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All Journal International Journal of Evaluation and Research in Education (IJERE) JURNAL GIZI INDONESIA Jurnal Kedokteran Brawijaya Jurnal Kesehatan Andalas Jurnal NERS Global Medical and Health Communication Jurnal Media Gizi Indonesia (MGI) The Indonesian Journal of Public Health Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Penelitian Kesehatan Suara Forikes Health Notions Jurnal Gizi Klinik Indonesia Argipa (Arsip gizi dan Pangan) Amerta Nutrition International Journal of Nursing and Health Services (IJNHS) Jurnal Ilmu Kefarmasian Indonesia Adi Husada Nursing Journal Media Gizi Kesmas Indian Journal of Forensic Medicine & Toxicology Makara Journal of Health Research Strada Jurnal Ilmiah Kesehatan (SJIK) Jurnal Widya Medika Folia Medica Indonesiana
Merryana Adriani
Departemen Gizi Kesehatan Fakultas Kesehatan Masyarakat Universitas Airlangga, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : Health Notions

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Cocoa Liquor Increases SOD Activity in Wistar Rats Experiencing Oxidative Stress Dwi Putra, Kartika Wahyu; Wirjatmadi, Bambang; Purwanto, Bambang; Adriani, Merryana
Health Notions Vol 2 No 1 (2018): January, 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Young Khalaal Dates (Phoenix dactylifera) Effect on Blood Glucose in Alloxan-induced Wistar Male Rats Sholikhah, Desty Muzarofatus; Wirjatmadi, Bambang; Adriani, Merryana
Health Notions Vol 2 No 1 (2018): January, 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Young Khalaal Dates (Phoenix dactylifera) Effect on Blood Glucose in Alloxan-induced Wistar Male Rats
Bee Pollen Effect on Blood Glucose Levels in Alloxan-induced Male Wistar Rats Rahayu, Aprilia Nurcahyaning; Wirjatmadi, Bambang; Adriani, Merryana; M., Soenarnatalina; Winarni, Dwi; Hartiningsih, Sri
Health Notions Vol 2 No 1 (2018): January, 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Influence of Cinnamon Extract (Cinnamomum burmanii) Provision on the Reduction of Blood Glucose Level of Hyperglycemic Male Wistar Rats Aulia, Kharina; Wirjatmadi, Bambang; Adriani, Merryana
Health Notions Vol 2 No 3 (2018): March 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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The number of patients with hyperglycemia in the world and in Indonesia is estimated to increase rapidly in the next 25 years. The content of cinnamaldehyde, flavonoids, polyphenols, and chromium in cinnamon thought to have an influence of hypoglycemia. This study aimed to determine the influence of cinnamon extract to a decrease of blood glucose levels in hyperglycemic rats induced by a single dose of alloxan as much as 125 mg/kg. This study was laboratory experiment by using RAL (Complete Randomize Design) with Pre-Post Test Control Group Design Research. Experimental animals used were male Wistar rats divided into 5 groups. KN was negative control group. KP was hyperglycemic positive control group. P1 was the first treatment group (a dose of 200 mg/kg). P2 was the second treatment group (a dose of 250 mg/kg). P3 was the third treatment group (a dose of 300 mg/kg). Cinnamon therapy was given orally for 14 days. The results of this research was tested statistically by using One Way ANOVA and showed that there were significant differences between the blood glucose levels in the treatment group with the positive and negative control groups. The conclusion was that the provision of cinnamon extract for 14 days could provide an influence of lowering blood glucose levels.  Keywords: Blood glucose, Cinnamon, Hyperglicemia
Effects of Purple Sweet Potatoes on Oxidative Stress Biomarkers in Rats Subjected to Exhaustive Exercise Sholikhah, Anindya Maratus`; Wirjatmadi, Bambang; Adriani, Merryana
Health Notions Vol 2 No 2 (2018): February 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Oxidative stress is a condition caused by the imbalance between the production of free radicals or ROS and the antioxidants; the level of free radicals is higher than the antioxidants. Exhaustive exercise is one of the causes of this oxidative stress. However, it can be reduced by antioxidants found in purple sweet potatoes (PSP) (Ipomoea batatas L). This study aims to evaluate the effect of two weeks supplementation of PSP extract on rats inducedoxidative stress. Twenty rats were distibuted into four groups consisted five rats each. Rats in the treatments groups were administered PSP extract for two weeks then were forced to swim until exhausted. Bloods from all samples were drawn to see the changes in the levels of malondialdehyde ans superoxide dismutase after two weeks of treatment. The data was then analyzed using descriptive and inferential statistic. The results showed that mean level of MDA and SOD differ significantly (p<0.05) between groups after the administration of PSP extract as well as after exhaustive exercise. The extracts and exhaustive exercise concurrently showed a significant effect on oxidative stress biomarkers (p<0.05). It concluded that PSP extract can protect cells against free radical produced by exhaustive exercise. 
The Role of Addition of Vitamin C in Iron Supplementation on Ferritin Serum Levels in Anemia Adolescent Females Astuti, Nanik Dwi; Wirjatmadi, Bambang; Adriani, Merryana
Health Notions Vol 2 No 3 (2018): March 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Prevention of iron deficiency anemia in Indonesia using ferrous sulfas blood-added tablets started since 1997. But iron deficiency anemia is still high, also in young women. Young women are vulnerable because of rapid growth and unhealthy their consumption patterns, which rarely consume fruits and vegetables that are a source of vitamin C. The purpose of this study was to analyze the addition of vitamin C in iron supplementation + folic acid to serum ferritin levels in adolescents females anemia. This research was an experimental quasi research. Design of research was Randomized Pre Post Test Control Group Design, with Double Blind treatment. This study had one treatment group and one control group, each group of 11 samples. The samples were chosen randomly with inclusion and exclusion. The collected data was processed using SPSS program with the analysis of paired t-test and independent t-test to test the difference of serum ferritin level. The results was showed the characteristics of respondents: age (p = 0.430), education of mother (p = 0.942) and nutritional knowledge of respondents (p = 0.928) in the same condition or both groups were had homogeneous characteristics. The pattern and level of food consumption were showed no different between control and traetment groups (p> 0.05). Serum ferritin levels showed difference between the two groups after treatment (p = 0.004). The study was showed vitamin C had role in increasing iron absorption and fill in storage of ferritin formation. Keywords: Anemia, Vitamin C, Iron supplement, Ferritin
The Effect of Dayak Onion Bulb-Stem (Eleutherine Palmifolia (L.,) Merr.) Extract on Blood Glucose Levels of Mouse Suffered Diabetes Mellitus Arwati, Niluh; Wijatmadi, Bambang; Adriani, Merryana; Meilanani, Soenarnatalina; Winarni, Dwi; Hartiningsih, Sri
Health Notions Vol 2 No 3 (2018): March 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Dayak onions (Eleutherine Palmifolia (L.) Merr.) bulb stem contains phtyochemical contents, which act as antidiabetic compounds, such as eleutherol, eleuthocide A, and eleutherinoside B, as well as antioxidant compounds, which include triterpenoid, poliphenol, and flavonoid. Dayak onions was able to be used as the antidiabetic, since it had the ability to lower the blood glucose level and prevent from the free radicals, thus supressing the oxidative stress condition. This research had purpose to analyze the effect of Dayak onions bulb-stem as antioxidant and anti diabetic drugs. The research used experimental method with the population in this research was 25 male white mice strain wistar. The concentration of Dayak onions bulb-stem extracts were 300mg.kgBW-1, 400mg.kgBW-1, and 500mg.kgBW-1. Data analysis used Tukey HSD Test with 95% of  significance degree and was continued using manova test (average group ratio test). The result showed that. the extract of Dayak onions bulb-stem had the antidiabetical and antioxidant activity, which could lower the blood glucose levels and malondialdehid on the male white mice strain Wistar with the optimum effective doze of 500 mg.kgBW-1.   Keywords: Dayak onions bulb-stem, Blood glucose level, Malondialdehid (MDA)
Green Tea (EGCG) Decreases Malondialdehide In Oxidative Stress Exposure To Psychological Stress Priaminda, M Dodi F; Wirjatmadi, Bambang; Purwanto, Bambang; Adriani, Merryana
Health Notions Vol 2 No 7 (2018): July 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Expression of VCAM in Male Wistar Rats (Rattus norvegicus) with Hypercholesterolemia Supplemented with Pumpkin Seeds (Cucurbita moschata Duch) Extract Proboningsih, Jujuk; Wirjatmadi, Bambang; Kuntoro, Kuntoro; Adriani, Merryana
Health Notions Vol 2 No 6 (2018): June 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Treatment of cardiovascular diseases tends to be expensive and requires long-term therapy. Investigation about the effect of pumpkin seeds on prevention of endothelial dysfunction of blood vessel has never been reported yet, accordingly, bodies of research are required to know its effectiveness. This study aimed to analyze the expression of Vascular Cell Adhesion Molecule (VCAM) in male Wistar rats (Rattus norvegicus) with hypercholesterolemia supplemented with pumpkin seeds extract (Cucurbita moschata Duch). This was an experimental laboratory study with randomized post-test control group design. The independent variable was pumpkin seeds extract, and the dependent one was expression of VCAM. Data analysis employed chi-square test to test the difference between control and treatment groups. Study results showed that there was significant difference (p=0.000) between VCAM expression in group-K2 (positive control) as compared to group-K1 (negative control) and group-K5 (treatment group-dose 3) α=0.001, whereas no significant difference was found between that of as compared to group-K3 (treatment group-dose 1) α=0.125 and group-K4 (treatment group-dose 2) α=0.05. The study showed reduction of VCAM expression in treatment groups consisted of male Wistar rats with hypercholesterolemia supplemented with pumpkin seeds (Cucurbita moschata Duch) extract. Keywords: Pumpkin seeds, VCAM expression, hypercholesterolemia
The Role of Nutritional Status, Dietary Pattern, and Free Radical in the Insulin Resistance Development Sari, Meirna Dewita; Wirjatmadi, R. Bambang; Adriani, Merryana
Health Notions Vol 1 No 4 (2017): October-December 2017
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Insulin resistance is an early sign of diabetes type 2 that occurs in situations where target organ sensitivity decreases against insulin. Excess free radicals can be mutually insulin resistance. The purpose of this study was to determine how the effects of insulin can be a determining factor. This study used case control design conducted on 22 outpatients at Clinic University of Muhammadiyah Surabaya during June until July 2017. Data were collected using questionnaires, nutritional status, fasting blood glucose, fasting insulin, and MDA levels. Insulin resistance status using normal HOMA IR method of <2,77. Logistic Regression was used to determine the effect of free radical on the occurrence of insulin resistance. The results showed free radical against insulin resistance at a=0,05 with p=0,018. That result means boosting MDA levels also increases the risk of insulin resistance. In addition, the consumption of dietary sources of fat and excessive use of food additives, low fruit intake, BMI values are also factors affecting insulin resistance with p=0,027; p=0,036; and p=0,027. Given the elevated levels of MDA-free radicals can increase the risk of insulin resistance. Applying a healthy lifestyle by consuming fiber-rich foods can prevent the formation of excessive free radicals. Keywords: Insulin Resistance, Free Radical, HOMA IR
Co-Authors Abdillah, Bagus Ahmad Nur Abu Bakar Achmad Ali Basri Ade Saputra Nasution Aditia Rida Purnamasari Agus Sulistyono Ajeng Putri Rahmandita Amanda Nurqisthy Anindya Mar’atus Sholikhah Anisatun Azizah Annis Catur Adi Annisa Rachma Firdausi Darmawan Aprilia Nurcahyaning Rahayu Arinda Lironika Suryana Arwati, Niluh Arwati, Niluh Arya Ulilalbab Astuti, Nanik Dwi Aulia, Kharina B Wirjatmadi Bambang Purwanto Bambang Purwanto Bambang Purwanto Bambang Wiratmadi Bambang Wirjadmadi Bambang Wirjatmadi BAMBANG WIRJATMADI Bambang Wirjatmadi Bambang Wirjatmadi Bambang Wirjatmadi Bambang Wirjatmadi Bambang Wirjatmadi Bambang Wirjatmadi Brigita Rainy Oktiva Candra Panji Asmoro, Candra Panji Cici Damayanti D.A. Liona Dewi Denna Rahinda Yulia Fanni Desy Prasetya Desy Prasetya, Desy Dewi Retno Suminar Dini Ririn Andrias Dini Setiarsih Dwi Putra, Kartika Wahyu Dwi Winarni Elida Ulfiana Fajar Afrindo Fara Disa Durry Farapti Farapti Fatifa Asmarani Fatifa Asmarani, Fatifa Fika Mayrlina Anggrayni Haryana, Nila Reswari Hermadani, Candraningtyas Ika Nur Pratiwi Ikhram Hardi S Indarwati , Retno Intan Galih Cornia Jayanthi Petronela Janggu Jayanthi Petronela Janggu Jujuk Proboningsih, Jujuk Junaida Astina Kartika Wahyu Dwi Putra Kharina Aulia Kuntoro Kuntoro Kuntoro Kuntoro Kusnanto Kusnanto Kusnanto Kusnanto Laila Nurayati Lailatul Muniroh Lailatun Ni'mah Laily Hidayati Lestari, Annisa Arifiana Lury Novita Yustianingrum M. Dodi F Priaminda M., Soenarnatalina Mahmud Aditya Rifqi Maria Widijanti Sugeng Meirna Dewita Sari Muhammad Dimas Bimantara Mustika Putri Kustiyoasih Nanik Dwi Astuti Nathania Helsa F. Losong Ni Putu Wahyuningsih Nina Agustina Novera Herdiani, Novera Nur Nashriana Jufri Nursalam Nursalam Nursalam, Nursalam Oktovina Rizky Oktovina Rizky, Oktovina Pei-Lun Hsieh Priaminda, M Dodi F Pudji Astutik Pudji Astutik, Pudji Puspita Ayu Ramadhani Rachmah, Qonita Rachmat Hargono Raharja, Kristian Triatmaja Rahayu, Aprilia Nurcahyaning Rahmi Syarifatun Abidah Rahmi Syarifatun Abidah, Rahmi Syarifatun Ratna Sari Rumakey Reineldis Trisnawati Rifka Laily Mafaza Rina Wasesa Aprilia Lazulfa Rista Fauziningtyas, Rista Rivan Virlando Suryadinata Rivan Virlando Suryadinata Rivan Virlando Suryadinata Rizka Amalia Habiba Rosita Andriani Santi Kusumastuti Setho Hadisuyatmana Setiarsih, Dini Sheila Monica Kelly Amalia Sheryll Deby Regyna Sholikhah, Anindya Maratus` Sholikhah, Desty Muzarofatus Shrimarti Rukmini Devy Silviana Putri Siti Nur Qomariah Siti Rahayu Nadhiroh Soenarnatalina M. Soenarnatalina Meilanani Soenarnatalina Meilanani, Soenarnatalina Sri Hartiningsih Sri Hartiningsih Sri Hartiningsih Stefani Cornelia Sardjono Susanti, Yuyun Erlina Susanti, Yuyun Erlina Susila Rusdiana Dewi Tia Eka Novianti Tri Martiana Tri Ratna Ariestini Triharini, Mira Triska Susila Nindya Wijatmadi, Bambang Windhu Purnomo Wiratmadi, Bambang Yayuk Estuningsih Yeni Susanti