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Specific Histologic Type of Leiomyoma Related to Estrogen Receptor Expression Ni Wayan Armerinayanti; Desak Putu Oki Lestari; I Gde Sastra Winata
WMJ (Warmadewa Medical Journal) Vol 7 No 2 (2022): November 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.2.4601.55-59

Abstract

Uterine Leiomyoma or fibroid is the most common gynecologic benign neoplasm which arising from monoclonal proliferation of smooth muscle cells in uterine wall. Some specific types of uterine leiomyoma, such ascellular leiomyoma, symplastic leiomyoma, mitotically active leiomyoma andmyxoid leiomyomahave different histomorphology from usual type leiomyoma. It also have wide variety of tumors size, but this study found that no correlation between type of leiomyoma and its size. Additional non-invasive therapy that predominantly developed in leiomyoma include many antagonist agents of estrogenic receptor. So, important to determine of estrogen receptor activity before that hormonal therapy prescription.Histopathology parameter that predict estrogen receptor activity in leiomyoma was not well understood. This study also try to correlate between specific histologic type of leiomyoma and estrogen receptor activity. This study was a retrospective crossectional study which analized by pearson chi-square test with p value < 0.05 and CI 95%. Result: There was significant correlation between specific histologic type of leiomyoma and estrogen receptor expression (p=0.007; p<0.05). Key Words: Leiomyoma, Estrogen Receptor
Prevalensi Ekspresi Epidermal Growth Factor Receptor (EGFR) pada Karsinoma Penis Gede Khrisnanda Arya Dharma; Desak Putu Oki Lestari; Ni Wayan Armerinayanti; Ni Luh Putu Eka Kartika Sari
Aesculapius Medical Journal Vol 1 No 1 (2021): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.1.1.2021.38-44

Abstract

Abstract[Prevalence of Epidermal Growth Factor Receptor (EGFR) Expression in Penis Carcinoma] Penile cancer is a malignancy in men, which is the highest in Bali compared to other regions in Indonesia. About 95% of malignancies in the penis are squamous cell carcinoma (SCC). The development of cancer therapy has now reached targeted therapy, while there has not been much research on penile cancer. Targeted therapy based on EGFR overexpression has developed and has been used as individual therapy, especially in lung cancer. This study aims to determine the expression of EGFR in the SCC of the penis. This study is a descriptive observational study to determine the prevalence of EGFR expression from immunohistochemical examination, tumor cells stained with intense brown color surrounding the entire tumor cell membrane. The results of the study of 141 samples of penile squamous cell carcinoma taken from biopsies, partial penectomy, and total penectomy. The prevalence of EGFR expression that was stained positively in penile cancer tumor cells was 8 cases (5.7%) with the highest age distribution in the age group 41-60 years as many as 66 cases (46.8%). Knowledge of EGFR overexpression in penile cancer can be used to reference anti-EGFR administration, especially in advanced penile cancer.
Karakteristik Ibu Hamil Trimester III yang Mengalami Kecemasan dalam Menghadapi Persalinan pada Masa Pandemi Covid-19 di Klinik Kesehatan dan Rumah Bersalin Dewi Laksmi Nabire Papua Ni Ketut Santhiyogi Visnu Wardani; Putu Asih Primatanti; Ni Wayan Armerinayanti
Aesculapius Medical Journal Vol 3 No 2 (2023): June
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.3.2.2023.207-216

Abstract

Covid-19 is an acute respiratory diseasse which was spread to all countries, one of which is Indonesia. One of the impact of this pandemic is causing many restrictions on almost all services, including health services. The maternal mortality rates (MMR) in Papua reached 200 per 100,000 live births. Anxiety is a problem that if not treated immediately can cause problems for the mother and baby, including the occurrence of resistance in the uterine arteries which causes stunted fetal growth. The purposes of this study is to determine characteristics of third trimester pregnant women who experience anxiety in dealing with childbirth during the COVID-19 pandemic at the Dewi Laksmi Nabire Maternity Health Clinic and Maternity Hospital, Papua. This research uses descriptive research method with cross sectional study design with non probability sampling technique purposive sampling method. The sample consisted of 195 third trimester pregnant women who had met the inclusion and exclusion criteria. The data collection instrument used a questionnaire in the form of a google form. Data analysis was performed univariately. The result showed majority of third trimester pregnant women experienced mild-severe anxiety in the age range of 20-35 years (29.3%), had sufficient knowledge (31.1%), received support from their husbands (11.9%), not working (54.3%), primigravida (43.2%), high education level (21.2%), and getting the COVID-19 issue (28.7%). For all pregnant women, it is hoped that this research can be used as informative material that can increase understanding regarding the description level of anxiety on pregnant women that will be giving birth during COVID-19.
Gambaran Kejadian Diare pada Balita di Rumah Sakit Umum Daerah Wangaya Denpasar Komang Yasmika Utami; Ni Wayan Armerinayanti; Anak Agung Oka Lely
Aesculapius Medical Journal Vol 3 No 3 (2023): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.3.3.2023.309-315

Abstract

Abstract [Overview of the Diarrhea Incidence in Toddlers at the Wangaya Regional General Hospital, Denpasar] Diarrhea is a bowel disease with a frequency of 3 or more times per day which is soft, liquid and can be accompanied by blood, mucus, fat, or undigested food particles. Diarrhea is the main cause of death for children under the age of 5 years in Indonesia, due to malnutrition. The severity of diarrheal disease is determined by nutritional status, duration of diarrhea, degree of dehydration, comorbidities and length of stay in hospital. In the province of Bali, the incidence of diarrhea in children under five years includes 1,275 cases and the highest case finding of diarrhea in children under five years is in the city of Denpasar. This study aims to determine the description of diarrheal disease in children under five years at Wangaya General Hospital Denpasar from January 2020 - July 2021. This study is a descriptive study with a cross sectional design. The research subjects were toddlers aged 12-60 months who were selected based on the purposive sampling method. Collecting data using secondary data from the medical records of the Wangaya Regional General Hospital Denpasar, then analyzed using a univariate test through the SPSS computer program. The results showed that all children under five years with diarrhea in Wangaya General Hospital Denpasar experienced acute diarrhea. The majority of toddlers with diarrhea at the Wangaya General Hospital Denpasar experienced mild or moderate dehydration, received less than 5 days of treatment, experienced symptoms of watery bowel movements, vomiting and fever when they entered the hospital and improved when they were brought home. Keywords : diarrhea, duration of diarrhea, degree of dehydration, length of stay in hospital
Karakteristik Vaginal Birth After Caesarean (VBAC) pada Ibu dengan Locus Minoris Resistentiae (LMR) Periode Januari 2017 - Desember 2020 Putu Ayu Bunga Aurellia; Pande Made Ngurah Geriawan; Ni Wayan Armerinayanti
Aesculapius Medical Journal Vol 3 No 3 (2023): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.3.3.2023.292-299

Abstract

Vaginal Birth After Cesarean (VBAC) is a normal delivery process after having previously had a cesarean section. This process is carried out on mothers with former cesarean sections or Locus Minoris Resistant (LMR). The aim of this study was to find out the characteristics of Vaginal Birth After Caesarean (VBAC) in Mothers with Locus Minoris Resistance (LMR) for the period January 2017-December 2020. This study was a retrospective descriptive study with a sample of mothers with LMR who performed VBAC at the Sanjiwani Hospital. Gianyar, BRSUD Tabanan and RS Prima Medika Denpasar which were selected by purposive sampling method that met the inclusion criteria were then presented in tabular form. There were 37 patients out of 48 patients who underwent Trial of Labor After Caesarean (TOLAC) who successfully performed a VBAC with various characteristics, where as many as 32 people (86.5%) with age < 35 years, did not have a history of normal delivery as many as 24 people ( 64.9%), having a cesarean section frequency 1 time as many as 36 people (97.3%), patients with an indication of a previous cesarean section in a breech presentation as many as 14 people (37.9%), with a delivery distance of > 24 months as many as 37 people ( 100%) and gave birth to babies with a birth weight of 2500-4000 grams as many as 36 people (97.3%).
Hubungan Stres dengan Motivasi Belajar pada Siswa SMA Negeri 1 Ubud Kadek Berliantara; Putu Asih Primatanti; Ni Wayan Armerinayanti
Aesculapius Medical Journal Vol 4 No 2 (2024): June
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.2.2024.189-193

Abstract

[The Relationship between Stress and Learning Motivation in Ubud 1 Public High School Students] Stress refers to mental and emotional disturbances that can arise from both internal and external factors. Learning motivation is a desire that oroginates within the student and lead to various learning activities. Due to the lack of previous research on this topic at SMA Negeri 1 Ubud, it is crucial to conduct this study in order to gather relevant , which could potentially benefit the school. This research can help the school prevent the factors that cause stress in students and increase the learning motivation. this study used descriptive analytic with a cross-sectional approach. This research was conducted at SMA Negeri 1 Data was collected using Perceived Stress Scale questionnaire (PSS-10) and Motivated Strategies for Learning Questionnaire (MSLQ-18). Furthermore, data analyzed both univariately and bivariately using the SPSS 25th version and Spearman test method, considering the analysis significant if the p value is less than 0.05. The univariate analysis revealed that the majority of students were 16 years old (36.2%), with a majority of female students (55.7%) and a majority of class XI students (33.8%). The Spearman correlation test's bivariate analysis yielded a significance value of 0.000, with a significant level of 0.05. The correlation coefficient, which stands at 0.241, indicates a weak relationship. The negative correlation coefficient number indicates an opposite relationship between the two variables, suggesting that higher stress levels lead to decreased learning motivation among SMA Negeri 1 Ubud students.
Karakteristik Pencetus Hiperbilirubinemia pada Neonatus di Rumah Sakit Daerah Mangusada Badung Bali Periode 2022-2023 I Putu Agung Dhrestaketu Sumedang; Romy Windiyanto; Ni Wayan Armerinayanti
Aesculapius Medical Journal Vol 4 No 3 (2024): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.3.2024.303-312

Abstract

World Health Organization in 2019 reported that as many as 7000 newborns died in the world, while in Indonesia as many as 185 newborns died per day with an IMR of 15/1000 live births. In Mangusada Badung regional hospital, the incidence of neonates with hyperbilirubinemia in 2017 was 1100 neonates, in 2018 there were 1151 neonates with hyperbilirubinemia and in 2019 there were 1075 babies with neonatal jaundice. Hyperbilirubinemia is an increase amount of bilirubin that accumulates in the blood, characterized by total serum bilirubin levels ? 5 mg/dL (86 µmol/L). This study aims to determine the characteristics of triggers of hyperbilirubinemia in neonates at Mangusada Badung Regional Hospital Bali 2022-2023. This study used medical records of hyperbiliribinemia neonates at Mangusada Badung Regional Hospital Bali in periode 1st Januari-31st December 2023 to collect data. Then analysed univariat with descriptive analysis. The results of this study were the characteristics of the dominant variables including the age of the mother at risk (76,4%), male gender (62,2%), neonates with induction of labor (60,0%), premature neonates (81,3%), LBW (81,3%), asphyxia (95,5%), breastfeeding neonates (69,7%), and caesarean delivery method (68,5%). This study can be an additional information about the characteristics of hyperbilirubinemia triggers in neonates so that prevention can be done.
Penyuluhan Keberlanjutan Kegiatan Inspeksi Visual Asetat (IVA) dan Pap Smear Bidan Puskesmas Pembantu Kelurahan Kesiman Ni Wayan Armerinayanti; Oki Lestari Desak Putu
Warmadewa Minesterium Medical Journal Vol. 4 No. 2 (2025): Mei 2025
Publisher : Warmadewa University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmmj.4.2.2025.171-175

Abstract

Kanker serviks merupakan salah satu jenis kanker yang paling umum menyerang wanita di Indonesia. Deteksi dini melalui pemeriksaan Inspeksi Visual dengan Asam Asetat (IVA) dan Pap Smear adalah langkah penting dalam pencegahan dan pengobatan kanker serviks. Namun, kesadaran dan pengetahuan masyarakat tentang pentingnya pemeriksaan rutin masih rendah. Kader puskesmas memiliki peran strategis dalam menyebarluaskan informasi kesehatan dan mendorong masyarakat untuk melakukan pemeriksaan dini. Kelurahan Kesiman, seperti banyak daerah lainnya, menghadapi tantangan dalam meningkatkan kesadaran dan partisipasi masyarakat dalam program deteksi dini kanker serviks. Banyak wanita yang belum memahami pentingnya pemeriksaan IVA dan Pap Smear, serta takut atau enggan untuk melakukannya. Kader puskesmas, sebagai ujung tombak pelayanan kesehatan di masyarakat, memerlukan pengetahuan dan keterampilan yang memadai untuk memberikan edukasi dan motivasi kepada warga. Hasil pengabdian ini adalah mitra PKM menunjukkan peningkatan pemahaman dan komitmen mengenai pentingnya pelaksanaan pelayanan deteksi dini kanker serviks di wilayah kerja mitra. Demi keberlanjutan program berikutnya, akan lebih baik jika bersama-sama disusun alur rujukan temuan deteksi abnormal.
Pengembangan Penggunaan Wearable Device untuk Monitoring Kondisi Kardiovaskular Pasien Gagal Jantung Gede Bagus Gita Pranata; Ni Wayan Armerinayanti
Warmadewa Minesterium Medical Journal Vol. 4 No. 3 (2025): September 2025
Publisher : Warmadewa University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmmj.4.3.2025.233-237

Abstract

Bali adalah salah satu daerah dengan penduduk yang padat. Data epidemiologi Riskesdas (2020) menunjukkan prevalensi penyakit gagal jantung di Provinsi Bali khususnya Kabupaten Gianyar masih sangat tinggi yakni 15.446 jiwa. Sebagai mitra, kami mengajak dari tim PKRS RSUD Sanjiwani yang biasa bertugas sebagai ujung tombak promosi edukasi kesehatan. Dibawah pimpinan bapak Agus Lingga tim PKRS memiliki beberapa masalah promkes khususnya di bidang jantung dan pembuluh darah dimana kasusnya semakin bertambah banyak dan beberapa masuk ke instalasi gawat darurat dalam kondisi yang sudah kompleks. Sehingga diperlukan metode pemantauan kondisi kardiovaskular yang real time dapat diketahui oleh pasien atau keluarganya. Tim PKM terdiri dari 5 orang (termasuk mahasiswa) berperan memberikan edukasi, contoh dan cara penggunaan wearable device yang sederhana dapat terhubung ke ponsel penderita maupun keluarga untuk memantau beberapa tanda vital pasien. Metode pengabdian ini berupa focus group discussion dengan tujuan pasien dan keluarganya memahami cara pemakaian wearable device secara spesifik untuk pemantauan tanda vital. Teknologi ini dapat memberikan data yang berharga mengenai denyut jantung, ritme jantung, saturasi oksigen, dan parameter kardiovaskular lainnya, sehingga dapat membantu dalam pengambilan keputusan medis yang lebih cepat dan tepat. Jumlah pasien yang terlibat sekitar 50 orang dengan masing-masing grup berjumlah 10 orang. Kriteria pemilihan adalah pasien atau keluarganya yang memiliki wearable device. Tahap pertama yakni ceramah edukasi berturut selama 3 hari sembari memilih pasien yang memiliki device. Tahap kedua melakukan FGD mengenai pemahaman dan cara pemakain, tahap ketiga yakni pemantauan. Hasil dari pelaksanaan Program Kreativitas Mahasiswa (PKM) ini menunjukkan bahwa mitra PKM mengalami peningkatan pemahaman dan komitmen terhadap pentingnya pelaksanaan monitoring gejala dan tanda vital pada pasien dengan gagal jantung. Hal ini dibuktikan melalui hasil evaluasi berupa pre-test dan post-test, yang menunjukkan peningkatan nilai sebesar 25 poin. Demi keberlanjutan program berikutnya, akan lebih baik jika bersama-sama disusun alur rujukan temuan deteksi abnormal.
Pengabdian Masyarakat di Pura Penataran Agung Margo Wening, Sidoarjo Putu Nita Cahyawati; Asri Lestarini; Ni Wayan Armerinayanti
Warmadewa Minesterium Medical Journal Vol. 5 No. 1 (2026): Januari 2026
Publisher : Warmadewa University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmmj.5.1.2026.66-70

Abstract

Pura Penataran Agung Margo Wening merupakan pura pertama di Kabupaten Sidorjo yang diresmikan pada tahun 1991. Pura ini berada di Desa Balonggarut Kecamatan Krembung Kabupaten Sidoarjo. Pendirian pura ini bertujuan sebagai tempat beribadah umat Hindu di Desa Balonggarut dan daerah sekitarnya. Dalam proses pembangunannya, terdapat beberapa hambatan mulai dari keterbatasan dana hingga situasi politik Indosesia saat itu. Proses Pembangunan pura ini sempat terhenti beberapa kali, namun dilanjutkan kembali pada tahun 1990. Kegiatan pengabdian bertujuan untuk memberikan edukasi kesehatan khususnya perilaku hidup bersih kepada pengelola dan warga setempat. Kegiatan pengabdian ini dilakukan melalui beberapa metode yaitu koordinasi, pelaksanaan kegiatan, dan evaluasi. Kegiatan hadiri oleh tim pengabdian disertai dengan kelian Pura, Perhimpunan Hindu Dharma Indonesia (PHDI) Kabupaten Sidoarjo yang diwakilkan oleh sekretaris PHDI, serta pengelola pura. Berdasarkan hasil evaluasi, kegiatan dilaksanakan sesuai dengan rencana dan disambut baik dengan seluh pihak yang terlibat. Pelaksanaan kegiatan dilakukan sebanyak satu kali, demikian pula dengan pemberian bantuan hibah. Ditemukan bahwa 80% mitra mampu menjawab pertanyaan lisan dengan tepat. Hal ini melampaui target yang telah ditetapkan yaitu 70%. Mitra berharap agar kegiatan ini terlaksana secara rutin sehingga upaya pengembangan pura menjadi lebih optimal.
Co-Authors Ade Dwi Mahendra Agung Brahmanthya Nadine Kepakisan Agus Santosa Anak Agung Oka Lely Analysa - Artha, I Gusti Alit Asri Lestarini Astuti, Ni Luh Putu Vina Juni Cahyawati, Putu Nita Christo Timothy Mamangdean Desak Putu Oki Lestari Gde Candra Yogiswara Gede Bagus Gita Pranata Gede Khrisnanda Arya Dharma Gede Khrisnanda Arya Dharma I Gde Sastra Winata I Gede Krisna Arim Sadeva I Gede Wikania Wira Wiguna I Gusti Ngurah Fajar Viwakananda I Ketut Mulyadi I Komang Ardhika Gunawan I Komang Raditya Putra Pratama I Putu Agung Dhrestaketu Sumedang I Wayan Juli Sumadi I Wayan Suwarna Kadek Agus Kurniawan Kadek Berliantara Kadek Berliantara Kadek Meryndha Kumala Tungga Ketut Mulyadi Komang Indra Parama  Arta Komang Yasmika Utami Komang Yasmika Utami Luh Gde Evayanti Luh Putri Wulandari dewi Luh Putu Iin Indrayani Maker Made Bramastya Nugraha Teja Kusuma Mulyawan Made Intan Ryani Putri Made Intan Ryani Putri Ni Ketut Santhiyogi Visnu Wardani Ni Ketut Santhiyogi Visnu Wardani Ni Luh Putu Eka Kartika Sari Ni Luh Putu Eka Kartika Sari Ni Putu Diah Witari, Ni Putu Ni Putu Eka Widiantari Pande Made Ngurah Geriawan Perdana, I Gede Sukma Okta Putu Ari Shanti Dewi Putu Asih Primatanti Putu Asih Primatanti Putu Ayu Bunga Aurellia Putu Ayu Bunga Aurellia Putu Indah Budi Apsari dewi Putu Mirah Wahyu Subagia Putri Putu Nita Cahyawati PUTU SARASWATI LAKSMI DEWI Riasa, I Nyoman Putu Romy Windiyanto Rusni, Ni Wayan Sari, Ni Luh Putu Eka Kartika Sri Ratna Dewi Suka Astini, Dewa Ayu Agung Alit Wardana, Ni Komang Sara Kusuma