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Journal : Odonto dental journal

STUDY ANALYSIS OF ORAL TUBERCULOSIS LESION IN SOUTH KALIMANTAN, INDONESIA Maharani Laillyza Apriasari; Monita Valentine Silalahi; Isnur Hatta; Juliyatin Putri Utami
Odonto : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (730.641 KB) | DOI: 10.30659/odj.7.1.1-8

Abstract

Background: Tuberculosis is an infectious disease which is the second-largest cause of death in the world after HIV / AIDS. Tuberculosis caused by Mycobacterium tuberculosis that usually attacks the lungs but can manifest in the oral mucosa. Clinical manifestations of oral Tuberculosis related to age, sex, duration of treatment, systemic disease, and Multi-Drug Resistant therapy. There is no research on descriptive studies of oral manifestations of tuberculosis patients in South Kalimantan, specifically in Banjarmasin. This study aims to analyze the clinical manifestations of oral Tuberculosis descriptively in South Kalimantan, Indonesia. Method: This was a descriptive analysis with cross-sectional study design, based on history and clinical oral examination. It was used 30 respondents by purposive sampling method. Data were analyzed by Chi-square (p<0.05). Results: During treatment, it showed the correlation between xerostomia and systemic disease (diabetes mellitus and HIV/AIDS) are (p=0.007) and a correlation between xerostomia and duration of treatment (p=0.024). The correlation between candidiasis and systemic disease (p=0.024). The correlation between angular cheilitis and age, sex, duration of treatment, systemic disease, and Multi-Drug Resistant therapy (p>0.05). The clinical manifestations of oral Tuberculosis are xerostomia, candidiasis, and angular cheilitis.Conclusion: The duration of treatment and the systemic diseases are associated with xerostomia and candidiasis in the oral cavity of TB patients.
Antibacterial, Antifungal And Subchronic Toxicity Test Of Ficus Deltoidea Jack Leaves Extract Apriasari, Maharani Laillyza; Adhiya, Geyanina Melda; Wasiaturrahmah, Yusrinie; Utami, Juliyatin Putri; Firdaus, I Wayan Arya Krishnawan; Pramitha, Selviana Rizky
Odonto : Dental Journal Vol 12, No 1 (2025): April 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.12.1.19-28

Abstract

Background: Ficus deltoidea Jack is a plant that is often used as herbs medicine because of secondary metabolites such as alkaloids, phenolics, flavonoids, and steroids. This study aims to determine the activity of antibacterial, antifungal and toxicity effect of Ficus deltoidea Jack leaves (FDLE) extract. Method: Pure experimental study with a posttest-only design with a control group design. The in vitro test by dilution methods using Staphylococcus aureus and Candida albicans.  The toxicity test used 16 male Rattus novergicus divided into four group consist a control group and three treatment group given FDLE doses with 1,250, 2,500, and 3,750 mg/kgBW. The treatment applied 2x1 ml FDLE every 24 hours orally for 28 days. Result: The MIC value and the MBC value of FDLE againts S. aureus were 8% and 10%, respectively. While, MIC and MBC value on C. albicans has similar value about 25%. The mean results of kidney toxicity test were still in the normal range. There was a significant difference in the results of the Kruskall Wallis test for urea (p<0.05), while there was no significant difference in the results of urea and creatinine level (p>0.05). Conclusion: There was antibacterial and antifungal efficacy of FDLE. Also, there was no toxic effect of giving FDLE at doses of 1,250, 2,500, and 3,750 mg/kgBW was showed on urea and creatinine normal level.
Co-Authors Adhiya, Geyanina Melda Agung Satria Wardhana Ainna Dewi Iriani Amalia, Aysca Fakhira Amy Nindia Carabelly Anisa Novia Farrasti Annisa Noviany Aprilyani, Nur Arifin, Rahmad Aspriyanto, Didit At-Thoyyar, Aila Azminida, Dhiya Salma Baitullah, Muhammad Akbar Bambang Setiawan Beta Widya Oktiani Budiarman, Andi Azizah Maulidia Dewi Indah Noviana Pratiwi, Dewi Indah Noviana Dewi Nurdiana Dewi Purboningsih Dewi Puspitasari Dewi Puspitasari Diana Lyrawati Diana Wibowo Erika Norfitriyah Eriwati, Yosi Kusuma Erni Marlina Febriansyah, Muhammad Firda Damayanti Firdaus, I Wayan Arya Krishnawan Fransiska Uli Arta Panjaitan Gita Puspa Ningrum Hadi Waskito Haluanry Doane Santoso Hatta, Isnur Ichrom Nahzi, Muhammad Yanuar Idhafi, Nasrul Ika Kusuma Wardani Jatmiko, Habibi Naufal Kelana, Adhytya Suryo Krishnawan Firdaus, I Wayan Arya Kurnianingsih, Nia Lena Rosida Maghfirah, Yolanda Sajjida Maharani Laillyza Apriasari Maharani Laillyza Apriasari Maria Tanumihardja, Maria Maulida, Novi Dwi Melisa Budipramana, Melisa Milka Widya Sari Mira Hadistiana Monita Valentine Silalahi Muhammad Adeya Herdira Putra Muhammad Akbar Baitullah Muhammad Hasanu Reksi Muhammad Reza Faisal, Muhammad Reza Muhammad Rizal Bima Saputra Nahzi, Yanuar Ichrom Nanda Putri Arini Nia Kurnianingsih Nida, Raihatun Nisa Fachrizha Munier Norfitriyah, Erika Novi Dwi Maulida Novia Damayanti Nur Tsaniya, Gusti Erysa Nurdiana Nurdiana Oktiani, Beta Widya Panghiyangani, Roselina Pramitha, Selviana Rizky Priyawan Rachmadi Rahmad Arifin Ramadhaniyah, Nur Roselina Panghiyangani Safa Muzdalifah Salsabila, Namira Fathya Sandra Bhakti Mafriana Sari, Galuh Dwinta Sari, Milka Widya Sarifah, Norlaila Sherli Diana Tri Putri, Deby Kania Wydiamala, Erida Yunike Christanti Yusrinie Wasiaturrahmah