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Budiyanto Budiyanto
Universitas Bengkulu
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Social Sciences Other

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EKSTRAK BATANG “AKAR KAIK-KAIK” ( Uncaria Cordata Lour. ) Merr SEBAGAI ANTIDIABETES PADA MENCIT YANG DI INDUKSI ALOKSAN Kirent Arikhsa Putri; Nurhamidah; Agus Sundaryono
ALOTROP Vol. 9 No. 1 (2025): Jurnal Pendidikan dan Ilmu Kimia
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v9i1.42208

Abstract

[EXTRACT OF “KAIK-KAIK ROOT” STEM (Uncaria Cordata Lour.) Merr AS AN ANTIDIABETES IN ALLOXAN-INDUCED MICE] This research aims to determine the effect of giving kaik-kaik root stem extract (Uncaria cordata Lour. Merr) on the blood sugar levels of mice (Mus musculus) induced by alloxan. This reseacrh began with a phytochemical test conducted to determine the secondary metabolite compounds contained in the root stem of kaik-kaik (Uncaria cordata Lour. Merr). Extraction is done by maceration method. Antidiabetic activity test was carried out on male mice induced by alloxan. The results of the phytochemical test showed that the stem extract of Uncaria cordata contained alkaloids, flavonoids, tannins, saponins and terpenoids. The results of the antidiabetic activity test showed that the Uncaria cordata stem extract was able to reduce blood glucose levels in alloxan-induced mice with the optimal dose of Uncaria cordata stem extract at a dose of 0.043 g/kgBB. Based on the results of this study, it can be concluded that the stem of Uncaria cordata has antidiabetic activity. Keywords: Antidiabetic, Kaik-Kaik Root Stem, Uncaria cordata Lour. Merr, Alloxan
Pengaruh Pemberian Nanopartikel Kitosan - Ekstrak Batang J. multifida L terhadap Jumlah Eritrosit M. musculus yang Teriinfeksi P. berghei Listiono, Arsela Eko; Firdaus, M. Lutfi; Sundaryono, Agus
BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains Vol. 8 No. 6 (2025): BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/be7vbx11

Abstract

This study aimed to determine the effect of administering chitosan nanoparticles loaded with Jatropha multifida L. stem extract on the erythrocyte count of Mus musculus infected with Plasmodium berghei as well as their characterization results. The method used was the preparation of chitosan nanoparticles loaded with J. multifida L. stem extract using the ionic gelation method. Characterization results using Particle Size Analysis (PSA) showed that the chitosan nanoparticles loaded with J. multifida L. stem extract had an average particle size of 567.12 nm with a polydispersity index (PDI) value of 0.11, while characterization using X-ray diffraction (XRD) showed the highest peak at a 2θ angle of 28.68°. The results indicated differences in the effects of varying concentrations of chitosan nanoparticles loaded with J. multifida L. stem extract on erythrocyte counts. The conclusion of this study is that the most effective dose of chitosan nanoparticles loaded with J. multifida L. stem extract was 0.028 g/kg body weight, followed by the administration of crude J. multifida L. stem extract at the same dose.   Keywords: Erythrocytes, Jatropha multifida L., Chitosan, Nanoparticles, Particle Size Analysis, Plasmodium berghei, X-ray Diffraction
Co-Authors ACENG RUYANI Ade Indriani Putri Alfia Novera Indah Esa Kasih Arina Fatharani Arsela Eko Listiono Bedah Rupaedah Bedah Rupaedah, Bedah Bhakti Karyadi BHAKTI KARYADI Bhakti Karyadi Bonodikun Bonodikun Candrawati, Emilia Candrawati, Emilia Chyntia Margareta Cici Romayanti Dapot Parulian Manurung Devi Silsia Dewi Handayani Dhea Prasiwi Dian Kartika Sari Eko Swistoro Elvinawati Elvinawati Emi Hartati Emilia Candrawati Emilia Candrawati Endang Widi Winarni Endang Widi Winarni Ernis, Gustria Fahrurrozi, Fahrurrozi Fenny Andriani Fitri Yuwita Fuji Ramadenti Hadi Apriyoanda Hadi Apriyonda Henny Johan Herison, Catur Hermansyah Amir I Nyoman Candra I Nyoman Chandra Ilham Agus Saputra Jertadi Putri Dhani Kirent Arikhsa Putri Krisandini, Triana Lina Widawati M Lutfi Firdaus M. Farid M. Lutfi Firdaus M. Lutfi Firdaus M. Lutfi Firdaus, M. Lutfi Maya Wahyunarti Mayshah Purnamasari Megasari Megasari Meizul Zuki Mellyta Uliyadari Mina Sihite Hutasoit Muchammad Farid Mukhsin Mukhsin Muzanip Alperi Nur Wakidatul Khasanah Nurhamidah Nurhamidah Nurhamidah Nurhamidah Nurhamidah Nurhamidah Nurleli Nurleli Nurlia Latifah Nursaadah, Euis Pandu Imam Sudibyo Adib Pandu Imam Sudibyo Adib Pramesthi Regita Putri Putri Suci Asriani Rantika Khumairah Rasie Janika Reni Jumika Ridwan Yahya Rika Partika Sari Rina Elvia Rina Elvia Rina Elvia, Rina Rina Endriani Ririn Trinanda Rofiqa Asri Sari Puspita Ningsih Shiba Meike Indira Shinta Lestari Sipriyadi Sri Astuti Sumpono Sumpono Sumpono Sumpono Sumpono, Sumpono Suryadi Suryadi Theo Kuntara Tuti Maryana Tyas Sri Muryati Ulfah Anis Umaya Umi kalsum Wuri Marsigit Yenni Okfrianti Yohannes Adimar Marbun Yulia Suparti Zulman Efendi