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Darmawi .
Faculty Of Engimeering, Department Of Mechanical Engineering Of Sriwijaya University
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IMPLEMENTASI PENDIDIKAN MULTIKULTURALISME PADA MASYARAKAT MINORITAS SUKU ANAK DALAM DI BUKIT DUA BELAS, AIR HITAM KABUPATEN SAROLANGUN PROVINSI JAMBI Suparno, Suparno; Darmawi, Darmawi; Anas, Marnisyah; Ansori, Ansori
Jurnal Literasiologi Vol 13 No 1 (2025): Jurnal Literasiologi
Publisher : Yayasan Literasi Kita Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47783/literasiologi.v13i1.884

Abstract

Pendidikan multikulturalisme bertujuan untuk menciptakan pemahaman yang lebih luas terhadap keberagaman budaya dan membangun sikap toleransi dalam masyarakat. Suku Anak Dalam (SAD) yang bermukim di kawasan Bukit Dua Belas, Air Hitam, Kabupaten Sarolangun, Provinsi Jambi, merupakan kelompok minoritas yang masih menghadapi berbagai tantangan dalam akses pendidikan. Penelitian ini bertujuan untuk menganalisis implementasi pendidikan multikulturalisme di komunitas SAD, mengidentifikasi faktor pendukung dan penghambatnya, serta merumuskan strategi yang dapat diterapkan untuk meningkatkan akses dan kualitas pendidikan bagi mereka. Metode penelitian yang digunakan adalah pendekatan kualitatif dengan teknik wawancara, observasi, dan studi literatur. Hasil penelitian menunjukkan bahwa implementasi pendidikan multikulturalisme di komunitas SAD masih mengalami kendala, seperti minimnya infrastruktur pendidikan, keterbatasan tenaga pendidik yang memahami budaya lokal, serta rendahnya partisipasi masyarakat dalam pendidikan. Oleh karena itu, diperlukan kebijakan pendidikan yang lebih inklusif, pelatihan bagi guru, serta pendekatan berbasis budaya untuk meningkatkan efektivitas pendidikan multikulturalisme bagi masyarakat minoritas SAD.
Karakteristik Pasien Nyeri Punggung Bawah di Poliklinik Saraf RSUD Arifin Achmad Provinsi Riau Maryanti, Yossi; Darmawi, Darmawi; Zikra, Izza Fattalia; Khairussyifa, Najmi; Arenja, Regina Trisya; Aini, Sabrina
Jurnal Ilmu Kedokteran Vol 19, No 1 (2025): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v19i1.2025.77-83

Abstract

Low back pain (LBP) is defined as discomfort felt between the lower costal margin and the inferior gluteal fold, and it is one of the most common complaints that bring people to seek medical attention. The World Health Organization (WHO) in 2017 reported that LBP ranked second as a global cause of disability in musculoskeletal system issues, and according to WHO data from 2022, 619 million people worldwide suffer from LBP. This study aims to identify the characteristics of patients with low back pain who seek treatment at the Neurology Polyclinic Arifin Achmad General Hospital of Riau Province. The characteristics examined include age, gender, work duration, body mass index (BMI), waist-hip ratio (WHR), pain severity, and disability level in daily activities. This is a descriptive observational study with a cross-sectional design, conducted at the Neurology Polyclinic Arifin Achmad General Hospital of Riau Province, from July to September 2024. Data were collected through guided interviews using structured questionnaires, the numeric rating scale (NRS), and the oswestry disability index (ODI), as well as anthropometric measurements. The frequency distribution of each characteristic was analyzed using SPSS. The sample was collected, consisting of 50 patients. The results showed that the majority of low back pain patients were aged 35-55 years (54%), female (62%), worked ≥ 8 hours per day (58%), had a BMI in the obese category (54%), had a WHR in the central obesity category (52%), experienced severe pain (52%), and had a severe disability (58%).
Treatment Of Prolapsus Bulbus Oculi In Domestic Cats Sukma, Zahwa Tamara; Darmawi, Darmawi; Sayuti, Arman; Amiruddin, Amiruddin; Syafruddin, Syafruddin; Daud, Razali; Erwin, Erwin; Panjaitan, Budianto; Ferdian, Riyan; Zamzami, Rumi Sahara; Usrina, Nora; Akmal, Muslim; Balqis, Ummu
Jurnal Medika Veterinaria Vol 19, No 1 (2025): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v19i1.37430

Abstract

Bulbus oculi prolapse is a condition characterized by the protrusion of the eyeball from the eye socket, which can be caused by various factors such as trauma, elevated intraocular pressure, and abnormalities in the eye muscles. This case study aimed to examine the treatment of bulbus oculi prolapse in domestic cats. A female calico cat named Mici presented with a chronic left eye injury that had become infected, leading to inflammation and persistent ocular discharge. The cats body weight was 0.7 kg, and its temperature was 38.2C. Surgical treatment was performed using an enucleation technique. The procedure involved an incision along the mid-anterior eyelid, extending to the lower eyelid. Dissection was carried out to expose the bulbus oculi, which was then ligated and excised. The eyelid margins were sutured using simple interrupted sutures. Postoperatively, the cat was administered antibiotics and antihistamines.
Makna Tekstual Dan Kontekstual Qs. Ar Rahman 55: 1-3 dan Qs. Al Anfaal 8: 46 Tentang Syukur dan Sabar Darmawi, Darmawi; Mawardi, Mawardi; Hidayat, Husni; Ismail, M. Syukri
Al-Muhith: Jurnal Ilmu Qur'an dan Hadits Al-Muhith Vol. 4, No. 2 (2025)
Publisher : Sekolah Tinggi Ilmu Qur'an (STIQ) Amuntai Kalimantan Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35931/am.v4i2.5037

Abstract

Makna tekstual mengacu pada interpretasi literal ayat-ayat tersebut, sementara makna kontekstual mempertimbangkan latar belakang historis dan situasional di sekitar penurunan ayat tersebut. Dalam Qs. Ar-Rahman ayat 1-3, ayat-ayat tersebut menyoroti keajaiban ciptaan Allah yang meliputi penciptaan langit, bumi, dan segala sesuatu di antaranya, serta rahmat-Nya yang meluas kepada semua makhluk. Dari segi kontekstual, ayat-ayat ini menggambarkan kebesaran dan rahmat Allah yang berkuasa atas alam semesta, serta sebagai seruan kepada manusia untuk mengenali dan bersyukur kepada-Nya. Di sisi lain, Qs. Al-Anfal ayat 46 menekankan pentingnya ketaatan kepada Allah dan Rasul-Nya, serta memerintahkan umat Islam untuk bersabar dan bertakwa dalam menghadapi ujian dan konflik. Secara kontekstual, ayat ini terkait dengan konteks perang Badar dan memberikan arahan kepada kaum Muslimin dalam menghadapi tantangan dengan keberanian dan kepatuhan kepada ajaran agama. Dengan memahami baik makna tekstual maupun kontekstual dari ayat-ayat ini, umat Islam dapat mendapatkan petunjuk dan inspirasi dalam menjalani kehidupan mereka sehari-hari sesuai dengan ajaran Al-Qur'an.
Repurposing drugs in endometrial cancer using genomic variants database Darmawi, Darmawi; S, Donel; Suhandri, Wiwin; Winarto, Winarto; Adikusuma, Wirawan; Irham, Lalu Muhammad; Fidiawati, Wiwit Ade; Razali, Renardy Reza; Nathania, Auren; Zahra, Leina Putri
Pharmaciana Vol. 13 No. 3 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v13i3.27201

Abstract

Endometrial cancer (EC) is the fourth most frequent gynecological cancers, and its incidence and mortality rates have increased over the last decade. Cytotoxic therapy with carboplatin and paclitaxel is the recommended first-line treatment for EC patients. However, the options for following therapy are limited. The latest advances in molecular studies have uncovered the nature of genetic alterations in EC, compelling methods for further research into the treatment of EC since they may disclose to tailored pharmacological therapy. The aim of this study to identify novel drug candidates in treating EC using genomics variants and biological pathway. The genomic variants of  EC were downloaded from cBioportal database. We established connection between the biological EC risk genes from cBioportal database and the DrugBank database. Finally, we used Connectivity Map (CMap) analysis to identify possible drugs whose mechanisms coincided with therapeutic targets and rank them based on the scoring system. We identified novel potential candidate drugs for EC, they are Bosutinib and Nilutamide which exhibit robust scores in the CMap analysis compare to paclitaxel. We also discovered BCR-ABL1 and AR as potential biomarker-driven therapy in EC. This study demonstrates the possibility of using genetic network analysis combined with bioinformatics to repurpose drugs for the treatment of EC. Further study will investigate the mechanisms of using BCR-ABL1 and AR targeting in the treatment of EC.
Histopathologic Features of Trachea and Lungs in Chickens with Chronic Respiratory Disease Annisa, Aiza; Darmawi, Darmawi; Etriwati, Etriwati; Balqis, Ummu; Salim, M. Nur; Nazaruddin, Nazaruddin; Aliza, Dwinna; Aisyah, Siti; Awaluddin, Awaluddin; Hasan, Denny Irmawati; Akmal, Muslim; Helmi, T. Zahrial; Asmilia, Nuzul
Jurnal Medika Veterinaria Vol 18, No 1 (2024): J.Med.Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v18i1.37429

Abstract

The purpose of this case study is to determine the changes that exist in chickens infected with Chronic Respiratory disease (CRD). A broiler male chicken aged 40 days was found dead in a chicken basket at Ulee Kareng chicken slaughterhouse in a state of feather loss and feces attached to cloaca, on January 6th, 2023. The chicken was brought to pathology laboratory of Faculty of Veterinary Medicine, Universitas Syiah Kuala for necropsy and organ collection. Organs associated with CRD cases were trachea and lungs and histopathological preparations were carried out, stained with Haematoxylin Eosin, and observed under a microscope. The results of histopathological examination showed hemorrhage and hyperplasia of the tracheal epithelium. Hemorrhage was caused by edema which causes increased vascular permeability and epithelial cell hyperplasia occured due to the body's response to infection or inflammation. In the lungs there was bleeding due to damage to the blood vessel wall which caused increased vascular permeability, so that fluid and blood plasma come out of the blood vessels. Fibrinogen then underwent polymerization which resulted in fibrinous thrombi. Congestion happened as the result of fluid accumulation in a location that occured in a passive process so the fluid failed to escape. Because of the accumulation of fluid (congestion), the blood supply to the lung tissue is interrupted, resulting in several points of necrosis in the lungs.
Newcastle Disease Case in Broiler Chicken Angreini, Meliyantika; Balqis, Ummu; Etriwati, Etriwati; Hasan, Denny Irmawati; Aisyah, Siti; Salim, M. Nur; Nazaruddin, Nazaruddin; Darmawi, Darmawi
Jurnal Medika Veterinaria Vol 17, No 2 (2023): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v17i2.35151

Abstract

Newcastle Disease (ND) is a highly contagious disease with a high mortality rate, infecting poultry, and chickens are very susceptible to ND infection. The purpose of this case report is to find out how to diagnose ND disease in chickens. A 30-day-old white male broiler cadaver obtained from Pasar Lambaro, Aceh Besar was found dead in a holding cage with conjunctival hemorrhage and hair loss. Based on the physical examination of the external condition of the cadaver, it can be seen that the eye membranes are experiencing hemorrhage. There was nasal mucosa hemorrhage and mucous exudate in the nasal cavity. The oral mucosa was also found to have mucous exudate, while the cloaca was bleeding and there was residual green feces. The results of anatomic pathology examination found ptechie in the proventriculus and ventricles, swollen lungs with blackish red color and hemorrhage,with the presence of cheese. There was hemorrhage in other organs including trachea, intestines and tonsils, whilst the brain experienced hyperemia. The spleen was swollen and there were foci of necrosis. Based on the anamnesis, external examination, pathological anatomical examination, and histopathology, the diagnosis of the cause of death of broiler chickens was Newcastle Disease (ND).
Diagnostic Accuracy of CA-125 Levels for Ovarian Tumor Patients with Suspected Malignancy Pangaribuan, Machyuddin Tumpak Marojahan; Razali, Renardy Reza; Darmawi, Darmawi
Indonesian Journal of Cancer Vol 19, No 1 (2025): March
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i1.1159

Abstract

Background: Ovarian cancer is a deadly gynecological cancer that appears in ovarian tissue. To detect earlier stages of ovarian cancer and prevent unnecessary surgery, an examination and screening strategy with higher sensitivity and specificity levels are needed. The CA-125 examination is available at Arifin Achmad Hospital and has often been performed on ovarian tumor patients with suspected malignancy. Currently, the accuracy of the CA-125 examination still raises debate in diagnosing malignant ovarian tumors. This study aims to determine the diagnostic accuracy of CA-125 levels in diagnosing ovarian cancer in ovarian tumor patients with suspected malignancy at Arifin Achmad Hospital. Method: This research is an analytical diagnostic test study with a cross-sectional approach, using secondary data recorded from medical records from 2019 to 2022 on ovarian tumor patients with suspected malignancy at Arifin Achmad Regional Hospital.Results: The diagnostic accuracy of CA-125 levels in ovarian cancer is 94.5%, the optimal cut-off value is 36.5 IU/ml, the sensitivity is 86.1%, the specificity is 90.1%, the positive predictive value is 89.4%, the negative predictive value 86.9%. The results of the study showed that there was a significant age difference between benign ovarian tumors and ovarian cancer. The most common histopathological feature of benign ovarian tumors is serous cystadenoma. The most common histopathological feature of malignant ovarian tumors is serous adenocarcinoma. There is a significant relationship between CA-125 levels and ovarian tumors.Conclusion: The identification of CA-125 levels in diagnosing ovarian cancer in ovarian tumor patients with suspected malignancy was a promising test with high diagnostic accuracy level
ANTIBACTERIAL ACTIVITY AND HEMATOLOGICAL PROFILE OF RAT (Rattus norvegicus) DUE TO ADMINISTRATION OF ETHANOL EXTRACT OF SOURSOP FLOWERS (Annona muricata L.) AND Salmonella enteritidis INFECTION Zuraidawati, Zuraidawati; Sugito, Sugito; Darmawi, Darmawi; Taufiq, Taufiq
Jurnal Kedokteran Hewan Vol 14, No 2 (2020): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v14i2.11646

Abstract

This study aimed to determine the antibacterial activity of soursop flower extract (Annona muricata L.) and hematological profile of rats (Rattus norvegicus) due to administration of soursop flower ethanol extract and Salmonella enteritidis infection. The concentrations of soursop flower ethanol extract used for the antibacterial activity test were 25%, 50%, 75%, 100%, with the antibiotic ampicillin 10 g/disk was used s a positive control (PC) and dimethyl sulfoxide (DMSO) 10% as a negative control (NC). For examination of hematological features, 15 male rat aged two months were used. All rats were divided into 5 treatment groups, each consisting of three rats. The NC group was not given soursop flower ethanol extract and S. enteritidis infection. The PC group was not given soursop flower extract but was given S. enteritidis infection. Groups P1, P2, and P3 were given ethanol extracts of soursop flower at a dose of 0.18, 0.36, and 0.72 g/rat/day peroral for a week using gastric sonde. On the following day (after administration of soursop flower extract) the first blood drawing was performed. All rats, except NC group, were then infected with S. enteritidis intraperitonially at dose of 3x108 CFU/mL dose (0.5 mL McFarland). One week after being infected with S. enteritidis, a second blood drawing was performed. The results of the antibacterial activity test showed that there was no antibacterial activity was observed since no inhibition at various concentrations was formed. The administration of soursop flower extract at various dosage levels was able to maintain the number of leukocytes but reduced the number of erythrocytes, hemoglobin concentration, hematocrit value and the number of platelets in rats; whereas S. enteritidis infection decreased all the hematologic features of lab rats.
KOSAKONIA SP. PROTEOLYTIC BACTERIA ISOLATED FROM RUMEN AND RETICULUM OF ACEH CATTLE Safika, Safika; Sari, Wenny Novita; Ademi, Gressha Vionalle; Arsih, Ulfi Widi; Darmawi, Darmawi
Jurnal Kedokteran Hewan Vol 14, No 2 (2020): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v14i2.16426

Abstract

The aim of this study was to identify proteolytic bacteria from the ruminal and reticulum fluids of aceh cattle based on the 16S rRNA gene. Samples used were ruminal and reticulum fluids of aceh cattle slaughtered in Abattoir of Aceh Besar. Samples were diluted and cultured into Skim Milk Agar medium at 39 C for 48 hours. The morphology of bacterial colonies growth in the medium was observed. Colonies resulted in the largest clear zone were isolated and used for Deoxyribonucleic Acid (DNA) isolation, 16S rRNA gene amplification and sequencing. Theresults showed that morphology of dominant colonies was yellowish white color, round shape, position on the agar surface. The results ofphylogenetic analysis of RS1 and ReS2 isolates isolated from rumen and reticulum fluids of aceh cattle respectively had a close familialrelationship and belonged to the bacterial group of Kosakonia. Sequence homology showed isolate RS1 and ReS2 are probably either newEnterobacteriaceae species or unconfirmed species. Halo zone produced by ruminal bacteria had a wider diameter (25 mm vs 20 mm) than thatcaused by reticulum bacteria). Based on the results, RS1 (bacterium in the rumen) and ReS2 (bacterium in the reticulum) belong to similar type, namely Kosakonia sp. with a proteolytic activity. Presumably, these bacteria originate from the rumen that enters the reticulum with degraded feed.
Co-Authors A, Yufrizal Ademi, Gressha Vionalle Aini, Sabrina Ambiyar, Ambiyar Amiruddin Amiruddin Anas, Marnisyah Aneka Firdaus Angraini, Nani Angreini, Meliyantika Annisa, Aiza Apriyan, Dian Arenja, Regina Trisya Arman Sayuti Arsih, Ulfi Widi Arwizet Arwizet, Arwizet Awaluddin Awaluddin Beočanin, Anđelija Budi Syahri budianto panjaitan Chatarina Umbul Wahyuni Dion, Selin Dwinna Aliza Dwisnu, Erlian Erianza, Dava Erwin Erwin Etriwati E Fadhil Fuad Rachman Ferdian, Riyan Giovani, Edo Habibie, Maulana Hasan, Denny Irmawati Hasan, Maryatun Helmi, T. Zahrial Heni Pujiastuti Husni Hidayat Irwin Bizzy Jamil, Kurnian Fitri Kamaludin, Saman Khairussyifa, Najmi Kurnia F. Jamil Kusuma, Herwin Wijaya Lalu Muhammad Irham Liansyah, Tita M. M Amin Indra Putra M. Nur Salim M. Syukri Ismail Maimun Syukri, Maimun Maryanti, Yossi Moliwati, Moliwati MS, Firdaus Mukamal, M. Farda Insan Muslim Akmal N. Nazaruddin Nathania, Auren Ningrum, Sania Devita Nora Usrina Nurhaspika, Nurhaspika Nuzul Asmilia Ofiani, Oktawini Pangaribuan, Machyuddin Tumpak Marojahan Prawana, Yogi Ramadhani, Fitria Sari Razali Daud Razali, Renardy Reza S, Donel Safika S, Safika Saud, Eddy Setiawan, Sepdirama Sibuan, Sibuan Siti Aisyah Solly Aryza Sugeng Prasetyo Sugito - Suhandri, Wiwin Sukma, Zahwa Tamara Sumanto Sumanto Suparno Suparno Syafruddin Syafruddin Tabrani, Tabrani Taufiq Taufiq Ummu Balqis Usman, Said Wenny Novita Sari Winarto Winarto Wirawan Adikusuma Wiwit Ade Fidiawati Yenni Yusriani Yuliani Yuliani Zahra, Leina Putri Zamzami, Rumi Sahara Zikra, Izza Fattalia Zulkifli, Baidillah Zuraidawati Zuraidawati, Zuraidawati