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Indonesian Society of Respirology Position Paper on Lung Cancer Control in Indonesia Andarini, Sita; Santoso, Andintia Aisyah; Arfiansyah, Mochammad Aris; Syahruddin, Elisna; Zaini, Jamal; Putra, Andika Chandra; Kurniawan, Ferry Dwi; Ermayanti, Sabrina; Soeroso, Noni Novisari; Munir, Sri Melati; Infianto, Andreas; Setijadi, Ana Rima; Setyawan, Ungky Agus; Wulandari, Laksmi; Haryati, Haryati; Jasminarti, Ida Ayu; Hidayat, Moulid; Santoso, Arif
Jurnal Respirologi Indonesia Vol 44 No 4 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i4.884

Abstract

Lung cancer is a major health concern in Indonesia due to its increasing prevalence, late-stage diagnosis, younger population, and high mortality. Addressing this issue requires nationwide implementation of comprehensive lung cancer control, which includes risk reduction and prevention strategies, focusing on tobacco control and air pollution mitigation. Screening with low-dose computed tomography (LDCT) and early detection in symptomatic patients, along with TB screening programs and all non-communicable diseases, is strongly recommended to enhance early case findings, treatment effectiveness, and overall patient outcomes. A multidisciplinary team (MDT) approach is important to ensure accurate diagnosis and comprehensive care. Moreover, the integration of palliative care at the early stages of advanced lung cancer is vital, focusing on symptom management and enhancing the quality of life for patients. While national guidelines are available for the diagnosis and treatment of lung cancer, significant disparities in healthcare access remain across Indonesia. Thus, it is essential to improve universal health coverage and referral systems to guarantee equal access to lung cancer care for patients at all levels through advocacy and ease of access.
Aspergillosis in Lung Cancer: A Narrative Literature Review Yarsy, Pofi Risanti; Sri Melati Munir
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 3 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i3.935

Abstract

Aspergillosis is one of the complications of lung cancer and lung cancer treatment. Diagnosis of Aspergillosis in lung cancer, in general, is still a challenge because clinical symptoms and examination results are not typical, and risk factors often go unnoticed. To simplify the diagnosis of Aspergillosis, several criteria have been created based on the patient's condition, clinical and radiological features, and mycological laboratory examination. Doctors' vigilance still needs to be increased, examination facilities are still limited in certain cities, and diagnostic services have not been integrated, so management is not optimal. This literature review aims to increase doctors' knowledge and awareness regarding aspergillosis in lung cancer, which is an important step to improve the appropriate management of this disease.
The effect of systemic chemotherapy on hematological profiles in lung cancer patients Amarudin, Amarudin; Munir, Sri Melati
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 1 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i1.3610

Abstract

Background: Cancer is a disease characterized by uncontrolled cell growth in one or both lungs originating from epithelial cells. In Indonesia, lung cancer ranks fourth among all cancer types and is the second leading cause of death after cardiovascular diseases. Management of lung cancer involves various therapeutic modalities, including surgery, radiotherapy, chemotherapy, and combination therapy. Certain chemotherapeutic agents, such as cisplatin and carboplatin, are known to have a narrow therapeutic index and high toxicity, so inappropriate regimen selection or dosing may result in serious adverse effects or even death. All chemotherapy agents carry the potential for toxicity, including both hematological and non-hematological effects, with hematological toxicities commonly manifesting as anemia, leukopenia, and thrombocytopenia of varying severity. Objective: This study aimed to determine the hematologic profile in patients after chemotherapy. Methods: This study was a descriptive research with a cross-sectional design using a total sampling technique. During the August-December 2023 period, 36 lung cancer patients met the inclusion criteria at Arifin Achmad Hospital, namely lung cancer patients with adenocarcinoma or squamous cell carcinoma who underwent advanced chemotherapy with a cycle of 21 days in the August-December 2023 period. Results: Of the 36 patients, 29 (80.56%) were male. The highest age of patients undergoing chemotherapy was ≥ 40 years (94.44%). Changes in the hematological profile after chemotherapy occurred in 14 patients (38.89%), with the most common hematological profile being anemia. Conclusion: The use of chemotherapy regimens can cause changes in the hematologic profile, including anemia, leukopenia, and thrombocytopenia.