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HUBUNGAN HBA1C, MIKROALBUMINURIA DAN KOLESTROL DENGAN ESTIMASI GLOMERULAR FILTRASION RATE (GFR) PADA PASIEN DIABETES MELLITUS TIPE 2 Akbar Wardhana; Iin Novita Nurhidayati Mahmuda; Sulistyani , Sulistyani; Sahilah Ermawati; Metana Puspitasari; Raafika Studiviani Dwi Binuko
Journal of Innovation Research and Knowledge Vol. 4 No. 2: Juli 2024
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v4i2.8068

Abstract

Nefropati diabetik merupakan salah satu komplikasi mikrovaskuler diabetes mellitus yang disebabkan oleh kerusakan ginjal dan dapat mengakibatkan gagal ginjal terminal dan dapat dideteksi dengan menghitung estimasi GFR. Penelitian ini bertujuan untuk mengetahui hubungan Hba1C, mikroalbuminuria dan kolestrol dengan estimasi glomerular filtrasion rate (GFR) pada pasien diabetes mellitus tipe 2. Penelitian ini menggunakan desain penelitian analitik observasional dengan pendekatan cross-sectional. Penelitian ini dilakukan di Puskesmas Gatak, Kabupaten Sukoharjo, Jawa Tengah. Populasi dalam penelitian ini yaitu semua pasien prolanis yang menderita DM dan rutin kontrol di Puskesmas Gatak yang memenuhi kriteria. Sampel pada penelitian ini merupakan semua penderita DM yang memiliki dengan jumlah sebanyak 65 sampel. Teknik Analisis data yang digunakan pada penelitian ini dengan menggunaan uji Chi-Square. Berdasarkan hasil penelitian, diketahui bahwa (1) ada hubungan HbA1C dengan estimasi GFR pada pasien diabetes mellitus tipe 2 dengan p-value sebesar 0,040 (<0,05). (2) Ada hubungan antara Mikroalbuminuria dengan estimasi GFR pada pasien diabetes mellitus tipe 2 dengan p-value sebesar 0,035 (<0,05). Ada hubungan kolestrol dengan estimasi GFR pada pasien diabetes mellitus tipe 2 dengan p-value sebesar 0,016 (<0,05). Sehingga dapat disimpulkan bahwa terdapat hubungan Hba1C, mikroalbuminuria dan kolestrol dengan estimasi glomerular filtrasion rate (GFR) pada pasien diabetes mellitus tipe 2.
THE SEVERITY OF COVID-19 IS ASSESSED FROM D-DIMER AND PLATELET LEVELS Putra, Catur Permana; Basuki, Sri Wahyu; Mahmuda, Iin Novita Nurhidayati; Dwi, Raafika Studiviani
Indonesian Journal of Health Science Vol 8 No 1 (2024): March
Publisher : Universitas Muhammadiyah Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24269/ijhs.v8i1.6736

Abstract

This research was conducted with purpose to analyse the association between D- dimer and thrombocyte levels for severity of COVID-19. Researchers used cross sectional method on 57 COVID-19 patients at the private hospital in Surakarta on the period June to September 2021. Data were taken using total sampling with patients who fulfil the criteria and using Spearman test to analyse the association between D-dimer and platelet levels on the severity COVID-19. The characteristics of the respondents studied were an average age was 57 years, male is more dominant than female with a total of 35 (61.4%), the average severity of respondents was seriously ill (with an average oxygen saturations of 89.39%), the dominant D-dimer level of the respondent is increased with an average of 1699.4 ng/ml, and the dominant platelet level of the respondent was normal with an average of 281.360/µl. Results of the analysis with spearman test obtained significance (p-value) 0.560 for the association between D-dimer and severity of COVID-19, while for the association between platelets and severity of COVID-19, significance (p-value) 0.475 were obtained. From the results can be drawn the conclusion there is no association between D-dimer or platelet levels on the severity of COVID-19 disease. 
Perempuan Usia Muda Penderita DM Tipe 2 dengan Multikomplikasi: Laporan Kasus Adhalia, Lian; Mahmuda, Iin Novita Nurhidayati
Cermin Dunia Kedokteran Vol 51 No 12 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i12.1090

Abstract

Type 2 diabetes mellitus is a progressive chronic metabolic disease characterized by an increase in blood sugar due to insulin resistance. Uncontrolled diabetes will cause various acute and chronic complications. The case is a young DM patient with complications of hyperosmolar hyperglycemia status, cerebral ischemia, and pressure ulcers.
Macrovascular and Microvascular Complications of Diabetic Patients: Study form in Gatak Primary Health Care, Sukoharjo, Indonesia Iin Novita Nurhidayati Mahmuda; Metana Puspitasari; Sahilah Ernawati; Sulistyani Sulistyani; Rada Citra Saputra
Althea Medical Journal Vol 13, No 2 (2026)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v13n2.4401

Abstract

Background: Diabetes is a major global health problem, and Indonesia being one of the countries with high prevalence. Fasting plasma glucose (FPG) and HbA1c are the main biomarkers used to assess glycaemic control. Screening for macrovascular and microvascular complications is necessary for early intervention to prevent permanent disability. This study aimed to determine the incidence of macrovascular and microvascular complications in diabetic patients in primary health care.Methods: A descriptive cross-sectional study was conducted from July to September 2022 among patients with diabetes who routinely attended Gatak Primary Health Care. Screening for macrovascular complications included PAD with Ankle-Brachial Index assessment; whereas the microvascular complications using monofilament testing for neuropathy, eye examination for retinopathy, and microalbuminuria for nephropathy.Result: Among 65 patients with diabetes, most were female (83.1%), with a mean age of 62.43±9.47 years. The mean fasting plasma glucose (FPG) was 192.62±86.92 mg/dl, and the mean HbA1c was 12.55±3.59%. Both macrovascular complication (PAD 32.3%) and microvascular complications (retinopathy 57.1%, neuropathy 44.9%, nephropathy 49.2%) were identified, demonstrating the burden of diabetes-related outcomes in primary care.Conclusion: Macrovascular and microvascular complications were highly prevalent among patients with diabetes in primary care, with microvascular complications occurring more frequently. These findings indicate that inadequate glycaemic control contributes substantially to complication rates.
A Technical Approach to Anesthesia in the Case of Tonsillectomy Cahyo, Febrian Dwi; Sutanto, Bambang; Mahmuda, Iin Novita Nurhidayati
Solo Journal of Anesthesi, Pain and Critical Care (SOJA) Vol 3, No 1 (2023): April 2023
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/soja.v3i1.60444

Abstract

Background: Tonsillectomy is the most common surgical procedure performed by an ENT doctor (Throat Nose Ear) in children. This surgery can cause pain, bleeding and swelling in the injured throat. Patient may complain of pain, difficulty swallowing, eating, drinking disorders, nausea and vomiting and fall into a dehydrated state. This can reduce patient satisfaction.Discussion: Postoperative pain management of tonsillectomy is  a concern both by the ENT doctor and by the anesthesiologist. The high incidence of post-tonsillectomy pain or anxiety increases the risk of secondary post-tonsillectomy bleeding. It is necessary to know the mechanism of post operative pain and the negative impact of pain.Conclusion: Doctors should give attention to reduce postoperative pain and choose a rational analgesic to overcome post operative tonsillectomy pain.
Correlations between Age and Hypertension on Diabetic Foot Ulcer Vitania Marsya; Iin Novita Nurhidayati Mahmuda; Nining Lestari; Safari Wahyu Jatmiko
Indonesian Journal of Medicine Vol. 8 No. 2 (2023)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2023.8.2.622

Abstract

Background:  Diabetic foot ulcer is a wound located on the foot of a diabetic patient, which is related to peripheral neuropathy or arterial disease. Hypertension can be related to diabetic foot ulcer by its mechanism that caused peripheral artery disease. Age also can be the one of risk factors for diabetic foot ulcers, because aging occurs a reduction of insulin secretion, even insulin resistance. Insulin resistance occurs in macroangiopathy. The purpose of this study is to determine the correlation between age and hypertension with diabetic foot ulcers.Subjects and Method:  This was a cross-sectional study conducted at Arafah Islamic Hospital Rembang, Central Java. The dependent variable is diabetic ulcers. The independent variables were age and hypertension. A sample of diabetic patients using medical records from January 2022-June 2022. Data were collected using purposive sampling and analyzed using the Chi-Square test, and regression logistic test.Results:  Significant correlation was found between age (OR= 3.80; 95% CI= 1.38 to 10.57; p&lt;0.001) and hypertension (OR= 8.12; 95% CI= 2.70 to 24.40; p&lt;0.001) with a diabetic foot ulcer.Conclusion:  There is a significant correlation between age and hypertension with diabetic foot ulcers.Keywords:  age, hypertension, diabetes, diabetic foot ulcers.Correspondence:  Nining Lestari. Bachelor of Medicine, Muhammadiyah University of Surakarta. Jl. A. Yani, Mendungan, Pabelan, Kartasura, Sukoharjo 57162, Central Jawa, Indonesia. Email: nl209@ums.ac.id. Mobile: +62852-2939-0353Indonesian Journal of Medicine (2023), 08(02): 179-185https://doi.org/10.26911/theijmed.2023.08.02.07 
Pola Resistensi Bakteri Penyebab Ulkus Diabetikum terhadap Antibiotik di Salah Satu Rumah Sakit Swasta di Surakarta Iin Novita Nurhidayati Mahmuda; Devi Usdiana Rosyidah; Flora Ramona Sigit Prakoeswa; Yulia Intan Kania; Ishmah Nur Faizah; Fathiyya Noor Afifah; Andri Sugeng Prasetyo
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 10, No 1 (2025)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v10i1.85091

Abstract

Infeksi ulkus diabetikum termasuk sebuah komplikasi lanjutan dari diabetes melitus yang masih terus meningkat kasusnya. Apabila belum ditangani secara cepat akan memperlaju tingkat keparahan infeksi. Tujuan penelitian ini untuk mengetahui pola resistensi bakteri penyebab ulkus diabetikum terhadap antibiotik pada pasien ulkus diaetikum. Jenis penelitian menggunakan deskriptif observasional. Sistem kompak VITEK 2 digunakan untuk identifikasi bakteri dan pengujian kerentanan antimikroba sesuai petunjuk. Kemudian, suspensi untuk inokulasi kartu AST GP 71 yang digunakan untuk uji kerentanan obat dilakukan dengan memindahkan 280µL suspensi kultur dari suspensi pertama ke dalam 3mL larutan garam steril untuk memperoleh kekeruhan akhir 10 CFU/mL. Hasil penelitian didapatkan sebanyak 11 jenis bakteri teridentifikasi dari spesimen pus, didapatkan hasil bahwa Staphylococcus aureus dan Eschericia coli mendominasi bakteri terbanyak.
Coronary Heart Disease: Diagnosis and Therapy Iin Novita Nurhidayati Mahmuda; Nanda Nurkusumasari; Fakhri Nofaldi; Prihatin Puji Astuti; Ferika Dian Syafitri; Dessy Dessy
Solo Journal of Anesthesi, Pain and Critical Care (SOJA) Vol 1, No 2 (2021): October 2021
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (823.02 KB) | DOI: 10.20961/soja.v1i2.55191

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Coronary heart disease (CHD), is one of the non-communicable diseases that has a tendency to increase every year and have an impact not only on developed countries, but also in developing countries. According to the World Health Organization (WHO), in 2012 there were 56 million deaths worldwide caused by non-communicable disease and heart disease contributed 46.2% or caused 17.5 million deaths. This review article to give brief explanation about CHD from risk factors, diagnosed criteria, management therapy and prognosis. Risk factors for CHD can be distinguished into major risk factors and minor risk factors. Symptoms of CHD are discomfort in the chest ranging from pain crushed during activity and improved with rest to continuous chest pain. The diagnosis of CHD is established based on anamnesis, physical examination, and laboratory examination. The CHD classification consists  of Stable Angina Pectoris (APS) and Acute Coronary Syndrome (ACS). Lifestyle changes accompanied by right medication can reduce complications caused             by CHD.
SKRINING DAN EDUKASI ANEMIA PADA SISWI SMP MUHAMMADIYAH 7 PROGRAM UNGGULAN COLOMADU KARANGANYAR Rochmadina Suci Bestari; Riandini Aisyah; Busyra; Iin Novita Nurhidayati Mahmuda; Sulistyani; Aulida Azkia Kamila; Arum Dyah Ripdianti; Wulan Kadarsih
Jurnal Pengabdian Masyarakat Medika Vol 6. No. 1, Maret 2026
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v6i1.12734

Abstract

ABSTRAK Kesehatan remaja merupakan isu publik yang signifikan secara global dan di Indonesia. Faktor-faktor seperti kebiasaan gaya hidup dan kurangnya pengetahuan berkontribusi terhadap masalah ini, termasuk anemia. Anemia masih menjadi masalah kesehatan masyarakat yang penting di Indonesia, dengan prevalensi tinggi pada remaja putri. Kegiatan ini bertujuan untuk skrining anemia dan memberi edukasi tentang anemia pada siswi SMP Muhammadiyah 7 Program Unggulan Colomadu. Kegiatan ini dilaksanakan pada 19 Februari 2025, melibatkan 22 siswi kelas 7, 8, dan 9 di SMP Muhammadiyah 7 Program Unggulan Colomadu. Metode yang digunakan adalah skrining Hb dan edukasi tentang anemia, termasuk pengisian kuesioner pengetahuan. Hasil skrining menunjukkan 9,09% siswi menderita anemia. Rata-rata skor pengetahuan adalah 10,5. Analisis uji-t independen menunjukkan bahwa tidak ada perbedaan yang signifikan secara statistik antara skor pengetahuan siswi yang anemia dan yang tidak anemia (p = 0,917). Hal ini menyimpulkan bahwa pengetahuan bukan satu-satunya faktor penentu status anemia, karena faktor lain seperti nutrisi dan pola makan juga berperan dalam kondisi anemia. ABSTRACT Adolescent health is a significant public issue globally and in Indonesia. Factors such as lifestyle habits and lack of knowledge contribute to this problem, including anemia. Anemia remains an important public health issue in Indonesia, with a high prevalence among adolescent girls. This activity aims to screen for anemia and provide education about anemia to female students at SMP Muhammadiyah 7 Program Unggulan Colomadu. This activity was conducted on February 19, 2025, involving 22 female students in grades 7, 8, and 9 at SMP Muhammadiyah 7 Program Unggulan Colomadu. The methods used were Hb screening and education about anemia, including filling out a knowledge questionnaire. The screening results showed that 9.09% of female students suffered from anemia. The average knowledge score was 10.5. Independent t-test analysis showed that there was no statistically significant difference between the knowledge scores of students with anemia and those without anemia (p = 0.917). This concludes that knowledge is not the only determining factor for anemia status, as other factors such as nutrition and diet also play a role on anemia condition.
High Mortality Among Clinically Pneumocytis Pneumonia Infection in Low CD4 HIV Patients: Case Series Iin Novita Nurhidayati Mahmuda; Dhani Redhono Harioputro; R. Satriyo Budhi Susilo; Tatar Sumandjar; Arifin Arifin
Biomedika Vol 16, No 1 (2024): Biomedika Februari 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v16i1.3823

Abstract

Objective: The number of HIV cases in Indonesia reached a peak in 2019 with 50,282 cases dispersed over 407 of 507 districts and cities (or 80%) of the country's provinces. Central Java is the province after DKI Jakarta and East Java which has a mortality of 12.41 and an HIV/AIDS prevalence of 22% of all cases. High mortality in HIV patients influenced by very low CD4 count ≤ 50 cells/mm3. Identification of clinical characteristics, risk factors and causes of death is very important to carry out optimal management of HIV/AIDS for delaying the progression of infection and saving lives. Design and method: We identified three patients with newly diagnosed HIV between January to April, 2023. We provide demographic data, clinical characteristics, laboratory examination, chest x-ray imaging and final outcome. Results: We presented 3 newly diagnosed HIV patients. They are still young < 40 years old, the majority have BMI < 18.5. Major opportunistic infections are oral candidiasis (100%), Pruritic Popular Eruption (PPE), pulmonary infection due to Tuberculosis, Pneumocystis pneumonia (PCP) and bacterial pneumonia. Hematological alteration dominated by anemia. Increased of transaminase enzyme and hyponatremia are also common. All patients had CD4 count < 20 cells/mm3, only one patient survived. Causes of death were pulmonary infection mainly due to clinical PCP. Conclusion: PCP is one of the fatal opportunistic infections in HIV. It is necessary to be diagnosed as early as possible so that patients can start Anti-Retro Viral (ARV) at an early stage to improve prognosis.
Co-Authors Adhalia, Lian Aditya Putra Perdana Affifah, Fathiyya Noor Akbar Wardhana Andri Sugeng Prasetyo Angiesta Pinakesty Anis Nuristiqomah Aqmarina, Nadia Wdihi Arifin Arifin Arum Dyah Ripdianti Aulida Azkia Kamila Azahra Khansa Muza Azarine Marwah Bahrodin, Bahrodin Busyra, Busyra Cahyo, Febrian Dwi Citra Saputra, Rada Dahlia Winda Nurarifah Denny Bimatama Pradita Dessy Dessy Desty Triza Pratiwi Devi Usdiana Rosyidah Devi Usdiana Rosyidah Doni Priambodo Dwi, Raafika Studiviani Em Sutrisna Erika Diana Risanti Fairuz Ulfah Faizah, Ishmah Nur Fakhri Nofaldi Fathiyya Noor Afifah Fauziah, Nida Faradisa Febrian, Rizky Ferika Dian Syafitri Flora Ramona Sigit Prakoeswa Fuad Gandhi Torizal Harioputro, Dhani Redhono Herdiana, Nandya Ilhami, Afiq Zakie Indriyati Oktoviano R Ishmah Nur Faizah Iwan Setiawan Izzati, Sofi Filda Jati, Izzah Tsaqoofah Juwita, Triana Rahma Kania, Yulia Intan Khairunnisa, Reza Khotik, Laisa Kurnia Retnowati Kurnia Retnowati, Kurnia Lian Adhalia Listiana Masyita Dewi Maharotullaili Nur Azizah Marhamah, Nisrinah Maryati Maslahah, Syah Fillia Nurul Maulana, Yudrik Maya Monica Manurung Metana Puspitasari Mubaraq, Syahrun El Muhammad Adnan Nadia Wdihi Aqmarina Nanda Dhea Ayu Sawitri Nanda Dhea Ayu Sawitri Nanda Nurkusumasari Nandya Herdiana Naruma, Anteng Nining Lestari Nisa, Faridita Khoirun Nor Hilyati Nugrahaeni, Sarwasri Fajra Nugraheni, Frida Asfarina Oktafiani, Niken Sari Oktoviano R, Indriyati Olivia Bunga Putri Pinakesty, Angiesta Poetrie Wulandari Ruswandi Prasetyo, Andri Sugeng Prihatin Puji Astuti Priscillah, Wildan Putra, Catur Permana Putriyantiwi, Idoviari R. Satriyo Budhi Susilo Raafika Studiviani Dwi Binuko Rada Citra Saputra Rajendra, Hafish Harfian Raniah, Siti Fairuz Ratnasari Bondan Wijayanti Rezki, Yuniana Nur Riandini Aisyah Rochmadina Suci Bestari Roro Flaviana Bayu Adistyani Roro Flaviana Bayu Astiyani Ruswandi, Poetrie Wulandari Safari Wahyu Jatmiko Sahilah Ermawati Sahilah Ernawati Santi, Tika Melandya Sifak, Sheila Faadhila Siti Soekiswati Sri Wahyu Basuki Sri Wahyuni Srirojanakul, Sirada Subekti, Tyas Hanurita Sulistyani Sulistyani , Sulistyani Sulistyani Sulistyani Sulistyani Sulistyani Sutanto, Bambang Syah, Devan Adil Taroeno, Suryo Aribowo Tatar Sumandjar Tri Agustina, Tri Triana Rahma Juwita Tyas Hanurita Subekti Utami, Musrifah Budi Vitania Marsya Wibowo, Muhammad Irfan Sulystyo Wildan Priscillah Wulan Kadarsih Yaasiin, Putri Isa Maharani Yamsun, Rahmat Dani Yudrik Maulana Yulia Intan Kania Yuniana Nur Rezki Zelindrah, Virgil