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Characteristics, Management, and Mortality Differences in Pediatric Patients with Pleural Effusion Before and During the COVID-19 Pandemic Dya Mulya Lestari; Finny Fitry Yani; Rinang Mariko
Eduvest - Journal of Universal Studies Vol. 6 No. 8 (2026): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v6i8.53379

Abstract

The research aims to determine the differences in characteristics, management, and mortality of pediatric patients with pleural effusion before and during the Covid-19 pandemic; A cross-sectional study of 60 patient from February 2018 to March 2022 at RSUP. Dr. M. Djamil Padang, obtained through random sampling. Data analyse using univariate and bivariate, with bivariate analysis using Chi-square Test with significance at p <0.05; Results: Out of 60 samples, an increased number of patients aged 2-5 years during the Covid-19 pandemic (23.3%) was found, complaints before hospital admission >4 weeks were higher before Covid-19 at 23.3% (p <0.05), LDH levels in pleural effusion fluid during Covid-19 were higher at 5,277 + 10,664 (p <0.05). Staphylococcus aureus from blood cultures was higher during Covid-19 (16.7%). The use of CPAP before and during Covid-19 was 20% vs 16.7%, and ventilator use was 33.3% vs 36.7%, the most commonly used antibiotics were Ampicillin (63.3% vs 46.7%) and Gentamicin (50.0% vs 33.3%). Patient mortality was higher during Covid-19 (36.7%), although not statistically significant (p> 0.05); There were significant differences in the duration of complaints before hospital admission and LDH levels in pleural effusion fluid, but the management and mortality did not show significant differences.
DIFFERENCES IN CLINICAL AND LABORATORY PRESENTATIONS IN PEDIATRIC TUBERCULOSIS PATIENTS WITH AND WITHOUT HIV CO-INFECTION Iffa Muthiah; Syandrez Prima Putra; Rinang Mariko
SINERGI : Jurnal Riset Ilmiah Vol. 3 No. 10 (2026): SINERGI : Jurnal Riset Ilmiah, Oktober 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v3i10.3085

Abstract

Tuberculosis (TB) remains one of the top 10 causes of death in children worldwide, particularly among those with HIV coinfection. This study aimed to determine differences in clinical and laboratory presentations between pediatric TB patients with and without HIV coinfection at Dr. M. Djamil Padang General Hospital. This cross-sectional observational study used secondary data from pediatric TB patients treated between 2017 and 2021. Clinical presentations (cough, fever, decreased appetite, weight loss, malnutrition, lymphadenopathy, dyspnea, oral candidiasis, diarrhea, and extrapulmonary TB) and laboratory parameters (hemoglobin, leukocyte count, platelet count, and differential leukocyte count) were analyzed. Among 106 patients, 20 (18.86%) had HIV coinfection. The most common clinical presentations were cough (93.4%), fever (86.6%), and malnutrition (74.5%). Anemia was found in 70.8% of patients. Significant differences in HIV-coinfected children included oral candidiasis (60%; p<0.001), lymphadenopathy (40%; p=0.006), diarrhea (45%; p<0.001), weight loss (75%; p=0.001), and anemia (95%; p=0.018). These findings suggest that clinical and laboratory presentations can help screen for HIV coinfection among pediatric TB patients in healthcare settings.