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All Journal Jurnal Ilmu Dasar Jurnal Sains Dasar Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat PROSIDING SEMINAR KIMIA KOVALEN: Jurnal Riset Kimia Jurnal Kimia Mulawarman Science and Technology Indonesia JURNAL ATOMIK Jurnal Sustainable: Jurnal Hasil Penelitian dan Industri Terapan Bisma: Jurnal Bisnis dan Manajemen Spektrum Analisis Kebijakan Pendidikan VALUE: Journal of Business Studies
Chairul Saleh
Jurusan Kimia Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Mulawarman
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Environmental Science Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Physics Social Sciences Other

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UJI TOKSISITAS DAN PENENTUAN AKTIVITAS ANTIOKSIDAN DENGAN METODE DPPH DARI METABOLIT SEKUNDER FRAKSI n-HEKSAN, ETIL ASETAT DAN METANOL-AIR DAUN SISIK NAGA (Drymoglossum piloselloides [Linn.] Pr.) Erwin -; Dwi Fitria Sari; Chairul Saleh
PROSIDING SEMINAR KIMIA SEMINAR NASIONAL KIMIA 2013
Publisher : PROSIDING SEMINAR KIMIA

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Abstract

Phytochemical, toxicity test had been done that used Brine shrimp (Brine shrimp lethality test) and antioxidant activity test using methanol extract from sisik naga leaf (Drymoglossum piloselloides (Linn). Pr) fraction that taken from Kutai Kartanegara, East Kalimantan. Sisik naga leaf was extracted by methanol and then concentrated using rotary evaporator. Then that crude extract was fractioned by n-hexane, ethyl acetate and methanol-water. Based on phytochemical test of the sisik naga leaf show that crude methanol extract, n-hexane fraction and ethyl acetate fraction was contain alkaloid, flavonoid and steroid at methanol-water fraction was contain alkaloid and phenol. Brine shrimp lethality test show that lethality level of Artemia Salina (L) that used Probit SAS Analyze to determine value of Lethal Concentration 50% (LC 50 ). The test showed that the most active was crude n-Hexane extract with LC 50 value of 0,0910 ppm. Antioxidant activity test of extracts from crudge methanol and some variations fractioned using DPPH radical reduction (2,2 '-diphenyl-1-picrylhydrazil) using Spectrophotometer. The test showed that the most active and recommended to used as antioxidant is methanol-water fraction with IC 50 values is at 74.51 ppm and LC 50 values is at 87749.9219 ppm.
ANTIHYPERGLYCEMIC TEST OF ETHANOL EXSTRACT OF DURIAN (Durio zibethinus Murr.) PEEL AGAINTS MALE MICE (Mus Musculus) Hamsiana -; Rudi Kartika; Chairul Saleh
PROSIDING SEMINAR KIMIA PROCEEDING OF INTERNATIONAL CONFERENCE 2015
Publisher : PROSIDING SEMINAR KIMIA

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Diabetes mellitus (DM) is a metabolic disorder and characterized by hyperglycemic circumstances. Hyperglycemic is a condition where the glucose levels ini the blood increased dramatically. One of the pharmacological therapy ia to use ofdrugs that can reduse glucose levels in the blood. Phytochemical test and antihyperglicemic activity from durian (Durio zibethunus Murr.) peel have been carried out. Durio zibethinus Murr. peel was macerated with ethanol 96% then concentrated with rotary evaporators. It obtained rendemen 13.33% . Based on the test result of phytochemistry of secondary metabolites compounds from durian peel showed that etahanol extract containing flavonoid, alkaloid, fenolik, triterpenoid and saponin. Antihyperglicemic activity test use animal test male mice that is injected aloksan. Measurement of blood sugar levels using glucometer and glucose test strip. From antihyperglicemic test it showed that the effectiveness of blood sugar level doses of 36 mg/kg BW from the
Skrining Fitokimia, Uji Toksisitas dan Uji Peredaman Radikal DPPH Ekstrak Daun Gelinggang (Cassia alata L): Phytochemical Screening, Toxicity Test and DPPH Radical Scavenging Test of Cassia alata L (Gelinggang) Leaves Extract Izkia Mawaddah; Erwin E; Chairul Saleh
KOVALEN: Jurnal Riset Kimia Vol. 6 No. 1 (2020): Edisi April
Publisher : Chemistry Department, Mathematics and Natural Science Faculty, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/kovalen.2020.v6.i1.15045

Abstract

Cassia alata L. (Gelinggang) one of the plants known as medicinal plants, especially for the treatment of skin diseases. The purpose of this study was to determine the type of secondary metabolites using phytochemical tests, toxicity with the BSLT method and antioxidant properties against DPPH radicals from the extract of the Gelinggang leaves. The results of the study showed extracts of Gelinggang leaves containing alkaloids, triterpenoids, steroids, and quinones. Based on the results of toxicity and antioxidant tests showed that Gelinggang leaves extract was very toxic to Artemia salina shrimp and it was a strong antioxidant against DPPH radicals with LC50 and IC50 were 28.84 ppm and 73.57 ppm, respectively. Keywords: Gelinggang, Cassia alata L., toxicity, antioxidants, DPPH
ANALISIS KAFEIN DALAM KOPI ROBUSTA (TORAJA) DAN KOPI ARABIKA (JAWA) DENGAN VARIASI SIKLUS PADA SOKLETASI Tria Annisa Rizky; Chairul Saleh; Alimuddin -
JURNAL KIMIA MULAWARMAN Vol 13 No 1 (2015)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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The research about analysis of caffeine content on coffee Robusta (Toraja) and coffee Arabika (Jawa) with cycle variations using spectrophotometer UV has been done. Coffee extract obtained throughsoxhletation with ethanol 96 % and variation cycles used is 3, 6, 9, 12 and 15, tested with spectrophotometer UV at a wavelength of 272 nm. The result of this research was obtained the caffeine content in coffee Robusta (Toraja) for 3, 6, 9, 12, 15 cycles consecutive is 1.439 mg/L, 2.158 mg/L, 2.695 mg/L, 2.887 mg/L and 3.700 mg/L. The caffeine content obtained coffee Arabika (Jawa) for 3, 6, 9, 12, 15 cycles consecutive is 0.474 mg/L, 0.478 mg/L, 1.056 mg/L, 1.540 mg/L and 1.926 mg/L respectively.Keywords: Coffee Robusta, Coffee Arabika, Ethanol 96 %, Soxhletation, Caffeine, Spectrophotometer UV
ANALISIS TOTAL SULFUR TERHADAP SAMPEL FEED GAS DENGAN MEMBANDINGKAN STANDAR GAS DAN STANDAR LIQUID MENGGUNAKAN METODE TS-100V Eko Haryanto; Rahmat Gunawan; Chairul Saleh
JURNAL KIMIA MULAWARMAN Vol 12 No 1 (2014)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

The total sulfur analysis in the feed gas sample by using standard gas and liquid has been researched. The concentration of total sulfur obtained from a calibration curve by using standard gas or liquid by TS - 100V. Based on the analysis of measurement linearity, by making curve a linearity from a standard gas H 2 S was 0.999 and standard liquid dibutyl sulfide was 0.998, where both the standard curve can be as a calibration curve because each the value of the correlation coefficient (r) having worth >0.995. Based on the analysis of measurement precision namely repeatability by measuring a feed gas sample train G as many as 5 times been gained. RSD value was 4.17 in standard gas and 4.70 in standard liquid. Both the calibration curve has been accepted because the relative standard deviation values less than 0.67 from Horwitz and still into get allowed range values from 7.3 to 11%. Based on the analysis of accuracy’s measurement is percent recovery for the standard gas was 100.578% and for standard liquid was 104.380%. Both of them has been accepted because it still fit in the allowed range values 80-110%.Keywords : Total Sulfur, H 2 S Standard Gas, Standard Liquid Dibutyl Sulphites and TS-100V
UJI FITOKIMIA, TOKSISITAS DAN AKTIVITAS ANTIBAKTERI EKSTRAK BERBAGAI FRAKSI DAUN MARA (Macaranga tanarius (L.) M.A) TERHADAP BAKTERI Staphylococcus aureus dan Escherichia coli Ana Arum Sari; Chairul Saleh; Erwin -
JURNAL KIMIA MULAWARMAN Vol 12 No 2 (2015)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Phytochemical, toxicity and antibacterial activity tests of total extract, fractions of n-heksana, ethyl acetate and ethanol-water from mara leaf (Macaranga tanarius (L.) M.A) from Samboja, East Kalimantan has been carried out. Based on the secondary metabolites phytochemical test of the (Macaranga tanarius (L.) M.A) leaf show that total extract is contain alkaloid, flavonoid, phenolic and steroid. n-hexane fraction is contain alkaloid, flavonoid and steroid. Ethyl acetate fraction is contain phenolic and triterpenoid. Ethanol-water fraction is contain alkaloid and phenolic. Brine shrimp lethality test values obtained Lethal Concentration 50 % (LC50) total extract 23.99 ppm , n-heksana fraction 13,93 ppm, ethyl acetate fraction 468,25 ppm and ethanol-water fraction 283,67 ppm. Antibacteria activity test of extracts for Staphylococcus aureus bacteria (positive Gram) and Escherichia coli (negative Gram) was carried out by paper disc method. The test showed that the most active were ethyl acetate fraction with minimum inhibitor consentration of 0,125- 0,5 % (b/v) which clear zone diameter was 7,25 mm on Staphylococcus aureus bacteria and 6,25 mm on Escherichia coli bacteria.
Uji Fitokimia, Toksisitas dan Aktivitas Antioksidan Fraksi n-heksan dan Etil Asetat terhadap Ekstrak Jahe Merah (Zingiber officinale var. amarum) Alpina Nora Kaban; Daniel Tarigan; Chairul Saleh
JURNAL KIMIA MULAWARMAN Vol 14 No 1 (2016)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Has conducted research on the phytochemical test, toxicity test and test the antioxidant activity of the fraction of n-hexane and ethyl acetate to extract red ginger (Zingiber officinale amarum var.). The dried leaves weighing 382 grams, was macerated using methanol, filtered and concentrated by rotary evaporator. Then the total extract of red ginger in fractionation with n-hexane and ethyl acetate. Based on the test results of secondary metabolites phytochemical extracts of total red ginger (Zingiber officinale var amarum.) Are alkaloids, flavonoids, triterpenoids and phenolic. N-hexane fraction contains alkaloids, flavonoids, steroids, triterpenoids and phenolic. Ethyl acetate fractions contain alkaloids, flavonoids, triterpenoids and phenolic. Toxicity test showed the mortality rate of shrimp larvae Artemia salina Leach using Probit Analysis SAS (Statistical Analysis System) to determine the value of 50% Lethal Concentration (LC50), showed that the fraction of n-hexane toxicity with LC50 values of 63.8130 ppm; extracts of total was 71.0121 ppm and ethyl acetate was 3821.89 ppm. Test the antioxidant activity using DPPH free radical reduction in the spectrophotometer and IC50 values obtained on a total extract was 32.19 ppm; n-hexane was fraction 35.63 ppm; and ethyl acetate fraction was 25.69 ppm.
ANALISIS KADAR ION BESI (Fe2+) DAN ION TIMBAL (Pb2+) DALAM IKAN MAKAREL KEMASAN KALENG BERDASARKAN LAMA WAKTU PENYIMPANAN Dessy Karlina; Alimuddin Alimuddin; Chairul Saleh
JURNAL KIMIA MULAWARMAN Vol 16 No 2 (2019)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v16i2.450

Abstract

Analysis of iron ion (Fe2+) and lead ion (Pb2+) content in canned mackerel based long storage time has been investigated. The content of iron ion (Fe2+) and lead ion (Pb2+) has been analysed used the instrument Atomic Absorption Spectrophotometer (AAS). Based on long storage time result analysis of the content of iron ion (Fe2+) in canned mackerel the lowest is 2,71 mg/Kg with long storage time of 33 month and the highest is 5,21 mg/Kg with long storage time of 9 month while the result analysis of lead ion (Pb2+) in canned mackerel is not detected. Based on the result conclude is long storage time not affect the levels iron ion (Fe2+) and lead ion (Pb2+) in canned mackerel.
UJI TOKSISITAS (Brine Shrimp Lethality Test) dan UJI AKTIVITAS ANTIBAKTERI DAUN KEMBANG BULAN (Tithonia diversifolia A. Gray) TERHADAP BAKTERI Staphylococcus aureus dan Escherichia coli Mira Wahyuni; Chairul Saleh; Rudi Kartika
JURNAL KIMIA MULAWARMAN Vol 12 No 2 (2015)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Phytochemical, toxicity tests (Brine Shrimp Lethality Test) and the antibacterial activity of kembang bulan leaf (Tithonia diversifolia A. Gray). Phytochemical test results of secondary metabolites kembang bulan leaf (Tithonia diversifolia A. Gray) show that the ethanol extract contains alkaloids, flavonoids, steroids, phenolic and saponins. N-hexane fraction containing alkaloids and steroids. Ethyl acetate fraction contain flavonoids and steroids. Shrimp larvae toxicity test values obtained Lethal Concentration 50% (LC 50 ) at 383.5660 ppm ethanol extract, fractions 325.1583 ppm n-hexane and ethyl acetate fraction 196.3755 ppm. Test antibacterial activity against Staphylococcus aureus (Gram positive) and Escherichia coli (Gram negative) indicates that the most active fraction was ethanol extract the value of minimum inhibitory 1-2% (w / v) where the clear zone diameter of 8.5 to 9, 75 mm in the bacterium Escherichia coli and from 7.5 to 9.75 mm in Staphylococcus aureus. 
Aktivitas Antioksidan dan Antimalaria Senyawa Fenolik dari Daun Macaranga beccariana Merr. Eva Marliana; Chairul Saleh; Medi Hendra
JURNAL KIMIA MULAWARMAN Vol 15 No 2 (2018)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v15i2.611

Abstract

Macaranga beccariana Merr. is an endemic plant of Kalimantan which is no report yet about its biological activity and isolated compounds. Therefore, in order to know the potency of M. beccariana, determination of antioxidant and antimalarial activities along with isolation of bioactive compounds from this plant must be carried out. In this research, the leaves of M. beccariana was extracted using methanol to obtain methanol extract. Furthermore, the extract was separated and purified to obtain compound 1 and compound 2. Based on structure elucidation using spectrometer analysis including UV, 1H and 13C NMR, compounds 1 and 2 which belong to phenolics were identified as 4-hidroxybenzoic acid and 3,4-dihidroxybenzoic acid, respectively. Moreover, antioxidant activity using DPPH (2,2-diphenyl-1-picrylhydrazyl) and antimalarial activity towards Plasmodium falciparum strain 3D7 using Giemsa staining were performed. Rutine and chloroquine difosfat were used as positive controls for antioxidant and antimalarial, respectively. The results showed that the methanol extract of M. beccariana and its isolated compounds (1 and 2) are active for those activities. It can be concluded that the leaves of M. beccariana has good potency as antioxidant and antimalarial agents.
Co-Authors Agung Prasetyo Ajeng Kartini Akbar, Fath Ali Alimuddin - Alimuddin - Alimuddin Alimuddin Alpina Nora Kaban Ami, Suyatmi Ana Arum Sari Ana Arum Sari, Ana Arum Ardiansyah - Ardiansyah - Arifah, Churniati Nur Arwidhiah, Nanda Ary Rizki Darmawi Ary Rizki Darmawi, Ary Rizki Aulia Husna Rabbani Azhar Seli Apriani Azhar Seli Apriani, Azhar Seli Barikah, Kuni Z. Bastara, Dimas B. Bohari Yusuf Bonita Tahir Daniel Daniel - Daniel - Daniel -, Daniel Daniel Daniel Daniel Daniel Daniel Daniel Daniel Tarigan Deni Karisnawati Dessy Karlina Desy Ridho Rahayu Dewi, Camelia Eugenia Djihan Ryn Pratiwi, Djihan Ryn Dwi Fitria Sari Dwi Perwitasari Wiryaningtyas, Dwi Perwitasari Eci Endang Sinulingga Eko Haryanto Eko Haryanto Elean, Samuel Ema Desia Prajitiasari Erwin - Erwin - Erwin E Erwin Erwin Erwin Erwin Erwin Erwin Eva Marliana, Eva Fadillah, Fahmi Farhany, Farhany Farida Amir Farida Amir, Farida Fauziah, Nadiya Ayu Hairani, Rita Hammamiyah, Ulinnuha Hamsiana - Hevin Muttaqin Husnul Chatimah Indra Masmur Izkia Mawaddah Jaya, Edi Novian Juwita, Retno Karolina Sinukaban KHOIRUN NISAK Kusumaningrum, Indah Yulia Kusumawardani, Niken Lembang, Darmita Tiku Lutfiana Devi Kurnia M.Riza Agus Pramana Magdaleni Agustina Rahayu Magdaleni, Agustina R. Magdaleni, Agustina Rahayu Marsella, Virna Rindra Masmur, Hestina Medi Hendra, Medi Mira Wahyuni Mira Wahyuni, Mira Muhammad Rivai Mujahidin1, Muhamad Mustafidah - Mustafidah -, Mustafidah Mutma Inna Nadhirah - Natalia, Princessa Noor Hindryawati, Noor Nugraheni, Dyah Ayu Nur Aina Nur Aini Haryati Nuranda, Apri Nyoman Gede Krishnabudi Oman, Aries Panannangan, Josua K. Pangaribuan, Fransiscus X. Rico Pindan, Neli Peni Prabowo, Rachmat Udhi Pratiwi, Ricka Indria Precelia, Sari Clara Priyanto, Fajar Wahyu Purnamie Titisari Purwanti, Gettik Andri Puspita, Leonita Dwi Puspitasari, Intan Dessy Rachman, Ferry Aditya RAHMAT GUNAWAN Rahmat Gunawan Ramadhan, Aulia Ravensca, Irene Rindawati, Novi Ritbey Ruga Ritson Purba, Ritson Rochman, Mayasari Azhari Rohmat Hidayat Rohmat Hidayat Rudi Kartika, Rudi Ruga, Ritbey Ryn Pratiwi, Djihan Saibun Sitorus Sandra, Putri Ayu Sanjaya, I Made Duwi Septi Roro Liniawati Simatupang, Eliene Br. Siti Maimunah Sitompul, Citra Uli Soma, Yolanda V. A Subagyono, RR Dirgarini Julia Nurlianti Subur P Pasaribu Sulistiawati, Iqlimah Sulistiyawati, Rizki Ramadhani Sumarni, Feni Sunardi Sunardi Susanto, Arnis Budi Syafriyanti, Yuly Theresia Susetyarsi Tri Novianti Tria Annisa Rizky Ulfa Mutia Ulfa Mutia, Ulfa Ulfa, Yulyanti Sartika Wahyu Pratama Wajdie, Farid Winni Astuti Winni Astuti, Winni Yuli Yana