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All Journal Jurnal Review Pendidikan dan Pengajaran (JRPP) International Journal Of Science, Technology & Management (IJSTM) Bima Abdi: Jurnal Pengabdian Masyarakat Jurnal EduHealth Mejuajua Jurnal Farmanesia Jurnal Pengabdian Kepada Masyarakat Sisthana Jurnal Nusantara Berbakti Nusantara Scientific Medical Research Journal Journal of Pharmaceutical and Sciences. Jurnal Farmasi SYIFA Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Journal of Innovative and Creativity Jurnal ABDIMAS MUTIARA Compromise Journal : Community Proffesional Jurnal Siti Rufaidah JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL
Monica Suryani
Universitas Sari Mutiara Indonesia
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Lip Balm Dari Minyak Kanola (Rapeseed Oil) Sebagai Pelembab Bibir Masyitah, Cut; Harahap, Astari Della Paramitha; Suryani, Monica
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

UJI AKTIVITAS ANTIJAMUR EKSTRAK N-HEKSAN, ETIL ASETAT DAN ETANOL DAUN JERUK MANIS (Citrus sinensis (L.) Osbeek) TERHADAP JAMUR Candida Aldicans Dan Pityrosporum ovale Suryani, Monica; br Ginting, Grace Anastasia; Ruth Christiani N Daely
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 1 No. 1 (2019): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Infeksi jamur merupakan salah satu penyakit kulit yang banyak dialami oleh masyarakat. Candida albicans merupakan mikroorganisme yang menyebabkan sariawan dan keputihan pada wanita. Pityrosporum ovale adalah mikroorganisme yang menjadi penyebab utama ketombe. Tanaman jeruk manis (Citrus sinensis (L.) Osbeck) memiliki banyak fungsi karena memiliki kandungan senyawa aktif yang mampu digunakan sebagai antibakteri, antijamur, antioksidan, antikanker dan antikolesterol. Tujuan penelitian ntuk mengetahui adanya aktivitas antijamur dan mengetahui adanya perbedaan hasil uji aktivitas antijamur ekstrak n-heksan, etil asetat dan etanol daun jeruk manis (Citrus sinensis (L.) Osbeck) terhadap Candida albicans dan Pityrosporum ovale. Daun jeruk manis diekstraksi menggunakan metode maserasi dengan pelarut n-heksan, etil asetat dan etanol. Serbuk simplisia diskrining untuk mengetahui kandungan fitokimianya. Ekstrak etanol dibuat dalam berbagai konsentrasi yaitu 20 mg/ml, 40 mg/ml dan 80 mg/ml dan diuji aktivitas antijamurnya terhadap C. albicans dan P. ovale. Uji aktivitas antijamur dilakukan dengan metode difusi cakram (Kirby-Bauer).Hasil penelitian menunjukkan bahwa simplisia daun jeruk manis mengandung alkaloid, saponin, flavonoida, tanin dan steroid/triterpenoid. Ekstrak n-heksan, etil asetat dan etanol daun jeruk manis mempunyai aktivitas antijamur. Ekstrak n-heksan terhadap jamur Candida albicans dengan konsentrasi 80 mg/ml (11,32±0,06mm), ekstrak etil asetat 80 mg/ml (19,68±0,12mm) dan ekstrak etanol 80 mg/ml (15,38±0,08mm). Jamur Pityrosporum ovale terhadap ekstrak n-heksan 80 mg/ml (10,33±0,02mm), ekstrak etil asetat 80 mg/ml (17,59±0,05mm), dan etanol 80 mg/ml (14,25±0,07mm). Ekstrak n-heksan, etil asetat dan etanol daun jeruk manis memiliki aktivitas sebagai antijamur, dari ketiga larutan yang diuji ekstrak etil asetat dan etanol memiliki kemampuan yang baik dalam menghambat pertumbuhan jamur Candida albicans dan Pityrosporum ovale.
Formulasi dan Evaluasi Sediaan Body Scrub dari Ekstrak Etanol Daun Alpukat (Persea Americana Mill) Kombinasi Beras Ketan Putih (Oryza Sativa l Var Glutinous) Sebagai Pelembab Kulit Fridelly Mairani; Alya Izzani; Monica Suryani; Devina Chandra
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.7141

Abstract

Masyarakat sekarang sangat mendambakan kecantikan yang alami salah satunya dengan memiliki kulit yang bersih dan lembab. Untuk mendapaktkan kulit yang sehat,bersih dan lembab masyarakat dapat menggunakan sediaan kosmetik Body scrub yang berasal dari bahan alam maupun sintetis. Body scrub dapat membantu menutrisi kulit dengan tambahan bahan-bahan yang diperoleh dari alam seperti tumbuh-tumbuhan. Salah satu kandungan kimia yang terdapat pada daun alpukat yaitu Quersetin tersebut dapat didefinisikan sebagai senyawa kelompok flavonol terbesar dan termasuk senyawa flavonoid yang paling efektif untuk dapat melembabkan kulit dan juga sebagai antioksidan yang dapat menangkal radikal bebas. Penelitian ini bertujuan untuk membuat sediaan Body scrub dari ekstrak etanol daun alpukat yang dapat melembabkan kulit. Metode yang digunakan dalam penelitian ini yaitu metode eksperimental. Pembuatan ekstrak etanol daun alpukat dengan cara ekstraksi metode maerasi dan menggunakan pelarut etanol 96%. Konsentrasi kandungan daun alpukat yang terkandung bervariasi yaitu, 3%, 5% dan 7%. Hasil penelitian menunjukkan bahwa ekstrak etanol daun alpukat dapat diformulasikan kedalam sediaan Body scrub yang dapat melembabkan kulit, dan sediaan tersebut homogen, sediaan yang stabil uji pH yang dihasilkan 5,12-6,00. Sediaan Body scrub tidak menimbulkan iritasi pada kulit uji viskositas yang dihasilkan 2.573-3.334 cPs uji daya sebar rentan 5,76-5,93 cm uji tipe emulsi menunjkkan tipe M/A uji daya lekat yang dihasilkan 44-61 detik. Pada uji kelembaban konsentrasi 3%,5% dan 7% dapat melembabkan kulit, semakin tinggi konsentrasi ekstrak daun alpukat, semakin tinggi tingkat kelembaban yang di peroleh. Sediaan Body scrub F3 dengan konsentrasi 7% yang paling disukai (sangat suka) dikarenakan lebih dapat melembabkan kulit. Secara keseluruhan dapat disimpulkan bahwa ekstrak etanol daun alpukat dapat diformulasikan kedalam sediaan Body scrub dan memiliki kemampuan melembabkan kulit.
Bakti Sosial Pengobatan Gratis dan Penyuluhan Pengetahuan Tentang Tanaman Obat Keluarga (TOGA) Di Sekolah Tanjung Pura Langkat Suryani, Monica; Jon Kenedy Marpaung; Suharyanisa Suharyanisa; Mestika Lumbantoruan
Jurnal Nusantara Berbakti Vol. 1 No. 3 (2023): Juli : Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v1i3.193

Abstract

Family medicinal plants (abbreviated as TOGA) are home-cultivated plants that have medicinal properties. A family medicine garden is essentially a plot of land, whether in the yard, garden or field, which is used to cultivate medicinal plants in order to meet the family's need for medicines. The purpose of this service activity is to provide social services for free medical treatment and dissemination of knowledge about family medicinal plants (TOGA) at the Tanjung Pura Langkat school. This method of activity involved lecturers at the Sari Mutiara Indonesia University, the regent, the sub-district head and the people of Langkat. The result of this activity is that the community service team hopes that the community can get free medication and knowledge about family medicinal plants. Based on the results of the Community Service activities carried out, these activities went well and the community received treatment and received knowledge about family medicinal plants so that the community could improve their health.
Standardization of Rhizome Simplicia from the Zingiberaceae Family in Terms of Methods and Quality: A Review Silalahi, Yosy Cinthya Eriwaty; Surbakti, Christica Ilsana; Suharyanisa, Suharyanisa; Suryani, Monica; Ulfata, Zikri; Panjaitan, Grace Emmas Sondang; Marbun, Eva Diansari
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 02 (2025): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v3i02.128

Abstract

Simplicia rhizomes from the Zingiberaceae family are important raw materials in the traditional medicine industry, as they contain bioactive compounds such as flavonoids, alkaloids, and tannins. The quality of simplicia is strongly influenced by post-harvest processing methods, particularly drying. This study aims to systematically review the quality of Zingiberaceae rhizome simplicia based on ten national scientific journals published between 2015 and 2024. The method employed was a literature study using a qualitative descriptive approach, evaluating specific quality parameters (organoleptic characteristics, solubility, and phytochemical tests) and non-specific parameters (moisture content, ash content, and microbial contamination) according to the Indonesian Herbal Pharmacopoeia. The results indicate that oven drying at 50–60 °C for 24–48 hours produces the best-quality simplicia, characterized by moisture content below 10%, ash content within acceptable limits, and high flavonoid levels. Other drying methods, such as sun drying and natural air drying, showed more variable outcomes and in some cases exceeded standard limits, particularly in acid-insoluble ash levels and microbial contamination. Several simplicia samples obtained from traditional markets did not meet quality standards due to suboptimal washing and storage processes. This study concludes that simplicia quality standardization must comprehensively address technical stages from washing to drying. The use of extracts is more strongly recommended than raw simplicia to ensure consistency, stability, and safety of herbal products. Strict quality standards are essential to support the effectiveness of traditional medicines derived from Zingiberaceae.
Jurnal Review: Pengaruh Suatu Zat Terhadap Sistem Dalam Tubuh Dari Jamu, Obat Herbal Terstandar, Dan Fitofarmaka Serta Manfaatnya Sebagai Antiinflamasi Sapitri, Alfi; Marbun, Eva Diansari; Suryani, Monica; Fikri, Naufal Noli; Anggraini, Rania Ultah; Ningtia, Ayu Cahya
Jurnal Farmasi SYIFA Vol 4 No 1 (2026): Jurnal Farmasi SYIFA
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jfs.v4i1.986

Abstract

Pemanfaatan jamu, Obat Herbal Terstandar (OHT), dan fitofarmaka di Indonesia terus berkembang seiring meningkatnya kebutuhan masyarakat terhadap terapi berbasis bahan alam yang dinilai lebih aman dan mudah diakses. Ketiga kategori herbal tersebut memiliki tingkat pembuktian ilmiah yang bermanfaat sebagai antiinflamasi, sehingga digunakan telaah sistematis untuk menilai aktivitas biologis dan manfaat kesehatannya berdasarkan penelitian terkini. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis pengaruh zat aktif alkaloid,flavonoid, curcuminoid,steroid,saponin,tanin dan senyawa metabolik lainnya dalam jamu,OHT,dan fitofarmaka terhadap sistem tubuh manusia maupun hewan yang diujikan secara klinik maupun praklinik yang berpotensi aktivitas antiinflamasi berdasarkan studi literatur lima tahun terakhir. Metode yang digunakan adalah telaah sistematis yang meliputi penelusuran literatur, seleksi artikel berdasarkan kriteria inklusi dan eksklusi, ekstraksi data, serta penyusunan hasil dalam bentuk tabel kualitatif. Penelitian yang dianalisis mencakup model uji in vitro, in vivo, hingga uji klinis sesuai golongan produknya. Hasil telaah menunjukkan bahwa beberapa bahan jamu seperti rimpang temulawak, ashitiba dan sambiloto terutama diuji menggunakan model in vitro serta dengan penghambatan enzim siklooksigenase COX-1 dan COX-2 hasilnya memperlihatkan aktivitas antiinflamasi. Pada kategori OHT seperti  daun telang, kombinasi rimpang kunyit dengan kurma,meniran,sambiloto dan kombinasi rimpang kencur dengan daun srikaya memberikan aktivitas antiinflamasi dengan kandungan kandungan zat aktif flavanoid dan senyawa fenolik lainnya melalui penelitian secara in vitro dan in vivo. Dan pada kategori fitofarmaka seperti daun jambu biji dan phyllantus niruri juga memberikan aktivitas antiinflamasi dengan kandungan zat aktif flavanoid dan metabolik lainnya melalui penelitian secara in vivo maupun in vitro dan uji klinis terbatas. Sementara itu,. Secara regulatif, BPOM No. 32 Tahun 2019 berperan memastikan mutu serta keamanan produk herbal. Jamu, OHT, dan fitofarmaka memiliki suatu zat yang relevan sebagai antiiinflamasi.
Artikel Review: Uji Keamanan dan Toksisitas Obat Herbal dalam Pengembangan Jamu, OHT, dan Fitofarmaka Monica Suryani; Alfi Safitri; Eva Diansari Marbun; Ade Irma Suryani; Cut Alvida Zura
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1393

Abstract

Background: Safety and toxicity testing are essential stages in the development of herbal medicines to ensure therapeutic efficacy without causing adverse effects. In Indonesia, herbal products are classified into traditional herbal medicines (jamu), Standardized Herbal Medicines, and phytopharmaceuticals, each requiring different levels of scientific evidence for safety and efficacy. Objective: This study aims to review the results of safety and toxicity testing of herbal medicines in the development of jamu, Standardized Herbal Medicines, and phytopharmaceuticals in Indonesia over the last five years (2020–2025). Methods: This study employed a descriptive, qualitative literature review. Scientific articles were systematically retrieved from the Garuda, Neliti, Sinta, and Google Scholar databases using relevant keywords related to herbal medicine safety and toxicity testing. A total of twelve peer-reviewed research articles published between 2020 and 2025 met the inclusion criteria. The reviewed studies involved in vivo, in vitro, and in silico testing methods, with toxicity parameters including LD₅₀, LC₅₀, biochemical markers, and histopathological changes. Results: The findings indicate that in vivo testing is the most frequently applied method and generally demonstrates a high safety profile for most herbal preparations. Jamu products are considered safe based on empirical use and standardized raw materials. Standardized Herbal Medicines demonstrate safety through acute and subchronic toxicity evaluations. At the same time, phytopharmaceuticals exhibit the highest level of safety through comprehensive testing using combined in vivo, in vitro, and in silico approaches. Most herbal ingredients fall into the non-toxic to mildly toxic category at high doses. Conclusion: Overall, the reviewed evidence suggests that Indonesian herbal medicines, including jamu, Standardized Herbal Medicines, and phytopharmaceuticals, are generally safe when used appropriately. Strengthening multidisciplinary toxicological approaches and implementing pharmacovigilance principles are essential to ensure long-term safety and support the development of evidence-based national herbal medicines.
Sosialisai Tentang Pentingnya Vitamin C Untuk Kesehatan Tubuh Dan Donor Darah Di Kecamatan Medan Helvetia, Kota Medan Monica Suryani; Manahan Situmorang; Natanael Priltius
Compromise Journal Community Proffesional Service Journal Vol. 1 No. 4 (2023): Compromise Journal : Community Proffesional Service Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/compromisejournal.v1i4.194

Abstract

The important role of ascorbic acid or Vitamin C in the body is for metabolic processes and tissue repair. Antioxidants from Vitamin C can help protect cells from free radicals. Vitamin C can protect skin and produce collagen. Collagen is a natural protein in the body that forms the structure of the skin, whose production can decrease due to free radicals and aging. Vitamin C can maintain collagen production so that skin looks healthy and firm. Therefore, Vitamin C can work to maintain beauty and health. The highest daily dose of vitamin C is 1,000 milligrams/day. In this service activity, two activities were carried out separately, namely socialization about the importance of Vitamin C for body health and blood donation in Medan Helvetia District, Medan City to provide information to residents of Medan Helvetia District regarding the importance of Vitamin C for body health. Blood donation is also carried out to have many impacts both on the health of the donor and the recipient. This activity was also carried out to increase awareness regarding the health benefits of consuming Vitamin C.
Formulasi Sediaan Body Scrub Ekstrak Etanol Daun Salam (Syzygium Polyanthum (Wight.) Walp) dan Serbuk Beras Putih (Oryza sativa L.) Sebagai Pelembab Kulit Monica Suryani; Julia Susanti; Dumartina Hutauruk
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v1i4.558

Abstract

Body scrub is a pharmaceutical preparation in the form of a beauty product that functions to smooth the skin of the body and remove damaged skin cells with the help of scrubs. Bay leaf (Syzygium polyanthum (Wight.)Walp) and white rice powder (Oryza sativa L.) are plants that are widely used to maintain health, as a traditional medicine and also as an antioxidant. The research method carried out is experimental. The purpose of this study was to formulate ethanol extracts of bay leaf (Syzygium polyanthum (Wight.)Walp) and white rice powder (Oryza sativa L.) in the form of Body Scrub preparations with concentrations 2, 4, and 6 that can be used as a skin moisturizer. The extract sample uses ethanol solvent, which will be formulated into the form of a Body Scrub preparation, then an examination of the physical quality test of the preparation, irritation test, hedonic test, moisturiser effectiveness test using a skin moisture analyzer is carried out. The results of this study show that the ethanol extract of bay leaf (Syzygium polyanthum) and white rice powder (Oryza sativa L.) can be formulated as a Body Scrub preparation that has met the physical quality requirements of the preparation which has a semi-solid shape, a more concentrated preparation color and a distinctive aroma of bay leaf extract. The preparation shows a homogeneous composition, M/A cream type, spread power range 5.7-6.2 cm, viscosity range 3,800- 4000 cPs, pH 6.4-6.7, non-irritating to the skin and stable in storage for 4 weeks of storage, hedonic value that is very preferred by researchers on the Body scrub F3 preparation. The effectiveness test showed an increase in humidity of 31.59%, which was the best in the preparation of F3 concentration. It can be concluded that the ethanol extract of bay leaf (Syzygium polyanthum (Wight.)Walp) and white rice powder (Oryza sativa L.) can be formulated in Body Scrub preparations that have met the physical quality requirements of the preparation as a skin moisturizer at a concentration of 6%.
Co-Authors Ade Irma Suryani Alfi Safitri Alya Izzani Anggraini, Rania Ultah Annisazikra, Cut Ariani, Ananda br Ginting, Grace Anastasia Chandra, Devina Christica Ilsana Surbakti Cut Alvida Zura Cut Masyitah Thaib Cut Masyithah Thaib Cut Masyithah Thaib Daely, Ruth Christiani N Devina Chandra Dhea Nur Fadhilah Dumartina Hutauruk Fentiana, Nina Fikri, Naufal Noli Fitri, Raissa Fridelly Mairani Fridelly Mairani Apt Hadi, Novia Silvana Harahap, Astari Della Paramitha Hestina, Hestina Ivan Elisabeth Purba Jon Kenedy Marpaung Jon Kennedy Marpaung Julia Susanti Manahan Situmorang Manik, Tumpak Rudi Aman Marbun, Eva Diansari Masyitah, Cut Mestika Lumbantoruan Natanael Priltius Ningtia, Ayu Cahya Novia Silvana Hadi Panjaitan, Grace Emmas Sondang Pasaribu, Yusuf Gunawan Priltius, Natanael Putri Sion Simbolon Ruth Christiani N Daely Sapitri, Alfi Sarumaha, Vivid Angelina Sinaga, Johannes Sirait, Citrawani Enjelina Siti Nurbaya Sitorus, Binsar Sitorus, Elly Sri Wahyuni Suharyanisa Suharyanisa Suharyanisa Surbakti, Christica Ilsana Tandiono, Steven Thaib, Cut Masyithah Ulfata, Zikri Utama, Rezza Fikrih Waruwu, Nia Florentina Yosy Cinthya Eriwaty Silalahi