Claim Missing Document
Check
Articles

Pengaruh Pemberian Alkohol Peroral Terhadap Nilai Mean Corpuscular Volume, Morfologi Eritrosit Darah Tepi dan Normoblas Sumsum Tulang Rodhi Hartono; Soewono Soewono; Tri Ratnaningsih
Jaringan Laboratorium Medis Vol 1, No 1 (2019): May 2019
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v1i1.5161

Abstract

A true experimental research with pre-post test control group design was carried out using 36 adult experimental male rats (strain wistar Rattus norvegicus) ,aged 10 weeks with weight of 200-250 grams. Before being given the treatment, the rats blood were taken out around 1,5 cc to measure the MCV value and the erythrocyte morphology. The rats were divided into 6 groups. The first group was the control group and the other five were the treatment group which were treated with different concentration of alcohol continuously for 45 days. After being treated, the rats blood were taken as same as the investigator did previously to examine the MCV value and the erythrocyte morphology, included the removal of right femur to assess morphology and bone marrow normoblast diameter. Results of the study showed that  there was increasing  on  MCV value after the treatment that was proportional to the  alcohol  concentration given (p 0.0000.05), likewise the changing of erythrocyte morphology was in term of acanthocytes  target cells, and stomatocyt . However, these research findings showed that there were no significant different in each group resulting  of the treatment (p 0.817 0.05). Yet,there was an inclination of normoblast diameter. Finally, it can be concluded that consuming oral alcohol continuously increases the MCV value, changing of erythrocyte morphology and bone marrow normoblast.
The Effect of Bacille Calmette-Guerin (BCG) on the Changes in Number and Functional Activities of Mononuclear Phagocytes in Malaria- infected Mice Model Supargiyono -; Mahardika Agus Wijayanti; Tri Ratnaningsih; Dian Nugraheni
Tropical Medicine Journal Vol 1, No 1 (2011): Tropical Medicine Journal
Publisher : Pusat Kedokteran Tropis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/tmj.4569

Abstract

Introduction: Recent studies have indicated that Bacille Calmette-Guerin (BCG) vaccination may have benefi cial eff ect on the survival of infant living in malaria endemic area as well as of malaria-infected mice model. However, the impact of injection of BCG vaccine on the changes in number and functional activities of Mononuclear Phagocytes during malaria-infection in animal model is still poorly understood.Objectives: To evaluate the eff ect of BCG on the changes in number and functional activities of Mononuclear Phagocytes (MPs) during Plasmodium berghei infection.Methods: Two groups of 18 Swiss mice were used. The fi rst group was given 0.1 ml of BCG injection subcutaneously and the second was the control non-BCG group. One week after BCG injection, all mice in both groups were inoculated with 107 Plasmodium berghei infected erythrocytes. The parasitaemia were monitored daily and the number and functional activity of splenic and peritoneal macrophages were tested.Results: The parasites were detected in the blood of both groups on the fi rst day after infection. The parasitaemia in the control group grew slowly until day 3, followed by rapid increased up to 38.96% on day 9. Parasitemia of mouse which still alive on day 12 was 59.6%. The parasitaemia of BCG-injected mice were also increased at lower rate after day 3, and the mice still survive until day 15 after infection. The number of peritoneal macrophages from BCG-injected mice increased to a higher degree compared to the non-BCG injected mice. Moreover, the phagocytic activities of peritoneal macrophages in BCG injected group were increased higher up to twice (200%) of normal levels compared to the non-BCG control group which increase only up to 1,5 times (150%) of the normal levels.Conclusion: The injection of BCG on Plasmodium berghei infected Swiss mice resulted in the extension of survival of the mice until day 15, accompanied by higher increased in number of circulating blood, splenic and peritoneal MPs, and the phagocytic activities of peritoneal MPs up to 137% of the increased in non-BCG mice.Keywords: BCG vaccine, malaria, Plasmodium berghei, macrophages, phagocytosis.
The role of red blood cell indices to identify iron deficiency in anemic pulmonary tuberculosis patient Tri Ratnaningsih
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 40, No 01 (2008)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: iron deficiency anemia (IDA) is often associated with infectionlinflammation disease, such as pulmonary tuberculosis. The biochemical parameters tests of iron metabolism are expensive relatively and not always available in some health centers. Objective: The aim of this study was to know the role of red blood cell indices to identify iron deficiency on pulmonary tuberculosis patient with anemia using a sTfR-based biochemical classification of ACD and ACD with iron deficiency (COMB!). Methods: The patient population consisted of 68 consecutive anemic pulmonary tuberculosis patients at the Sardjito Hospital and Balai Pengobatan Penyakit Paru-Paru 0.1. Yogyakarta, Indonesia. Result: Of 68 subjects, 53 had anemia of chronic disease (ACD) and 15 had iron deficiency anemia (COMBI). It was founded a significant difference between ACD group and COMBI group. There were significant correlations between red blood cell indices and sTfR. The most valid parameter to diagnose 10 is MCHC < 31.55 g/dL (Sn= 67%, Sp= 75%), followed by MCV < 81.65 fL (Sn= 62%, Sp= 73%), MCH < 25.75 pg (Sn= 67%, Sp= 70%), and lastly ROW> 14.95 (Sn= 73%, 57%). The diagnostic performances of this parameter at levels commonly used: MCV < 76 fL (Sn= 13%, Sp= 85%), MCH < 27 pg (Sn= 100%, Sp= 45%), MCHC < 31g/dL (Sn= 13%, Sp= 85%), and RDW > 15 (Sn= 67%, 60%). Conclusion: The usage of red blood cell indices can help us to identify iron deficiency in anemic pulmonary tuberculosis patients. For practical reason, more convenience if we use the value that is widely accepted. However, the red blood cell indices cannot be used solely, but must be combined for a greater accuracy.
RELATIONSHIP OF PARENTING TO PERSONAL HYGIENE INDEPENDENT OF PRE SCHOOL IN DHARMA WANITA KINDERGARTEN, JATIREJO MOJOKERTO Tria Wahyu Ningrum; Tri Ratnaningsih; Siti Mas Miranda
INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) Vol 1 No 2 (2017): IJNMS Volume 1 Issue 2, Desember 2017
Publisher : Bina Sehat Press. Departement Research and Community Engagement Bina Sehat PPNI Institute of Health Science, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.272 KB) | DOI: 10.29082/IJNMS/2017/Vol1/Iss2/70

Abstract

Currently, many children of school age are lacking in hygiene themselves so as to facilitate the occurrence of diseases such as diarrhea or intestinal worms. This situation occurs because the child is not yet able to perform personal hygiene independently or still assisted by parents. The purpose of the research to know the relationship of parenting pattern with preschool children hygiene personal independent. Design of this research was analytic correlational with crossectional approach. Research variables were parenting pattern as the independent variable and independent personal hygiene as the dependent variable. Population research was all of the parents who have children in kindergarten preschool age of Dharma Wanita Jatirejo Mojokerto. Samples were taken with the technique of total sampling as much as 45 respondents. Data collected by questionnaire sheet and tested with a test of chi-square. The results showed that respondents from 16 to apply democratic parenting most of self-reliance, personal hygiene of children in independent category as much as 9 respondents (20.0%), of the 16 respondents who applied the authoritarian parenting there are no independent and children from parents who apply the permissive parenting most of the children belonged to independent as much as 5 respondents (11.1%). The chi-square test results obtained the value of ρ = 0, 006 and α = 0.05 so ρ α there is relationship < parenting parents against independent, personal hygiene for children. This shows the more appropriate parenting adopted parents will further improve the independent of the personal hygiene of preschool age children. Give a freedom to children do make children become easy to do some useful thingParenting adopted by parents in educating children will give impact on the child's independent and personality s for her future, but in the absence of parental control, in fact, will make children become unruly. Key Words : Parenting, Personal Hygiene Independent, Preschool Children
KESAHIHAN DIAGNOSTIK HEMOGLOBIN RETIKULOSIT UNTUK DETEKSI DEFISIENSI ZAT BESI DI KEHAMILAN (Diagnostic Validity of Reticulocyte Hemoglobin for Iron Deficiency Detection in Pregnancy) Tri Ratnaningsih; Budi Mulyono; Sutaryo Sutaryo; Iwan Dwiprahasto
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 21, No 3 (2015)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v21i3.1282

Abstract

Entering the second trimester of pregnancy, more iron is required due to the increase in erythrocyte mass, plasma volume andthe development of fetus as well as chorion. Iron is needed the most in the third trimester. The existing hematological iron stageparameters can only detect iron deficiency in the latest stage. The aim of this study was to know the assessment validity of Ret-Heexamination as a new parameter to diagnose iron deficiency in pregnant women with anemia, as well as a screening tool for those interm pregnancy without anemia. The research design was cross sectional. The subjects were women in term pregnancy, gathered fromPKU Muhammadiyah Hospital, Bantul Yogyakarta from May to November 2013. A seven (7) mL blood sample was taken from thecubital vein of the subjects. Two mL of the sample was tested for routine hematological examination using an EDTA tube, while theRet-He was assessed using an automatic hematological instrument Sysmex XT-2000-i (Symex Corporation, Kobe, Japan). The serumof the remaining five (5) mL was used to check the serum iron and TIBC to obtain the saturation value (Tsat) using Cobas analyzerC501 (Roche Diagnostics, Germany), while the serum ferritin (SF) was examined using Minividas. The subjects were classified into two(2) groups based on the Hb levels, namely: anemia (Hb<11 g/dL) and those who did not (Hb≥11 g/dL). Furthermore, they were alsoclassified into two (2) groups based on transferrin saturation values: iron deficient (Tsat <9%) and normal (Tsat ≥9%). From 291subjects, 59 (20.3%) were found to have anemia and 232 (79.7%) did not. The cut off value of Ret-He to diagnose iron deficiency inpregnant women with anemia was 29.8 pg (82% sensitivity and 72% specificity). Meanwhile, the cut-off value of Ret-He for irondeficiency screening in pregnant women without anemia was 29.8 pg, with a sensitivity and specificity of 92% and 87% respectively.The Ret-He holds a good diagnostic validity to detect iron deficiency in pregnancy, with or without anemia.
IMPLEMENTASI MASK-RCNN PADA DATASET KECIL CITRA SEL DARAH MERAH BERDASARKAN KRITERIA WARNA SEL Dyah Aruming Tyas; Tri Ratnaningsih
Rabit : Jurnal Teknologi dan Sistem Informasi Univrab Vol 8 No 1 (2023): Januari
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/rabit.v8i1.3026

Abstract

Pemeriksaan morfologi sel darah merah merupakan salah satu alat bantu penegakan diagnosis pada beberapa penyakit, salah satunya anemia. Perkembangan penerapan teknologi pengolahan citra digital, kecerdasan artifisial dan computer-aided diagnosis membuka peluang untuk menyelesaikan berbagai permasalahan terkait citra medis. Sel darah merah yang saling menempel atau bertumpuk merupakan tantangan dalam proses segmentasi sel darah merah yang pada akhirnya berpengaruh pada hasil pengenalan jenis sel. Metode yang dapat melakukan instance segmentation sangat diperlukan untuk mengatasi masalah tersebut. Penelitian ini bertujuan untuk mengimplementasikan algoritma Mask-RCNN pada dataset kecil citra sel darah merah dan mengevaluasi performa hasil prediksi. Berdasarkan hasil penelitian sel-sel darah merah yang menempel dapat dideteksi secara individual oleh model dan akurasi hasil deteksi sel adalah 68,27%. Mask-RCNN dapat digunakan untuk instance segmentasi sel darah dan deteksi sel darah pada dataset kecil namun akurasi model masih perlu ditingkatkan. oleh sebab itu perlu dilakukan penelitian selanjutnya dengan menambah jumlah dataset yang digunakan.
Nutritional status, anemia status and application of the Mentzer index on complete blood examination results of students Pratama, Yanasta Yudo; Ratnaningsih, Tri; Arijadi, Desi; Adnan, Muhammad Luthfi; Widyasari, Vita; Tristifany, Annisa; Santoso, Griselda Elisse; Usman, Muhammad Alvin Ramadhan; Miftahurrahmi, Rofifah
JHeS (Journal of Health Studies) Vol. 7 No. 2 (2023): September
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.3199

Abstract

Thalassemia is a disease that attacks the hemoglobin gene, causing disturbances in erythropoiesis. Anemia is a condition in which the hemoglobin (Hb) concentration and the number of erythrocytes are below normal limits. The high number of anemia and thalassemia causes the need for early detection in order to prevent adverse effects in the future. Research objectives: to determine nutritional status, anemia status, and application of the Mentzer Index for SMK Muhammadiyah II Moyudan students. Methods: This study is a descriptive study with a cross-sectional design. The research subjects were first graders at SMK Muhammadiyah 2 Moyudan. Venous blood samples were examined at the Clinical Pathology Laboratory of FK-KMK UGM using the Sysmex XN-1000 tool on November 25, 2021. Data analysis used IBM SPSS Version 26 and Microsoft Office 365. Results: A total of 53 subjects participated in this study. A total of 47 (89%) respondents had normal hemoglobin values, and 6 (11%) respondents suffered from anemia. 31 (58.5%) respondents have normal nutrition, 15 (28%) respondents have less nutrition, 7 (13%) have excess nutrition, and 29 (54.7%) respondents have normal status. A total of 2 (3.8%) respondents showed Thalassemia. Conclusion: There are two students of SMK Muhammadiyah 2 Moyudan diagnosed with thalassemia and five students diagnosed with anemia. No statistically significant difference exists between Anemia Status in Adolescents at SMK Muhammadiyah 2 Moyudan and Nutritional Status. Further study is needed in wider and more diverse populations to analyze the influence of nutritional conditions on anemia in adolescents.
The Role of Neutrophil to Lymphocyte Ratio (NLR) and Platelet to Lymphocyte Ratio (PLR) in Appendicitis Heriyanto, Moch Junaidy; Ratnaningsih, Tri; Heriyanto Putri, Rona Hafida; Fatimah, Bunga; Astuti, Fardhiasih Dwi
JBN (Jurnal Bedah Nasional) Vol 8 No 1 (2024): JBN (Jurnal Bedah Nasional)
Publisher : Program Studi Ilmu Bedah, Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JBN.2024.v08.i01.p01

Abstract

Aim: Predictive values of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are associated with poor outcomes in several diseases. Furthermore, there has been limited publication of those parameters in appendicitis patients in Indonesia. This study aims to evaluate the role of NLR and PLR in differentiating complicated appendicitis and uncomplicated appendicitis. Methods: The design of this study is a retrospective using medical records of appendicitis patients from January 1, 2016, to December 31, 2020, conducted at PKU Muhammadiyah Bantul Hospital. There are 408 data on appendicitis patients that can be analyzed. Results: The WBC, neutrophils, NLR, and PLR was significantly higher in the complicated appendicitis group than in the uncomplicated group [11,5 (3.79-35.2) vs. 8.42 (3.32-39.30), p<0.0001; 8.63 (2.359-2.647) vs. 5.446 (1.691-35.960), p<0.0001; 5.65 (0.95-23.86) vs.3.82 (0.81-23.86), p<0.0001; 168.57 (37.27-974.03) vs.139.40 (56.84-1274.31), p<0.0001, respectively] followed by a significantly lower lymphocyte count [1.709 (0.154-5.71) vs. 2.094 (0.401-5.812), p<0.0001, respectively]. The area under the receiver operating characteristic (ROC) curve, cutoff point, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and likelihood ratio of NLR for diagnosis of complicated appendicitis were 0.76, >2.84, 75.21%, 62.65%, 74.6%, 63.4%, 2.01, 0.40, respectively. In contrast, an area under ROC curve, cutoff point, sensitivity, specificity, PPV, NPV, and likelihood ratio of PLR for differentiating complicated and uncomplicated appendicitis were 0.605, >140.6, 65.70%, 51.81%, 66.5%, 50.9%, 1.36, and 0.66 respectively. Conclusion: The cutoff values of NLR (>2.84) and PLR (>140.6) were significant diagnostic parameters for complicated appendicitis (p = 0.0001). Hence, NLR and PLR can assist in diagnosing complicated appendicitis.
PENGARUH BERWUDHU TERHADAP TINGKAT KECEMASAN SUAMI DALAM MENGHADAPI ISTRI PRE OPERASI SECTIO CAESAREA DI RS MAWADDAH MEDIKA: The Effect of Ablution on Husband's Anxiety Level in Facing Pre-Operation Sectio Caesarea Wife at Mawaddah Medika Hospital Yulianti, Indra; Tri Ratnaningsih; Amar Akbar
Jurnal Ilmiah Keperawatan (Scientific Journal of Nursing) Vol. 10 No. 1 (2024): JIKep | Februari 2024
Publisher : LPPM STIKES Pemkab Jombang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33023/jikep.v10i1.1951

Abstract

Pendahuluan: Fenomena dalam menghadapi persiapan dan tindakan operasi sectio caesarea banyak ditemui suami yang mengalami kecemasan. Suami merupakan orang terdekat dengan istri, sehingga menghadapi istri yang akan menjalni sectio caesarea suami akan merasakan cemas. Cara non farmakologis menurunkan kecemasan adalah teknik relaksasi, psikoterapi dengan hipnoterapi dan hidroterapi, Salah satunya dengan berwudhu.  Tujuan: mengetahui Pengaruh Berwudhu Terhadap Tingkat Kecemasan Suami Dalam Menghadapi Istri Pre Operasi Sectio Caesarea di RS Mawaddah Medika. Metode: menggunakan quasy experimental dengan pendekatan control group pretest-post test design. Populasi dalam penelitian ini adalah semua suami yang sedang menghadapi istri pre operasi SC di RS Mawaddah Medika pada bulan Mei 2023 sebanyak 58 orang. Teknik sampling penelitian ini adalah consecutive sampling dengan kurun waktu 1 bulan. Besar sampel yang memenuhi kriteria penelitian adalah 32 orang yang terbagi menjadi 16 orang kelompok eksperimen dan 16 orang kelompok kontrol. Instrumen penelitian menggunakan SOP berwudhu dan kuesioner HARS. Hasil: sebelum berwudhu sebagian besar responden pada kelompok eksperimen mengalami kecemasan sedang yaitu 11 orang (69,8%), dan sesudah berwudhu sebagian besar responden pada kelompok eksperimen mengalami kecemasan ringan yaitu 11 orang (69,8%). Hasil uji Paired t test menunjukkan rata-rata skor kecemasan responden sebelum berwudhu sebesar 23,25 dan sesudah berwudhu sebesar 19,81 sehingga terjadi penurunan skor kecemasan dengan pvalue=0,000. Kesimpulan: Wudhu memberikan akupresur pada ratusan titik akupunktur yang bersifat reseptor terhadap stimulus berupa basuhan, gosokan, usapan, dan tekanan/urutan dengan menggunakan air akan menghasilkan terapi akupresur dan hidroterapi yang dapat mengurangi kekejangan menjadi rileks.
Fostering students’ motivation to learn mathematics through steam project using 4DFrame Toolkit Ratnaningsih, Tri
Math Didactic: Jurnal Pendidikan Matematika Vol 8 No 3 (2022): September - Desember 2022
Publisher : Universitas PGRI Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33654/math.v8i3.1442

Abstract

Salah satu dampak pandemi pada pendidikan adalah proses pembelajaran yang harus berubah menjadi pembelajaran online. Beberapa siswa tidak siap menerima perubahan ini sehingga menurunkan motivasi belajar matematika. Guru harus menemukan cara baru agar motivasi belajar meningkat. Salah satunya menggunakan pendekatan STEAM. Oleh karena itu, penelitian ini bertujuan untuk mengetahui apakah proyek STEAM menggunakan 4Dframe mampu meningkatkan motivasi belajar matematika siswa. Dalam penelitian ini siswa belajar tentang segitiga dan segiempat dengan membuat bola dari sedotan dan merancang “Taxi Ijen” menggunakan 4Dframe. Penelitian ini merupakan penelitian tindakan kelas dengan dua siklus. Partisipan penelitian adalah 15 siswa kelas VII SMPN 3 Arjasa. Instrumen yang digunakan adalah angket dan lembar observasi. Analisis data menggunakan analisis deskriptif dan statistik deskriptif. Hasil lembar observasi menunjukkan peningkatan aktivitas siswa sebesar 28,8%. Namun pada indikator keaktifan siswa seperti bertanya, menjawab pertanyaan, dan berpendapat masih memiliki nilai di bawah 75%. Sedangkan hasil angket motivasi menunjukkan bahwa motivasi belajar siswa mengalami peningkatan, ditunjukkan dengan 0% siswa memiliki motivasi rendah, 6,67% memiliki motivasi sedang, 67,67% memiliki motivasi tinggi, dan 26,67% memiliki motivasi sangat tinggi. Hasil tersebut menunjukkan bahwa proyek STEAM menggunakan 4Dframe dapat meningkatkan motivasi belajar matematika siswa kelas VII SMPN 3 Arjasa.