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All Journal Biology, Medicine, & Natural Product Chemistry PERENNIAL ULIN: Jurnal Hutan Tropis Buletin LOUPE (Laporan Umum Penelitian) Buletin Poltanesa Jurnal Agriment Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Jurnal Sains dan Kesehatan ABDIKU : Jurnal Pengabdian Masyarakat Universitas Mulawarman
Sari, Nur Maulida
Politeknik Pertanian Negeri Samarinda
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : PERENNIAL

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AKTIVITAS ANTIOKSIDAN DAN ANTIBAKTERI BAGIAN RANTING DAN BATANG TUMBUHAN KARAMUNTING (Melastoma malabathricum): Antioxidant and Antibacterial Activity of The Twigs and Stem Bark of Karamunting Plants (Melastoma malabathricum) Nur Maulida Sari; Irawan Wijaya Kusuma; Rudianto Amirta; Nur Indriana Fitriah
PERENNIAL Vol. 17 No. 2 (2021): Vol. 17 No. 2, Oktober 2021
Publisher : Forestry Faculty of Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24259/perennial.v17i2.14547

Abstract

East Kalimantan is one of the areas that have the potential for various traditional medicinal plants. Melastoma malabathricum (known locally as karamunting, senduduk) is an invasive plant in the family of Melastomataceae with a potential medicinal plant. This study explored the potential of twigs and stem bark of Karamunting (Melastoma malabathricum) for its antioxidant and antibacterial activity. The twigs and stem bark of Karamunting were macerated to yield ethanolic extract. The phytochemical screening was evaluated by Harborne and Kokate methods. Antioxidant activity was evaluated by DPPH radical scavenging assay. Antibacterial activity was examined using agar well diffusion method against Propionibacterium acnes. The results showed that the ethanol extracts of twigs and stem bark samples display an ability to inhibit DPPH free radical by 82% and 88% at 50 ppm concentration. Antibacterial activity of the twigs and stem bark samples showed potent activity to inhibit the P. acnes growth with 11.3 mm and 11 mm inhibition activity. Based on the results, the twigs and stem bark of M. malabathricum plants display potential as a natural antioxidant and antibacterial agent.
ANALISIS FITOKIMIA, AKTIVITAS ANTIOKSIDAN DAN ANTIBAKTERI DAUN ANDONG (Cordyline fruticosa) Andani, Lowisesi; Sari, Nur Maulida; Salusu, Heriad Daud; Yusdiansyah; Wartomo; Prayitno, Joko; Aryani, Farida
PERENNIAL Vol 18 No 2 (2022): Vol. 18 No. 2, Oktober 2022
Publisher : Forestry Faculty of Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24259/perennial.v18i2.22466

Abstract

The Andong Merah plant (Cordyline fruticosa) is known to have natural antibacterial properties, which can inhibit the growth of cancer and tumors. Several studies that have been carried out previously showed the potential of red Andong Merah plant extracts for health, especially in the Andong Merah leaves with many active compounds. This study explored the potential of Andong Merah leaves for their phytochemical analysis, antioxidant and antibacterial activity. Andong Merah leaves were macerated using n-hexane, ethyl acetate, and ethanol solvent to yield the crude extracts. The phytochemical analysis was evaluated by the Harborne and Kokate method. Antioxidant activity was evaluated by DPPH radical scavenging assay. Antibacterial activity was examined using the agar well diffusion method against Propionibacterium acnes, Streptococcus mutans, and Streptococcus sobrinus. The results showed that the Andong Merah leaves extract contains alkaloids, flavonoids, tannins, steroids, and saponins. The antioxidant activity test showed that the n-hexane and ethyl acetate of Andong Merah leaves extracts displayed the ability to inhibit DPPH free radical by 74% and 75% at 200 ppm concentration, while ethanol extracts by 79% at 100 ppm concentration. The antibacterial activity showed that the ethanol extract of Andong Merah leaves displayed the ability to inhibit the Propionibacterium acnes growth with 12 mm inhibition activity at 400 µg. The ethanol and ethyl acetate of Andong Merah leaves extract can inhibit the Streptococcus mutans growth with 9 mm at 400 µg. Antibacterial activity of n-hexane, ethyl acetate, and ethanol extract of Andong Merah leaves display the ability to inhibit the Streptococcus sobrinus growth with 10 mm at 400 µg concentration. Based on the results, Andong Merah leaves (Cordyline fruticosa) display potential as a natural antioxidant and antibacterial agent.
Co-Authors Abdul Rasyid Zarta Abdul Rasyid Zarta Ahmad Zamroni Alfrida Andani, Lowisesi Andi Lisnawati Andi Yusuf Andriany, Riri Aprilianus Robert Lau Arensyah, Mardy Astuti, Reni Puji Aziza, Humairo Balfasd, Aulia Lutfi Dedy Cahyadi, Dedy Devita Sari , Elfani Dwinita Aquastini Erna Rositah Eva Nurmarini Farida Aryani Farida Aryani Farida Aryani Hanifah, Nisrina Putri Heriad Daud Salusu Hertianti, Erina Ida Maratul Khamidah Indah Fitri Astuti, Indah Fitri Irawan Wijaya Kusuma, Irawan Wijaya Isyati Rahimah , Nurin Ita Merni Patulak Ita Merni Patulak Jasmawati, Jasmawati JOKO PRAYITNO Kerawing, Rosalinda Khoirunnita, Aulia Kridalaksana, Awang Kutana, Agung Nugrawan Lisnawati, Andi Lumbanraja, Gabriel Permadi Lumbantobing, Hizkia Marulitua Mentari Ameliana Mika Debora Br Barus Misnah Wati Muhammad Fikri Hernandi Muis, Puspitasari Murdianto Murdianto, Murdianto Ngapiyatun, Sri Nona, Risna Nur Indriana Fitriah Nur Indriana Fitriah Nurhamidah Nurmarini, Eva Paurru, Periani Pelawi, Herdinta Jandri Periani Paurru Pragaloka, Nur Indah Purba, Ignasius Wardi Saputra Ramadhan, Mohammad Ridho Rasni Alex Riri Andriany Rositah, Erna Rudi Djatmiko Rudianto Amirta Rudito Rudito Salusu, Heriad Daud Siti Raihanah Suryadi Syauqi, Anis Vania Azhara Waldini Wahyuningtyas, Irma Waldini, Vania Azhara Wartomo Wartomo Wartomo, Wartomo Yusdiansyah Yusuf, Andi Zamroni, Ahmad Zarta, Abdul Rasyid