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All Journal Pharmascience Jurnal Pengabdian UntukMu NegeRI SAINTIFIK@ : Jurnal Pendidikan MIPA As-syifaa Jurnal Farmasi MATAPPA: Jurnal Pengabdian Kepada Masyarakat Media Farmasi JURNAL PengaMAS Saintifik : Jurnal Matematika, Sains, dan Pembelajarannya Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat JURNAL ILMIAH KESEHATAN SANDI HUSADA Jurnal Abdi Insani Community Development Journal: Jurnal Pengabdian Masyarakat Lumbung Farmasi : Jurnal Ilmu Kefarmasian BERNAS: Jurnal Pengabdian Kepada Masyarakat Journal SAGO Gizi dan Kesehatan INDRA: Jurnal Pengabdian kepada Masyarakat Journal Of Khairun Community Services Kieraha Medical Journal Jurnal Riset Farmasi Science Education and Learning Journal Jurnal Endurance: Kajian Ilmiah Problema Kesehatan Agrikan: Jurnal Agribisnis Perikanan Journal of Biotechnology and Natural Science Jurnal Farmasi Indonesia Jurnal Pengabdian Harapan Ibu (JPHI) Journal of Pharmaceutical and Sciences. BARAKATI: Journal of Community Service ABDI UNISAP: Jurnal Pengabdian Kepada Masyarakat Pharmacon: Jurnal Farmasi Indonesia Jurnal Ilmiah Kesehatan Sandi Husada
Amran Nur
Farmasi, Fakultas Kedokteran, Universitas Kairun
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Procedure for Distribution Permits for Traditional Medicines Products for the Convenience of Traditional Medicine Micro Business and Traditional Medicine Small Business in North Maluku Mas'ud, Abdu; Nur, Amran; Rodianawati, Indah; Sundari, Sundari
Agrikan Jurnal Agribisnis Perikanan Vol. 17 No. 1 (2024): Agrikan: Jurnal Agribisnis Perikanan
Publisher : Fakultas Pertanian, Universitas Muhammadiyah Maluku Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52046/agrikan.v17i1.2321

Abstract

The increasing use of traditional medicinein the country has encouraged an increase in Micro and Small Enterprises(MSMEs)engaged in traditional medicine, including Micro Traditional Medicine Enterprises (UMOT) and Small Traditional Medicine Enterprises (UKOT) which have begun to emerge in society. Based on survey, there are 11 MSMEs that produce essential oils for traditional medicine and only 27,3% od MSMEs meet the Good Manufacturing Practices for Traditional Medicine (CPOTB) stage 1. One of the obligation that must be fulfilled by UMOT or UKOT in distributing the traditional medicine they produce is to have a distribution permit number for the medicine. In managing adistribution permit for traditional medicine, business actors must meet severat requirments and go through several stages explained in this article. It is estimated that business actors, both UMOT and UKOT, find it easier to manage a distribution permit for traditional medicine.
Assistance in Establishing Microenterprises for Traditional Medicine (UMOT) and Implementing The Certification Procedure for Good Manufacturing Practices for Conventional Medicines (CPOTB) in The Dasa Wisma, West Tanah Tinggi Village, Ternate City Amran Nur; Eri Marwati; Bambang Tjiroso; Ermalyanti Fiskia
ABDIMAS: Jurnal Pengabdian Masyarakat Vol. 8 No. 1 (2025): ABDIMAS UMTAS: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPM Universitas Muhammadiyah Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35568/abdimas.v8i1.5453

Abstract

The Moloku Kie Raha area in North Maluku is a remote region in the northern part of the Indonesian archipelago. It has great potential for natural resources, particularly in producing essential commodities such as cloves, nutmeg, and mace. However, a group of women from RW 4 Tanah Tinggi Barat Subdistrict needed to understand the procedures for establishing UMOT and implementing CPOTB and the necessary documentation. The goal of the community service was to assist the RW 4 Dasa Wisma Women group in Tanah Tinggi Barat Subdistrict to establish UMOT in Ternate City and fulfill the CPOTB requirements to obtain BPOM permission. The activities included socialization of UMOT establishment and CPOTB implementation, training in preparing CPOTB documents, assistance in CPOTB implementation and production layout, support with registration (e-Registration), product marketing, and overall activity evaluation. The community service, conducted with a community empowerment framework, proceeded smoothly. The implementing team assisted in establishing UMOT, training in preparing CPOTB documents, assisting in CPOTB implementation and production layouts, registration support, and creating social media and marketplace platforms. The team also assisted with production equipment to meet the required standards, facilitating the Dasa Wisma RW 04 Women's Group business in Tanah Tinggi Barat Sub-district. The service team addressed mothers' economic productivity issues, offering solutions to the Dasa Wisma RW 04 women's group. With the establishment of UMOT for essential oils production, the group can increase economic income through a cost-effective manufacturing process, ultimately boosting their profits.
The level of compliance of type II diabetes mellitus patients in controlling blood sugar Nabilla Suratman; Liasari Armijn; Amran Nur
Jurnal Ilmiah Kesehatan Sandi Husada Vol 12 No 2 (2023): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v12i2.1126

Abstract

Diabetes mellitus is a chronic disease in the form of a metabolic disorder characterised by increased blood sugar levels that exceed normal limits. The purpose of the study was to determine the characteristics of type DM patients based on their level of adherence to drug use. The study used analytical descriptive methods with a cross-sectional study approach. Research samples were determined using the accidental sampling method on subjects who encountered as many as 44 pieces that doctors have diagnosed in the Kalumata Health Centre work area and according to inclusion criteria. Variable measurement using the Morisky Medication Adherence Scale questionnaire and validity and reliability analysis using SPSS version 25. Further tests were performed using bivariate Pearson correlation analysis. The results of the statistical analysis obtained sig values. (2-tailed) between age and gender, BPJS users' compliance rates are 0.510, 0.109, and -0.192, respectively. This means that there is no correlation or relationship. The variables of education level and type of work are 0.005 and 0.014, which significantly influence the level of compliance. It can be concluded that the variables that substantially impact the level of adherence of type 2 DM patients are education level and type of work. It is essential to constantly monitor and evaluate the effectiveness of implementing these recommendations to ensure an increase in the compliance rate of type 2 DM patients.
Pengaruh Suhu Pengeringan terhadap Aktivitas Antioksidan Ekstrak Daun Ungu (Graptophyllum pictum L. Griff) Salsabillah, Chaerunnisa; Abdullah, Abulkhair; Nur, Amran
Jurnal Pharmascience Vol 12, No 1 (2025): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i1.21010

Abstract

Daun ungu (Graptophyllum pictum L. Griff) telah lama dimanfaatkan sebagai obat tradisional untuk mengatasi berbagai penyakit yang berhubungan dengan radikal bebas. Kandungan flavonoid, alkaloid, saponin, dan tanin dalam daun ungu berperan sebagai antioksidan alami yang dapat menangkal radikal bebas. Namun, proses pengeringan dalam ekstraksi tanaman obat dapat memengaruhi kandungan senyawa bioaktif dan aktivitas antioksidan yang dihasilkan. Penelitian ini bertujuan untuk mengetahui pengaruh suhu pengeringan terhadap aktivitas antioksidan ekstrak daun ungu dan menentukan suhu optimal yang dapat menghasilkan aktivitas antioksidan tertinggi. Penelitian ini menggunakan metode eksperimental dengan pendekatan laboratorium. Daun ungu dikeringkan pada berbagai suhu (30℃, 45℃, dan 60℃), lalu diekstraksi menggunakan etanol 96%. Pada ekstraknya dilakukan uji kadar air, skrining fitokimia, dan uji aktivitas antioksidan menggunakan metode DPPH. Hasil penelitian menunjukkan bahwa kadar air ekstrak daun ungu yang dikeringkan pada suhu 30℃, 45℃, dan 60℃ masing-masing 5,69%, 5,82%, dan 5,87%. Pengujian skrining fitokimia menunjukkan bahwa pada suhu 30℃ dan 40℃ masih ditemukan berbagai jenis senyawa metabolit sekunder, sedangkan pada suhu 60℃ hanya teridentifikasi satu senyawa metabolit sekunder. Nilai IC50 untuk masing-masing suhu pengeringan adalah 32,46 μg/mL, 72,46 μg/mL, dan 193046,68 μg/mL.
H. Aktivitas Antiinflamasi Daging Buah Pala (Myristica fragrans Houtt.) Pada Tikus Putih Yang Diinduksi Karageenan Nur, Amran; Fiskia, Ermalyanti; Rahman, Ismail
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 1 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (428.674 KB) | DOI: 10.35617/jfionline.v14i1.87

Abstract

Inflammation is a defence reaction of the body to eliminate factors that can damage and then rebuild the body's homeostasis. Synthetic anti-inflammatory drugs are known to cause many side effects. Therefore, the research for new drugs from nature is carried out, generally sourced from natural ingredients. One of the natural ingredients that has potential as an anti-inflammatory is nutmeg flesh (Myristica fragrans Houtt.). This study aimed to determine the anti-inflammatory activity of nutmeg flesh ethanol extract (EDBP) in carrageenan-induced paw edema models in Wistar albino rats. This study is an experimental study using 30 Wistar albino rats that were randomly divided into six treatment groups which included a negative control group (Sodium CMC), a positive control group (diclofenac sodium 0.9mg/200gBW of rats), and three levels of ethanol extract of nutmeg flesh: 2.5mg/200gBW, 5mg/200gBW and 7.5mg/200gBW administered orally. One hour after the treatment, the rats were injected with 0.1 ml Carrageenan 1% sub plantar. The edema volume was measured with a plethysmometer every 30 minutes for 3 hours. Anti-inflammatory activity was measured by comparing the percentage of inflammatory protection. The data were then analysed using one-way ANOVA to compare the anti-inflammatory activity between the treatment and the control groups. The results showed that EDBP 2.5mg, 5mg, and 7.5mg gave significantly different effects compared to the control group (p<0.05), where EDBP 7.5 mg showed the highest anti-inflammatory activity.
Efektivitas ekstrak daging buah pala (Myristica fragrans Houtt) terhadap histopatologi hati pada tikus hiperglikemia Amran Nur; Safitri Hasda Nur; Nur Asma S. Somadayo; Muhammad Fakhrur Rajih
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3B (2024): Nopember
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3B.1927

Abstract

Background: Hyperglycemia can occur due to insulin resistance, which affects the metabolism of lipids, carbohydrates, proteins, and fatty acids in the liver, which will ultimately cause cirrhosis, steatohepatitis, liver cancer, and other liver disorders.Objectives: To determine the effect of administering nutmeg pulp extract (Myristica fragrans H.) on the histopathological picture of the liver of hyperglycemic mice induced by high carbohydrate feed.Methods: The research was carried out using an experimental method using 25 white rats (Rattus norvegicus) of the Wistar strain, which were divided into five groups, K- (NaCMC 1%), K+ (Metformin), P1-P3 respectively Nutmeg extract 100mg/kgBW, 200mg/kgBB, 300mg/kgBB). The entire group was given high carbohydrate feed for 30 days, then extract and Metformin for seven days. On the 36th day, the liver was removed, and histopathology preparations were made. The main research outcome parameters include initial blood sugar levels before induction (T0), final day blood sugar levels (T30), blood sugar levels on days 1, 3, 5, and 7 after sample administration, liver weight, and liver severity score. The data obtained were analyzed using Oneway-Anova with a significance of 0.05, and LSD as a further testResults: The K+, P1, and P3 groups showed a significant reduction in sugar compared to the control group (p<0.05), but all groups did not show an improvement in liver histopathology with damage scores in the mild to severe damage category.Conclusion: Nutmeg pulp extract at doses of 100mg/kgBB, 200mg/kgBB, and 300mg/kgBB showed effectiveness in reducing blood sugar in hyperglycemic white mice but could not show optimal improvement in liver cell damage.Keywords:Diabetes mellitus, Histopatology, Liver, Myristica fragrans, Nutmeg Flesh.
Assistance in Establishing Microenterprises for Traditional Medicine (UMOT) and Implementing The Certification Procedure for Good Manufacturing Practices for Conventional Medicines (CPOTB) in The Dasa Wisma, West Tanah Tinggi Village, Ternate City Nur, Amran; Marwati, Eri; Tjiroso, Bambang; Fiskia, Ermalyanti
ABDIMAS: Jurnal Pengabdian Masyarakat Vol. 8 No. 1 (2025): ABDIMAS UMTAS: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPM Universitas Muhammadiyah Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35568/abdimas.v8i1.5453

Abstract

The Moloku Kie Raha area in North Maluku is a remote region in the northern part of the Indonesian archipelago. It has great potential for natural resources, particularly in producing essential commodities such as cloves, nutmeg, and mace. However, a group of women from RW 4 Tanah Tinggi Barat Subdistrict needed to understand the procedures for establishing UMOT and implementing CPOTB and the necessary documentation. The goal of the community service was to assist the RW 4 Dasa Wisma Women group in Tanah Tinggi Barat Subdistrict to establish UMOT in Ternate City and fulfill the CPOTB requirements to obtain BPOM permission. The activities included socialization of UMOT establishment and CPOTB implementation, training in preparing CPOTB documents, assistance in CPOTB implementation and production layout, support with registration (e-Registration), product marketing, and overall activity evaluation. The community service, conducted with a community empowerment framework, proceeded smoothly. The implementing team assisted in establishing UMOT, training in preparing CPOTB documents, assisting in CPOTB implementation and production layouts, registration support, and creating social media and marketplace platforms. The team also assisted with production equipment to meet the required standards, facilitating the Dasa Wisma RW 04 Women's Group business in Tanah Tinggi Barat Sub-district. The service team addressed mothers' economic productivity issues, offering solutions to the Dasa Wisma RW 04 women's group. With the establishment of UMOT for essential oils production, the group can increase economic income through a cost-effective manufacturing process, ultimately boosting their profits.
Antioxidant Activity Test of Langsat (Lansium domesticum) Bark Extract with DPPH Nur, Amran; Saleh, Rahmat Dian; Rahman, Ismail; Fiskia, Ermalyanti; Rahman, Safriani
SAINTIFIK@: Jurnal Pendidikan MIPA Vol 10, No 1 (2025): SAINTIFIK@: Jurnal Pendidikan MIPA EDISI MARET 2025
Publisher : Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/saintifik.v10i1.9831

Abstract

Background: The langsat plant is a traditional plant that has long been used as an alternative to treat various health problems. Langsat bark apparently has extraordinary benefits and is closely related to its ability to fight free radicals. The bad effects caused by free radicals on the body can be prevented by using a substance called an antioxidant. The benefits of antioxidants for the body include protecting body cells from damage caused by free radicals. Langsat bark has extraordinary benefits, one of which is that it contains compounds that are antioxidant, anti-inflammatory, anti-diabetic and anti-cancer. Where langsat bark is known to contain several secondary metabolites, namely alkaloids, flavonoids, saponins, tannins and triterpenoids. Objective: This study aims to determine the antioxidant activity of langsat (Lansium domesticum) bark extract. Method: Determination of antioxidant activity using the DPPH (2,2-diphenyl-1-picrihidrazyl) method. Results: The antioxidant value of vitamin C and langsat bark extract are included in the very strong antioxidant category because both have IC50 values 50 ppm. Where the IC50 value 50 ppm is classified as a very strong antioxidant. In testing vitamin C, an average IC50 value of 6,378 μg/mL was obtained, while for langsat bark extract an average IC50 value was 10,654 μg/mL.Conclusion: Langsat bark extract has an IC50 value of 10,654 μg/mL so it is categorized as a very strong antioxidant.
Pengaruh Ekstrak Etanol Daging Buah Pala (Myristica Fragrans Houtt) Pada Histopatologi Jantung Tikus Wistar Hiperglikemik Nur, Amran; Fiskia, Ermalyanti; Hi Yusuf, Muhammad Fakhrur Rajih; A. Disi, Muhammad Zulfian; Mursin, Nita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.517

Abstract

The heart is an organ significantly impacted by diabetes mellitus problems, as elevated free radical generation and oxidative stress from hyperglycemia activate the apoptosis and necrosis pathways in cardiac myocytes. This study aimed to ascertain the histological characteristics of the cardiac tissue in rats subjected to hyperglycemia following the administration of ethanol extract from nutmeg fruit flesh (Myristica fragrans Houtt). This study employed rice as a diabetes inducer in 25 rats, categorized into 5 treatment groups: group 1 received Na-CMC, group 2 received metformin, group 3 received a dosage of 100 mg/KgBW, group 4 received a dosage of 200 mg/KgBW, and group 5 received a dosage of 300 mg/KgBW. The detected data included alterations in body weight, blood glucose levels, organ mass, and cardiac histology. The data were evaluated employing the One-Way ANOVA test at a 95% confidence level (p<0.05). The findings indicated that all groups treated with nutmeg fruit flesh ethanol extract exhibited a substantial enhancement in the histopathology of rat hearts compared to the negative control group 0,03 (p<0.05). The administration of nutmeg fruit flesh extract can ameliorate histopathological damage to the hearts of hyperglycemic rats at doses of 100 mg/KgBW, 200 mg/KgBW, and 300 mg/KgBW, indicating that nutmeg fruit flesh may serve as a cardioprotective drug in diabetic subjects.
Pemberdayaan Masyarakat Kelurahan Loto Dengan Pembuatan Kapsul Keloro (Kombinasi Daun Kelor dan Bunga Telang Biru) Nur, Amran; Fiskia, Ermalyanti
BARAKTI: Journal of Community Service Vol. 4 No. 1 (2025): Agustus
Publisher : PT. Sangadji Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tanaman kelor (Moringa oleifera) dan telang biru (Clitoria ternatea) adalah salah satu jenis tanaman tropis yang mudah dibiakkan dan sangat tahan terhadap kekeringan. Mereka juga memiliki banyak manfaat, termasuk sumber vitamin dan antioksidan. Tujuan kegiatan ini adalah untuk memberikan informasi tentang berbagai manfaat yang dapat diperoleh dari tanaman kelor dan bunga telang biru, terutama yang berkaitan dengan kesehatan. Salah satu cara pemanfaatan adalah dengan membuat sediaan yang lebih praktis sehingga masyarakat dapat mengonsumsinya. Sediaan ini dapat berupa kapsul yang disebut Keloro Kombinasi Daun Kelor dan Bunga Telang Biru. Kegiatan ini dilakukan melalui pendekatan kelompok, yaitu dengan memberikan sosialisasi kepada kelompok masyarakat di kelurahan Loto, di mana dijelaskan manfaat utama Daun Kelor dan Bunga Telang Biru, dan kemudian ditunjukkan cara membuat kapsul. Kegiatan ini meningkatkan pengetahuan masyarakat Kelurahan Loto tentang manfaat Daun Kelor dan Bunga Telang Biru terutama bagi kesehatan. Mereka juga belajar bahwa sediaan kelor tidak hanya dapat dibuat dalam bentuk sayuran dan tanaman hisas, tetapi juga dapat dibuat dalam bentuk kapsul yang lebih praktis. Diharapkan hasil dari kegiatan ini akan memberi masyarakat kelurahan Loto informasi tentang cara mengolah daun kelor dan bunga telang biru menjadi sediaan yang jauh lebih efisien tanpa menghilangkan manfaat utama dari daun kelor dan bunga telang biru itu sendiri.
Co-Authors Abd Hakim Husen Abulkhair Abdullah Andi Sakurawati Andi Sitti Nur Afiah Andika Isranugraha Anggi Siti Komariyah Ardiansyah, Rafli ARI WAHYUDI Ari Wahyudi Arif Santosa Azzahra, Rufaidah Bambang Tjiroso Bambang Tjiroso Bambang Tjiroso Bambang Tjiroso Bambang Tjiroso, Bambang Cindhany Darmaria Faridha Utami Mala Cindhany Darmaria Faridhah Utami Mala Dedi Ma’ruf desi reski fajar Desi Reski Fajar Eri Marwati Ermalyanti Fiskia Fajar, Desi Reski Febrianty, Marisca Fera The Handayani, Sri Windi Hartina, Sitti Hasan, Marhaeni Hi Yusuf, Muhammad Fakhrur Rajih Ibrahim Rahmat Indah Rodianawati indah rodianawati Ira Widya Sari Ismail Rahman Isranugraha, Andika Jasmawati, Jasmawati Liasari Armijn Marhaeni Hasan Marhamah Marhamah Mas'ud, Abdu Muh Nasir Muhammad Fakhrur Rajih Muhammad Fakhrur Rajih Hi Yusuf Muhammad Zulfian A. Disi Mursin, Nita Musdalifah Musdalifah Nabilla Suratman Natsir Djide Nur Asma S. Somadayo P.H, Dian Pramana Peter Kabo Rachman, Eva Syariefah rahman, ismail Rahmat, Septian Dwi Rajih, Muhammad Fakhrur S. Somadayo, Nur Asma Sadik, Fahmi Safitri Hasda Nur Safriani Rahman, Safriani Sakti, Aditya Sindu Sakurawati, Andi Saleh, Rahmat Dian Salsabillah, Chaerunnisa Sandrawati, Sandrawati Soesanty Soesanty suhardi suhardi Sundari Sundari The, Fera TOKA, WAHYUNITA DO Veronica Margareth Dampung