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All Journal International Journal of Public Health Science (IJPHS) Sainteks JURNAL GIZI INDONESIA AGROTEKBIS Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing) Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Farmasi Sains dan Komunitas JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JPI Jurnal Kesehatan Komunitas JECCE (Journal of Early Childhood Care and Education) Martabe : Jurnal Pengabdian Kepada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) JFIOnline Jurnal Basataka (JBT) Diklat Review : Jurnal manajemen pendidikan dan pelatihan Jurnal Abdi Insani JURNAL AKUNTANSI Jurnal Wahana Pendidikan Jurnal Ilmiah Pharmacy Journal of Agri-Food Science and Technology (JAFoST) Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Sains dan Praktis Journal of Halal Science and Research Jurnal Primagraha Jurnal Dedikasi untuk Negeri JIMPI: Jurnal Inovatif Manajemen Pendidikan Journal of Public Health and Pharmacy Asian Journal of Social and Humanities
Nurkhasanah Nurkhasanah
Universitas Ahmad Dahlan
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : International Journal of Public Health Science (IJPHS)

 1 
The Effect of Ethanolic Extract of Roselle (Hibiscuss sabdariffa L) on Increasing SOD Activity Abdul Rahman W; Nurkhasanah Nurkhasanah; Nanik Sulistyani
International Journal of Public Health Science (IJPHS) Vol 5, No 1: March 2016
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.947 KB) | DOI: 10.11591/ijphs.v5i1.4773

Abstract

Free radicals were reactive species caused oxidation of lipids membrane and DNA. Superoxide dismutase (SOD) is one of the primary antioxidants to inhibit free radicals. The purpose of this study was to determine the effect of ethanol extract of roselle calyx on SOD enzyme activity of the Sprague Dawley (SD) rats induced by 7.12-dimethylbenzen[a]anthracene (DMBA). The animals age of four weeks divided in to five groups, groups I were normal group. Group II is the negative control group only induced by DMBA 75 mg/kgBW; and group III ,IV , and V were treatment groups that treated by ethanolic extract of roselle calyx at dose of 10, 50 and 100 mg/kgBW/day for 7 days. After treatment with roselle, animals were induced by DMBA 75 mg/kgBW. On day 8 after DMBA induction, animals were fasted for 16 hours and blood was collected to measured SOD activity. Data were analyzed using One Way Analysis Of Variance (ANOVA) and LSD (P <0.05). The result showed the significancies on increasing of SOD activity at 10 mg/kgBW (50.87±1.98), 50 mg/kgBW (69.98±3.58) and 100 mg/kgBW (73.01±6.95) compared with DMBA (43.74±1.95) (p<0,05).
The antihyperlipidaemic and hepatoprotective effect of Ipomoea batatas L. leaves extract in high-fat diet rats Nurkhasanah Mahfudh; Nanik Sulistyani; Muhammad Syakbani; Athifah Candra Dewi
International Journal of Public Health Science (IJPHS) Vol 10, No 3: September 2021
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v10i3.20777

Abstract

The administration of high-fat diets can increase the body's lipid level and damage the organs. Purple sweet potato leaf (Ipomoea batatas L.) was reported as an antioxidant against free radicals. This study aimed to observe the sweet potato leaf extract's activity on decreasing lipid profile and hepatoprotective effect in high-fat diet fed rats. The treatment animals were divided into five groups, namely normal control, high-fat diet (HFD) control, the treatment group of purple sweet potato leaf extract (SPLE) doses 100 mg/kg BW, 200 mg/kg BW and 400 mg/kg BW which fed with high-fat diet for 14 days and SPLE for 28 days. After treatment was completed, the blood was collected for the detection of cholesterol, triglyceride, serum glutamic oxaloacetic transaminase (SGOT), and serum glutamic pyruvate transaminase (SGPT). After that, the animals were sacrificed, and a liver histopathology observation was conducted using Haematoxylien and Eosin staining. The result showed a significant decrease in cholesterol and triglyceride levels (p≤0.05) compared to the negative group in all treated groups. The SGOT and SGPT enzymes in all of treatment groups were also found to decrease compared with HFD control. The result was confirmed by the histopathological observations. The finding suggested the potency of SPLE for antihyperlipidaemic and hepatoprotective agent.
Co-Authors A'Yun, Qurotul AA Sudharmawan, AA Abdul Rahman Wahid Ade Irawan Adelita, Audrey Adiba, Thoriq Agus Nasihin Ahmad, Aunillah Akrom, Akrom Albab, Farah Qistih Alif Muarifah Amalya Nurul Khairi Amini, Nurul Fajar Anisah, Retnani Anjani, Arlian Sherly Aprilia, Kartini Aryastuti, Nurul Athifah Candra Dewi Ayu Shabrina Baroroh, Erli Carmel Meiden Chasanah, Hikmah Rochimatul Christin Angelina Febriani Daipadli Daipadli Deni Firmansyah Dianingsig, Dianingsih Easter Yanti, Dhiny Elya Zulfa, Elya Farah Qistih Albab Fitri Usfa, Hafiratul Fitrilya Mustikahati Yusuf, Fitrilya Mustikahati Flora Pasaru Gabrilla Yusuf, Ghina Harni, Harni Humaya, Humaya Ika Dyah Kumalasari Ika Kumalasari Imas Juidah Irawati, Riana Jailani, Muhammad Taufiq Bin Mohd Jayadinata, Asep Kurnia Jihad Lukis Panjawa Kariza, Alifia Ninda karmila karmila Kautsar, Akhmad Khairi, Amalya Nurul Laela Hayu Nurani Lola Angelita Lolita Sary Lovrina Rahmi Zulkarmen Mahdi, Lukman Maknun, Lu'lu'ul Meta Safitri Moch. Saiful Bachri Muhammad Syakbani Murinto Murinto Nada, Rafa Nanik Sulistyani Neni Fidya Santi Nihayati, Nihayati Ningsih, Nur Cahyati Nofa Risma Azis Nora Afriza, Zelda Nugroho, Bondan Nur Ahmad, Nur Nurul, Amalya Ofa Suzanti Betha Pramudianti, Ulfa Rahma Puri, Putri Ratna Rabiatul Adawiyah Rahman, Ika Ristia Ramadani, Cahya Ricke Desyratnaputri Rizka Indri Arfianti Rizky H. Mawardi Rostika, Rostika Sabrina Dahlizar Sapto Yuliani Saputri, Ginanjar Zukhruf Sari Manulang, Chanita Sepitriani, Sepitriani Siti Pandanwangi TW Siti Pandawangi TW Siti Sarifah Soedjono Soedjono Tri Yanuarto Tri Yanuarto Utami, Zhazha Zetira W, Ratna Kurnia Winata, Nana Triana Wiwin Lismidiati Wulandari, Dita yesi budiarti, yesi Yuni Anggraeni Yunni Arnidha, Yunni Zuniarto, Ahmad Azrul