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All Journal MEDIA MEDIKA INDONESIANA Media Kesehatan Masyarakat Indonesia Nurse Media Journal of Nursing Jurnal Kedokteran Diponegoro Jurnal NERS Majalah Obstetri dan Ginekologi The Indonesian Biomedical Journal Biomedical Journal of Indonesia Universa Medicina SPEKTRA: Jurnal Kajian Pendidikan Sains Jurnal Penelitian Pendidikan IPA (JPPIPA) Belitung Nursing Journal IJEMS (Indonesian Journal of Environmental Management and Sustainability) Media Medika Muda Martabe : Jurnal Pengabdian Kepada Masyarakat Eksakta : Berkala Ilmiah Bidang MIPA Majalah Patologi Indonesia Jurnal Biomedika dan Kesehatan Jurnal Smart Keperawatan Bioscientia Medicina : Journal of Biomedicine and Translational Research Medica Hospitalia Diponegoro International Medical Journal (DIMJ) Jurnal Ekonomi Indonesia International Journal of Engineering, Science and Information Technology Bioscientia Medicina : Journal of Biomedicine and Translational Research Life Science Journal of Health and Nutrition Research Berita Kedokteran Masyarakat Jurnal CARING (Center of Research Publication in Midwifery and Nursing)
Awal Prasetyo
Departemen Patologi Anatomik Fakultas Kedokteran Universitas Diponegoro
Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation

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Biosmart and safe bus : new approach implementing epidemiologic triangle to reduce pathogen transmission on public transportation Mentari, Alfitra Akbar Bara Mentari; Antari, Arlita Leniseptaria; Saraswati, Indah; Firmanti, Stefani Candra; Subagio, Agus; Prasetyo, Awal; Taufiq, Heydar Ruffa; Rowi, Khasan; Gufron, Ahmad
BKM Public Health and Community Medicine The 12th UGM Public Health Symposium
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Indirect pathogen transmission is one of the factors that cause the transmission of infectious problems from human to human. Surface cabine bus is one of the places that probably can be an intermediary of indirect pathogen transmission. Biosmart and Safe Bus is the concept of implementing an epidemiologic triangle, one of the innovations in Biosmart and Safe Bus is implementing silver nanoparticles as a coating in the cabine to decrease the bacterial load on the surface. Objective: To determine the effectiveness of coating silver nanoparticles in decreasing the bacterial surface load on the Biosmart and Safe Bus concept. Methods: This research used a post-test-only design with a control group. The sampling technique in this research is using surface swab sampling with a total of 18 samples in each Biosmart and Safe Bus and conventional bus that turn to Jakarta and Batu from Semarang. The data were analyzed by using the Mann-Whitney test, the Kruskal-Wallis test, and pairwise comparison Kruskal-Wallis test. Results: The results showed a significant difference between bacterial surface load on Biosmart and Safe Bus and conventional bus (p = 0.015). Along with it, the implementation of coating silver nanoparticles has a considerable effect (cohen effect size = 1.0324) in decreasing the bacterial surface load on the cabin of Biosmart and Safe Bus. The use of silver nanoparticles as a coating on the surface of Biosmart and Safe Bus is effective in being a surface antibacterial agent. This is in line with another research conducted in the United Kingdom with the result that the use of Ag antimicrobial BioCote as coating can reduce 95% surface bacteria. Conclusion: This research proved that coating silver nanoparticles is effective in decreasing the bacterial surface load on Biosmart and Safe Bus compared to a conventional bus.
Platelet-Rich Plasma (PRP) Allogenic: A Potential Challenge for Decreasing Random Blood Glucose, Uric Acid, and Cholesterol Levels in A Preliminary Pre and Post Test Study on Adult Subjects Diah Hastuti; Awal Prasetyo; Anzhari, Della Hashfi; Resti Ariani; Mutia Syafira; Anna Kartika Yuli Astuti; Rina Puspita
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 27 No. 01 (2026): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol27-iss01/643

Abstract

Ideally, metabolic homeostasis is maintained through stable glucose regulation, balanced lipid metabolism, and effective uric acid clearance under conditions of minimal systemic inflammation. In real clinical conditions, aging and persistent low-grade inflammation frequently disrupt this balance, leading to hyperglycemia, dyslipidemia, and elevated uric acid levels. Current pharmacological management mainly emphasizes metabolic control and may not sufficiently address underlying tissue dysfunction or inflammatory processes. Platelet-rich plasma (PRP) is a blood-derived bioregenerative product containing growth factors with anti-inflammatory and regenerative properties, offering a potential supportive approach for metabolic regulation. Nevertheless, PRP administration has predominantly relied on invasive delivery methods. Nebulization provides a non-invasive pulmonary route that enables rapid systemic absorption, representing an alternative delivery strategy. Despite its potential advantages, clinical evidence regarding the metabolic effects of PRP delivered via nebulization remains limited, creating an urgent need for preliminary clinical evaluation. Therefore, this pre–post test study aimed to assess the effects of allogeneic PRP nebulization on random blood glucose, uric acid, and total cholesterol levels. Fourteen adult subjects received PRP nebulization for five consecutive days. The intervention resulted in a significant reduction in random blood glucose levels and mild decreasing trends in uric acid and total cholesterol without serious adverse events.
The Effects of Kretek Cigarettes and Ascorbic Acid-based Vape on IL-6, TNF-α Levels, and Pulmonary Histopathology: An Experimental Study on White Rats (Rattus novergicus) on Inflammatory Response and Pulmonary Histopathology Maftikhati, Dora; Prasetyo, Awal; Sadhana, Udadi; Istiadi, Hermawan
Diponegoro International Medical Journal Vol 6, No 2 (2025): December 2025
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v6i2.29825

Abstract

Background: Smoking habits remain difficult to break, with 991 million smokers worldwide in 2020. Many have switched to vaping, which is regarded as safer than clove cigarettes. Exposure to cigarette smoke can increase pro-inflammatory cytokines and damage lung tissue.Objective: This study compared the effects of kretek cigarette smoke and ascorbic acid-based vape smoke on inflammatory response and lung tissue in male white rats (Rattus norvegicus).Methods: Twenty-one 8-week-old rats were randomized into three groups: control, exposed to kretek cigarette smoke, and exposed to ascorbic acid-based vape. The kretek cigarette group was exposed to smoke from 3 cigarettes/day, while the vape group received 0.5 ml/day of vape smoke, for 12 weeks. Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α) levels were analyzed using ELISA. The perimeter length of the alveolus, the degree of alveolar wall damage, and the extent of inflammatory cell distribution were also examined. Statistical analyses were accomplished using the ANOVA One-Way test, chi square test, and Kruskal-Wallis test.Results: Cigarette exposure significantly increased IL-6 levels (control: 8.43 ± 0.88 pg/ml; kretek cigarette: 11.45 ± 1.17 pg/ml; ascorbic acid vape: 11.83 ± 1.56 pg/ml; p = 0.000), the degree of alveolar damage (mean rank control: 6.21; kretek cigarette: 14.17; ascorbic acid vape: 11.64; p = 0.001), and the extent of inflammatory cell distribution (mean rank control: 4.00; kretek cigarette: 15.25; ascorbic acid vape: 12.93; p = 0.012). TNF-α levels increased in the kretek cigarette group, while the alveolar perimeter length increased in the ascorbic acid vape group; however, neither parameter was statistically significant (p > 0.05).Conclusion: Both kretek cigarette smoke and ascorbic acid-based vape smoke induced pulmonary inflammation and structural changes, with significant effects observed in IL-6 levels and histopathological damage, but not in TNF-α levels or alveolar perimeter length. There is a need for better regulation and increased public awareness about the dangers of smoking.
The Development of Wellness Tourism in Curug Wadas Malang, Mangkang, Semarang Hendro Prabowo; Awal Prasetyo; Yovhandra Ockta
Jurnal Penelitian Pendidikan IPA Vol 10 No SpecialIssue (2024): Science Education, Ecotourism, Health Science
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10iSpecialIssue.9089

Abstract

The research aims to develop Curug Wadas Malang in Mangkang as a wellness tourism destination within Semarang City. Utilizing field research, the study involved direct observation and interaction with individuals in their natural environment, as outlined by Sugiyono (2018). Observations were conducted in the Curug Wadas Malang forest area, alongside interviews with forest rangers, local residents, and Indonesian Red Cross (PMI) officers. This dual approach of simultaneous observations and interviews facilitated comprehensive data collection.In addition to fieldwork, a thorough literature review was undertaken to explore existing health tourism examples that incorporate natural elements such as forests, rivers, and waterfalls. The data gathered from both the literature and field research were thematically analyzed following the methodology proposed by Braun, Clarke & Hayfield (2022). The analysis revealed four key themes: the potential for wellness tourism at Curug Wadas Malang, the advantages of integrating forest, river, and waterfall elements in wellness tourism, a case study of Hoshinoya Karuizawa in Japan, and another case study from Kaua'i in Hawaii.The findings indicate that Curug Wadas Malang possesses significant natural resources and social capital through Community-Based Disaster Preparedness (CBDP) initiatives led by local communities. Therefore, a community-based tourism approach is recommended. This strategy emphasizes involving local populations in planning and implementing health tourism initiatives, enhancing disaster preparedness efforts while promoting sustainable tourism that benefits the community economically and socially
EDUKASI TERAPI OSTEOARTRITIS BERBASIS PENDEKATAN BIOREGENERATIF PLATELET RICH PLASMA DAN NON-FARMAKOLOGIS PADA LANSIA Ariani, Resti; Prasetyo, Awal; Sartini, D Nina; Puspita, Rina; P Setyo, Hendro; Jannati, Lu’luil; R Al-Ghifary, Arif
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 9, No 4 (2026): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v9i4.%p

Abstract

Osteoartritis (OA) lutut merupakan penyakit muskuloskeletal degeneratif yang banyak dialami oleh lansia dan menjadi salah satu penyebab utama nyeri kronis serta disabilitas fungsional. Perkembangan pendekatan bioregeneratif, seperti platelet-rich plasma (PRP), menunjukkan potensi dalam memperbaiki lingkungan biologis sendi melalui modulasi inflamasi dan stimulasi proses regeneratif jaringan. Namun, efektivitas pendekatan bioregeneratif sangat dipengaruhi oleh kondisi biomekanik sendi dan perilaku aktivitas individu. Oleh karena itu, terapi non-farmakologis berperan penting sebagai fondasi dalam menciptakan lingkungan sendi yang mendukung proses bioregeneratif sekaligus mencegah disabilitas. Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan pengetahuan dan keterampilan lansia dalam menerapkan terapi osteoartritis berbasis pendekatan bioregeneratif (PRP) dan non-farmakologis sebagai upaya pencegahan disabilitas lutut. Kegiatan dilaksanakan melalui workshop edukatif dan interaktif yang meliputi edukasi osteoartritis, pengenalan konsep bioregeneratif PRP, pelatihan latihan fisik aman, demonstrasi teknik kompres panas dan dingin, serta edukasi modifikasi aktivitas sehari-hari. Evaluasi dilakukan menggunakan metode pre-test dan post-test, observasi keterampilan, serta kuesioner kepuasan. Hasil evaluasi menunjukkan peningkatan pengetahuan dan keterampilan peserta secara jelas setelah mengikuti kegiatan. Program ini berkontribusi dalam meningkatkan kemandirian lansia, menciptakan lingkungan sendi yang kondusif bagi proses bioregeneratif, serta menurunkan risiko disabilitas lutut akibat osteoartritis
Reconnecting with Nature in the Built Environment: The Roles of Biophilic and Biomimetic Urban Design Awal Prasetyo; Hendro Prabowo; Wahyu Prakosa; Destri Maya Rani
International Journal of Engineering, Science and Information Technology Vol 6, No 2 (2026)
Publisher : Malikussaleh University, Aceh, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52088/ijesty.v6i2.1790

Abstract

Integrating nature into urban design has become a crucial approach for creating healthy, sustainable, and livable cities. This paper explores the multidimensional benefits and distinct roles of two transformative frameworks: Biophilic Design and Biomimetics. While both are rooted in nature, they offer complementary pathways. Biophilic Design focuses on human well-being, systematically integrating natural elements, light, and materials into the built environment to strengthen the innate human-nature connection, thereby improving mental and physical health, reducing stress, and enhancing social cohesion. In contrast, Biomimetics is a technical approach that solves complex urban challenges by emulating nature's models, principles, and ecological systems. It leads to innovative, efficient, and sustainable solutions, such as bio-inspired ventilation systems and materials that enhance urban resilience. The paper argues that moving beyond superficial greening, the synergistic application of Biophilic (human-centered) and Biomimetic (performance-centered) strategies enables a fundamental transformation towards regenerative, resilient, and dignified human settlements capable of addressing the pressing challenges of global urbanization and climate change.
Pengaruh Intervensi Mindfulness Terhadap Intensitas Kecemasan pada Pasien Kanker Nasopharal dengan Radiasi Jumatul Laely, Anna; Prasetyo, Awal; Bagus Ropyanto, Chandra
Journal Center of Research Publication in Midwifery and Nursing Vol 1 No 2 (2017): Journal Center of Research Publication in Midwifery and Nursing
Publisher : STIKES Bina Usada Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36474/caring.v1i2.2

Abstract

Kecemasan yang terjadi pada pasien kanker nasofaring pada masa radioterapi terutama disebabkan karena efek dari radiasi tersebut. Kecemasan pada tahap pengobatan menjadi sangat penting untuk diatasi karena dapat menyebabkan komorbiditas, trauma psikologis dan peningkatan mortalitas. Mindfulness merupakan psikoterapi yang efektif digunakan untuk mengurangi kecemasan pada pasien. Penelitian ini bertujuan untuk mengetahui pengaruh intervensi mindfulness terhadap intensitas kecemasan pada pasien kanker nasofaring yang sedang menjalani pengobatan radiasi. Metode penelitian yang digunakan pada penelitian ini adalah quasy eksperiment pre-post control trial design. Tigapuluh tiga responden dipilh dengan consecutive sampling dan terbagi dalam dua kelompok yaitu kelompok perlakuan dan kelompok kontrol. Pengukuran intensitas kecemasan dilakukan sebelum dan sesudah diberikan mindfulness selama 6 sesi menggunakan instrument Hamilton rating scale for anxiety (HAM-A). Uji hipotesis dilakukan untuk melihat pengaruh mindfulness dengan membedakan hasil sebelum dan sesudah dilakukannya intervensi pada kedua kelompok. Hasil Penelitian menunjukkan terjadi penurunan rata-rata tingkat kecemasan pada kelompok perlakuan setelah diberikan intervensi mindfulness dibandingkan dengan kelompok kontrol. Terdapat perbedaan signifikan tingkat kecemasan sebelum dan sesudah dilakukan mindfulness pada kelompok perlakuan dengan nilai P =0,001 (P<0,005).
Co-Authors - Anggorowati Adhi Setradian Anto Maria Aditya Purnama Agus Subagio Ahmad Hamim Sadewa Albertus Ari Adrianto Alendra Chakramurty Alfin Ihza Trimahendra Amira Naufal Anisa Ell Raharyani Anna Jumatul Laely Anna Kartika Yuli Astuti Antari, Arlita Leniseptaria Anzhari, Della Hashfi Apriana, Ledisda Ariani, Resti Arthur Lelono Arum Kartikadewi Asri, Hairul Astika Widy Utomo Astuti, Meira Dewi Kusuma Bagus Ropyanto, Chandra Bambang Endro Putranto Bambang Hariwiyanto Cahyono Hadi Cahyono Hadi Chandra Bagus Ropyanto Dadi Hamdani Darryl Samuel Salim Destri Maya Rani Devia Eka Listiana, Devia Eka Dewi Kartikawati Paramita Diah Hastuti Dik Puspasari Dik Puspasari Dik Puspasari, Dik Djaswadi Dasuki Djaswadi Dasuki Em Sutrisna Eriawan Agung Nugroho Gufron, Ahmad Halim, Fenny Hendro Prabowo Hendro Prabowo Hermawan Istiadi Hermawan Istiadi Heru Suwardianto Hidayat Sulistyo Hidayat Sulistyo Ika Pawitra Miranti Ika Pawitra Miranti Indah Saraswati Indwiani Astuti Indwiani Astuti Jannati, Lu’luil Jeffrey Eka Wijaya Jessica Christanti Jumatul Laely, Anna K. Heri Nugroho HS, K. Heri Karlowee, Vega Kenty Wantri Anita, Kenty Wantri Khasan Rowi Kusmiyati Tjahjono Kusmiyati Tjahjono Lisyani Budipradigdo Maftikhati, Dora Meira Dewi Kusuma Astuti Mentari, Alfitra Akbar Bara Mentari Mochamad Ali Sobirin Mohammad Hakimi Muniroh, Muflihatul Mutia Syafira Muzakar Isa Nani Maharani Neni Susilaningsih Nur, Rizki Widya Nurhayadi, Tommy Nurjaya Adinugroho P Setyo, Hendro Puspita, Rina R Al-Ghifary, Arif Rahajeng, Herera Redyaksa Drestanta Ariandoko Reni Sulung Utami Resti Ariani Rina Puspita Sarinti Sarinti Sarinti, Sarinti Sartini, D Nina Selvia David Richard Siahaan, Johanna Soenarto Sastrowijoto Sony Noegroho Sri Jumini Stefani Candra Firmanti Su, Hansen Maikel Suhartini Ismail, Suhartini Taufiq R Nasihun Taufiq, Heydar Ruffa Tjahjono Tjahjono Tjahjono Tri Nur Kristina Udadi Sadhana Udadi Sadhana, Udadi Vega Karlowee Veni, Rizka Wahyu Haris Prabowo Wahyu Prakosa Wahyuningsih, Indah S Wiratno Wiratno Yovhandra Ockta Yuriz Bakhtiar Yusuf, Franky