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All Journal International Journal of Public Health Science (IJPHS) Jurnal Presipitasi : Media Komunikasi dan Pengembangan Teknik Lingkungan Media Kesehatan Masyarakat Indonesia Jurnal Kesehatan Lingkungan indonesia Jurnal Kesehatan Masyarakat VISIKES Jurnal Kesehatan Lingkungan LINK JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) Buletin Keslingmas Jurnal Manajemen Kesehatan Indonesia Jurnal Ilmiah Mahasiswa HIGEIA (Journal of Public Health Research and Development) Journal of Health Education HIGIENE: Jurnal Kesehatan Lingkungan Jurnal Penelitian Pendidikan IPA (JPPIPA) Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Serambi Engineering Jambura Journal of Health Sciences and Research Jurnal Riset Kesehatan Poltekkes Depkes Bandung Contagion: Scientific Periodical Journal of Public Health and Coastal Health Jurnal 'Aisyiyah Medika PREPOTIF : Jurnal Kesehatan Masyarakat An-Nadaa: Jurnal Kesehatan Masyarakat KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat Journal of Telenursing (JOTING) Jurnal Aisyah : Jurnal Ilmu Kesehatan Indonesian Journal of Global Health research JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH Mitra Raflesia (Journal of Health Science) Jurnal Ilmiah Wahana Pendidikan ENVIRONMENTAL OCCUPATIONAL HEALTH AND SAFETY JOURNAL Narra J Open Access Health Scientific Journal Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Jurnal Impresi Indonesia Journal of Social Research COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Sanitasi: Jurnal Kesehatan Lingkungan Jurnal Riset Kesehatan Masyarakat Berita Kedokteran Masyarakat Journal of Noncommunicable Diseases (JOND) Gema Lingkungan Kesehatan Journal of Pharmaceutical and Sciences. Malahayati International Journal of Nursing and Health Science
Mursid Raharjo
Bagian Kesehatan Lingkungan, Fakultas Kesehatan Masyarakat, Universitas Diponegoro
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health)

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Association Between Pesticide Exposure and Type 2 Diabetes Mellitus Among Female Farmers: A Cross-Sectional Study Masyithah, Wulan; Onny Setiani; Yusniar Hanani Darundiati; Mursid Raharjo; Nurjazuli
JURNAL KESEHATAN LINGKUNGAN Vol. 17 No. 3 (2025): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v17i3.2025.220-229

Abstract

Introduction: The widespread use of pesticides in agriculture has been linked to an increased risk of diabetes mellitus. Long-term exposure to pesticides can disrupt glucose metabolism, trigger insulin resistance, and raise susceptibility to diabetes mellitus. This study investigates the association between pesticide exposure and the incidence of type 2 diabetes mellitus. Methods: This analytical observational study with a cross-sectional design involved 162 female farmers selected by purposive sampling from a population of 2,187, using the Lemeshow formula. Independent variables included work duration, types and frequency of pesticide use, spraying duration and direction, PPE usage, and cholinesterase levels. The dependent variable was type 2 diabetes mellitus. Data were collected through questionnaires, observation, and clinical tests for blood glucose and cholinesterase levels. Logistic regression was performed at 95% CI and α = 0.05. Result and Discussion: The results showed that 69.1% of female farmers exposed to pesticides had diabetes with lower cholinesterase levels as a significant indicator (p<0.001; OR=3.897; 95% CI=2.087-7.277). Factors such as working duration ≥10 years (p=0.010; OR=3.564; 95% CI=1.359-9.346), number of pesticides types (p=0.023; OR=3.370; 95% CI=1.187-9.570), spraying duration (p=0.020; OR=3.083; 95% CI=1.197-7.940), and PPE usage (p=0.007; OR=3.601; 95% CI=1.416-9.159) were associated with type 2 diabetes mellitus. Conclusion: Pesticides, particularly organophosphates and carbamates, act as endocrine-disrupting chemicals that impair pancreatic function and increase oxidative stress, contributing to insulin resistance. Female farmers more vulnerable to these effects due to hormonal sensitivity, making gender specific approaches essential. Strict regulations and farmer education are crucial to reduce long-term health risks.
Subclinical Renal Dysfunction in Horticultural Farmers: Early Detection in High Pesticide Exposure Areas Hansen; Mursid Raharjo; Suhartono; Nur Endah Wahyuningsih
JURNAL KESEHATAN LINGKUNGAN Vol. 17 No. 4 (2025): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v17i4.2025.379-388

Abstract

Introduction: Globally, Chronic Kidney Disease of Unknown etiology (CKDu) poses a growing medical and social challenge, particularly in agrarian countries with a high prevalence of pesticide exposure. Indonesia, is one of the countries with a dominant agricultural sector. Tanjungsari and Glonggong villages in Wanasari subdistrict, Brebes Regency, are agricultural areas with a high intensity of pesticide use. Methods: This research aimed to identify the prevalence of subclinical renal dysfunction and associated risk factors in horticultural farmers in areas with high pesticide exposure. This research applied a cross-sectional method involving 40 farmers aged 26-65 years from two villages in Wanasari District, Brebes Regency. Data collection was carried out through interviews, and examination of kidney function biomarkers (serum creatinine and eGFR). Statistical analysis was conducted using Logistic Regression tests. Results and Discussion: The study revealed that 37.5% of participants exhibited eGFR values <90 ml/min/1.73 m2, indicating subclinical impairment of kidney function. Employment duration >20 years (p=0.024; OR=6.000; 95% CI:1.263-28.498) and daily working hours >6 hours (p<0.001; OR=69.279; 95% CI:6.423-756.965) showed a significant association with reduced eGFR values. Occupational health interventions should prioritize managing the duration and intensity of exposure to hazardous substances in the workplace, regardless of the workers' gender. Conclusion: The conclusion is that the daily working hours and the employment duration of the farmers are significantly associated with impaired kidney function, potentially acting as an initial marker of CKDu.
Co-Authors -, Fitni Hidayati AA Sudharmawan, AA Adilasari, Philomena Larasati Aditya, Vanessa Rizky Agus Subagio Aini Nurul Alfia Nugrahani Sidhi Amarullah, Novi Ana Fauziah Andika Agus Iryanto Annisa Zolanda Annisa Zolanda Antonius Tae Asa, Antonius Tae Apoina Kartini Aslina, Enna Astri Wulandari Atyaf Umi Faizah Bagoes Widjanarko Bahri Bahri Bahri Bahri Bahri Bahri Baji Subagyo Budi, Waella Septamari Budiyono Budiyono Budiyono Budiyono Charisna Neilal Muna Damayanti, Wida Ayulia Desy Mery Dorsanti Dewi, Candrawati Puspita Dinar Andaru Mukti Dorsanti, Desy Mery Dwi Fitriani Dwi Fitriani Dwi Sutiningsih Fachrizal Ganiwijaya Familiantoro, Familiantoro Farid Agushybana Farid Farid Agushybana Fauziah El Syani Fernando P, Nickolas Fitri, Clara Ghinaa Maniiah Hansen Hanung Nurany Hariyanti, Fika Harmendo Hartini Sulistyandari, Hartini Haryanti, Nelly Hasim, Jamal Hisham Hasrah Junaidi Helmin Rumbiak, Helmin Hendrika Puspita Sari, Hendrika Puspita Husni, Siti Hajar i Joko, Tr Intan Sekar Arumdani Irawati, Roosdiana Jamal Hisham Hashim Kartika Permatasari Khaira Ilma Lewinsca, Maurend Yayank Liena Sofiana martini Martini Martini Martini Martini Martini Martini2 Masyithah, Wulan Mateus Sakundarno Adi, Mateus Sakundarno Maulida Khairunnisa Maurend Yayank Lewinsca Maurend Yayank Lewinsca Mitha Karunia Baeti Mohammad Zen Rahfiludin Mutia Permata Iryanti Nadiva Dzikriyati Nadiva Dzikriyati Nickolas Fernando Parmualan Niki Astorina Yunita Dewanti Nikie Astorina Yunita Dewanti Nikie Astorina Yunita Dewanti Nilna Fasyya Salsabila Nopi Reknasari Nopi Reknasari Nor Aisyah Purnamasari Novia Luthviatin Nugraha, Ferry Satya Adi Nur Endah Wahyuningsih Nur Endah Wahyuningsih Nuraini Nuraini Nurdin Nurdin Nurdiyanto, Miftakhul Nurjazuli Nurjazuli Nurjazuli Nurjazuli Nurjazuli Nur’Aini Nur’Aini Onny Setiani Onny Setiani Pramudiyo Teguh Sucipto, Pramudiyo Teguh Pratiwi, Dian Eka Puguh Ika Listyorini Purnama, Wary Purnamasari, Nor Aisyah Raharjo, Puspito Rasyid, Khairul Restiana, Shafira Azura Retno Hestiningsih Richard Victor Ombuh Rosa Rantetoding, Rosa Saffira Kusuma Anggraeni Sakundarno Adi Sari Lestari Rahmawati Saudin Yuniarno Setiadi, Robby Setiani , Onny Sigit Tri Ambarwanto, Sigit Tri Solly Aryza Sri Mulyati Sri Poerwati1, Ari Probandari2, Joko Sutrisno3, Ari Handono Ramelan4 Sri Slamet Mulyati, Sri Slamet Suci Kurniawati Sugeng Juwono Mardihusodo Suhartono Suhartono Suhartono Suhartono, Suhartono Sujarwo Sujarwo Sularno, Suryo Sulistiyani Sulistiyani SULISTIYANI SULISTIYANI Sulistiyani Sulistiyani Sulistyani Sulistyani Sunindy Wahyunita Supri Ahmadi, Supri Sutikno Sutikno Sutrisno, Sutrisno Suwito Suwito Tampubolon, Sinthania Karunia Magdalena Tika, Vira Tri Joko Tri Joko Tri Joko Vijja Ratano Vira Tika Yuniar Waella Septamari Budi Wahyudi Wahyudi Watmanlusy, Efraim Wayangkau, Erich C. Wayangkau, Erich Christian Windy Cintya Dewi Windy Cintya Dewi Yana afrina Yundari, Yundari Yusniar Hanani Yusniar Hanani Yusniar Hanani Darundiati Yusniar Hanani Darundiati Yusran Fauzi Yusuf Afif Zahra, Nabilah