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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Indonesian Journal of Tropical and Infectious Disease Biomedika Herb-Medicine Journal Indonesian Journal of Medicine MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan JURNAL PENDIDIKAN TAMBUSAI JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Ilmiah Kesehatan Indonesian Journal for Health Sciences (IJHS) Health Information : Jurnal Penelitian Solo Journal of Anesthesi, Pain and Critical Care KESANS : International Journal of Health and Science Journal of Innovation Research and Knowledge Proceeding ISETH (International Summit on Science, Technology, and Humanity) Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika International Journal of Health Science and Technology JHeS (Journal of Health Studies) Jurnal Keperawatan Biomedika Cermin Dunia Kedokteran
Iin Novita Nurhidayati Mahmuda
Universitas Muhammadiyah Surakarta
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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CEPHALIC TETANUS A RARE LOCAL TETANUS Iin Novita Nurhidayati Mahmuda; Doni Priambodo
Biomedika Vol 7, No 2 (2015): Biomedika Agustus 2015
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v7i2.1872

Abstract

Woman, 68 years old came to hospital with chief complain trismus and dysphagia. She was in a good condition with physical examination and standard laboratory test reveal normal value. The neurologist found multiple parese of cranial nerve (V, VII, IX, X, XI). After further examination include electromedic test and head ct scan with contrast the neurologist did not find any abnormality that may explain her symptoms. The patient then consulted to the internist with suspect of local tetanus infection because of focal infection in her dental caries. The patient is then treated with antibiotics, convultion inhibitor agent, also given tetanus immunoglobulin. During the treatment, her symptoms improved. There were no other severe complication. Patient was returning home on the ninth day of hospitalisation and ready for her dentist appointment.Keywords : Trismus, dysphagia, parese, tetanus, tetanus imunoglobulin
PENCEGAHAN DAN TATALAKSANA DEKUBITUS PADA GERIATRI Iin Novita Nurhidayati Mahmuda
Biomedika Vol 11, No 1 (2019): Biomedika Februari 2019
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v11i1.5966

Abstract

Decubitus ulcer or pressure sore is a serious morbidity in elderly patients. The incidence of pressure sores in geriatric patients is 11%. Population at 70-75 of their aged had a two-fold risk higher for suffering decubitus ulcers compared with 55-69 years of aged people. The highest incidence is in group of 80-84 years old peole. Studies has found 95% of cases are preventable. Prevention efforts have already proven to be more effective and cost effective than treatment. Prevention efforts include mobilization, skin care, fulfillment of fluids and adequate nutrition, the use of tools / aids for body movement, environmental regulation of health care and education. Treatment of decubitus ulcers by administering topical material, systemic drugs or surgery should be done as early as possible. Keyword: decubitus ulcer, geriatric patients, prevention, treatment 
HIPERGLIKEMIA SEBAGAI PREDIKTOR KEBERHASILAN PENGOBATAN PASIEN DENGAN SINDROM KORONER AKUT DI RSUD X SURAKARTA Iin Novita Nurhidayati Mahmuda; Yuniana Nur Rezki; Wildan Priscillah
Biomedika Vol 10, No 2 (2018): Biomedika Agustus 2018
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v10i2.7023

Abstract

ABSTRAK Sindrom Koroner Akut atau acute coronary syndrome (ACS) dengan hiperglikemia pada saat masuk memiliki rerata mortalitas yang lebih tinggi, pada penelitian terbaru. Hiperglikemia pada pasien dengan ACS digambarkan sebagai respon akut dari keadaan hiperadrenergik dengan peningkatan risiko trombosis, sehingga bisa memperburuk kondisi pasien ACS selama dirawat di rumah sakit. Tujuan penelitian ini untuk mengetahui perbedaan lama tinggal dan mortalitas pada pasien ACS dengan stres hiperglikemia dan tanpa hiperglikemia stres. Jenis penelitian ini adalah penelitian observasional  analitik dengan pendekatan cross sectional. Subjek penelitian adalah pasien ACS non-diabetes di RSUD X Surakarta. Data diperoleh dari rekam medis dengan teknik purposive sampling, dianalisis dengan uji Mann-Whitney. Subjek penelitian sebanyak 68 pasien, 34 pasien ACS dengan hiperglikemia dan 34 pasien ACS tanpa hiperglikemia. Hasil penelitian ini menyatakan ada perbedaan durasi lama tinggal pasien ACS dengan dan tanpa hiperglikemia(p = 0,002) dan tidak ada perbedaan rerata mortalitas diantara keduanya.Kata kunci: Sindrom Koroner Akut, Hiperglikemia, Lama Rawat Inap, Mortalitas ABSTRACT Acute Coronary Syndrome (ACS) in recent studies has been associated with hyperglycemia at the time of admission with higher mortality rates. Hyperglycemia in patients with ACS described as an acute response from a hyperadrenergic state with an increased risk of thrombosis, so it could worsen the condition of the patient ACS during the hospital stay. Aims of this study are to know differences in length of stay and mortality in ACS patients with hyperglycemia stress and without hyperglycaemia stress. This was an analytical observational research design with  cross sectional approach. The subjects were non diabetic ACS patient in RSUD X Surakarta. Data were obtained from medical record with purposive sampling technique, analyzed by Mann-Whitney test. Subjects were 68 patients, 34 patients ACS with hyperglycemia and 34 patients ACS without hyperglycemia. There is a difference in duration long of stay ACS patients with and without hyperglycemia (p = 0.002) and there is no difference in mortality.Keywords: Acute Coronary Syndrome, Hyperglycemia, Length Of Hospitalization, Mortality
FAKTOR-FAKTOR YANG MEMPENGARUHI JUMLAH CD4 PASIEN HIV AIDS YANG DITERAPI ANTIRETROVIRAL: STUDI LITERATUR Iin Novita Nurhidayati Mahmuda; Nandya Herdiana; Angiesta Pinakesty; Poetrie Wulandari Ruswandi; Triana Rahma Juwita
Prosiding University Research Colloquium Proceeding of The 13th University Research Colloquium 2021: Kesehatan dan MIPA
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.933 KB)

Abstract

Salah satu cara untuk menurunkan angka kesakitan, angka kematian, membatasi penularan serta penyebaran penyakit, dan mengurangi dampak negatif yang ditimbulkan HIV/AIDS adalah dengan terapi antiretroviral, yang salah satu keberhasilannya dinilai dari perbaikan imunologis dan diketahui bahwa cluster of differentiation 4 (CD4) sebagai penanda status kesehatan sistem imun, maka pemeriksaan CD4 dapat digunakan untuk menentukan pasien yang memerlukan pengobatan profilaksis infeksi oportunistik (IO) dan terapi antiretroviral. Untuk mengetahui faktor-faktor yang mempengaruhi jumlah CD4 pada pasien HIV/AIDS yang diterapi antiretroviral. Penelitian ini menggunakan desain penelitian literature review atau kajian literatur. Sumber penelitian diambil dari beberapa database dengan kata kunci “("increase CD4" AND "decrease CD4" AND "hiv" OR "human immunodeficiency virus" AND "acquired immunodeficiency syndrome" AND "antiretroviral")”. Dari 612 artikel, terdapat 8 artikel yang sesuai dengan kriteria retriksi. Dari beberapa artikel tersebut didapatkan faktor-faktor yang mempengaruhi angka CD4 adalah jenis kelamin, usia, stadium klinis, jumlah CD4 awal, kepatuhan dalam terapi antiretroviral (yang dipengaruhi oleh beberapa faktor, seperti dukungan sosial, tingkat pendidikan, penggunaan ponsel, jenis kelamin, waktu kunjungan ke tempat pelayanan kesehatan, faktor ekonomi), jumlah viral load, ada tidaknya koinfeksi tuberkulosis (TB), dan infeksi hepatitis C (HCV). Faktor yang mempengaruhi jumlah CD4 pada pasien HIV/AIDS yang diterapi antiretroviral adalah jenis kelamin,, usia, stadium klinis, kepatuhan pasien dalam terapi antiretroviral, jumlah CD4 awal, jumlah viral load, dan ada tidaknya infeksi oportunistik (TB, HCV).
Obesitas Sebagai Faktor Risiko Keparahan Pada COVID-19 Nadia Wdihi Aqmarina; Erika Diana Risanti; Iin Novita Nurhidayati Mahmudah; Safari Wahyu Jatmiko
Prosiding University Research Colloquium Proceeding of The 13th University Research Colloquium 2021: Kesehatan dan MIPA
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (362.939 KB)

Abstract

Obesitas diketahui sebagai peradangan kronis derajat rendah. Hal ini menjadi faktor yang dapat menyebabkan keparahan pada gejala COVID-19. Gejala COVID-19 dinyatakan dalam asimptomatis hingga kritis dan obesitas dicurigai memiliki peran dalam tingkat keparahan COVID-19. Tujuan penelitian ini adalah untuk mengetahui hubungan antara obesitas dengan tingkat keparahan COVID-19. Penelitian ini dilakukan pada 13 Desember 2020 pada mesin pencarian Pubmed, Science Direct dan Google Scholar dengan memasukkan kata kunci (obesity OR overweight) AND risk factor AND (severe OR severity) AND fatality rate AND (COVID-19 OR SARS-CoV-2 OR Novel coronavirus). Selanjutnya dilakukan skrining sesuai dengan kriteria restriksi yang telah ditetapkan dan mengelompokkan artikel penelitian dalam tabel lalu diurutkan sesuai alphabet nama peneliti. Data yang sudah terkumpul selanjutnya dilakukan penarikan kesimpulan, sehingga didapatkan sampel sebanyak 11 artikel berasal dari Negara Italia, China, New York, USA dan Prancis. Berdasarkan hasil penelitian didapatkan adanya hubungan antara BMI dan nilai risiko yang menyebabkan keparahan pada COVID-19. Semakin tinggi kenaikan angka BMI akan memberikan nilai risiko yang lebih tinggi pula. Keparahan penyakit ditandai dengan penggunaan alat bantu pernafasan (IMV, NIV, oksigenasi dan ECMO), penggunaan ruang ICU, penurunan PaO2 dan SaO2 serta hipoksemia.
HUBUNGAN KADAR VITAMIN D DAN PENURUNAN KADAR GLUKOSA DARAH PENDERITA DIABETES MELLITUS Ratnasari Bondan Wijayanti; Iin Novita; Riandini Aisyah; Erika Diana Risanti
Prosiding University Research Colloquium Proceeding of The 13th University Research Colloquium 2021: Kesehatan dan MIPA
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (528.708 KB)

Abstract

Diabetes melitus atau disebut Diabetes merupakan penyakit gangguan metabolik akibat pankreas tidak memproduksi cukup insulin atau tubuh tidak dapat menggunakan secara efektif insulin yang diproduksi. Kelebihan sekresi glukagon oleh sel alfa dan insulin yang tidak dapat diproduksi atau tidak berperan secara efektif oleh sel beta menyebabkan peningkatan kadar glukosa dalam darah (hiperglikemia). Pemberian vitamin D meningkatkan transkripsi gen reseptor insulin untuk mengurangi kenaikan hiperglikemik dengan menginduksi sel β pankreas. Tujuan: Menganalisis peran vitamin D dalam menurunkan kadar glukosa darah penderita Diabetes melitus. Metode: Penelitian ini menggunakan jenis studi literatur review dengan menggunakan sumber artikel terbitan dari tahun 2015 sampai November 2020 pada database PubMed dan Science Direct dengan menggunakan kata kunci "vitamin d" OR "ergocalciferols" OR vitamin D AND "glucose" AND "Diabetes mellitus". Analisis data berupa kalimat naratif yang dimulai dengan pemilihan artikel yang sesuai kriteria inklusi, kriteria eksklusi dan relevansi penelitian, yang selanjutnya dilakukan penarikan kesimpulan. Hasil: Artikel yang direview sebanyak 7 artikel yang berasal dari negara-negara seperti Mesir, Pakistan, Arab Saudi, Iran dan Taiwan. Uji klinis pada beberapa penelitian menunjukkan hasil bahwa vitamin D berperan dalam menurunkan glukosa darah pada pasien dengan penyakit diabetes yang secara signifikan menurunkan HbA1c. Kesimpulan: Vitamin D berperan dalam menurunkan kadar glukosa darah penderita Diabetes melitus.
Correlation Cholesterol and Triglyceride Level on Cognitive Function in Type 2 Diabetes Mellitus Iin novita Nurhidayati Mahmuda; Fairuz Ulfah
International Journal of Health Science and Technology Vol 2, No 3 (2021): April
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (600.865 KB) | DOI: 10.31101/ijhst.v2i3.1913

Abstract

Diabetes Mellitus (DM) is a type of non-communicable disease that is still a public health problem both globally, regionally, nationally and locally. The prevalence of DM in the world is 1.9% and makes DM the seventh cause of death in the world. One of the complications caused by DM is a decrease in cognitive function. The triggers for cognitive function include high cholesterol and triglyceride levels. The purpose of this study was to determine the correlation between cholesterol and triglyceride leves on cognitive function in Type 2 Diabetes Mellitus at Boyolali. This study is an analytic observational study with a cross sectional approach .The subject are 51 respondents. The sampling technique used in this study was  purposive sampling technique. Data analyzed with chi-square test . it was found that there was a correlation between cholesterol level and cognitive function with a p-value of 0.003 0.05 and there was also correlation triglyceride level and cognitive function with a p-value of 0.000 0.05.  There is a significant correlation between cholesterol and triglyseride level with cognitive function in type II diabetic patient. 
Potential Anti-Bacterial Extract of Red Belt (Piper Crocatum Ruiz & Pav.) Against Staphylococcus Epidermidis Nanda Dhea Ayu Sawitri; Iin Novita Nurhidayati Mahmuda
Jurnal KESANS : Kesehatan dan Sains Vol 1 No 11 (2022): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v1i11.102

Abstract

Introduction: Red betel leaf is a plant native to Indonesia which is used as an antiseptic, anti-cancer, and infection treatment. The ethanol content of red betel leaf extract is known to have antibacterial activity. Among them there are alkaloids, flavonoids, essential oils, tannins, and saponins. Objective: to determine the potential of red betel leaf extract (Piper crocatum Ruiz & Pav.) in inhibiting the growth of Staphylococcus epidermidis bacteria. Methods: Staphylococcus epidermidis bacteria were divided into 5 groups, PEG 5% as negative control, clindamycin 30µg/disk as positive control, extract 20%, 40%, 80% as treatment group. Measuring the zone of inhibition using a ruler. Result and Discussion: Staphylococcus epidermidis inhibition zone was formed at concentrations of 20%, 40%, 80%. Kruskal Wallis analysis showed significant results of p = 0.000 for bacteria. Conclusion: Red betel leaf extract (Piper crocatum Ruiz & Pav.) has significant antibacterial activity against Staphylococcus epidermidis. The higher the concentration, the larger the diameter of the inhibition zone.
Potential Ekstract Of Red Betel Leaf (Piper crocatum Ruiz & Pav.) as a Natural Hand Sanitizer Maya Monica Manurung; Tyas Hanurita Subekti; Nanda Dhea Ayu Sawitri; Iin Novita Nurhidayati Mahmuda
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 10, No 2 (2023): August
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.10.2.2023.141-149

Abstract

Background: Hands are the most common medium for spreading disease. Red betel leaf has antibacterial bioactive compounds such as flavonoids, alkaloids, polyphenols, tannins, and essential oils. The most common way to clean hands is to use hand sanitizer.Objective: To determine the antibacterial potential of red betel leaf extract (Piper crocatum Ruiz & Pav.) against the growth of Staphylococcus aureus, Streptococcus pyogenes, and Salmonella typhi as an active ingredient in hand sanitizers. Methods: Each bacterium, namely Staphylococus aureus, Streptococcus pyogenes and Salmonella typhi were divided into 6 groups, PEG 5% as a negative control, clindamycin for Staphylococus aureus and Streptococcus pyogenes and chloramphenicol for Salmonella typhi as a positive control, 70% alcohol as a comparison for hand sanitizer, extract 20%, 40%, and 80% as treatment groups. The obstacle zone is measured using a ruler.Results: Zones of inhibition against Staphylococus aureus, Streptococcus pyogenes, and Salmonella typhi were formed at concentrations of 20%, 40%, and 80%. Kruskal Wallis statistical analysis showed significant results with p=0.000.Conclusion: Red betel leaf extract has statistically significant antibacterial activity against Staphylococcus aureus, Streptococcus pyogenes and Salmonella typhi. The extract concentration of 40% is the optimal concentration as a raw material for hand sanitizer.
The Relationship Between Body Mass Index and Blood Sugar with Cognitive Function in Patients with Diabetes Mellitus Azahra Khansa Muza; Sulistyani Sulistyani; Siti Soekiswati; Iin Novita Nurhidayati Mahmuda
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 6, No 1 (2023): Herb-Medicine Journal April 2023
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v6i1.16913

Abstract

Impaired cognitive function is an individual's inability to perform daily functions and limits the quality of life. The prevalence of cognitive dysfunction in people in China, Spain, America, and Canada is 12.6%, 22.2%, and 16.8%. The prevalence of cognitive impairment that often occurs in Indonesia, namely dementia, is 10%. Insulin resistance causes inflammation and mitochondrial dysfunction. The state of hyperglycemia occurs activation of pro-inflammatory cytokines that cause cognitive impairment. This study aims to determine the relationship between body mass index and blood glucose on cognitive function in patients with diabetes mellitus at the Gatak Sukoharjo Health Center, consisting of 36 patients. Research using observational analytics with Pearson test. The sample selection technique is purposive sampling. Based on the results of the study with the Pearson test (p = 0.043), it means that there is a significant relationship. Furthermore, obtained (p = 0.578) means that there is no significant relationship. The conclusion of the study is that there is a relationship between body mass index and cognitive function, but there is no relationship between transient blood sugar and cognitive function in patients with diabetes mellitus.
Co-Authors Adhalia, Lian Aditya Putra Perdana Affifah, Fathiyya Noor Afifah, Fathiyya Noor Akbar Wardhana Angiesta Pinakesty Aqmarina, Nadia Wdihi Arifin , Arifin Astuti, Prihatin Puji Azahra Khansa Muza Azarine Marwah Bahrodin, Bahrodin Busyra Cahyo, Febrian Dwi Citra Saputra, Rada Dessy, Dessy Devi Usdiana Rosyidah Doni Priambodo Dwi, Raafika Studiviani Em Sutrisna Erika Diana Risanti Fairuz Ulfah Faizah, Ishmah Nur Fauziah, Nida Faradisa Febrian, Rizky Flora Ramona Sigit Prakoeswa Fuad Gandhi Torizal Harioputro , Dhani Redhono Herdiana, Nandya Ilhami, Afiq Zakie Indriyati Oktoviano R Iwan Setiawan Izzati, Sofi Filda Jati, Izzah Tsaqoofah Juwita, Triana Rahma Kadarsih, Wulan Kamila, Aulida Azkia Kania, Yulia Intan Khairunnisa, Reza Khotik, Laisa Kurnia Retnowati Kurnia Retnowati, Kurnia Lian Adhalia Listiana Masyita Dewi Maharotullaili Nur Azizah Marhamah, Nisrinah Marsya, Vitania Maryati Maslahah, Syah Fillia Nurul Maulana, Yudrik Maya Monica Manurung Metana Puspitasari Mubaraq, Syahrun El Nadia Wdihi Aqmarina Nanda Dhea Ayu Sawitri Nanda Dhea Ayu Sawitri Nandya Herdiana Naruma, Anteng Nining Lestari Nisa, Faridita Khoirun Nofaldi, Fakhri Nugrahaeni, Sarwasri Fajra Nugraheni, Frida Asfarina Nurkusumasari, Nanda Oktafiani, Niken Sari Oktoviano R, Indriyati Pinakesty, Angiesta Poetrie Wulandari Ruswandi Prasetyo, Andri Sugeng Priscillah, Wildan Putra, Catur Permana Putriyantiwi, Idoviari Raafika Studiviani Dwi Binuko Rajendra, Hafish Harfian Raniah, Siti Fairuz Ratnasari Bondan Wijayanti Rezki, Yuniana Nur Riandini Aisyah Ripdianti, Arum Dyah Rochmadina Suci Bestari Ruswandi, Poetrie Wulandari Safari Wahyu Jatmiko Sahilah Ermawati Santi, Tika Melandya Sifak, Sheila Faadhila Siti Soekiswati Sri Wahyu Basuki Sri Wahyuni Srirojanakul, Sirada Subekti, Tyas Hanurita Sulistyani Sulistyani , Sulistyani Sulistyani Sulistyani Sumandjar , Tatar Susilo , R. Satriyo Budhi Susilo, R. Satriyo Budhi Sutanto, Bambang Syafitri, Ferika Dian Syah, Devan Adil Taroeno, Suryo Aribowo Tri Agustina, Tri Triana Rahma Juwita Tyas Hanurita Subekti Utami, Musrifah Budi Wibowo, Muhammad Irfan Sulystyo Wildan Priscillah Yaasiin, Putri Isa Maharani Yamsun, Rahmat Dani Yudrik Maulana Yuniana Nur Rezki Zelindrah, Virgil