Article Per Year (5 Year)
p-Index From 2020 - 2025
3.018
P-Index
This Author published in this journals
All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Kedokteran Brawijaya Majalah Kesehatan FKUB Medical Laboratory Technology Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Bioscientia Medicina : Journal of Biomedicine and Translational Research MMJ (Mahakam Midwifery Journal) Journal of Issues in Midwifery Jurnal Aisyah : Jurnal Ilmu Kesehatan Bioscientia Medicina : Journal of Biomedicine and Translational Research Malang Respiratory Journal Jurnal Klinik dan Riset Kesehatan Zona Kebidanan : Program Studi Kebidanan Universitas Batam
Eviana Norahmawati
Department Of Anatomic Pathology, Faculty Of Medicine, Brawijaya University, Malang, East Java
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

Published : 29 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : MMJ (Mahakam Midwifery Journal)

 1 
PENGARUH EKSTRAK MASERASI TEH HIJAU TERHADAP APOPTOSIS SEL GRANULOSA FOLIKEL OVARIUM PADA RATTUS NORVEGICUS YANG DIPAJAN MSG Endah Wijayanti; Tatit Nurseta; Eviana Norahmawati
MMJ (Mahakam Midwifery Journal) Vol 4 No 1 (2019): Volume 4 No. 1 Mei 2019
Publisher : Politeknik Kesehatan Kementerian Kesehatan Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (510.154 KB) | DOI: 10.35963/midwifery.v4i1.121

Abstract

Abstract Monosodium glutamate is one of the additives used a food flavoring and is widely known by society. The consumption of MSG in large quantities leads to the lesions of the hypothalamus nucleus, leading to some changes in the reproductive system. The aim of this study is to find out the influence of green tea extract against Apoptosis cells Granulose ovarian follicle Rattus norvegicus Dipajan MSG. The research method of using a true experimental research approach post test only control group Design. The sample used was a female white rat (Rattus norvegicus) the number of 25 tails divided into 5 groups. Exposure of monosodium glutamate administered at a dose of 0.7 mg/grBB per oral and green tea extract a variety of doses administered 2 hours thereafter during 30 days after the rats were obtained in the Proestrus phase. Apoptosis examination uses In Situ Cell Death Detection Kit, POD catalog number 11684817910 of Roche brand with Tunnel method. Data were analyzed using the One Way ANOVA test. Results showed that the lowest average apoptosis rate was seen in the MSG Administration treatment group and green tea extract dose 1.4 mg/tail/day (18,686 ± 2,247) but increased again on the group's MSG administration treatment and green tea extract dose 2.8 mg/tail/day (23,752 ± 3,206). So the administration of green tea extract of varying doses can decrease apoptosis in the Rattus norvegicus that is Dipajan MSG. Keywords: green tea extract, monosodium glutamat, Apoptosis Abstrak Monosodium glutamat, merupakan salah satu zat aditif yang digunakan sebagai penyedap makanan dan dikenal secara luas oleh masyarakat. Konsumsi MSG dalam jumlah besar menyebabkan lesi bagian nucleus arkuata hipotalamus sehingga menimbulkan beberapa perubahan pada sistem reproduksi. Tujuan dalam penelitian ini untuk mengetahui pengaruh ekstrak teh hijau terhadap Apoptosis Sel Granulosa Folikel Ovarium Rattus norvegicus yang dipajan MSG. Metode Penelitian menggunakan penelitian true eksperimental pendekatan post test only control group design. Sampel yang digunakan adalah tikus putih betina (Rattus norvegicus) sejumlah 25 ekor yang terbagi menjadi 5 kelompok. Paparan monosodium glutamat diberikan dengan dosis 0,7 mg/grBB per oral dan ekstrak teh hijau berbagai dosis diberikan 2 jam setelahnya selama 30 hari setelah didapatkan tikus berada pada fase proestrus. Pemeriksaan Apoptosis menggunakan In Situ Cell Death Detection Kit, POD nomor katalog 11684817910 merk Roche dengan metode Tunel. Data dianalisis menggunakan uji One Way Anova. Hasil penelitian menunjukkan bahwa Nilai rerata apoptosis terendah tampak pada kelompok perlakuan pemberian MSG dan ekstrak teh hijau dosis 1,4 mg/ekor/hari (18.686± 2.247) namun meningkat lagi pada kelompok perlakuan pemberian MSG dan ekstrak teh hijau dosis 2,8 mg/ekor/hari (23.752± 3.206). Sehingga pemberian ekstrak teh hijau berbagai dosis dapat menurunkan apoptosis pada Rattus norvegicus yang dipajan MSG Kata Kunci : ekstrak teh hijau, monosodium glutamat, dan Apoptosis
Co-Authors A.A. Ketut Agung Cahyawan W Adilah Ulfiati Adilah Ulfiati, Adilah Agil Dananjaya Aina Angelina Ainun Ganisia Aliesya Patricia Amalia Pradanti Widarso, Amalia Pradanti Ardhian Wardana Ardhian Wardana, Ardhian Aris Rosidah Dian Sutarini, Ni Luh Gede Didiek Darmadi Ts Dwi Yuni Nur Hidayati Ega Prosfera, Rahma Haryunita Elisa Danik Kurniawati Endah Wijayanti Erawati, Dini Ervina, Rita Fadli, Muhammad Luqman Fitriana Nugraheni Fitriana Nugraheni, Fitriana Frenty Hadiningsih, Eka Hamka Muhammad Nasir Laitupa Harun Al Rasyid Harun Al Rasyid Herpan Syafii Harahap Ihda Dian Kusuma Ineke Permatasari Irmansyah, Istan Irsan, Istan Irmansyah Isharanto, Artono Kenty Wantri Anita, Kenty Wantri Kurnia Penta Seputra Laitupa, Hamka Muhammad Nasir Loeki Enggar Fitri lumban gaol, andy MIFTAHUL JANNAH Miftahul Jannah Mochammad Dalhar Nabila, Astrid Hanan Nanik Setijowati Ni Putu Sri Haryati Noorhamdani Nur Fahma Pradiptasari Nur Fahma Pradiptasari, Nur Fahma Nurdiana Nurdiana Pratista Adi Krisna, Pratista Adi Pratiwi, Suryanti Dwi Putra, Ngakan Putra, Ngakan Putu Putri Ardela, Mayasari RA Rose Khasana Dewi Rachmad Sarwo Bekti Rahmana, Rahima Azzahra Retnani, Diah Prabawati Retty Ratnawati Ririn Handayani Rose Dewi Sawitri, Lia Setyawan, Ungky Sri Winarsih Sujarot Dwi Sasmito sujarot dwi sasmito, sujarot dwi SURYANTI Tanti Tri Lestary Tatit Nurseta Teguh Prihanto Teguh Wahju Sardjono Teguh Wahju Sardjono Tinny Endang Endang H Ulfaningtyas, Kiki Wati, Linda Ratna Wiyasa, I Wayan Arsana Yahya Irwanto Yudhanto, Hendy Setyo Zakiyah Zulaifa Zakiyah Zulaifa, Zakiyah