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Cardiovascular Disease Risk Prediction Models: Limitations and Future Prospects Samsu, Nur
Clinical and Research Journal in Internal Medicine Vol. 6 No. 1 (2025): Volume 6 No 1, May 2025
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2025.006.01.01

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Intradialytic Hypotension: Is Reducing Extracorporeal Blood Flow Rate an Appropriate Intervention? Samsu, Nur
Indonesian Journal of Kidney and Hypertension Vol 2 No 1 (2025): Volume 2 No. 1, April 2025
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v2i1.185

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The association of monocyte-to-lymphocyte and neutrophil-to-lymphocyte ratios with CIMT in HD and CAPD populations Baridwan, Fakhri; Samsu, Nur; Winoto, Eden
Deka in Medicine Vol. 2 No. 2 (2025): August 2025
Publisher : PT. DEKA RESEARCH INSTITUTE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69863/dim.2025.e680

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BACKGROUND: Chronic kidney disease (CKD) carries a high risk of cardiovascular complications due to atherosclerosis, which is exacerbated by chronic inflammation. The neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) are emerging inflammatory markers with potential to predict atherosclerotic risk. OBJECTIVES: To evaluate the association between NLR and MLR values with carotid intima-media thickness (CIMT) in CKD patients undergoing hemodialysis and continuous ambulatory peritoneal dialysis (CAPD). METHODS: This observational cross-sectional study was conducted at Dr. Saiful Anwar General Hospital, Malang, between July and December 2024. Data on baseline characteristics, laboratory results, and CIMT were obtained from medical records and carotid ultrasonography. Statistical analyses included t-tests, Mann-Whitney tests, and Pearson or Spearman correlation tests, depending on data distribution. RESULTS: A total of 97 CKD patients were included (45 on CAPD and 52 on hemodialysis). NLR values were significantly higher in the CAPD group compared to the hemodialysis group (p = 0.0253), while MLR did not differ significantly. CIMT was significantly higher in the hemodialysis group (p = 0.0035). In the CAPD group, MLR was significantly correlated with CIMT (r = 0.3543; p = 0.0169), whereas no significant correlation was observed in the hemodialysis group. NLR was not significantly associated with CIMT in either group. Subgroup and ROC analyses indicated that neither NLR nor MLR could accurately differentiate elevated CIMT from normal. CONCLUSION: MLR is associated with CIMT in patients undergoing CAPD, while NLR does not show a significant association with CIMT in either dialysis group.
Jurnal Ilmiah di Indonesia: Kondisi Masa Lalu, Saat Ini dan Potensi Kedepan Samsu, Nur
Jurnal Klinik dan Riset Kesehatan Vol 1 No 1 (2021): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.01.1.1

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Alhamdulillah, atas berkat dan rahmat Tuhan Yang Maha Esa, akhirnya redaksi Jurnal Klinik dan Riset Kesehatan (JK-RISK) dapat menerbitkan edisi perdananya. JK-RISK merupakan jurnal ilmiah online, open access, dan peer-reviewed yang dikelola oleh tim Penelitian dan Pendidikan Rumah Sakit Umum Daerah dr. Saiful Anwar, Malang, Indonesia. JK-RISK bertujuan utama untuk menyebarluaskan informasi dibidang Kesehatan dan Kedokteran, sehingga menambah khazanah ilmu pengetahuan, mengembangkan ilmu pengetahuan dan teknologi serta mendorong semakin meningkatnya kuantitas dan kualitas penulisan artikel ilmiah di Indonesia pada umumnya.
Strategi Memerangi Resistensi Antibiotik Samsu, Nur
Jurnal Klinik dan Riset Kesehatan Vol 2 No 1 (2022): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.1.1

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Ambulatory Blood Pressure Monitoring (ABPM): Prosedur, Interpretasi dan Penggunaan Klinik Samsu, Nur
Jurnal Klinik dan Riset Kesehatan Vol 2 No 3 (2023): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.3.4

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Mengingat peran penting hipertensi sebagai salah satu penyebab utama morbiditas dan mortalitas prematur global, maka untuk diagnosis dan tatalaksana hipertensi secara tepat, hal yang sangat penting adalah melakukan pengukuran tekanan darah (TD) yang tepat. Secara historis, diagnosis, tatalaksana, dan prediksi risiko kematian pada pasien hipertensi didasarkan pada pembacaan TD di klinik. Namun, pembacaan TD di klinik terbukti tidak selalu dapat mencerminkan TD pasien yang sebenarnya. Dilain pihak, telah banyak bukti yang menunjukkan bahwa ambulatory blood pressure monitoring (ABPM) adalah prediktor yang lebih baik untuk kejadian kardiovaskular utama dibandingkan pengukuran TD di klinik. ABPM mengurangi jumlah pembacaan yang salah, bersamaan dengan manfaat tambahan untuk memahami variabilitas dinamis TD. ABPM memungkinkan pencatatan pengukuran TD setiap 15 – 30 menit dalam 24 jam dan mengevaluasi berbagai parameter seperti TD rata-rata 24 jam, TD rata-rata siang hari, TD rata-rata malam hari, dan persentase penurunan TD pada malam hari. Tulisan ini fokus pada pentingnya ABPM, kelebihan dan keterbatasannya dibandingkan dengan pengukuran TD klinik standar serta prosedur dan interpretasinya dalam mendiagnosis dan melakukan tatalaksana hipertensi secara lebih tepat
Diagnosis dan Tatalaksana Hipertensi Krisis Samsu, Nur
Jurnal Klinik dan Riset Kesehatan Vol 3 No 1 (2023): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.03.1.6

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Hypertensive crises are divided into emergency and urgent hypertension. For most doctors, the differences between these two types of hypertensive crisis present their own challenges, especially in terms of therapy and follow-up. The main distinguishing feature of these two types of hypertensive crisis is the presence of ongoing acute target organ damage, not the degree of blood pressure (BP). A hypertensive emergency is a true medical emergency, which generally requires immediate lowering of BP, in an intensive care unit and short-term, easily titrated intravenous antihypertensive drug therapy. Common management strategies are based on hypertension-specific organ damage (HMOD); the onset of HMOD, especially time-sensitive ones such as acute ischemic stroke, acute ST-elevation myocardial infarction; and availability of facilities and resources. A hypertensive emergency is a state of severe or significant increase in BP but without acute damage to target organs. This type of hypertension does not require rapid lowering of BP, and can be treated on an outpatient basis with appropriate oral medications.
Tantangan Terhadap Tatalaksana Sindroma Nefrotik Samsu, Nur
Jurnal Klinik dan Riset Kesehatan Vol 3 No 1 (2023): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.03.1.1

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Apakah Perlu Ada Subspesialis Nefro-Kardiologi? Samsu, Nur
Jurnal Klinik dan Riset Kesehatan Vol 4 No 1 (2024): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.1.1

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Heparin: Indikasi Klinis dan Strategi Pencegahan Risiko Perdarahan Samsu, Nur
Jurnal Klinik dan Riset Kesehatan Vol 5 No 1 (2025): Edisi Oktober 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.05.1.1

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