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All Journal International Journal of Public Health Science (IJPHS) Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Urology Indonesian Journal of Cancer Chemoprevention Jurnal Farmasi Klinik Indonesia Mutiara Medika: Jurnal Kedokteran dan Kesehatan JURNAL PENGABDIAN KEPADA MASYARAKAT JOURNAL OF HEALTH SCIENCE (JURNAL ILMU KESEHATAN) AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat Window of Health : Jurnal Kesehatan Media Ilmu Kesehatan PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Care : Jurnal Ilmiah Ilmu Kesehatan Health Sciences and Pharmacy Journal Bhamada: Jurnal Ilmu dan Teknologi Kesehatan (E-Journal) Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Science Midwifery Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Avicenna : Journal of Health Research Asian Australasian Neuro and Health Science Journal (AANHS-J) Universitas Muhammadiyah Yogyakarta Undergraduate Conference Proceeding Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Prosiding Seminar Nasional Program Pengabdian Masyarakat Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan Berita Kedokteran Masyarakat Indonesian Health Journal Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Journal of Public Health and Pharmacy Jurnal Sains dan Kesehatan Bhamada: Jurnal Ilmu dan Teknologi Kesehatan (E-Journal) Jurnal Penelitian Keperawatan
Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati
2Departemen Epidemiologi, Kesehatan Masyarakat Dan Kedokteran Keluarga, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Muhammadiyah Yogyakarta.
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Journal : Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

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PENGARUH PEMBERIAN MINYAK BIJI JINTEN HITAM TERHADAP KADAR INTERLEUKIN-6 PADA PEROKOK AKTIF SEHAT Arif Santoso; Akrom Akrom; Laela Hayu Nuraini; Titiek Hidayati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (230.385 KB) | DOI: 10.36387/jiis.v7i1.861

Abstract

Exposure to cigarette smoke causes cellular oxidative stress and is the key to the inflammatory process in the lungs. Black cumin seed oil (MBJH) is one of the traditional medicines that is proven to contain the active substances timoquinone, nigelon and negelin which have antioxidant and immunomodulatory effects. Interleukin-6 (IL-6) is a proinflammatory cytokine and a multifunctional cytokine that is very important for determining the immune response, cell survival, apoptosis and proliferation and is a protumorogenic agent in many cancers. The purpose of this study was to determine the levels of IL-6 in healthy active smokers after being given MBJH at a dose of 0.5 ml/capsule. The research design used was a single blind Randomized Controlled Trial (RCT). A total of 39 healthy healthy active smokers were divided into 4 groups: Group 1 was given a placebo 3x1 capsules/day, group 2 was given MBJH 3x1 capsules/day, group 3 was given MBJH 3x2 capsules/day and group 4 was given MBJH 3x3 capsules/day. The placebo and MBJH interventions were administered for 30 days. Statistical analysis obtained showed that there was no significant difference in the mean levels of IL-6 between the treatment group and the placebo group with p>0.05. The results showed that the use of MBJH for 30 days can reduce the average level of Interleukin-6 but not significantly in healthy active smokers.
Co-Authors - nurkamila - nurkamila, - - Sagiran Ahmad Hamim Sadewa Akbar, Rizaluddin Akrom Akrom Akrom Akrom Akrom, Akrom Amal, Muhammad Ikhlasul Ardhitapramesti A.H.P. Arif Budi Setianto Arif Santoso Arif Santoso Arya Adiningrat Aryanto, Samsu Ayu Cahyaningtyas azizah khoiriyati Briliian Wahyudi, Rizqy Cahya Ningrum, Windy Astuti Dewi Puspita Dhara Indah Kartika Jati, Dhara Indah Kartika Diaz Habibah, Khalisha Eka Arikensiwi Eka Arikensiwi, Eka Emdat Suprayitno Emdat Suprayitno Endang Darmawan Erviana Erviana Erviana Erviana Fadil Abdillah Fahmy Abdul Haq Falasifah Ani Yuniarti, Falasifah Ani Faradisa Yuanita Fahmi Fathimah Kelrey Fuadi, Akhsanul Ginandjar Zukhruf Saputri Ginanjar Zuhruf Saputri Gumson Joshua Tampubolon Halimatusa'diyah, Thoharoh Handa Meru Erio Rakihara Haris, Tauranaswa Farrelabhista Putra Hastin Munifah T.F.F.S. Iffa Karina Permatasari Iffa Karina Permatasari Indrayanti, Indrayanti Indrayanti, Indrayanti Indri Nurasa Indri Nurasa Irna Susiati Kailani, Dzaka Ogan Amirudin Lutfi Khoiriyati, Azizah Kumala Syifa, Amira Kusumo, Mahendro Prasetyo Laela Hayu Nurani Laela Hayu Nurani Laili Apriani Lilis Suryani Lukman Hardia Marsetyawan HNE Soesatyo Nanik Sulistyani Naylil Mawadda Rohma Neni Probosiwi Nevi Seftaviani Nisa, Aida Novita Kurnisa Sari Nur Isnaini Nur Isnaini, Nur Nurcholid Umam Nurcholid Umam Kurniawan Nurisa Fikriyani L. Nurjanna Nurjanna Nurkhasanah Ogan Amirudin Lutfi, Dzaka Olyvia Wulan Kencana Panji Tutut Anggraeni Pradhana, Muhammad Ilham Satya Prasasti Bintarum Pratiwi, Adinda Aning Purwoko, Akhmad Edy Rachmayani, Tantri Rahmah Rahmah Ratna Indriawati Riska, Erlina Rizma Nurfadjrin Sagiran Sagiran Shabrina Arwi Laily Shiko Indrawan Siti Pandanwangi TW Sri Hesthi Sonyo Sri Sumaryani Subroto, Bramastha Alfanda Sumaryani, Sri Sun, Suny Suprayitno, Emdat Tantri Rachmayani Theodola Baning Rahayujati Thoharoh Halimatusa'diyah Thoharoh Halimatusa’diyah Thosimomia Tamimi, Nia Tri Pitara Mahanggoro Tsai, Mei Ling Vivi Sofia Yuningtyaswari Yuningtyaswari Yuningtyaswari Yuningtyaswari Zuniarto, Ahmad Azrul