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Debie Rizqoh
Departemen Mikrobiologi Dan Imunologi, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Bengkulu
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Journal : Medical and Health Science Journal

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Kinetics IgM and IgG SARS-CoV-2 in Recovery patients with Negative Evaluation RT-PCR Endang, Jusup; Sariyanti, Mardhatillah; Triana, Dessy; Rizqoh, Debie; Enny, Nugraheni
Jurnal Ilmu Kesehatan dan Kesehatan Vol 7 No 02 (2023): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v7i02.4359

Abstract

Background: Coronavirus is the major pathogens at human respiratory system. The antibody is a response infected patients largely not clearly. We need to understanding of antibody responses to great diagnosis and treatment studies. Objective: In this article the objective is to describe that kinetics of IgM and IgG SARS-CoV-2 in recovery patients. Method: Cohort study used a total 19 subjects who had negative evaluation RT-PCR after confirmed. IgG and IgM of SARS-CoV-2 were detected by IFA (Immuno fluorosence assay) used serum. Serum were collected 3 times after 1 month, 2 month and 4 month negative evaluation RT-PCR We profiled the serological responses (IgM and IgG) to SARS-CoV-2. Result: Majority the IgM SARS-CoV-2 post evaluation RT-PCR were very low after 1,2,4 month negative evaluation. IgG SAR-CoV-2 patients post negative evaluation RT-PCR decreased after 4 months. The level IgM and IgG level increase at first week and decrease after 12 weeks. Conclusion: IgM level lower than IgG level overtime. Quantitative IgG and IgM detection could be point of diagnosis and manifestation.
Co-Authors Ade Tiur Rumondang Ade Tiur Rumondang Adiansyah Ahmad Fandi Alvi Jalilul Hakim Ambarsarie, Riry Amelia, Aisyah Annelin Kurniati Annelin Kurniati Arifani, Novita Ashan, Hesty Rhauda Athalia , Nabila Wine Atik Prihatiningrum, Atik Atiqah, Rissya Febiona Azella Chika Fauzia Besly Sinuhaji Besly Sinuhaji Besly Sinuhaji Dendrinson Purba Dendrinson Purba Dessy Triana Dessy Triana Dessy Triana Diah Ayu Aguspa Dita Dian Handayani Djatmiko, Ellen Maidia Ellen Maidia Djatmiko Ellen Maidia Djatmiko Elvira Yunita Elvira Yunita Endang, Jusup Enny Nugrahaeni Enny Nugrahaeni Enny Nugraheni Enny Nugraheni Enny Nugraheni Enny, Nugraheni Ety Febrianti Ety Febrianti Fadlika, Rizki Fahira, Dita Fandi, Ahmad Fauzia, Azella Chika Febrianti, Ety Febrina, Olivia Putri Grace Junita Bate'e Gunasari, Lala Foresta Valentine Hakim, Alvi Jalilul Hamka Ismuda Hestina Hestina Iqbal, Maulana Jusup Endang Kumala, Wulan Okta Kurniati, Annelin Laudy, Nabila Putri Mardhatillah Sariyanti Mardhatillah Sariyanti Mardhatillah Sariyanti Mardhatillah Sariyanti Meidiyanti, Prima Mulya Sundari Mulya Sundari Mulya Sundari Mulya Sundari Mulya Sundari Mulya Sundari Nabilah, Putri Syifa Nikki Aldi Massardi Noor Diah Erlinawati Novita Arifani Nugraheni, Enny Nur Fitri Ocktaviani, Risti Dwi Oktavia Salsadillah Putri Oktavia Silalahi Oktoviani Oktoviani, Oktoviani Pratiwi, Ulfa Hanum Putri Maulida Rachmawati, Indah Dwi Ramadhani, Abdah Zhafirah Rizkianti Anggraini Roina Sitanggang Roina Sitanggang Sariyanti, Mardhatillah Sipriyadi Suryani, Utari Hartati Umar, Liya Agustin Utari Hartati Suryani Utari Hartati Suryani Wulan Okta Kumala