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All Journal METAMORFOSA Journal of Biological Sciences Jurnal Biologi Udayana Jurnal Kedokteran Brawijaya AL KAUNIYAH El-Hayah : Jurnal Biologi Biology, Medicine, & Natural Product Chemistry Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Universa Medicina Jurnal Biologi Tropis Pharmasipha Journal of Dedicators Community Biota Jurnal Kesehatan Islam : Islamic Health Journal INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Jurnal Pemberdayaan Masyarakat Universitas Al Azhar Indonesia Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Jurnal Riset Biologi dan Aplikasinya JSMARTech : Journal of Smart Bioprospecting and Technology BioEksakta : Jurnal Ilmiah Biologi Unsoed J-PEN Borneo : Jurnal Ilmu Pertanian Jurnal Sains Alami (Known Nature) Berkala Penelitian Hayati JURNAL AGROINDUSTRI HALAL Agrikan: Jurnal Agribisnis Perikanan Jurnal Kedokteran Hewan Jurnal Sains Alami (Known Nature) ICONESTH KOPEMAS
Nour Athiroh Abdoes Sjakoer
Universitas Islam Malang
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : METAMORFOSA Journal of Biological Sciences

 1 
Kadar Superoksida Dismutase (SOD ) Pada Paru-Paru Tikus Hipertensi Doca-Garam Yang Dipapar Ekstrak Metanolik Benalu Teh Dan Benalu Mangga Siti Qurrotul Aini; Nour Athiroh Abdoes Sjakoer; Nurul Jadid Mubarakati
Metamorfosa: Journal of Biological Sciences Vol 8 No 2 (2021)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2021.v08.i02.p13

Abstract

Hypertension is a condition caused by the pressure of blood against the artery walls when the blood is Hypertension is a condition caused by the pressure of blood against the artery walls when the blood is pumped from the heart to the tissues. In hypertension, it can stimulate the formation of reactive oxygen species (ROS) compounds. The use of exogenous antioxidants in preventing oxidative stress can alternatively use herbal plants. For example, herbal plants such as tea parasites and mango parasites can increase the activity of superoxide dismutase (SOD) and reduce the concentration of malondialdehyde (MDA). This study aims to further examine the role of methanolic extracts from the combination of tea parasite and mango parasite (EMBTBM) on superoxide dismutase (SOD) in hypertensive rats exposed to DOCA-salt using experimental methods. Using 25 male Wistar rats, consisted of 5 treatments, namely control (-), control (+), the treatment group for the combination of tea parasites and mango parasites with doses of 50, 100, and 200 mg / KgBB respectively with five repetitions. The results of this study indicate that the level of increased SOD with the combination of EMBTBM in the control group (+) was very significantly different from the control group (-), treatment 1, 2, and 3. This very significant difference was due to the p-value = <0.001 (< 0.05). The benefit of this study is that it can be used as a reference for the role of the combination of tea parasites and mango parasites on superoxide dismutase (SOD) in hypertensive rats exposed to DOCA-salt. Keywords: Hypertension, EMBTBM, SOD.
Profil Histopatologi Otot Jantung pada Tikus Hipertensi (Doca-Garam) yang Dipapar Kombinasi Ekstrak Metanolik Benalu Teh Dan Benalu Mangga (EMBTBM) Annisatul Anis Hakimah; Nour Athiroh Abdoes Sjakoer; Nurul Jadid Mubarakati
Metamorfosa: Journal of Biological Sciences Vol 8 No 2 (2021)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2021.v08.i02.p20

Abstract

Some herbs from the parasite group and the Loranthaceae family also act as antihypertensives. This study aims to look at the histopathological profile of the heart in hypertensive rats (DOCA-Salt) exposed to the combination of Methanolic Extract of Benalu Tea and Mango Benalu (EMBTBM) for 14 days using true experimental design method with completely randomized design on 50 rats, divided into 5 controls -), control (+), treatment 1 dose 50 mg / KgBB, treatment 2 doses 100 mg / KgBB and treatment 3 doses 200 mg / KgBB. Each treatment had 5 replications. In analyzing the data used the ANOVA test, one of the methods is JAMOVI with version 1.1.9.0. As for the calculation of cell diameter using the IMAGE J application. The results showed that the histopathological profile of the heart in hypertensive rats (DOCA-Salt) exposed to EMBTBM for 14 days on heart cell necrosis showed very real evidence between the control (+) and control (- ), treatment 1, 2, and 3. This is evidenced by the results of the analysis p-value <0.05, namely 0.002, so it is denied that EMBTBM has an effect on the average number of necrosis of cardiac cells. There is also a significant difference in the number of heart cell diameter of hypertensive rats between the control (+) and control (-) groups, treatment 1, 2, and 3. This is evidenced by the results of the analysis showing a p-value <0.05, namely 0.021, so that it can it is denied that EMBTBM can shrink the diameter of cells in the heart organ. Keywords: Hypertension, Heart, Left Ventricle, Anatomical Histopathology, EMBTBM.
Co-Authors Abdur Rohman Wahid Ahmad Baidarus Ahmad Taufiq Aisyah Aisyah Aldina, Devana Rahma Andini, Saskia Ade Hutami Fery Anita Puspa Widiyana Anna Fathiah Annisatul Hakimah Ar Rahmah, Mumtazunnisa As Sufiyah Argus Argus Argus Mahyan Ari Hayati Ari Hayati Arina Roikhana Ariski Vevi Liswandari Ayu Pertiwi, Chintya Baidarus, Ahmad Dea Fatimatu Zahroh Devi Qurroti A'yun Dewi Qurrot &#039;Aini Dewi Qurrot 'Aini Doti Wahyuningsih Durrotul Hasanah Dwi Mareta Nur hidayati Dyan Aprillia Susanti Eka Kumalasari Eko Noerhayati Erna Sulistyowati Erna Susanti fahmiy, Rakhmawati Faisal Faisal Fajrin, Siti Awaliah Fatimah Abdul Sammad fatimah Fatimah Fatimah Fatimah Fatur rohman Rohman Forrela Zahwa Salamah Gatra Ervi Jayanti Gemilang, Satria Hari Santoso Hari Santoso Hari Santoso Hari Santoso Hari Santoso hari santoso Hasan Zayadi Hatif Khusnin Nida' Herlinda Rahayu Husain Latuconsina Husain Latucosina Husain, Muhammad Hafizh Istirochah Pujiwati Jadid Mubarakati, Nurul Jihan Farah Zakia Laili Mihmidati Lestari, Tengku Anggun Luluk Rofiatul Mafluhah M. Abdul Qodir Jailani M. Mas’ud Said Ma'ruf, Muhammad Mahanem Mat Noor, Mahanem Mat Mahyantika, Seftya Putri Maidhatul Rosidha Widyanti Majida Ramadhan Malia Anjani Mardhiyah, Mardhiyah Masyhuri Masyhuri Mihmidati, Laili Mohammad Mabrur Mubarokati, Nurul Jadid Muhammad Fahmi Hidayatullah Nafisa Nafisa Nafisa, Nafisa Nia Novita Nurrohmah Nirwana, Linggar Nur hidayati, Dwi Mareta Nur Mufida Nur Permatasari Nur Shofiyah Munawaroh Nur Shofiyah Munawaroh, Nur Shofiyah Nurrohmah, Nia Novita Nurul Jadid Mubarakati Nurul Jadid Mubarakati Nurul Jadid Mubarakati Nurul Jadid Mubarokati Oktaviana, Nimas Ajeng Rahayu Dwi Lestari Rahmawati, Rizka Dwi Rakhmawati fahmiy Ramadhan, Majida Ramadhani, Mieta Widya Ratna Djuniwati Lisminingsih Ratna Juniwati Lisminingsih Rizki Kusuma Hantika Saimul Laili Salamah, Forrela Zahwa Saputri, Syntia Diyah Hayu Ria Savana, Amartya Gesit Shinta mayangsari Sholikha alaiya Sholikha alaiya, Sholikha Silfi hamidatul lailiyah Silvia, Putri Azizatul Siti Asmaniyah Mardiayani Siti Awaliah Fajrin Siti Imama Khoiriyah Siti Qurrotul Aini Suroyya, Mariyam Susanti, Dyan Aprillia Tengku Anggun Lestari Umu Intan Kinasih Uyunul Hikmah Wahidah, Shinta Nuriyah Yudi Purnomo Zahroh, Dea Fatimatu Zakia, Jihan Farah