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Quality of Life and Costs of Illness of Dengue Patients at Pku Muhammadiyah Yogyakarta and Bantul Boisi, Cici Feronika; Purwanto, Barkah Djaka; Supadmi, Woro; Faridah, Imaniar Noor; Perwitasari, Dyah Aryani
Jurnal Ilmiah Farmasi Vol. 20 No. 2 (2024): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol20.iss2.art5

Abstract

Background: The manifestation of dengue is a decrease in hematocrit and platelet levels, leading to a decrease in the patient’s quality of life and having an impact on the patient’s medical costs.Objective: This study objective was to ascertain the quality of life and medical costs associated with dengue patients.Method: This study employed a cross-sectional design at PKU Muhammadiyah Hospitals in Bantul and Yogyakarta from January to August in 2023. Pediatric patients’ quality of life was assessed using the EQ-5D-Y questionnaire, while adult patients’ using the EQ-5D-5L questionnaire. Data on patients’ medical costs was obtained from the hospital's financial database. The data were then analyzed descriptively and presented as a percentage of quality of life and average medical costs.Results: The results showed that pediatric DF patients in both hospitals reported anxiety and depression, with percentages of 100% (Yogyakarta) and 75% (Bantul), respectively. Meanwhile, most adult DF patients experienced problems in carrying out routines, 71.4% (Yogyakarta) and 50% (Bantul), respectively. Adult DHF patients in both hospitals reported pain and discomfort of 66.7% (Yogyakarta) and 100% (Bantul), respectively. The highest average medical costs paid by DF and DHF patients at PKU Jogja Hospital were IDR 4,919,450 and IDR 6,981,500. DF and DHF patients at PKU Hospital with BPJS insurance, with the highest average medical costs of IDR 2,726,245.5 (for DF patients) and IDR 4,797,700 (for DHF patients) to cover for laboratory costs.Conclusion: Dengue fever infections are impacting the patient's quality of life and medical costs.
The validation of patient knowledge questionnaire for patients with diabetes mellitus and hyperlipidemia Saputri, Ginanjar Zukhruf; Dania, Haafizah; Faridah, Imaniar Noor; A, Faiza Chusnuni
Pharmaciana Vol. 8 No. 2 (2018): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v8i2.7508

Abstract

Prevalence of Diabetes Mellitus (DM) with Hyperlipidemia increased in Indonesia, where both diseases have a risk of complications towards cardiovascular disease. DM patients with hyperlipidemia require proper management to control blood sugar, total cholesterol and LDL cholesterol. Knowledge is one of the important factors in improving adherence therapy and quality of life of DM-hyperlipidemia patients, especially in controlling blood glucose level and total cholesterol levels. This study aims to develop a patient questionnaire of DM-hyperlipidemia.The study used cross sectional method. Inclusion criteria were patients aged 18 – 70 years old, diagnosed DM-Hyperlipidemia, getting at least 1 oral antidiabetic and oral anti-cholesterol. The questionnaire item of knowledge was developed based on gudeline therapy and previous research reference. Expert validation is done on Doctor who had expert in DM and clinical psychologist. The pilot test was performed on 10 healthy patients and 10 patients of DM-hyperlipidemia who had eligible inclusion criteria. Validation of questionnaire was done on 30 patients of DM-Hyperlipidemia who undergoing therapy at outpatient clinic of PKU Muhammadiyah Hospital Yogyakarta. Data collection was done by interviewing questionnaires in patients. Analysis of data using SPSS with product moment validation test and cronbach alpha to see the reliability of questionnaire.Validation results show there are some invalid items that are in questions 9, 11, 12, 15, 16 and 17, the range of questions about knowledge about hyperlipidemia, medication and general health. Re-validation without invalid item was done and obtained value r> 0.3, with value of Cronbach alpha 0,715.The DM-Hyperlipidemia patient questionnaire was valid and reliable to measure the level of knowledge of DM patients with Dysipidemia.  
Penggunaan Herbal Balm Aromaterapi Essential Oil Bunga Lavender Sebagai Pencegahan Insomnia Usia Produktif di Universitas Aisyiyah Yogkakarta : Indonesia Faridah, Imaniar Noor; Pertiwi, Deasy Vanda; Hipmi, Ahmad Fahrian; Maulizah, Rizlah; Rahmawati, Sri
Jurnal Abdimas Madani dan Lestari (JAMALI) Volume 07, Issue 01, Maret 2025
Publisher : UII

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jamali.vol7.iss1.art10

Abstract

One of the basic human needs is sleep, every individual definitely needs enough sleep between 6-9 hours a day. The benefits you get from getting enough sleep include maintaining stamina and health. According to the World Health Organization (WHO), in Indonesia in 2020 around 10%, which means approximately 28 million of the totals 238 million Indonesian population suffer from insomnia. Insomnia is a symptom of difficulty sleeping which is usually caused by bad behavior or habits before bed. In general, teenagers often experience insomnia due to consuming too much caffeine (coffee). The aim of this empowerment program activity is to provide more knowledge regarding insomnia and making lavender essential oil aromatherapy balm to help reduce insomnia that occurs among students, especially at Aisyiyah University, Yogyakarta, as well as increasing student creativity. in entrepreneurship. The implementation method was carried out by counseling about insomnia and the practice of making aromatherapy balm as an alternative treatment for insomnia at Aisyiyah University, Yogyakarta. Making aromatherapy balm preparations using an inhalation mechanism is very effective and easy to apply while traveling. The results of data analysis from giving questionnaires to students regarding insomnia knowledge showed that the score at the pretest was 50% (poor category), and the posttest had a score of 76.8% (good category). The results of this analysis showed that there was a significant difference in scores before and after giving the counseling. insomnia in productive age at Aisyiyah University Yogyakarta. Aromatherapy balm therapy as an alternative to reduce insomnia. Lavender aroma therapy contains linalool acetate which is able to relax and relax the nervous system and tense muscles by increasing the frequency of alpha waves and this condition is associated with treating insomnia.
Effect of Gene Polymorphisms on Oral Antidiabetic Drug Response in Patients With Type 2 Diabetes Mellitus Hidayati, Nur Rahmi; Perwitasari, Dyah Aryani; Faridah, Imaniar Noor; Susilo, Rinto
Sciences of Pharmacy Volume 4 Issue 2
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0402321

Abstract

Diabetes mellitus is currently one of the global health threats. The prevalence and incidence of this disease continue to increase, both in industrialised and developing countries, including Indonesia. There are different types of DM marker gene polymorphisms in each racial group. These genetic variations contribute to the response of oral antidiabetic drugs. This article aims to conduct a narrative review of the influence of gene polymorphisms on oral antidiabetic drug response in patients with type 2 diabetes mellitus. Article searches were conducted in PubMed, Scopus, Google Scholar, and Wiley published from 2014 to 2024. From the screening, 30 articles met the criteria. The articles reported various gene polymorphisms associated with the efficacy of oral antidiabetic therapy in patients with type 2 diabetes mellitus. In patients with type 2 diabetes mellitus with certain gene variations, there was no significant decrease in HbA1c values after taking medication. Gene polymorphisms may affect the pharmacokinetics of oral antidiabetics and therapeutic response in patients with type 2 diabetes.
Antiemetic prophylaxis utilization in cancer patients in a hospital in Yogyakarta Special Region Faridah, Imaniar Noor; Dyah Aryani Perwitasari; Siswandi; Lamhot B Simanjuntak; Suhendra, Gugun; Wulandari, Dewi; Dania, Haafizah; Rizky, Muhammad Arif; Islami, Safira Nur; Fatimah, Salma Auliya
Indonesian Journal of Pharmacology and Therapy Vol 5 No 3 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.14243

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Chemotherapy is a type cancer treatment that uses anticancer drugs to inhibit cell division and kill cancer cells. Chemotherapy can cause side effect due to normal cells damages. The study aimed to investigate the use of antiemetic prophylaxis as premedication to prevent or reduce side effects on cancer patients undergoing chemotherapy. It was a observational study with retrospective design using medical records data of cancer patients who underwent chemotherapy in a hospital in Yogyakarta Special Region during May – September 2022. The results showed the cancer patients were dominated by women (85.71%) with ages 46-65 yr (63.27%) and stage III cancer (87.76%). There were 18 types of anticancer drugs and the most widely used drugs were doxorubicin 60 mg for the moderate emetogenic category and vinorelbine 37.5 mg for the low emetogenic category. The most widely used premedication regimen was a combination granisetron 3 mg, ondansetron 8 mg, and dexamethasone 10 mg regimen (72.45%). This combination was most often used for the cancer patients with the moderate emetogenic category (39 patients or 49.4%). However, not all the cancer patients undergoing chemotherapy with the low and moderate emetogenic anticancer drugs were administered the premedication. In conclusion, doxorubicin and vinorelbine are the most widely used for cancer patients undergoing chemotherapy in the hospital. In addition, a combination of granisetron, ondansetron, and dexamethasone is widely used as premedication.
EVALUATION OF PROPHYLACTIC ANTIBIOTIC USE IN SURGICAL PATIENTS USING THE GYSSENS METHOD AT A PRIVATE HOSPITAL IN YOGYAKARTA Arviani, Septania Dini; Faridah, Imaniar Noor; Amsriza, Fadli Robbi
Jurnal Farmasi Sains dan Praktis Vol 11 No 3 (September-December 2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v11i3.12994

Abstract

Prophylactic antibiotics are used before, during, and up to 24 hours after surgery, and can be administered to patients 30-60 minutes before surgery, must adhere to the principle of “Right Antibiotics”. This study aims to assess the application of prophylactic antibiotics in surgical patients in a private hospital in Yogyakarta to promote rational antibiotic use. This study is quantitative and non-experimental. Data were collected prospectively over a period of 30 days from August 4 to September 4, 2024. The study sample consisted of all surgical patients who received prophylactic antibiotics. Prophylactic antibiotic data were analyzed using the Gyssens method. Out of the data collected, 110 patients received preventive antibiotics, and 97 of these patients met the inclusion criteria. Patient characteristics predominantly included a 46% incidence of cesarean sections. Prophylaxis employed three antibiotics, viz. ceftriaxone in 78 patients (79.38%), cefazolin in 19 patients (19.59%), and cefotaxime in 1 patient (1.03%). The assessment utilizing the Gyssens approach revealed that 31 patients were classified into category V (no indication), 49 patients into category IVA (more effective antibiotics available), and one patient into category I (not suitable during prophylaxis). Sixteen patients in category 0 were included in the reasonable antibiotic regimen. This study states that most antibiotics are not in accordance with the Guidelines for Antibiotic Use established by the Ministry of Health of the Republic of Indonesia in 2021.
Kualitas Hidup Mahasiswa Profesi Apoteker Dengan Health Related Quality Of Life (HRQOL) SF-6D Di Fakultas Farmasi Universitas Ahmad Dahlan Yogyakarta Hidayati, Ana; Mufliha, Farida Nur; Faridah, Imaniar Noor
Media Farmasi: Jurnal Ilmu Farmasi Vol. 13 No. 1: Maret 2016
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v13i1.5748

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Kualitas hidup individu dipengaruhi oleh status kesehatannya masing-masing. Individu sehat maupun sakit dapat diukur kualitas hidupnya. Pengukuran menggunakan instrumen Short Form 36 (SF-36). Penelitian bertujuan untuk mengetahui nilai kualitas hidup dan faktor-faktor yang mempengaruhi kualitas hidup mahasiswa. Penelitian ini menggunakan rancangan crossectional. Sampel merupakan mahasiswa Program Studi Profesi Apoteker angkatan XXXI di Fakultas Farmasi Universitas Ahmad Dahlan yang diberi kuesioner SF-36 dan form karakteristik sampel. Analisis untuk SF-36 dipetakan ke SF-6D dan data karakteristik dinyatakan dalam presentase. Analisis hubungan antara karakteristik sampel dengan kualitas hidup dilakukan dengan Uji Mann-Whitney dan Kruskal-Wallis.            Jumlah subyek yang digunakan pada penelitian berjumlah 126 mahasiswa. Hasil kualitas hidup mahasiswa profesi apoteker pada SF-6D menunjukkan skor sebesar 0,739. Hasil uji antara skor kualitas hidup dengan karakteristik menunjukkan adanya hubungan dengan kualitas hidup pada jenis transportasi ( p=0,039 ) dan riwayat penyakit ( p=0,01 ).          Berdasarkan hasil penelitian dapat disimpulkan bahwa skor  kualitas hidup mahasiswa dari SF Indeks pada SF-6D yaitu 0,739. Faktor yang mempengaruhi kualitas hidup mahasiswa adalah transportasi dan riwayat penyakit.           Kata kunci : kualitas hidup, mahasiswa profesi apoteker, SF-36, SF-6D
Quality of life of dengue patients in Panembahan Senopati regional general hospital Wigatiningtyas, Ariska; Perwitasari, Dyah Aryani; Faridah, Imaniar Noor; Dania, Haafizah; Supadmi, Woro
Media Farmasi: Jurnal Ilmu Farmasi Vol. 19 No. 2: September 2022
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v19i2.22509

Abstract

Yogyakarta is one of the top 10 cities with the highest number of dengue cases in Indonesia. One of the reasons for this is the lack of knowledge about the dengue virus in the community. To find out the quality of life of dengue patients in the Bantul Penembahan Senopati Public Hospital.This research uses the descriptive method with a cross-sectional design. The sampling technique utilized was the purposive sampling method. 18 research subjects were chosen as the sample with an inclusion criteria of patients undergoing inpatient treatment and aged > 4 years of age. This study used the EQ-5D-5L and EQ-5D-Y.The quality of life of 70% of the adult patients experienced pain of EQ-VAS 67 ± 17.191, while all child patients experienced pain of EQ-VAS 54.375 ± 11.783. The quality of life of dengue patients was measured with the EQ-5D-5L for adults and EQ-5D-Y for children and obtained a poor score due to a decrease in the dimension of pain felt and the usual activities done such as working, studying, and playing.
Integration of genomic databases and bioinformatic approach to identify genomic variants for sjogren’s syndrome on multiple continents Puspitaningrum, Anisa Nova; Perwitasari, Dyah Aryani; Adikusuma, Wirawan; Djalilah, Gina Noor; Dania, Haafizah; Maliza, Rita; Faridah, Imaniar Noor; Sarasmita, Made Ary; Rezadhini, Melodia; Cheung, Rocky; Irham, Lalu Muhammad
Media Farmasi: Jurnal Ilmu Farmasi Vol. 19 No. 2: September 2022
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v19i2.23706

Abstract

An autoimmune disorder is an abnormality that causes a disease. It is caused by a weakened immune system. One of the autoimmune diseases is Sjogren’s syndrome, which affects the salivary and lacrimal glands and causes dry mouth, dry eyes, and dry skin. Sjogren’s syndrome influences humans of every age, with the symptoms occurring at the age of 45–55 years and rarely in children. One of the factors causing Sjogren’s syndrome is genetic disorders. To identify genes that can influence Sjogren’s syndrome in this study, we used several databases, including GWAS Catalog, HaploReg Version 4.1, GTEX portal, and Ensembl, particularly to identify the gene expression profiles of TNIP1, TNFAIP3, and IRF5 and the quantitative properties of locus’ expression. This research showed that the missense variants and splice donor rs2233290, rs2230926, and rs2004640 influenced the susceptibility of autoimmune diseases, especially Sjogren’s syndrome, in the fibroblast tissue, sigmoid tissue, sigmoid colon, skin, esophagus, and adrenal glands. The allele frequency of each variant was then assessed in African, American, European, and Asian populations. Our data showed that TNIP1, TNFAIP3, and IRF5 genes in African and American populations had higher frequencies than in the Asian population. This implies that the last of the aforementioned populations might be relatively susceptible to the autoimmune disease Sjogren’s syndrome.
The quality of life of hemodialysis patients in Yogyakarta, Indonesia Siswandi, Siswandi; Perwitasari, Dyah Aryani; B Simanjuntak, Lamhot; Suhendra, Gugun; Wulandari, Dewi; Dania, Haafizah; Faridah, Imaniar Noor; Adnan, Adnan
Pharmaciana Vol. 14 No. 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.28449

Abstract

The assessment of quality of life serves as a critical evaluation of the effectiveness of the administered hemodialysis treatment. The measurement of quality of life can be conducted using the Kidney Disease Quality of Life Short Form (KDQoL-SF™) questionnaire. This research aims to gather information concerning the quality of life among patients with hemodialysis due to chronic kidney failure at the dr. S. Hardjolukito Regional Military Hospital in Yogyakarta. The research employed a cross-sectional design. The respondents consisted of 65 patients selected through purposive sampling based on specific inclusion and exclusion criteria. The Independent T-test, Mann-Whitney test, Chi-Square test and Fischer test were conducted to define the association between quality of life and respondent characteristics. Most of the hemodialysis patients was male (50.8%) with average od age was 54.66 years old. The findings revealed that 64.6% of the respondents experienced moderate/poor quality of life, while 35.4% exhibited good quality of life. Statistical analysis established a significant relationship between respondent characteristics and quality of life based on the variables of age and duration of hemodialysis (p<0.05). Hemoglobin levels, number of prescribed medications, gender, education, occupation and income demonstrated no significant relationship with the quality of life. Among the respondents’ characteristics, age and duration of hemodialysis were associated with the quality of life.