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Journal : Bioinformatics and Biomedical Research Journal

Phenol Coefficient Test Combination Infusion of Cananga odorata – Averrhoa bilimbi L. Against Staphylococcus aureus and Salmonella typhi in Vitro Budiarti, Lia Yulia; Wydiamala, Erida; Ulfa, Najiya
Bioinformatics and Biomedical Research Journal Vol. 4 No. 1 (2021): Vol 4 No 1 (2021)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bbrj.04.01.03

Abstract

Cananga odorata (kenanga) flowers and Averrhoa bilimbi L. (belimbing wuluh) fruit are plant parts that contain relatively the same antibacterial compounds, namely flavonoids, saponins, and tannins. Both of these plants can be developed as an alternative natural antiseptic preparation, which is made in the form of a combination infusion. The effectiveness of an antiseptic preparation is measured by the coefficient value of the phenol antiseptic substance compared to 5% phenol against several standard test bacteria. This study aims to determine the antibacterial activity of the combination infusion of Cananga odorata flower - Averrhoa bilimbi L. fruit against Staphylococcus aureus ATCC 25923 and Salmonella typhi ATCC 19430 based on the in vitro phenol coefficient test. The phenol coefficient test method was carried out conventionally. The coefficient value close to 1 can be said that the antiseptic preparation has good activity and is equivalent to the phenol coefficient value as a comparison. The results showed that the mean coefficient of the phenol coefficient of the combination infusion of Cananga odorata flower - Averrhoa bilimbi L. fruit was 0.91 against S. aureus and 0.83 against S. typhi. The conclusion of this study, the antibacterial activity of the combination infusion of Cananga odorata flower - Averrhoa bilimbi L. fruit against Staphylococcus aureus obtained a higher phenol coefficient value than Salmonella typhi.
Antimicrobial Activity of Stenochlaena palustris and Sauropus androgynus in Staphylococcus aureus, Escherichia coli and Candidia albicans Budiarti, Lia Yulia; Isnaini, Isnaini; Dayana, Puteri; Sari, Norma; S., Nur Almira R.
Bioinformatics and Biomedical Research Journal Vol. 4 No. 1 (2021): Vol 4 No 1 (2021)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bbrj.04.01.05

Abstract

Stenochlaena palustris and Sauropus androgynus are known to contains antimicrobial substances such as flavonoids, saponins and tannins compounds.The purpose of this study was to analyzes the antimicrobial activity of young and old leaf infusions of S. palustris and S. androgynus leaves against Staphylococcus aureus, Escherichia coli and Candida albicans. Analyze the antibacterial activity of a single preparations with a combination preparation of S.palustris (SP) and S.androgynus (SA) leaves infusion against S.aureus, E.coli and C.albicans. Leaves of S.palustris young part (SP1) taken 0-10 cm from shoots and old parts (SP2) 11-20 cm from shoots, while leaves of S.androgynus young part (SA1) leaves number 1 - 10 from the top and the old part (SA2) leaves number 11-20 from the top. The results showed that a single infusion of SP1 75% and SP2 75%, SA1 90% and SA2 90%, and a combination of SP1 75% and SA1 75%, SP2 75% and SA2 75% have the same activity as ampicillin in S.aureus. Single infusion of SP1 90% and SP2 90%, SA1 90% and SA2 90%, combination of SP1 75% and SA1 80% and the combination of SP2 80% and SA2 60% have the same activity as ciprofloxacin in E. coli. Single infusion of SP1 90% and SP2 90%, and a combination of SP1 80% and SA1 80%, SP2 80% and SA2 80% have the same activity as ketoconazole in C.albicans. The difference in activity due to differences in leaf parts used only occurred in E. coli, whereas in S.aureus and C.albicans (p <0.05).
Co-Authors A.A. Ketut Agung Cahyawan W Abdurahman Wahid Agung Biworo Agung Biworo Aisyah Aisyah Akbar Rihansyah, Akbar Alfi Yasmina Alfi Yasmina Alfia Fitriani, Alfia Alshazil, Renata Seikh Amalia, Maulidia Khairada Amalya, Khalida Zikra Amiratun Naillah Anward, Aliy Arivin Ari Yunanto Arietama, George Armanda, Ferdio Aulia Nalar, Gusti Ayu Apriliani Ayu Dewi Pertiwi Ayu Septiana Azhari, Nazla Puteri Chyntia Devi, Made Putri Dastin Andre Dayana, Puteri Dayani, Nor Ella Debby Saputera, Debby Derlin, Ellanda Permata Desy Elisa Kismiliansari, Desy Elisa Devin, Firdi Dewi Nurdiana Dhian Ririn Lestari Dhian Ririn Lestari, Dhian Ririn Diah Puspita Rifasanti Dita Permatasari Dwi Nur Rachmah Dwi Nur Rachmah Edi Hartoyo Edi Hartoyo Edyson Edyson Edyson Edyson, Edyson Eka Yudha Rahman Erida Wydiamala Erwin Rosadi, Erwin Fachriyad, Muhammad Fahdyannoor, Fahdyannoor Fahmi, Yafi Farida Heriyani Farida Heriyani Farida Heriyani Farida Raudah, Farida Galuh Eka Suryani Hafizhah, Ghina Hardiyanti Ruslan Hayatun Nufus Hikmah Ika Darmayanta Husna Dharma Putera, Husna Dharma Ichrom Nahzi, Muhammad Yanuar Ihsanti, Shofia Hilwa Ihya Ridlo Nizomy, Ihya Ridlo Ikhwanda Angga L., Ikhwanda Angga Isnaini Isnaini Isnaini Isnaini Joharman Joharman Khatimah, Husnul Khatimah3, Husnul Lena Rosida Lie Vanny Leono Lutfia Papita Derizky Rahmayanti M. Rizki Valian Akbar, M. Rizki Valian Maharani Laillyza Apriasari Mohammad Bakhriansyah Muhammad Bayu Fernanda Muhammad, Fadil Muthmainah, Noor Nadhila Nadhila Nadya Azzahra, Nadya Nadya Salsabila Nafiah Syella, Nafiah Nafilah Syella, Nafilah Najiya Ulfa Nasution, Naulita Sari Nisa, Rohmatun Noor Rizka Yulia Rahmani Norma Sari Normaida Novianti Nur Qamariah Nurlaili Rafina Nurwafa, Nurwafa Pauline Surya Kurniati Prenggono, Muhamad Darwin Puspa Astri Sella Putra, Andifa Anugerah Putri Putri, Putri Qiptiah, Putri Mariatul Rahmah, Resvi Amalia Ridhoni, Muhammad Zaki S., Nur Almira R. Safaana, Aurora Savitri, Dwiana Siddik, Muhammad Baihaqi Silvan Juwita Siti Kaidah Sonya Esti Kholifa Sri Hayati Nufaliana, Sri Hayati Sri Widyarsi Strata Pertiwi, Strata Sukma Noor Akbar Talitha Maghfira Ramadhinta, Talitha Maghfira Thea Shagita Ulfa, Najiya Wahyuni A, Wahyuni Widya Nursantari Wydiamala, Erida Wydiamala, Erida Zafira Aisyah Putri Zohra, Noor Fathimah