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Journal : Bioinformatics and Biomedical Research Journal

Phenol Coefficient Test Combination Infusion of Cananga odorata – Averrhoa bilimbi L. Against Staphylococcus aureus and Salmonella typhi in Vitro Budiarti, Lia Yulia; Wydiamala, Erida; Ulfa, Najiya
Bioinformatics and Biomedical Research Journal Vol. 4 No. 1 (2021): Vol 4 No 1 (2021)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bbrj.04.01.03

Abstract

Cananga odorata (kenanga) flowers and Averrhoa bilimbi L. (belimbing wuluh) fruit are plant parts that contain relatively the same antibacterial compounds, namely flavonoids, saponins, and tannins. Both of these plants can be developed as an alternative natural antiseptic preparation, which is made in the form of a combination infusion. The effectiveness of an antiseptic preparation is measured by the coefficient value of the phenol antiseptic substance compared to 5% phenol against several standard test bacteria. This study aims to determine the antibacterial activity of the combination infusion of Cananga odorata flower - Averrhoa bilimbi L. fruit against Staphylococcus aureus ATCC 25923 and Salmonella typhi ATCC 19430 based on the in vitro phenol coefficient test. The phenol coefficient test method was carried out conventionally. The coefficient value close to 1 can be said that the antiseptic preparation has good activity and is equivalent to the phenol coefficient value as a comparison. The results showed that the mean coefficient of the phenol coefficient of the combination infusion of Cananga odorata flower - Averrhoa bilimbi L. fruit was 0.91 against S. aureus and 0.83 against S. typhi. The conclusion of this study, the antibacterial activity of the combination infusion of Cananga odorata flower - Averrhoa bilimbi L. fruit against Staphylococcus aureus obtained a higher phenol coefficient value than Salmonella typhi.
Antimicrobial Activity of Stenochlaena palustris and Sauropus androgynus in Staphylococcus aureus, Escherichia coli and Candidia albicans Budiarti, Lia Yulia; Isnaini, Isnaini; Dayana, Puteri; Sari, Norma; S., Nur Almira R.
Bioinformatics and Biomedical Research Journal Vol. 4 No. 1 (2021): Vol 4 No 1 (2021)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/bbrj.04.01.05

Abstract

Stenochlaena palustris and Sauropus androgynus are known to contains antimicrobial substances such as flavonoids, saponins and tannins compounds.The purpose of this study was to analyzes the antimicrobial activity of young and old leaf infusions of S. palustris and S. androgynus leaves against Staphylococcus aureus, Escherichia coli and Candida albicans. Analyze the antibacterial activity of a single preparations with a combination preparation of S.palustris (SP) and S.androgynus (SA) leaves infusion against S.aureus, E.coli and C.albicans. Leaves of S.palustris young part (SP1) taken 0-10 cm from shoots and old parts (SP2) 11-20 cm from shoots, while leaves of S.androgynus young part (SA1) leaves number 1 - 10 from the top and the old part (SA2) leaves number 11-20 from the top. The results showed that a single infusion of SP1 75% and SP2 75%, SA1 90% and SA2 90%, and a combination of SP1 75% and SA1 75%, SP2 75% and SA2 75% have the same activity as ampicillin in S.aureus. Single infusion of SP1 90% and SP2 90%, SA1 90% and SA2 90%, combination of SP1 75% and SA1 80% and the combination of SP2 80% and SA2 60% have the same activity as ciprofloxacin in E. coli. Single infusion of SP1 90% and SP2 90%, and a combination of SP1 80% and SA1 80%, SP2 80% and SA2 80% have the same activity as ketoconazole in C.albicans. The difference in activity due to differences in leaf parts used only occurred in E. coli, whereas in S.aureus and C.albicans (p <0.05).
Co-Authors A.A. Ketut Agung Cahyawan W Abdurahman Wahid Agung Biworo Agung Biworo Agung Biworo Ahdadia, Huda Aisyah Aisyah Akbar Rihansyah Akbar Rihansyah, Akbar Alfi Yasmina Alfi Yasmina Alfi Yasmina Alfia Fitriani Alfia Fitriani, Alfia Aliy Arivin Anward Alshazil, Renata Seikh Amalia, Maulidia Khairada Amalya, Khalida Zikra Amiratun Naillah Anward, Aliy Arivin Ari Yunanto Arietama, George Armanda, Ferdio Aulia Nalar, Gusti Ayu Apriliani Ayu Dewi Pertiwi Ayu Septiana Azhari, Nazla Puteri Bhisma Ridho Romadhon Borneo Yuda Pratama Chyntia Devi, Made Putri Dastin Andre Davi’ Qowiyul Ali Dayana, Puteri Dayani, Nor Ella Debby Saputera, Debby Derlin, Ellanda Permata Desy Elisa Kismiliansari Desy Elisa Kismiliansari, Desy Elisa Devin, Firdi Dewi Nurdiana Dewi, Arisanty Dhian Ririn Lestari Dhian Ririn Lestari, Dhian Ririn Diah Puspita Rifasanti Diah Puspita Rifasanti Dini Permata Sari Dita Permatasari Dita Permatasari Dwi Nur Rachmah Dwi Nur Rachmah Edi Hartoyo Edi Hartoyo Edyson Edyson Edyson Edyson Edyson Edyson, Edyson Eka Yudha Rahman Eka Yudha Rahman Erida Widyamala Erida Wydiamala Erida Wydiamala Erwin Rosadi Erwin Rosadi, Erwin Fachriyad, Muhammad Fahdyannoor, Fahdyannoor Fahdyanoor Fahmi, Yafi Farida Heriyani Farida Heriyani Farida Heriyani Farida Raudah Farida Raudah, Farida Ferdio Armanda Galuh Eka Suryani Ghina Salsabila Gusti Aulia Nalar Hafiz Rakhmatullah Hafizhah, Ghina Hardiyanti Ruslan Hayatun Nufus Herawati Herawati Hikmah Ika Darmayanta Husna Dharma Putera Husna Dharma Putera, Husna Dharma Husnul Khatimah Ichrom Nahzi, Muhammad Yanuar Ihsanti, Shofia Hilwa Ihya Ridlo Nizomy Ihya Ridlo Nizomy, Ihya Ridlo Ikhwanda Angga L. Ikhwanda Angga L., Ikhwanda Angga Indah Ramadhan Intan Kusuma Dewi Irma Zufira Isnaini Isnaini Isnaini Joharman Joharman Khatimah, Husnul Khatimah3, Husnul Lena Rosida Lie Vanny Leono Lutfia Papita Derizky Rahmayanti M. Rizki Valian Akbar M. Rizki Valian Akbar, M. Rizki Valian M. Yogi Riyantama Isjoni Maharani Laillyza Apriasari Moehammad Rezaldi Panesa Mohammad Bakhriansyah Muhammad Baihaqi Siddik Muhammad Bayu Fernanda Muhammad, Fadil Muthmainah, Noor Nadhila Nadhila Nadya Azzahra, Nadya Nadya Salsabila Nafiah Syella, Nafiah Nafilah Syella Nafilah Syella, Nafilah Najiya Ulfa Nasution, Naulita Sari Nazla Puteri Azhari Nida Nurkhalishah Nisa, Rohmatun Noor Fathimah Zohra Noormuthmainah, Noormuthmainah Nor Admi Zayanti Nor Ella Ella Dayani Norma Sari Normaida Novianti Novita Pratiwi Nur Adnia Nur Azmina Aisyah Nur Qamariah Nur Salsabila Apriliani Risma Putri Nurlaili Rafina Nurwafa, Nurwafa Nurzahida, Gusti Nadya Pauline Surya Kurniati Prenggono, Muhamad Darwin Puspa Astri Sella Putra, Andifa Anugerah Putri Putri, Putri Qiptiah, Putri Mariatul Rahmah, Resvi Amalia Rahmiati Rahmiati Raymona Dewi Ginarti Ridhoni, Muhammad Zaki Rohmatun Nisa S., Nur Almira R. Safaana, Aurora Savitri, Dwiana Shahiba Inayati Maghfira Siddik, Muhammad Baihaqi Silvan Juwita Siti Kaidah Siti Kaidah Solly Aryza Sonya Esti Kholifa Sri Hayati Nufaliana Sri Hayati Nufaliana, Sri Hayati Sri Widyarsi Strata Pertiwi Strata Pertiwi, Strata Sukma Noor Akbar Talitha Maghfira Ramadhinta Talitha Maghfira Ramadhinta, Talitha Maghfira Thea Shagita Ulfa, Najiya Vania Puspitasari Sangadi Wahyuni A Wahyuni A, Wahyuni Widiantoro Saputro Widya Nursantari Wydiamala, Erida Wydiamala, Erida Yudi Yahya Yulia, Noor Zafira Aisyah Putri Zohra, Noor Fathimah Zufira, Irma