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Amlodipine-Candesartan Combination: A Cost-Effective Strategy for Successful Therapy of Hypertension Fitria, Najmiatul; Zazna Syaputri, Yolanda; Mardatillah, Mardatillah; Akram, Muhammad; Nasif, Hansen
JSFK (Jurnal Sains Farmasi & Klinis) Vol 11 No 1 (2024): J Sains Farm Klin 11(1), April 2024
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.11.1.32-38.2024

Abstract

Introduction: The combination of amlodipine and candesartan can have a better effect, although the cost-effectiveness analysis was not yet determined. This research aimed to establish the Incremental Cost-Effectiveness Ratio (ICER) value among outpatients with hypertension who used amlodipine-candesartan. Method: This research is a descriptive study that retrospectively gathered data from medical records. It focused on information for hypertensive patients at Universitas Andalas Hospital in 2021. This study compared the standard treatment involving amlodipine-candesartan and sole amlodipine, next to calculate the ICER using cost-effectiveness analysis. Results: Out of the total population of 284, as many as 73 patients were involved in this study. Among these, 21 patients (28.77%) were treated with amlodipine alone, while 52 (71.23%) received an amlodipine-candesartan combination. The Incremental Cost-Effectiveness Ratio (ICER) for reducing systolic blood pressure was IDR 74,738.10 per one mmHg decrease in the northeast quadrant of the cost-effectiveness chart. The ICER for lowering diastolic blood pressure was IDR 205,918.24 per one mmHg decrease in the northeast quadrant on the cost-effectiveness chart. Conclusion: The cost of the amlodipine-candesartan combination yields superior effects; however, warranting a probabilistic sensitivity analysis to determine its ICER robustness is essential for its effective implementation
PENGARUH PROMOSI, EKUITAS MEREK DAN KUALITAS LAYANAN TERHADAP KEPUASAN PELANGGAN PADA TOKO LAGOS BRANDED KRUENG MANE, ACEH UTARA Muhammad Akram; Chalirafi Chalirafi; Ikramuddin Ikramuddin; Muchsin Muchsin
Jurnal Intelek Insan Cendikia Vol. 2 No. 5 (2025): MEI 2025
Publisher : PT. Intelek Cendikiawan Nusantara

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Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh promosi, ekuitas merek, dan kualitas layanan terhadap kepuasan pelanggan pada Toko Lagos Branded Krueng Mane, Aceh Utara. Kepuasan pelanggan menjadi indikator utama dalam menentukan keberhasilan suatu bisnis di tengah persaingan yang semakin kompetitif, terutama dalam industri fashion retail. Metode penelitian yang digunakan adalah kuantitatif dengan pendekatan asosiatif. Sampel penelitian sebanyak 100 responden diperoleh melalui teknik purposive sampling. Teknik analisis data yang digunakan meliputi uji validitas, reliabilitas, regresi linear berganda, dan uji hipotesis (uji t dan uji F). Hasil penelitian menunjukkan bahwa promosi, ekuitas merek, dan kualitas layanan berpengaruh secara signifikan terhadap kepuasan pelanggan. Di antara ketiga variabel tersebut, kualitas layanan memiliki pengaruh paling dominan terhadap kepuasan pelanggan. Dengan demikian, peningkatan pada aspek layanan serta strategi promosi yang tepat dan penguatan citra merek sangat disarankan untuk mempertahankan dan meningkatkan kepuasan pelanggan di masa depan.
Pertimbangan Hakim Terhadap Pernyataan Kepailitan Badan Usaha Milik Negara (BUMN) Muhammad Akram; Sabir Alwy; Andi Tenri Famauri
Jurnal Kewarganegaraan Vol 6 No 4 (2022): Desember 2022
Publisher : UNIVERSITAS PGRI YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31316/jk.v6i4.4348

Abstract

Abstrak Penelitian ini bertujuan untuk mengetahui dan menganalisis permohonan pernyataan pailit terhadap BUMN dan Pertimbangan Hakim Terhadap BUMN yang dinyatakan pailit. Dengan menggunakan metode penelitian hukum normatif. Bahan hukum yang di peroleh kemudian disusun secara sistematis selanjutnya dianalisis secara kualitatif untuk mencapai kejelasan masalah yang akan diteliti. Hasil penelitian yang diperoleh menunjukkan bahwa Pasal 2 ayat (5) UUK-PKPU mengharuskan permohonan pernyataan pailit hanya dapat diajukan oleh Menteri Keuangan. Terlebih lagi dalam Putusan MK Nomor 48/PUU-XI/2013 dan Putusan MK Nomor 62/PUU-XI/2013 menyatakan bahwa status kekayaan BUMN merupakan Kekayaan Negara. Berdasarkan kedua Putusan MK tersebut juga dapat menjawab terkait dengan banyaknya interpretasi dari Pasal 2 ayat (5) tersebut. Kemudian Pertimbangan Hakim dalam memutuskan kepailitan terkait dengan PT. Kertas Leces (Persero) sudah berdasarkan ketentuan Pasal 291 UUK-PKPU dan dalam pembuktiannya di persidangan, terbukti lalai dalam memenuhi isi dari perdamaian, mengakibatkan PT. Kertas Leces (Persero) dinyatakan pailit. Terhadap pertimbangan hakim dalam upaya hukum peninjuan kembali yang dilakukan tersebut sudah tepat sesuai ketentuan Pasal 293 UUK-PKPU yang bahwa terkait pembatalan perdamaian tidak terbuka upaya hukum. Kata kunci: Hukum Kepailitan, Badan Usaha Milik Negara (BUMN), Kepailitan BUMN, Kekayaan BUMN Abstract This study aims to find out and analyze the request for bankruptcy statements of SOEs and judges' considerations of SOEs declared bankrupt. By using normative legal research methods. The legal material obtained is then arranged systematically and then analyzed qualitatively to achieve the clarity of the problem to be examined. The results of the study showed that Article 2 paragraph (5) of the UUK-PKPU required the request for bankruptcy statements to only be submitted by the Minister of Finance. Moreover, in the Constitutional Court's decision Number 48/PUU-XI/2013 and MK Decision Number 62/PUU-XI/2013 states that the status of BUMN wealth is a state wealth. Based on the two Constitutional Court decisions, they can also answer related to the number of interpretations of Article 2 paragraph (5). Then the judge's consideration in deciding bankruptcy related to PT. Paper leces (Persero) is based on the provisions of Article 291 of the UUK-PKPU and in its proof at the trial, proven to be negligent in meeting the contents of peace, resulting in PT. Paper leces (Persero) is declared bankrupt. Regarding the judge's consideration in the legal remedies carried out the exactly carried out in accordance with the provisions of Article 293 of the UUK-PKPU which related to the cancellation of peace is not open to legal efforts. Keywords: Bankruptcy Law, State -Owned Enterprises (BUMN), BUMN Bankruptcy, BUMN Wealth
Analisis Variasi Jenis Perekat Tetes Tebu dan Tepung Tapioka Pada Pemanfaatan Limbah Ampas Tebu Menjadi Briket Mufti, Aulia Annas; Akram, Muhammad; Lisafitri, Yuni; Kurnianingtyas, Erlina
Al-Ard: Jurnal Teknik Lingkungan Vol. 9 No. 2 (2024): March
Publisher : Department of Environmental engineering, Faculty of Science and Technology, Islamic State University Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/alard.v9i2.1857

Abstract

Energy is a factor that has a very important role in various economic activities and people's lives. The availability of energy and fuel oil is currently lacking, indicating the need to switch to alternative fuels, one of which is charcoal briquettes. Sugarcane bagasse is one of the many biomasses that can be used. as a raw material for making briquettes. The process of making charcoal briquettes requires additional material in the form of an adhesive whose purpose is to glue the charcoal powder so that it becomes a solid form. As a binder for briquettes, molasses has the potential to increase the calorific value because it is rich in carbon content derived from sucrose which is abundant in molasses. Therefore, a study was conducted to analyze the fuel characteristics of bagasse briquettes with adhesive variations in the form of tapioca flour and molasses. The parameters to be tested are moisture content, ash content, volatile matter content during the heating process, bound carbon and heating value. Research on the production of charcoal briquettes was carried out using bagasse waste with variations in the addition of tapioca adhesive and molasses. It can be concluded that the best quality briquettes are A1 briquettes, namely bagasse briquettes with 0.5 gram of adhesive drops, which are close to the standard criteria of briquettes, namely the highest calorific value, lowest moisture content, lowest ash content and lowest volatile matter content.