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Potential Ekstract Of Red Betel Leaf (Piper crocatum Ruiz & Pav.) as a Natural Hand Sanitizer Maya Monica Manurung; Tyas Hanurita Subekti; Nanda Dhea Ayu Sawitri; Iin Novita Nurhidayati Mahmuda
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 10, No 2 (2023): August
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.10.2.2023.141-149

Abstract

Background: Hands are the most common medium for spreading disease. Red betel leaf has antibacterial bioactive compounds such as flavonoids, alkaloids, polyphenols, tannins, and essential oils. The most common way to clean hands is to use hand sanitizer.Objective: To determine the antibacterial potential of red betel leaf extract (Piper crocatum Ruiz & Pav.) against the growth of Staphylococcus aureus, Streptococcus pyogenes, and Salmonella typhi as an active ingredient in hand sanitizers. Methods: Each bacterium, namely Staphylococus aureus, Streptococcus pyogenes and Salmonella typhi were divided into 6 groups, PEG 5% as a negative control, clindamycin for Staphylococus aureus and Streptococcus pyogenes and chloramphenicol for Salmonella typhi as a positive control, 70% alcohol as a comparison for hand sanitizer, extract 20%, 40%, and 80% as treatment groups. The obstacle zone is measured using a ruler.Results: Zones of inhibition against Staphylococus aureus, Streptococcus pyogenes, and Salmonella typhi were formed at concentrations of 20%, 40%, and 80%. Kruskal Wallis statistical analysis showed significant results with p=0.000.Conclusion: Red betel leaf extract has statistically significant antibacterial activity against Staphylococcus aureus, Streptococcus pyogenes and Salmonella typhi. The extract concentration of 40% is the optimal concentration as a raw material for hand sanitizer.
The Relationship Between Body Mass Index and Blood Sugar with Cognitive Function in Patients with Diabetes Mellitus Azahra Khansa Muza; Sulistyani Sulistyani; Siti Soekiswati; Iin Novita Nurhidayati Mahmuda
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 6, No 1 (2023): Herb-Medicine Journal April 2023
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v6i1.16913

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Impaired cognitive function is an individual's inability to perform daily functions and limits the quality of life. The prevalence of cognitive dysfunction in people in China, Spain, America, and Canada is 12.6%, 22.2%, and 16.8%. The prevalence of cognitive impairment that often occurs in Indonesia, namely dementia, is 10%. Insulin resistance causes inflammation and mitochondrial dysfunction. The state of hyperglycemia occurs activation of pro-inflammatory cytokines that cause cognitive impairment. This study aims to determine the relationship between body mass index and blood glucose on cognitive function in patients with diabetes mellitus at the Gatak Sukoharjo Health Center, consisting of 36 patients. Research using observational analytics with Pearson test. The sample selection technique is purposive sampling. Based on the results of the study with the Pearson test (p = 0.043), it means that there is a significant relationship. Furthermore, obtained (p = 0.578) means that there is no significant relationship. The conclusion of the study is that there is a relationship between body mass index and cognitive function, but there is no relationship between transient blood sugar and cognitive function in patients with diabetes mellitus.
The Difference of Clinical Characteristic COVID-19 patient with Vaccinated and Unvaccinated Marwah, Azarine; Iin Novita Nurhidayati Mahmuda
Saintika Medika Vol. 19 No. 2 (2023): December 2023
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol19.SMUMM2.29958

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Coronavirus disease or COVID-19 was first discovered in Wuhan, China and spreads through respiratory droplet transmission with various clinical characteristics that are often encountered such as fever and cough, shortness of breath, myalgia and nausea/vomiting according to the severity of COVID-19 patients. The severity of clinical characteristics in COVID-19 patients can be influenced by factors of age, comorbidities, gender, immunocompromised status, occupation (healthworkers), and vaccination status. This research is for knowing the differences in the clinical characteristics of vaccinated and unvaccinated COVID-19 patients at University of Muhammadiyah Surakarta students. This study uses an observational analytic study with a cross-sectional approach and was carried out on students at the University of Muhammadiyah Surakarta who were confirmed to have COVID-19 using a google-form questionnaire as primary data. Data were analyzed using chi-square test. The symptoms of COVID-19 such as fever, cough, common cold, myalgia, anosmia or rash did not show a significant difference. Meanwhile, the symptoms of nausea/vomiting were found in individuals who had not been vaccinated more than individuals who had been vaccinated (p = 0.002). There was no significant difference in clinical characteristics of COVID-19 patients who had been vaccinated or had not been vaccinated, except for complaint of nausea/vomiting.
Hematological alteration in HIV patients Taroeno, Suryo Aribowo; Mahmuda, Iin novita Nurhidayati; Nugrahaeni, Sarwasri Fajra; Torizal, Fuad Gandhi
JHeS (Journal of Health Studies) Vol. 8 No. 1 (2024): Maret
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.3721

Abstract

HIV is a global health problem still challenging in almost all parts of the world, including Indonesia. HIV AIDS cases in Indonesia continue to increase from year to year. HIV is characterized by a progressive decline in the immune system that contributes to the clinical progression of the disease. Hematological alterations can result from the consequences of HIV. This study aimed to determine hematologic alteration in HIV patients as a predictor of disease severity. The study design was descriptive observational with a cross-sectional approach to see hematological abnormalities in HIV patients at PKU Muhammadiyah Surakarta Hospital. This study produced data that hematological alterations found include anemia in 60% of HIV patients, with the most cases being mild anemia. A small percentage of HIV patients experience leukopenia and thrombocytopenia, which are as much as 8% and 12%. HIV-positive patients have at least one or more cytopenia. Thus, hematologic alteration can independently predict morbidity and mortality and is associated with disease progression and even death.
Clinical diagnosis of leptospirosis with negative serology: case series report Mahmuda, Iin Novita Nurhidayati; Santi, Tika Melandya
International Journal of Health Science and Technology Vol. 5 No. 2 (2023): November
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v5i2.3030

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Leptospirosis is a zoonotic disease with clinical manifestations that range from mild acute febrile illness that resolves on its own to severe, life-threatening conditions with multiple organ dysfunction. Clinical features and various diagnostic tests establish leptospirosis diagnosis, such as bacterial isolation and serological examination. Because the antibody response required for serological testing is often insufficient to detect until the second week of disease (when the immune phase begins), sensitivity, when symptoms begin, is limited. Often, patients present with obvious clinical symptoms of leptospirosis but have negative serological test results. This study aimed to determine how to establish the clinical diagnosis of leptospirosis in leptospirosis cases with negative serology test results. This study used a descriptive method with a case series research design that analyzed four series of leptospirosis cases. The result of this study is that some cases of leptospirosis have obvious symptoms, but serological examination shows negative results. This can happen because new antibodies can be detected on day 6 to day 10 of the illness and reach their peak in 3-4 weeks so that the establishment of a clinical diagnosis of leptospirosis can be established from clear clinical symptoms and other laboratory tests. Establishing the clinical diagnosis of leptospirosis with negative serology can be done with the Faine scoring system.
Hubungan Kadar Kreatinin dan Leukosit terhadap Tingkat Kematian Pasien Leptospirosis Zelindrah, Virgil; Mahmuda, Iin Novita Nurhidayati; Rosyidah, Devi Usdiana; Risanti, Erika Diana
Health Information : Jurnal Penelitian Content Digitized
Publisher : Poltekkes Kemenkes Kendari

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Abstract

Penelitian ini bertujuan untuk menyelidiki hubungan antara kadar kreatinin dan jumlah leukosit dengan tingkat kematian pada pasien leptospirosis. Metode yang digunakan yaitu penelitian Observasional analitik dengan pendekatan Cross-sectional melibatkan pengumpulan data medis pasien yang terdiagnosis dengan leptospirosis dan analisis statistik untuk mengevaluasi korelasi antara kedua faktor tersebut dengan tingkat kematian. Sampel penelitian ini merupakan pasien dewasa leptospirosis berusia > 18 tahun di RS PKU Muhammadiyah, RSUD Dr. Sayidiman Magetan, dan RSUD Kartini Karanganyar. Hasil penelitian menunjukkan Terdapat hubungan yang tidak signifikan antara kadar AL (leukosit) dengan kematian pada pasien leptospirosis. Terdapat hubungan yang tidak signifikan antara kreatinin dengan kematian pada pasien leptospirosis. Terdapat hubungan yang tidak bermakna antara kadar AL (lukosit) dan kreatinin pada pasien kematian pada pasien leptospirosis.
Presentasi Klinis dan Faktor Prediktor Mortalitas Pasien Tetanus Wibowo, Muhammad Irfan Sulystyo; Mahmuda, Iin Novita Nurhidayati; Rosyidah, Devi Usdiana; Setiawan, Iwan
Health Information : Jurnal Penelitian Content Digitized
Publisher : Poltekkes Kemenkes Kendari

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Abstract

Tetanus adalah infeksi yang menyebabkan kejang otot rahang dan leher akibat Clostridium tetani. Prevalensi tetanus tinggi di negara dengan sumber daya rendah, dengan mortalitas mencapai 20-45%. Tetanus neonatal masih menjadi masalah di negara berkembang. Identifikasi faktor prediktor mortalitas tetanus termasuk leukosit dan elektrolit, penting untuk peningkatan manajemen pasien dewasa dengan risiko kematian yang tinggi. Studi ini bertujuan untuk meneliti hubungan antara kadar leukosit dan elektrolit dengan mortalitas pasien tetanus di RS PKU Muhammadiyah Surakarta. Penelitian ini merupakan penelitian korelasi dengan desain cross sectional dengan melibatkan 37 responden (30 laki-laki 7 perempuan) yang merupakan pasien tetanus yang tercatat di rekam medis.  Rata-rata usia responden adalah 56, persentase responden meninggal 43,2% sedangkan persentasae responden membaik 51,4%, persentase responden dengan angka leukosit normal dan meninggal 17,1% sedangkan angka leukosit tidak normal 28,6%, persentase responden dengan kadar natrium normal dan meninggal sejumlah 50% sama dengan persentase responden dengan kadar natrium tidak normal yang meninggal, sementara itu responden dengan kadar kalium normal dan meninggal sejumlah 29,4% dan responden dengan kadar kalium tidak normal dan meninggal sejumlah 70,6%.
Tingkat Kepatuhan Protokol Kesehatan dan Cakupan Vaksinasi pada Mahasiswa UMS yang Terpapar Covid-19 Jati, Izzah Tsaqoofah; Nurhidayati Mahmuda, Iin Novita
Jurnal Pendidikan Tambusai Vol. 6 No. 1 (2022): 2022
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jptam.v6i1.3139

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COVID-19 merupakan pandemi yang saat ini sedang terjadi di dunia yang disebabkan oleh virus yang disebut dengan Severe-Acute-Respiratory-Syndrome Corona Virus 2 (SARS-CoV-2). Penyebaran penyakit ini melalui interaksi dengan jarak yang dekat dan disebarkan melalui media perantara droplet ketika terjadi batuk, bersin, atau berbicara. Salah satu upaya penanggulangan covid-19 yaitu menerapkan protokol kesehatan (prokes) dan melakukan vaksinasi covid-19. Tujuan: Untuk mengetahui tingkat kepatuhan protokol kesehatan dan cakupan vaksinasi pada mahasiswa UMS yang terpapar covid-19. Metode: Jenis penelitian adalah penelitian deskritif observasional dengan desain cross sectional. Teknik sampling menggunakan pengambilan sampel total. Metode pengumpulan data menggunakan kuesioner google from online. Hasil: Karakteristik responden, mayoritas berusia 20-21 tahun 35 (58,3%), jenis kelamin perempuan 46 (76,7%), tinggi badan rata-rata 161,1, berat badan rata-rata 59,15, responden yang rutin olah raga 30 (50%) dan tidak olah raga 30 (50%), mayoritas responden rutin mengkonsumsi vitamin 31 (51,7%) dan mahasiwa yang sudah pernah terkonfirmasi 60 (100%). Tingkatan kepatuhan mahasiswa terhadap protokol kesehatan kesehatan termasuk dalam kategoti disiplin 38 (63,3%). Mahasiswa yang belum vaksinasi sebanyak 40 (66,7%), dosis 1 sebanyak 13 (21,7%), dosis 2 sebanyak 7 (11,7%). Kesimpulan: Tingkat kepatuhan mahasiswa terhadap protokol kesehatan termasuk dalam kategori disiplin. Tingkat cakupan vaksinasi covid-19 dikalangan mahasiswa UMS masih tergolong rendah saat dilaksanakan penelitian ini.
KOLABORASI WEBINAR: KENALI RISIKO, GEJALA, DAN PENCEGAHAN HIPERTENSI Mahmuda, Iin Novita Nurhidayati; Maslahah, Syah Fillia Nurul; Putriyantiwi, Idoviari; Oktafiani, Niken Sari; Yamsun, Rahmat Dani; Khairunnisa, Reza; Subekti, Tyas Hanurita; Rajendra, Hafish Harfian
Jurnal Pengabdian Masyarakat Medika Vol 2. No. 2, September 2022
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.322 KB) | DOI: 10.23917/jpmmedika.v2i2.482

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ABSTRAK Hipertensi adalah penyakit kronis yang masih menjadi faktor risiko utama stroke dan penyakit jantung koroner yang merupakan dua penyebab kematian utama di Indonesia. Strategi untuk menekan angka kesakitan dan komplikasi penyakit akibat hipertensi adalah pencegahan primer yaitu memberikan edukasi kepada masyarakat mengenai hipertensi, baik dari risiko, gejala, maupun pencegahannya. Kegiatan edukasi di era pandemi dapat dilaksanakan dengan metode webinar untuk menilai pemahaman peserta secara langsung. Kegiatan ini bertujuan untuk melihat pengaruh edukasi terhadap pengetahuan tentang risiko, gejala dan pencegahan hipertensi. Dalam pengimplementasiannya, Fakultas Kedokteran berkolaborasi dengan Fakultas Farmasi untuk memberikan edukasi tersebut. Pemberian edukasi dilaksanakan dengan metode webinar melalui media zoom cloud meeting serta materi presentasi. Keberhasilan pengabdian diukur dengan peningkatan nilai post-test. Analissis terhadap hasil post-test dengan uji statistik Wilcoxon menunjukkan bahwa nilai p < 0,05, yang berarti terdapat peningkatan pengetahuan yang signifikan. Dengan demikian dapat disimpulkan bahwa webinar merupakan salah satu media edukasi yang dapat meningkatkan pengetahuan masyarakat mengenai hipertensi.   ABSTRACT                 Hypertension is a chronic disease that is still a major risk factor for stroke and coronary heart disease, which are the two main causes of death in Indonesia. The strategy to reduce the number and impact of diseases caused by hypertension is primary prevention, namely providing education to the public about hypertension, both from the risks, symptoms, and prevention. Educational activities in the pandemic era can be carried out using the webinar method to assess participants' understanding directly. This activity aims to see the effect of education on knowledge about the risks, symptoms and prevention of hypertension. In its implementation, the Faculty of Medicine collaborates with the Faculty of Pharmacy to provide this education. Education is provided using the webinar method through zoom cloud meeting media and presentation materials. The success of achievement is measured by increasing the post-test scores. Analysis of the post-test results with the Wilcoxon statistical test showed that the p value <0.05, which means that there was a significant increase in knowledge. Thus it can be said that the webinar is one of the educational media that can increase the public knowledge about hypertension.  
SKRINING DAN TATALAKSANA KECACINGAN DAN GIZI KURANG PADA SISWA-SISWI SD MUHAMMADIYAH PROGRAM UNGGULAN KARANGANYAR Binuko, Raafika Studiviani Dwi; Mahmuda, Iin Novita Nurhidayati; Bestari, Rochmadina Suci; Agustina, Tri; Dewi, Listiana Masyita; Fauziah, Nida Faradisa; Febrian, Rizky; Syah, Devan Adil; Khotik, Laisa; Nisa, Faridita Khoirun; Naruma, Anteng
Jurnal Pengabdian Masyarakat Medika Vol 2. No. 2, September 2022
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (306.501 KB) | DOI: 10.23917/jpmmedika.v2i2.629

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ABSTRAK                 Usia sekolah dasar (SD) merupakan usia tertinggi berisiko terjadinya kecacingan. Kecacingan pada siswa SD bisa menyebabkan anemia, status gizi kurang, serta penurunan konsentrasi dan prestasi belajar. Gejala kecacingan terkadang sulit untuk dideteksi sehingga orangtua maupun guru tidak mengetahui ada kecacingan pada siswa. Penyakit ini dapat didiagnosis dengan pemeriksaan laboratorium sederhana, sebagai skrining. Penyakit kecacingan dan gizi kurang bisa dipengaruhi oleh berbagai hal, salah satunya adalah pengetahuan siswa, orangtua dan guru yang kurang tentang kecacingan dan status gizi. Kegiatan ini bertujuan untuk mendeteksi kecacingan dan gizi kurang pada siswa SD. Metode yang digunakan adalah pemeriksaan feses langsung dan pengukuran status gizi. Hasil pengukuran status gizi dari total 111 siswa didapatkan 19 (17%) siswa dengan IMT kurus dan 10 siswa (9%) dengan IMT sangat kurus. Sedangkan pemeriksaan sampel feses dari 8 siswa tidak ditemukan tanda-tanda kecacingan. Tingkat pengetahuan guru tentang gizi dan kecacingan sudah sangat baik, sedangkan untuk siswa dan wali murid setelah dilakukan penyuluhan terdapat peningkatan pengetahuan.   ABSTRACT Group age of elementary school is the highest group age for the risk of helminthiasis. Worms in elementary school students may cause anemia, poor nutritional status, and decreased concentration and learning achievement. Symptoms of helminthiasis are sometimes difficult to detect so that parents and teachers do not know that about this. This disease can be diagnosed by simple laboratory tests, as a screening. Helminthiasis and malnutrition can be influenced by various things, one of which is the lack of knowledge of students, parents and teachers about helminthiasis and nutritional status. This activity aims to detect worms and malnutrition in elementary school students. The method used is direct stool examination and measurement of nutritional status. The results of measuring the nutritional status of a total of 111 students obtained 19 (17%) students with a thin BMI and 10 students (9%) with a very thin BMI. Meanwhile, examination of feces samples from 8 students found no signs of worms. The level of knowledge of teachers about nutrition and helminthiasis is very good, while for students and guardians after counseling there is an increase in knowledge.
Co-Authors Adhalia, Lian Aditya Putra Perdana Affifah, Fathiyya Noor Akbar Wardhana Angiesta Pinakesty Aqmarina, Nadia Wdihi Arifin , Arifin Azahra Khansa Muza Bahrodin, Bahrodin Bambang Sutanto Binuko, Raafika Studiviani Dwi Citra Saputra, Rada Dessy Dessy Devi Usdiana Rosyidah Doni Priambodo Dwi, Raafika Studiviani Em Sutrisna Erika Diana Risanti Fairuz Ulfah Faizah, Ishmah Nur Fakhri Nofaldi Fauziah, Nida Faradisa Febrian Dwi Cahyo Febrian, Rizky Ferika Dian Syafitri Fuad Gandhi Torizal Harioputro , Dhani Redhono Herdiana, Nandya Ilhami, Afiq Zakie Indriyati Oktoviano R Iwan Setiawan Izzati, Sofi Filda Jati, Izzah Tsaqoofah Juwita, Triana Rahma Kania, Yulia Intan Khairunnisa, Reza Khotik, Laisa Kurnia Retnowati Kurnia Retnowati, Kurnia Lestari, Nining Lian Adhalia Listiana Masyita Dewi Maharotullaili Nur Azizah Marhamah, Nisrinah Marsya, Vitania Marwah, Azarine Maryati Maslahah, Syah Fillia Nurul Maulana, Yudrik Maya Monica Manurung Metana Puspitasari Mubaraq, Syahrun El Nadia Wdihi Aqmarina Nanda Dhea Ayu Sawitri Nanda Dhea Ayu Sawitri Nanda Nurkusumasari Nandya Herdiana Naruma, Anteng Nisa, Faridita Khoirun Nugrahaeni, Sarwasri Fajra Nugraheni, Frida Asfarina Oktafiani, Niken Sari Oktoviano R, Indriyati Pinakesty, Angiesta Poetrie Wulandari Ruswandi Prasetyo, Andri Sugeng Prihatin Puji Astuti Priscillah, Wildan Putra, Catur Permana Putriyantiwi, Idoviari Raafika Studiviani Dwi Binuko Rajendra, Hafish Harfian Ratnasari Bondan Wijayanti Rezki, Yuniana Nur Riandini Aisyah Rochmadina Suci Bestari Ruswandi, Poetrie Wulandari Safari Wahyu Jatmiko Sahilah Ermawati Santi, Tika Melandya Sifak, Sheila Faadhila Siti Soekiswati Sri Wahyu Basuki Sri Wahyuni Srirojanakul, Sirada Subekti, Tyas Hanurita Sulistyani , Sulistyani Sulistyani Sulistyani Sumandjar , Tatar Susilo , R. Satriyo Budhi Susilo, R. Satriyo Budhi Syah, Devan Adil Taroeno, Suryo Aribowo Tri Agustina, Tri Triana Rahma Juwita Tyas Hanurita Subekti Ulfah, Fairuz Utami, Musrifah Budi Wibowo, Muhammad Irfan Sulystyo Wildan Priscillah Yaasiin, Putri Isa Maharani Yamsun, Rahmat Dani Yudrik Maulana Yuniana Nur Rezki Zelindrah, Virgil