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All Journal BALI MEDICAL JOURNAL (BMJ) Jurnal Pendidikan dan Pembelajaran Khatulistiwa (JPPK) Jurnal Kesehatan Olahraga Majalah Kedokteran Bandung MNJ (Malang Neurology Journal) Syntax Literate: Jurnal Ilmiah Indonesia Pendas : Jurnah Ilmiah Pendidikan Dasar INTECOMS: Journal of Information Technology and Computer Science Biomolecular and Health Science Journal Community Development Journal: Jurnal Pengabdian Masyarakat CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) AGRONISMA International Journal of Advanced Multidisciplinary International Journal of Health Science and Technology Jurnal Ilmiah Agroust
Hermawan Susanto
Division Of Endocrinology, Diabetes, And Metabolism, Department Of Internal Medicine, Faculty Of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
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The Use of Oral Antidiabetic Drugs in Type-2 Diabetes Mellitus Patients with Macrovascular and Microvascular Complications at an Indonesian Tertiary Hospital, July-September 2023 Soesanta, Rasagama Putra; Purwaningsih, Sri; Susanto, Hermawan; Bodova, Klára
Current Internal Medicine Research and Practice Surabaya Journal Vol. 7 No. 1 (2026): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

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Abstract

Introduction: The incidence of Type 2 Diabetes Mellitus (T2DM) in Indonesia remains high and can lead to both macrovascular and microvascular complications, making research on the use of T2DM medications and their complications an important area of study. This study examines the use of oral antidiabetic drugs in T2DM patients with macrovascular and microvascular complications at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Methods: A descriptive, retrospective study was conducted using total sampling of medical records with the inclusion criteria of this study being 162 patients who were treated in the Internal Medicine Outpatient at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, for the period of July–September 2023 with the diagnosis code ICD-10 E11 and were treated with oral antidiabetic drugs. The exclusion criteria of this study were patients who are using insulin as their primary therapy. Results: Out of 162 patients, the demographic distribution showed that most patients were female (51.23%), with the highest age group being 55-64 years (41.35%). Body Mass Index (BMI) was mostly in the 18.5-22.9 and 23-24.9 ranges (33.95%), and the majority had been living with DM for 6-10 years (44.44%). Monotherapy, primarily metformin, was commonly used across all microvascular (retinopathy, nephropathy, neuropathy) and macrovascular (stroke, coronary heart disease (CHD), peripheral artery disease (PAD)) complications. The most frequently used combination therapy was metformin + glimepiride. Conclusion: The use of metformin as monotherapy and the combination of metformin and glimepiride were the most commonly used treatments for T2DM patients with complications.
Co-Authors Abdillah, Gipari Pradina Abdul Jabarsyah, Abdul Abdullah, Rizqy Achmad Firdaus Sani, Achmad Firdaus Achyani, Ratno Adnan, Kemal Agustini, Lukisiari Ahmad Yani T Archangela Olivia Eugenia Ardhi, Mohammad Saiful Arpinda, Arpinda Asbar Laga, Asbar Atsari, Nadhila Azwin Mengindra Putera Baehaqi Bodová, Klára Dadang Iskandar Mulyana` Dhimas Wiharyanto Djoko Heru Pamungkas Djoko Heru Pamungkas Dori Rachmawani Elfaretta, Zerlina Wina Fahrin Ramadan Andiwijaya, Fahrin Ramadan Febriana, Dian Tri Fundhy Sinar Ikrar Prihatanto, Fundhy Sinar Ikrar Gazali Salim Hafidhatul Aisy Haryono, M Gandri Heni Irawati Herin Mawarti Jongky Hendro Prajitno Kase, Ardy Andreas Bernard Lutfi, Delfitri Lutfiyah, Zahirah Siti Mahayu Woro Lestari Mansur Jauhari Muhammad Firdaus Muhammad Roem Muhtar, Dian Islamia Nasrudin Notonegoro, Danendra Satriyohadi Novi Arfarita Nur Rochmah Perdana, Philips Carel Raden Argarini Ramdan Pelana Rasiban Rian Arya Wijaya, Melik Budiarti Rokhim, Ahmad Romdoni, Taufiq Ahmad Setyawan, Adhitya Chandra Soesanta, Rasagama Putra Sri Purwaningsih Sugiatno Sugiatno Sunreza Millenia, Maasa SUTJIPTO Syamsidar Gaffar Taqwa, Amrullah Tuty Alawiyah Umyati, Sri Yuliawati, Tri Hartini Yushra, Yushra Yusuf, Muhammad Yusfi Zamroni Zamroni Zamroni Zamroni Zunianto, Anang