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Metta Octora
Departemen Biostatistika dan Kependudukan Fakultas Kesehatan Masyarakat Universitas Airlangga
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Public Health

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Journal : Jurnal Biologi Tropis

 1 
Characteristics of Facial Skin Biophysical Parameters Among Medical Students in University of Mataram Hidajat, Dedianto; Sari, Dian Puspita; Octora, Metta; Wedayani, Anak Agung Ayu Niti
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9195

Abstract

Various studies have been widely published regarding the efficacy and adverse effects of facial care products with research populations from adolescent to young adults. However, it is necessary to first identify the characteristics of this parameters in the local population. The purpose of this study is to obtain an overview of the characteristics of the biophysical parameters of facial skin in a population of teenagers and young adults who tend to be active indoors, especially UNRAM medical students. This was an analytical observational study with a cross-sectional approach. Participants filled out questionnaires and followed procedures for examining facial skin biophysical parameters. The results of this study showed that from 147 participants, the average TEWL level was 8,99 g/h/m2; mean degree of erythema was 262,5; the average melanin index was 192,1 and the average sebum level was 192,1. Statistical analysis found that there was an association between gender and all facial skin biophysical parameters, a relationship between age and sebum levels and a relationship between daily activities in an air-conditioned room and the degree of erythema. With the data presented in this study, research related to facial skin biophysical parameters in similar populations can be developed further.
Profile of Gram-Negative Bacteria Extended Spectrum Beta Lactamase Esbl in The Caecum of Broiler Chickens Indratama, I Nyoman Yudayana; Rosyunita, Rosyunita; Hasbi, Nurmi; Octora, Metta; Rizqullah, Rifqi
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.10027

Abstract

Antimicrobial Resistance (AMR) is a global problem that causes increased morbidity, mortality, and healthcare costs. AMR arises from the irrational use of antibiotics in medicine and agriculture. This study aims to determine the profile of Gram-negative ESBL bacteria living in the cecum of broiler chickens. This study is a descriptive exploratory study using 5 chicken cecum samples taken from the Pagesangan market in Mataram city. The obtained bacteria were calculated by placing them on Macconkey agar media to count bacterial colonies. The results of this study showed that 20.1% of bacteria in the chicken cecum could grow on Macconkey media mixed with cefotaxime. Meanwhile, on Macconkey media without cefotaxime, 79.9% were obtained. Based on macroscopic, microscopic, and biochemical characteristics, it was found that the gram-negative bacteria obtained were Escherichia coli. In sensitivity tests, it was found that the bacteria were resistant to tetracycline (100%) and ampicillin (100%), and 25% were resistant to chloramphenicol. The conclusion is that gram-negative bacteria found in the cecum of broiler chickens, such as Escherichia coli, are resistant to several antibiotics. These bacteria are resistant to cefotaxime (20.1%), chloramphenicol (25%), tetracycline (100%), and ampicillin (100%).
The Effect of Vitamin C Addition on the Antibacterial Activity of Pseudomonas aeruginosa in the Ethyl Acetate Fraction of Green Tea Leaves Rayes, Norina Shaumy Putri; Permatasai, Lina; Mukhlshah, Neneng Rachmalia Izzatul; Octora, Metta; Arnawati, Ida Ayu; Jannah, Fathul
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.9657

Abstract

Pseudomonas aeruginosais a major antibiotic-resistant pathogen frequently associated with hospital-acquired infections posing significant treatment challenges. This study aimed to evaluate the antibacterial activity of the ethyl acetate fraction of green tea (Camellia sinensis L.) enriched with vitamin C against Pseudomonas aeruginosa. The ethyl acetate fraction obtained from 96% ethanol maceration was tested at concentrations of 12,5-200 mg/mL both with and without vitamin C using the disk diffusion method and compared to aztreonam as a positive control. Results showed that vitamin C enrichment increased the inhibition zone from 12,5 mm to 13,8 mm at 200 mg/mL, while aztreonam produced the largest inhibition zone at 20,17 mm. The vitamin C-enriched formulation also maintened antibacterical activity more effectively over a 5-15 day storage period. Vitamin C is believed to stabilize the primary antimicrobial compound epigallocatechin gallate (EGCG) by preventing its oxidation. These findings support the potential of vitamin C-enriched green tea extract as an adjunctive therapy against Pseudomonas aeruginosa infections. Further development of topical or systemic formulations is recommended for managing resistant bacterial infections.
Phytochemical Screening of Purple Leaf Twig Extract Alfiyandhini, Elya Nanda; Sunarwidhi, Anggit Listyacahyani; Octora, Metta; Mukhlisah, Neneng Rachmalia Izzatul
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.6948

Abstract

Purple leaf (Graptophyllum pictum L. Griff) is a plant that has antibacterial, antioxidant, anti-inflammatory and antidiarrheal benefits. Flavonoids, alkaloids, steroids, saponins, and tannins are some of the secondary metabolites found in the leaves that have antibacterial properties. This study aims to determine the content of phytochemical compounds in purple leaf twig extract. The method used is phytochemical screening to identify flavonoid, alkaloid, saponin, tannin, steroid and terpenoid compounds. The results of phytochemical screening showed that the purple leaf twig extract contained flavonoid, saponin and terpenoid compounds. However, it did not show any steroid compounds. The conclusion is that the identification of secondary metabolite compounds in purple leaf twig extract contains flavonoid, saponin and terpenoid compounds. In contrast to the content of secondary metabolite compounds in G. pictum twigs is different from that in its leaves. 
Potential of Curcumin in Curcuma Longa as an Alternative Therapy for PCOS: A Literature Review Ishlahi, Salsabila Dinda Nuril; Octora, Metta
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7481

Abstract

Polycystic ovary syndrome (PCOS) is a common reproductive endocrine hormone disorder in women of childbearing age with a global incidence of 8-13%. The use of medical drugs in the long term can cause serious side effects so that the utilization of curcumin contained in Curcuma longa can be an alternative therapy consideration for PCOS. This paper will discuss the potential and benefits of curcumin content as an alternative therapy for PCOS. The method used, namely by reviewing the literature in national and international journals that are in accordance with the objectives of the review. The results of the literature review show that curcumin has effectiveness in treating PCOS through various mechanisms of action accompanied by minimal side effects. Alternative therapy of PCOS by taking curcumin needs to consider the dose, duration of use, and further research with larger subjects in assessing its effectiveness and side effects. However, it is suspected that nanocurcumin formulations have higher bioavailability and solubility than free curcumin, giving it even greater potential in the treatment of PCOS in the future. In conclusion, curcumin has the potential as an alternative therapy for PCOS that requires further research to achieve the optimization of PCOS treatment in the future.
Co-Authors Abdiman, I Made Tobias Alfiyandhini, Elya Nanda Amanullah, Mohammad Sany Rosafi Anak Agung Ayu Niti Wedayani Ardiana Ekawanti Arhya Putra, Made Raditya Ario Danianto, Ario Arnawati, Ida Ayu Azizatul Adni Barirah, Ratih Dedianto Hidajat Dian Puspita Sari Farras, Afif Fathul Jannah, Fathul Ginuluh, Gintis Dhimar Hardyningrat, Baiq Inna Dwi Hasbi, Nurmi - Hayaza, Safira Said Hazaa, Saskia Safarinaa Ika Primayanti Indratama, I Nyoman Yudayana Intan Wahyu Lasiaprillianty, Intan Wahyu Ishlahi, Salsabila Dinda Nuril Kadarisma, Shofia Kirana, Devi Chandra Makbul, Ini Hidayat Mujahid, Sabila Izzatina Azmy Mukhlisah, Neneng Rachmalia Izzatul Mukhlshah, Neneng Rachmalia Izzatul Nugraha, Kadek Nandita Permatasai, Lina Prihatina, Lale Maulin Putra, Yusril Sani Riandika Putri, Atina Rizki Rayes, Norina Shaumy Putri Retnaningsih, Ekawaty Rika Hastuti Setyorini, Rika Hastuti Rizqullah, Rifqi Rosyunita, Rosyunita Sholihatin, Illiyani Siti Nurhaliza Sunarwidhi, Anggit Listyacahyani Syari, Mayuarsih Kartika Teguh Budi Wicaksono Wangiyana, Ni Komang Ayu Swanitri Wilmayani, Ni Ketut Yahya, Najla Aulia