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All Journal Farmaka Biology, Medicine, & Natural Product Chemistry Majalah Obat Tradisional The Indonesian Biomedical Journal Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Jurnal Penelitian Farmasi Indonesia SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan JOPS (Journal Of Pharmacy and Science) JISIP: Jurnal Ilmu Sosial dan Pendidikan Jurnal Ilmu Kefarmasian Indonesia Jurnal Riset Kefarmasian Indonesia JPK: Jurnal Proteksi Kesehatan Jurnal Kolaboratif Sains Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Masyarakat Medika Journal of Artificial Intelligence and Digital Business Sinteza Jurnal Farmasi Indonesia Jurnal Pengabdian Masyarakat Borneo Journal of Pharmacy Jurnal Medika: Medika Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Meiriza Djohari, Meiriza
Sekolah Tinggi Ilmu Farmasi Riau
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Uji Validasi Metode Penetapan Kadar Ibuprofen dalam Sediaan Tablet dengan Nama Dagang dan Generik Secara Spektrofotometri UV Wirda Tulljannah; Rahma Dona; Tilar Eka Widia Ningrum; Meiriza Djohari
JURNAL FARMASI DAN MAKANAN Vol 8 No 1 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v8i1.5247

Abstract

This study aims to determine the levels of ibuprofen in tablet preparations using the UV spectrophotometric method and determine the suitability of ibuprofen tablets with trade and generic names that meet the requirements according to the Indonesian Pharmacopoeia Edition VI. The determination of ibuprofen levels in tablet preparations was tested for validity based on linearity, limit of detection (LOD) and limit of quantitation (LOQ) parameters, accuracy with the spiked-placebo recovery method and precision. Based on the results obtained linearity value of r = 0.9993 with limit of detection (LOD) 0.2825 ppm and limit of quantitation (LOQ) 0.9418 ppm, accuracy obtained at 3 concentrations of 8, 10 and 12 ppm respectively 99.59%; 99.29%; and 99.99% and on precision obtained RSD results of 0.77%; 0.49%; 1.48%. The results of the determination of levels in the four samples of generic tablet preparations and trade names are 100.91%; 104.02%; 100.91%; and 100.99%. From the results of the study, it is concluded that the UV spectrophotometric method used has met the parameters set in the validation test and the ibuprofen levels obtained also meet the requirements set in the Indonesian Pharmacopoeia VI Edition, which is not less than 90% and not more than 110%.
PENGARUH PEMBERIAN FRAKSI ETIL ASETAT DAUN TUMBUHAN AKAR KAIK-KAIK (Uncaria cordata (Lour.) Merr.) TERHADAP KADAR Low Density Lipoprotein (LDL) TIKUS PUTIH (Rattus novergicus) JANTAN: The Effect of Giving Ethyl Acetate Fraction of Leaves from Uncaria cordata on Levels of LDL of Male White Rats Meiriza Djohari; Fina Aryani; Haniyah Nabilah
JURNAL FARMASI DAN MAKANAN Vol 8 No 2 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v8i2.6222

Abstract

Akar Kaik-kaik (Uncaria cordata (Lour.) Merr) can be used as herbal medicine to decrease LDL level in the body. This research aims to determine the effect of ethyl acetate fraction the leaf of akar kaik-kaik (Uncaria cordata (Lour.) Merr) toward LDL level in a male white rat serum (Rattus norvegicus). The measurement method used is Direct Homogeneous Assay using reagents and photometer (Mindray® BA-88A) at a wave length of 578 nm. The results obtained in the form of LDL levels and analyzed using two-way ANOVA. The results showed that the ethyl acetate fraction in the leaves of akar kaik-kaik (Uncaria cordata (Lour.) Merr.) doses of 200 and 400 mg/KgBW kgBW could reduce LDL levels as seen from the significant difference (p<0.05) with the negative control group. and has a comparable effectiveness with atorvastatin seen from the absence of significant differences (p>0.05) with the positive control group.
PENGARUH PEMBERIAN JERUK NIPIS (CITRUS AURANTIFOLIA (Chrism.) SWING) TERHADAP KADAR TRIGLISERIDA DAN BERAT BADAN TIKUS PUTIH (RATTUS NORVEGICUS) JANTAN GALUR WISTAR Meiriza Djohari; Yuni Rahmi
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 4 No. 1 (2017)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v4i1.152

Abstract

The research about the effect of lime (Citrus aurantifolia (chrism.) Swing) to levels of triglycerides and body weight of male rats (Rattus norvegicus) wistar strain at a doses of 1.5, 3 and 4.5 ml/kg body weight has done. This study conducted on five groups consisted of norml control , negative control (-), dose of 1.5; 3 and 4 ml/kg body weight, each group consisted of 5 rats , The normal control group were given regular feed, control (-) was given 2 ml cow's brain and regular feed then the test group were given lime each with a dose of 1.5, 3 and 4.5 ml / kg body weight was added with 2 ml of cow's brain and regular feed. The method of measurement used is Enzymatic Colorimetric Test GPO (Glycerol-3-Phosphate Oxidase) at a wavelength of 546 nm. The results showed that administration of lime doses of 3 and 4.5 ml/kg body weight have a significant difference (p <0,05) to the control (-). However, at a dose of 4.5 ml/kg body weight more effectively and more quickly lowering triglyceride levels because the first measurement time of the second measurement time already showed a significant difference (p<0,05) .
Gambaran Penggunaan Multivitamin selama Pandemi COVID-19 di Apotek Kota Pekanbaru Fina Aryani; Windi Sayuti Ningsih; Meiriza Djohari; Anugrah Humairah
Sinteza Vol. 4 No. 1 (2024): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v4i1.21051

Abstract

Tingginya kasus COVID-19, mengharuskan masyarakat untuk melakukan berbagai upaya preventif atau pencegahan, salah satu upaya yang dapat dilakukan adalah dengan menjaga imunitas tubuh yang dapat ditingkatkan dengan penggunaan multivitamin. Multivitamin mengandung beberapa vitamin dan mineral, kecukupan zat gizi terutama vitamin dan mineral sangat diperlukan dalam mempertahankan sistem kekebalan tubuh yang optimal. Penelitian ini bertujuan untuk mengetahui penggunaan multivitamin pada masyarakat di salah satu apotek Kota Pekanbaru selama pandemi COVID-19. Penelitian ini merupakan penelitian observasional yang bersifat deskriptif dengan teknik pengambilan data secara retrospektif. Populasi pada penelitian ini adalah data semua penjualan multivitamin selama pandemi Covid-19 dari bulan Maret 2020 hingga Juni 2021. Sampel adalah semua populasi sehingga teknik pengambilan sampel yang digunakan yaitu sampel jenuh. Data yang diambil adalah data sekunder berupa data penjualan multivitamin selama pandemi Covid-19 dari bulan Maret 2020 hingga Juni 2021. Hasil penelitian menunjukkan bahwa penjualan nama multivitamin yang paling banyak adalah Zegavit® sebanyak 10,41% dengan zat aktif Vitamin C sebesar 45,40%, bentuk sediaan multivitamin yang paling banyak terjual adalah tablet atau kaplet dengan persentase 68,16% dengan komposisi kombinasi sebesar 98,42%. Berdasarkan hasil penelitian disimpulkan multivitamin yang paling tinggi angka penjualannya yaitu multivitamin kombinasi dengan bentuk sediaan tablet.
Co-Authors Achdar, Ridza Fitria Adelina, Helmi Rahmah Adilla, Dea Adriani Susanty Adriani Susanty Afridho, Arif agistia, nesa Alifah Nurul Khusnah Amalia, Annisa Yuri Amrianis, Delfi Andi Wijaya Annisa Safitri Annisa, Refina Anugrah Humairah Apriella, Weri Armon Fernando Ayu Indah Lestari Afandi Azizah, Wahyu Belia Sonali Bendre Burhanuddin Bahar Cahyani, Astri Dea Adilla Deni Anggraini Devi Safitri DEWI FITRIANI Dewi, Irana Dinda Zulfi Rosadi Diova Yuswidia Putra Dwi Pratiwi Enda Mora Enda Mora Erin Katerina Ewika Pritiya Utami Fadhila, Metha Fadhila, Qonita Nur Fadila, Azhariah Farahdilla, Dinda Fatimah Nur Afnita Febry Azizah H Fina Aryani Fina Aryani, Fina Fitri Yolanda Pratiwi Geby Mardhotillah Haiyul Fadhli Haniyah Nabilah Hasanah, Mitha Hesti Rahmatia Humairah, Anugrah Husnawati Husnawati Husnawati Husnawati Ihsan Ikhtiarudin Ikhwani, Ulfha Irfan Sihombing Jasma Jasma Karismawati, Karismawati Kuang, Liau Che Larasati Dinda Meditha Linda, Rosa M. Almurdani Mansyur Arif Mansyur Arif Maqfiroh, Wirdarani Mardianti, Tengku Shella Maulin Rahmawati Melia Oktavia Melisa, Eva Melzi Octaviani Mira Febrina Musyirna Rahmah Nst Muti’ah, Try Hadirah Nabilah, Clara Neni Frimayanti Nofri Hendri Sandi Noveri Rahmawati Novia Risky Nur Novia Sinata Nur Indah Melati Nurhapipah, Nurhapipah Nurhasanah Nurhasanah Nursyah, Salsabila Putri Parina, Ana Bella Pratiwi, Erniza Putri, Atika Putri, Bayzola Ditya Putri, Sella Hilmalia Nur Al Putri, Widia Rahma Putri, Wulandari Yulia Rahma Dona Rahmatunnur, Siti Rahmi, Yuni Rifani, Mhd Rina Lestari Rizki, Rahmi Asrina Rodhia Ulfa Rovi Paramitha, Rovi Rustam, Muhanifa Safitri, Salsa Widya Septi Muharni Setyowati, Bonita Dwi Sinata, Novia Sinulingga, Yori Yunita Sisca, Sari Kurnia Sufi, Tengku Yuni Atika Sukma Sukma Sulastri Sumbarita, Silvia Suryani As&#039;ad Susanti, Adriani Syilfia Hasti T. Harpirabi Tami Tami Tania Tiara Efendi Tania, Berla Tilar Eka Widia Ningrum Tri Wahyuni Wildan Rasyid Winda Yusma Ameliah Windi Sayuti Ningsih Winekas, Bintang Bayu Wira Noviana, Wira Noviana Wirahma Indah Pratiwi Wirda Tulljannah Yuni Rahmi Yuni Rahmi Yuti, Denisyah Fitri Zamri, Wiedya Alfitrya