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Karakteristik Pasien Pneumotoraks Et Causa Penyakit Paru Obstruktif Kronik (PPOK) di Bangsal Paru RSUP Dr. M. Djamil Padang Angela, Sonnya Morisa; Sabri, Yessy Susanty; Hanum, Fathiya Juwita; Rasyid, Rosfita; Russilawati, Russilawati; Nofendra, Ade
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 3 (2024): September 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i3.986

Abstrak Latar Belakang: Pneumotoraks merupakan kelainan pada paru yang ditandai dengan terdapatnya udara pada rongga pleura. Terdapat beberapa jenis pneumotoraks salah satunya Pneumotoraks Spontan Sekunder (PSS). Pneumotoraks Spontan Sekunder (PSS) terjadi ketika penyakit dasar dengan target organ paru pada seseorang semakin memburuk. Penyakit paru tertinggi pada kasus PSS adalah Penyakit Paru Obstruktif Kronik (PPOK). Objektif: Mengetahui karakteristik pasien penderita pneumotoraks spontan sekunder yang disebabkan PPOK di Bangsal Paru RSUP Dr. M. Djamil Padang pada periode 2018 – 2021 berdasarkan usia, jenis kelamin, status merokok, keluhan utama, komorbid, dan sisi pneumotoraks pasien. Metode: Penelitian ini merupakan penelitian deskriptif retrospektif menggunakan rekam medis pasien pneumotoraks spontan yang disebabkan PPOK. Pengambilan sampel penelitian menggunakan teknik penelitian sensus sesuai kriteria inklusi. Hasil: Terdapat 26 pasien yang memenuhi kriteria inklusi dalam penelitian ini. Terdapat 50% pasien berada pada kelompok usia 55-64 tahun, 96,15% pasien berjenis kelamin laki-laki, 55,85% sebagai bekas perokok, 100% pasien dengan keluhan utama dispnea, komorbid pneumonia komuniti 34,09%, dan 53,85% pasien pneumotoraks sisi kiri. Kesimpulan: Kebanyakan pasien adalah kelompok usia 55-64 tahun, jenis kelamin laki-laki, merupakan bekas perokok, keluhan utama dispnea, komorbid pneumonia komuniti, dan mengenai sisi kiri dada. Kata kunci: karakteristik, penyakit paru obstruktif kronik, pneumotoraks spontan

Gambaran Klinis COVID-19 pada Mahasiswa FK Universitas Andalas Berdasarkan Status Vaksinasi COVID-19 Hanif, Rayhendra; Suharti, Netti; Rasyid, Rosfita; Putra, Andani Eka; Russilawati, Russilawati; Izzah, Amirah Zatil
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 4 (2024): Desember 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i4.1256

Background: COVID-19 is a disease caused by SARS-CoV-2 that’s highly infectious and has caused a pandemic. Vaccines are one of the most effective measures to control the spread of COVID-19. COVID-19 vaccines work by targeting the viral spike protein which can be varied in each variant of SARS-CoV-2 that threatens vaccines’ performance. This may allow breakthrough infection to occur with varying clinical characteristics. Objectives: This study aims to determine the clinical characteristics of COVID-19 on students at Medical Faculty of Andalas University based on their COVID-19 Vaccination status Methods: This research was observational descriptive. Data were collected using questionnaire with total sampling technique from December 2022 to January 2023 at the Medical Faculty of Andalas University. The questionnaire contained identity of respondent’s history, clinical characteristics of COVID-19 and their COVID-19 vaccination status. Questionnaire data were processed and displayed in frequency distribution tables. Results: The result showed that 100 samples out of 241 populations on this study were mostly women, mean age of 21.2 years old ± 0,7, range of age between 19-23 years old, most were already vaccinated for the third time, most were infected only once, and most infections happened after the second vaccination. The most common symptoms were fever, sore throat and cough. The severity of COVID-19 infections were relatively mild based despite of the vaccination status. No samples were reported of having severe critical illness. Conclusion: The symptoms of COVID-19 were relatively similar regardless of the vaccination status and the severity of COVID-19 infections were relatively mild regardless of the vaccination status on students at Medical Faculty of Andalas University.

Do Ventilator Bundles Reduce Ventilator-Associated Pneumonia? A Meta-Analysis of Randomized Controlled Trials Reski Anugrah Zuandra; Irvan Medison; Russilawati
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 3 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i3.1233

Background: Ventilator-associated pneumonia (VAP) is a serious complication in mechanically ventilated patients, leading to increased morbidity, mortality, and healthcare costs. Ventilator bundles are evidence-based practices aimed at preventing VAP. This meta-analysis evaluated the effectiveness of ventilator bundles in reducing VAP incidence in critically ill adults. Methods: A systematic search of PubMed, Embase, and Cochrane Central Register of Controlled Trials was conducted from January 2013 to December 2024. Randomized controlled trials (RCTs) comparing ventilator bundles to standard care in adult patients receiving mechanical ventilation were included. The primary outcome was the incidence of VAP. Secondary outcomes included mortality, length of intensive care unit (ICU) stay, and duration of mechanical ventilation. Pooled risk ratios (RR) with 95% confidence intervals (CI) were calculated using a random-effects model. Results: Nine RCTs involving 2,850 patients met the inclusion criteria. The implementation of ventilator bundles was associated with a significant reduction in VAP incidence (RR 0.68, 95% CI 0.55-0.84, p=0.0002). Mortality (RR 0.89, 95% CI 0.75-1.05, p=0.16) and duration of mechanical ventilation (mean difference -1.2 days, 95% CI -2.8 to 0.4, p=0.13) did not significantly differ between groups. However, a significant reduction in ICU length of stay was observed in the ventilator bundle group (mean difference -2.1 days, 95% CI -3.5 to -0.7, p=0.004). Conclusion: This meta-analysis demonstrates that ventilator bundles are effective in reducing VAP incidence in critically ill adults. While no significant impact on mortality was observed, ventilator bundles were associated with a shorter ICU length of stay. These findings reinforce the importance of implementing ventilator bundles as a standard of care in ICUs to improve patient outcomes.

Managing Catamenial Pneumothorax: Challenges of Diagnosis and Therapy, Literature Review Pratama, Fadel Ahmad; Russilawati, Russilawati; Herman, Deddy
Jurnal Impresi Indonesia Vol. 4 No. 5 (2025): Indonesian Impression Journal (JII)
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v4i5.6522

Catamenial pneumothorax (CP) is a rare and recurrent spontaneous pneumothorax in women, typically occurring from 24 hours before menstruation to 72 hours afterward. While once considered uncommon, CP is now recognized in up to 30% of pneumothorax cases among women. This study aims to provide a comprehensive literature-based analysis of the etiology, diagnosis, and multidisciplinary management of CP. The research method used is a literature review that analyzes clinical cases, diagnostic imaging, histopathological findings, and treatment outcomes from various databases and published case reports. Findings suggest that while the etiology remains multifactorial—including diaphragmatic defects, lymphovascular dissemination, and hormonal influences—the use of video-assisted thoracic surgery (VATS) combined with pleurodesis and postoperative hormonal therapy (e.g., GnRH analogs) significantly reduces recurrence rates, down to 0% in some combined therapy cases. Imaging modalities like MRI during menstruation increase diagnostic accuracy. The study also underscores the importance of surgical timing, hormonal therapy continuity, and long-term monitoring for recurrence prevention. Implications of this study include the need for standardized treatment protocols and the incorporation of gynecological and thoracic collaboration in managing CP. Future research should explore biomarkers and prospective multicenter trials to refine diagnostic and therapeutic strategies.

Challenging the Paradigm: A Clinicopathological Case Series on the Discordance between Cutaneous Burn Severity and Airway Injury Following a Volcanic Pyroclastic Flow Exposure Adrifen Berti Akbar; Oea Khairsyaf; Russilawati Russilawati; Dimas Bayu Firdaus
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 11 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i11.1439

Background: Inhalation injury accompanying severe burns is a major driver of morbidity and mortality. The pathophysiology of injury from volcanic eruptions—a unique combination of extreme heat, abrasive particulates, and corrosive gases—is distinct from typical combustion smoke and not well-characterized. Flexible bronchoscopy is the gold standard for diagnosing and grading airway injury, yet its application in this context, particularly in relation to external burn severity, is unclear. Case presentation: We present a retrospective analysis of two climbers who were the sole survivors admitted to our tertiary center after exposure to the pyroclastic flow from the 2023 Mount Marapi eruption. A 19-year-old female with 40% Total Body Surface Area (TBSA) deep burns and a 20-year-old male with 30% TBSA deep burns both presented with signs concerning for inhalation injury. Despite the devastating extent of their cutaneous injuries, flexible bronchoscopy in both patients revealed only mild, Grade 1 endobronchial injury (mucosal erythema and edema) based on the Abbreviated Injury Score (AIS) classification. The first patient succumbed to septic shock from her burns, while the second patient showed significant respiratory improvement following therapeutic bronchial lavage and made a full recovery. Conclusion: This case series presents hypothesis-generating evidence suggesting that in victims of open-air volcanic pyroclastic flows, the severity of cutaneous burns may be a poor predictor of the degree of underlying endobronchial damage. These findings underscore the potential necessity of a low threshold for early flexible bronchoscopy to accurately diagnose, stratify, and therapeutically intervene in this unique patient population, irrespective of TBSA.

Challenging the Paradigm: A Clinicopathological Case Series on the Discordance between Cutaneous Burn Severity and Airway Injury Following a Volcanic Pyroclastic Flow Exposure Adrifen Berti Akbar; Oea Khairsyaf; Russilawati Russilawati; Dimas Bayu Firdaus
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 11 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i11.1439

Background: Inhalation injury accompanying severe burns is a major driver of morbidity and mortality. The pathophysiology of injury from volcanic eruptions—a unique combination of extreme heat, abrasive particulates, and corrosive gases—is distinct from typical combustion smoke and not well-characterized. Flexible bronchoscopy is the gold standard for diagnosing and grading airway injury, yet its application in this context, particularly in relation to external burn severity, is unclear. Case presentation: We present a retrospective analysis of two climbers who were the sole survivors admitted to our tertiary center after exposure to the pyroclastic flow from the 2023 Mount Marapi eruption. A 19-year-old female with 40% Total Body Surface Area (TBSA) deep burns and a 20-year-old male with 30% TBSA deep burns both presented with signs concerning for inhalation injury. Despite the devastating extent of their cutaneous injuries, flexible bronchoscopy in both patients revealed only mild, Grade 1 endobronchial injury (mucosal erythema and edema) based on the Abbreviated Injury Score (AIS) classification. The first patient succumbed to septic shock from her burns, while the second patient showed significant respiratory improvement following therapeutic bronchial lavage and made a full recovery. Conclusion: This case series presents hypothesis-generating evidence suggesting that in victims of open-air volcanic pyroclastic flows, the severity of cutaneous burns may be a poor predictor of the degree of underlying endobronchial damage. These findings underscore the potential necessity of a low threshold for early flexible bronchoscopy to accurately diagnose, stratify, and therapeutically intervene in this unique patient population, irrespective of TBSA.

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