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All Journal Bulletin of Chemical Reaction Engineering & Catalysis The Journal of Pure and Applied Chemistry Research Jurnal Riset Kimia IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Science and Technology Indonesia Chimica et Natura Acta ALCHEMY Jurnal Penelitian Kimia Indonesian Journal of Chemistry BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains Surya Abdimas Molekul: Jurnal Ilmiah Kimia Jurnal Ilmu Kefarmasian Indonesia Jurnal Pengabdian Al-Ikhlas Bioscientist : Jurnal Ilmiah Biologi Jurnal Kimia dan Kemasan Jurnal Riset Fisika Indonesia Molekul: Jurnal Ilmiah Kimia Bulletin of Chemical Reaction Engineering & Catalysis Bencoolen Journal of Pharmacy Rafflesia Journal of Natural and Applied Sciences (RJNAS)
SALPRIMA YUDHA S
Department Of Chemistry, Faculty Of Mathematics And Natural Sciences, Universitas Bengkulu, Bengkulu, 38122, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Aktivitas Antibakteri Secara In-Vitro Ekstrak Metanol Excoecaria cochinchinensis Lour dan Kombinasinya dengan Obat Komersial Nurhasana, Devi; Febriansyah, Rahmaga; Avidlyandi, Avidlyandi; S., Salprima Yudha; Banon, Charles; Oktiarni, Dwita; Adfa, Morina
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1383

Abstract

The purpose of this study was to look into the antibacterial activity of methanolic extract of Excoecaria cochinchinensis as well as the effect of its combination with antibiotics on the growth of Klebsiella pneumoniae, Enterobacter aerogenes, and Staphylococcus epidermidis. The antibacterial activity test was carried out using the well diffusion method, and the combined effect of the extract and antibiotics was observed using the paper strip diffusion method. At various concentrations (25, 50, 75, 100, 150, 200, and 250 mg/mL), the extract significantly inhibited the growth of K. pneumoniae, E. aerogenes, and S. epidermidis. The inhibitory zone's diameter increased proportionally with the extract concentration. The growth of K. pneumoniae and S. epidermidis was then classified as extremely sensitive (+++) to the addition of the extract at 200 and 250 mg/mL concentrations, meanwhile, E. aerogenes’s with 250 mg/mL of the extract. Secondary metabolites such as oleanolic acid, arjunolic acid, scopoletin, kaempferol, quercetin, diterpenoid compounds, tannins, and other phenolics have been reported from E. cochinchinensis leaves and are thought to be responsible for its antimicrobial activity. The effect of the extract’s combination with antibiotics was insignificant compared to their individual activity, thereby classifying them as indifferent.
Aktivitas Antibakteri Ekstrak Daun Mangrove (Rhizophora mucronata) pada Bakteri Helicobacter pylori Penyebab Tukak Lambung Pertiwi, Reza; S, Salprima Yudha; Wibowo, Risky Hadi; Notriawan, Doni; Nasution, Riski Padilah; Azhar, Afra Wafiqah
Bioscientist : Jurnal Ilmiah Biologi Vol. 12 No. 1 (2024): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v12i1.9957

Abstract

Mangrove (Rhizophora mucronata) is a plant that can be used as an antibacterial because it contains several secondary metabolite compounds such as saponins and flavonoids which can inhibit bacterial growth. This research aims to determinehe antibacterial activity of mangrove leaves (Rhizophora mucronata) in inhibiting the growth of Helicobacter pylori bacteria. This research is an in vitro study using the agar dilution method for 2-5 days. The treatment groups consisted of negative, positive (co-trimoxazole), ethanol extract of mangrove leaves (Rhizophora mucronata) with concentrations of6.25%, 12.5%, 25% and 50%. The treatment was carried out by adding the Helicobacter pylori suspension to a petri dish containing agar media. Observations were made to see whether bacteria grew in the media. The data is then analyzed and broken down from the results of calculating the diameter of the inhibition zone. The test results showed that the ethanol extract of mangrove leaves (Rhizophora mucronata) had antibacterial activity in the weak category in inhibiting the growth of Helicobacter pylori bacteria. This antibacterial activity can be caused because mangrove leaves (Rhizophora mucronata) contain secondary metabolite compounds with an antibacterial mechanism of action, so this is in line with the results of this study.
Analisis Bibliometrik Penelitian Bio-Sintesis Nanopartikel Perak (NP-Ag) di Indonesia Zuas, Oman; Nazarudin, Nazarudin; Yudha, Salprima; Yaumidin, Umi K; Yuwono, Suripto D; Aritonang, Anthoni B
Jurnal Riset Fisika Indonesia Vol 1 No 2 (2021): Juni 2021
Publisher : Jurusan Fisika, Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jrfi.v1i2.2380

Abstract

Tulisan ini menyajikan analisis bibliometrik terhadap artikel ilmiah yang terbit dalam kurun waktu 2011-2020 terkait penelitian bio-sintesis nanopartikel perak (NP-Ag) di Indonesia. Analisi bibliometric dilakukan terhadap 55 artikel ilmiah yang diperoleh melalui pencarian di database Scopus. Hasil analisis menunjukkan bahwa penelitian dan pengembangan bio-sintesis NP-Ag di Indonesia cukup mendapat banyak perhatian yang dibuktikan oleh adanya temuan berikut. Trend pertumbuhan artikel ilmiah terkait NP-Ag diperkirakan masih akan terus mengalami kenaikan untuk beberapa tahun ke depan. Posisi pertama untuk peneliti dan institusi yang paling produktif dalam memublikasikan artikel ilmiah adalah masing-masing ditempati oleh Handayani, W., dan Universitas Indonesia (UI). Handayani, W. juga diketahui merupakan peneliti yang mempunyai jaringan kolaborasi yang terbanyak, dan untuk kolaborasi tingkat insitusi, di tempati oleh Institut Teknologi Sepuluh November (ITS). Untuk jurnal sebagai sumber artikel ilmiah yang paling menonjol ditempati oleh “Biointerface Research in Applied Chemistry”. Lebih lanjut, hasil analisis konten terhadap 55 jurnal ilmiah yang terbagi menjadi tiga klaster menunjukkan bahwa penelitian bio-sintesis dimasa yang akan datang hendaknya melibatkan peneliti dari multidisiplin ilmu dengan hasil yang lebih inovatif, dengan arah dan skala pengembangan NP-Ag yang bersifat aplikatif, serta menuju arah industrilisasi.
Co-Authors Afra Wafiqah Azhar Agus Martono H. Putranto Alvin Reagen, Muhamad Anisa Ulya Darajat Annisa Ramadhani Aritonang, Anthoni Batahan Arman, Etriyanto Asdim Asdim Askhan, Jimmy Aswin Falahudin Aswin Falahudin Aswin Falahudin Aswin Falahudin Aswin Falahudin Aswin Falahudin Aswin Falahudin Avidlyandi, Avidlyandi Azhar, Afra Wafiqah Bambang Trihadi Buistu Arba’a Nuyuh Putri Charles Banon Demi Dama Yanti Dennie Oktrin Wicaksono Doni Notriawan Dwita Oktiarni Efendi, Pahran Eka Angasa Eka Angasa Falahudin, Aswin Fatan Umbara Febriansyah, Rahmaga Herlina Herlina Herlina Herlina I Putu Mahendra Ika Diana Evita Insin, Numpon Irfan Gustian Irfan Gustian Irfan Gustian Irfan Gustian John Hendri Kazi, Mohsin Khafit Wiradimafan Liana Wahyuni Liesaiani Daefisal, Octakireina M. Rafi Mardlia, Zulfikri Achid Mifta Violina Aniza Morina Adfa Morina Adfa Muhamad Alvin Reagen Munifilia Ekasari Nasution, Riski Padilah Nazarudin Nazarudin Nazarudin Nesbah Nesbah Nesbah, Nesbah Noor Haida Mohd Kaus Notriawan, Doni Nurhasana, Devi Octakireina Liesaini Daefisal Oman Zuas Oman Zuas Perdani, Meka Saima Putri, Yona Rais Akbar Syahputra Reagen, Muhamad Alvin Reza Pertiwi Reza Pertiwi Reza Pertiwi Riski Padilah Nasution Risky Hadi Wibowo Risky Hadi Wibowo Saiqa Ikram Saiqa Ikram Setyo Eko Nugroho Nugroho Sirikanjana Thongmee Sri Ningsih Suli Anggria Murni Supriati, Rochmah Suripto D Yuwono Swadexi Istiqphara Swadexi Istiqphara Swadexi Istiqphara Swadexi Istiqphara, Swadexi Syalfinaf Manaf Teja Dwi Sutanto Triawan, Deni Agus Umi K Yaumidin Wibowo, Risky Hadi Wuri Prameswari Yaumidin, Umi K Yuwono, Suripto D