showed no significant difference in bias value between commercial control material and homemade lyophilized material for all parameters (significance value > α 0,05). The sigma values of commercial control material for blood glucose, uric acid, total cholesterol, and triglyceride parameters were 2.81 (poor), 2.41 (poor), 3.10 (marginal), and 2.14 (poor). The sigma values of the homemade lyophilized were 2.12 (poor), 1.76 (unacceptable), 3.36 (marginal), and 2.08 (poor). Based on the sigma values, the homemade lyophilized material was better for total cholesterol parameters, while the commercial control material was better for blood glucose, uric acid, and triglyceride parameters. It can be concluded that homemade lyophilized can be used as an alternative to commercial control materials, especially for total cholesterol parameters. These findings support the cost efficiency of laboratory operations through the development of more economical homemade lyophilized products that are suitable for use in laboratories.
Characterization of DNA Quality, TPOX Locus, TH01 Locus in Seawater Soaked Nails in Forensic Identification Utomo, Ratno Tri; Endarini, Lully Hanni; Yudianto, Ahmad; Christyaningsih, Juliana
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 3 (2023): November
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i3.3028

Abstract

Forensic science is multiplying. One of them is the identification of events at sea. Of course, the victim’s body can be submerged in seawater for days so that components in seawater can affect the victim’s body. This research aimed to see the effect of storage time on the level and purity of DNA in nail samples. Identification of nail DNA using the Polymerase Chain Reaction (PCR) method. The DNA purity test examines nail samples using a spectrophotometer read at 260 and 280 nm wavelengths. Measurement of DNA levels using the PCR instrument on the STR TPOX locus, the result was 32.02 ug/uL on positive control, 36.73 ug/uL in seawater immersion on the 2nd day, 35.35 ug/uL in seawater immersion on the 7th day, and 34.5 ug/uL in seawater immersion on the 20th day. At the STR TH01 locus, the result was 32.155 ug/uL on positive control, 38.05 ug/uL on the 2nd day of immersion in seawater, 35.18 ug/uL on the 7th day, and 33.88 ug/uL on the 20th day. Results Examination of the Total Plate Number of seawater on the 2nd day, 7th day, and 20th day of immersion found no colonies of germ colony growth. This study obtained sufficient DNA purity from the 2nd day, 7th day and 20th day. So that the samples could be analyzed for DNA levels, the result obtained from the study showed a decrease in DNA levels at the TPOX Locus and TH01 Locus from the 2nd day, 7th day, and 20th day.
EFEKTIVITAS PEMBERIAN TABLET TAMBAH DARAH TERHADAP KADAR HEMOGLOBIN PADA SISWI Susanti, Reni; Krihariyani, Dwi; Endarini, Lully Hanni; Suliati, Suliati
HEALTHY : Jurnal Inovasi Riset Ilmu Kesehatan Vol. 4 No. 2 (2025)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/healthy.v4i2.6391

Abstract

ABSTRACT Iron deficiency anemia is a common nutritional problem among adolescent girls in developing countries such as Indonesia, affecting both health and academic performance. The government has implemented a school-based iron supplementation program to address this issue. This study aims to evaluate the effectiveness of iron tablet supplementation in increasing hemoglobin levels among 10th-grade female students at MAN 3 Magetan. The study used a quasi-experimental design with a one-group pre-test and post-test approach. A total of 122 students aged 15–18 years participated based on inclusion criteria and parental consent. The intervention involved weekly iron tablet supplementation for three months. Hemoglobin levels were measured before and after the intervention using a HemoCue device, and data were analyzed using the Wilcoxon Signed-Rank test. The results showed a significant increase in hemoglobin levels after the intervention (p < 0.05). Prior to supplementation, 39% of the students were anemic, which decreased to 8% after the intervention, with 92% having normal hemoglobin levels. These findings indicate that regular iron supplementation effectively improves hemoglobin levels and reduces anemia prevalence. The program should be continued with sustained nutrition education and monitoring of compliance to ensure long-term effectiveness. ABSTRAK Anemia defisiensi zat besi merupakan masalah gizi yang umum pada remaja putri di negara berkembang seperti Indonesia, berdampak pada kesehatan dan prestasi belajar. Pemerintah telah menjalankan program pemberian tablet tambah darah (TTD) di sekolah sebagai upaya pencegahan. Penelitian ini bertujuan mengevaluasi efektivitas pemberian TTD terhadap peningkatan kadar hemoglobin pada siswi kelas X di MAN 3 Magetan. Desain penelitian menggunakan kuasi eksperimen dengan pendekatan one group pre-test dan post-test. Sebanyak 122 siswi usia 15–18 tahun menjadi responden berdasarkan kriteria inklusi dan persetujuan orang tua. Intervensi berupa pemberian TTD dilakukan seminggu sekali selama tiga bulan. Kadar hemoglobin diukur sebelum dan sesudah intervensi menggunakan alat HemoCue, dan data dianalisis dengan uji Wilcoxon Signed-Rank. Hasil menunjukkan peningkatan signifikan kadar hemoglobin setelah intervensi (p < 0,05). Sebelum intervensi, 39% siswi mengalami anemia, sementara setelahnya hanya 8%, dengan 92% memiliki kadar hemoglobin normal. Temuan ini menunjukkan bahwa pemberian TTD secara rutin efektif meningkatkan kadar hemoglobin dan menurunkan prevalensi anemia. Program ini perlu dilanjutkan secara berkelanjutan dengan edukasi gizi dan pemantauan kepatuhan konsumsi untuk hasil jangka panjang.
Co-Authors ., Pestariati A'yunin, Zahratin Nisa' Ahmad Yudianto Alda Nugrahini Anggraini, Anita Dwi Anita Dwi Anggraini Anita Dwi Anggraini Arifin, Syamsul Ayu , Puspitasari Ayu Puspitasari Christ Kartika Rahayuningsih Dewi Ika , Pratiwi Diah Titik Mutiarawati Diah Titik Mutiarawati Edy Haryanto Edy Haryanto Era Fitria Yunita Evy Diah Woelansari Farah Adelia Qotrunnada Handayati, Anik Hardian Bimanto Imat Rochimat Indah Lestari Indah, Lestari Indira Ayuni Sri Pramasti Istanto, Wisnu Juliana Christyaningsih Junaedi, Winda Rachmawati Krihariyani, Dwi Liliek Soetjiatie Luthfi Rusyadi Mamik Mamik Mamik Mamik Masdiva Putri Hidayah Maulida Azmi Wimasni Inah Minarti Minarti Minarti Minarti Museyaroh, Museyaroh Mutiarawati, Diah Titik Mutiarawati, Diah Titik Nabilah, Musholli Himmatun Nada Nabilah Wulandari Nadeak, Juan Carlos Nuri Handayani Pratiwi Dewi Ika Rahma Faisa Talitha Reni Susanti Retno Sasongkowati Retno Sasongkowati Rina Idawati Sari, Sintia Mustika Sasongkowati, Retno Shofan Ilham Sulaiman Sri Sulami Endah Astuti Sri Utami Sri, Tovani Suhariyadi Suhariyadi Suhariyadi Suhariyadi Sulaiman, Shofan Ilham Suliati Suliati Suliati Suliati Suliati, Suliati Suliati, Suliati Syamsul Arifin Talitha, Rahma Faisa Titin Muslihatin, Titin Utomo, Ratno Tri Vemy Rahmany Kurniawan Wisnu Istanto Yasmin, Aisha Amelia Yuni Eka Cahyana Yuyun Dwi Wahyuni