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All Journal Jurnal Nalar Pendidikan Jurnal Ilmu Perpustakaan Sainteknol : Jurnal Sains dan Teknologi Majalah Obat Tradisional Transformatika: Jurnal Bahasa, Sastra, dan Pengajarannya Majalah Farmaseutik HIKMAH : JURNAL PENDIDIKAN AGAMA ISLAM Jurnal Mandala Pharmacon Indonesia Jurnal FARMAKU (Farmasi Muhammadiyah Kuningan) JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan Jurnal Kesehatan Tambusai Well Being JEBDEKER: Jurnal Ekonomi, Manajemen, Akuntansi, Bisnis Digital, Ekonomi Kreatif, Entrepreneur Center of Knowledge JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Medika Respati : Jurnal Ilmiah Kesehatan Kompeten: Jurnal Ilmiah Ekonomi dan Bisnis Jurnal Abdimas Jatibara Academic Hospital Journal Asian Journal of Management, Entrepreneurship and Social Science Indonesian Journal of Pharmacology and Therapy Jurnal Rekam Medic
Ika Puspita Sari
Biology Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri Semarang
Religion Arts Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Nursing Public Health Social Sciences Other

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ASUHAN KEPERAWATAN PADA KLIEN YANG MENGALAMI DIABETES MILLITUS TIPE II DENGAN MASALAH KEPERAWATAN GANGGUAN POLA TIDUR MENGGUANAKAN RELAKSASI OTOT PROGRESIF DIRUANG NAKULA RSUD JOMBANG parakoso, gigih; Fitriyah, Erna Tsalatsatul; Sari, Ika Puspita; Roni, Faishol; Wijaya, Arif
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.35826

Abstract

Penyakit Diabetes Mellitus Tipe II dapat menyebakan gangguan pola tidur ditandai dengan poliura (banyak kencing), polidipsi (banyak minum), poliphagi (banyak makan) dan gangguan lainnya yang terjadi pada malam hari yang dapat mengganggu tidurnya. Pasien Diabetes Mellitus Tipe II mengalami kualitas tidur tidak nyenyak yang dapat mengganggu metabolisme dan dapat memicu mencari makan berlebihan sehingga bisa mengacaukan kinerja insulin dan pengendalian gula darah menjadi buruk sehingga menyebabkan kematian. Tujuan dari penelitian ini adalah melaksanakan Asuhan Keperawatan pada klien Diabetes Mellitus Tipe II dengan masalah keperawatan gangguan pola tidur menggunakan terapi relaksasi otot progresif. Metode dari penelitian ini menggunakan studi kasus subjek 2 klien Diabetes Mellitus Tipe II dengan masalah keperawatan gangguan pola tidur dilakukan asuhan keperawatan selama 3 hari berturut-turut menggunakan intervensi relaksasi otot progresif. Hasil dari penelitian ini telah didapatkan pada kedua klien dengan masalah keperawatan gangguan pola tidur dengan masalah sulit tidur telah berkurang setelah diberikan terapi relaksasi otot progresif selama tiga hari. Diskusi dan Kesimpulan dari penelitian ini adalah relaksasi otot progresif digunakan sebagai terapi tambahan untuk mengendalikan gangguan pola tidur dan mengurangi insomnia pada pasien Diabetes Mellitus Tipe II secara non farmakologis.
Evaluasi Penggunaan Antibiotik pada Community Acquired Pneumonia Candraningrat, I Dewa Agung Ayu Diva; Andayani, Tri Murti; Sari, Ika Puspita
Majalah Farmaseutik Vol 20, No 4 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v20i4.92448

Abstract

Community Acquired Pneumonia (CAP) merupakan infeksi yang terjadi di paru-paru yang didapatkan dari komunitas dan sering meningkatkan angka rawat inap di rumah sakit. Bakteri yang paling umum menjadi penyebab CAP adalah Streptococcus pneumoniae, Mycoplasma pneumoniae, dan Chlamydophila pneumoniae. Berdasarkan pada pedoman American Thoracic Society (ATS) dan Infectious Disease Society of America (IDSA), penggunaan terapi antibiotik pada pasien CAP dinilai berdasarkan stabilitas klinisnya. Ulasan artikel ini bertujuan untuk membandingkan hasil evaluasi penggunaan antibiotic yang dilihat dari stabilitas klinis dan keamanannya. Ulasan artikel bertujuan untuk membandingkan hasil penelitian yang diperoleh dari PubMed sebagai literatur dan diagram PRISMA sebagai guideline pada proses seleksi artikel. Berdasarkan hasil ulasan artikel diperoleh 10 artikel yang sesuai dengan topik dan tujuan. Dapat disimpulkan bahwa penggunaan antibiotik golongan betalaktam atau fluorokuinolon memiliki efikasi dan keamanan yang baik untuk pasien CAP
PERBEDAAN KEPUASAN PASIEN BPJS DAN PASIEN UMUM PADA BAGIAN PENDAFTARAN RAWAT JALAN DI RUMAH SAKIT KABUPATEN SIDOARJO TAHUN 2024 Atika, Atika; Abdurrohman KM, M. Sa’id; Sari, Ika Puspita
Medika Respati : Jurnal Ilmiah Kesehatan Vol 19, No 3 (2024)
Publisher : Universitas Respati Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35842/mr.v19i3.1191

Abstract

Latar belakang: Ketidakpuasan pasien di Rumah Sakit Kabupaten Sidoarjo khususnya pasien BPJS dan umum masih terdapat beberapa keluhan terkait pelayanan yang diberikan oleh rumah sakit yang disampaikan melalui ulasan website. Tujuan: untuk mengetahui mengetahui perbedaan kepuasan pasien BPJS dan Pasien Umum di bagian pendaftaran rawat jalan. Metode: penelitian ini menggunakan deskriptif kuantitatif dengan pendekatan cross sectional. Populasi pada penelitian ini berjumlah 10.272 responden, besar sampel 100 responden, teknik Pengambilan sampel dengan menggunakan teknik rancangan acak dengan sederhana (Simple Random Sampling), waktu penelitian dilaksanakan pada bulan Januari 2024, teknik analisis yang digunakan uji beda Mann Whitney U-test. Hasil: Responden BPJS yang merasa puas 28 orang (56%), dan yang merasa sangat puas 22 orang (44%). Responden Umum yang merasa puas 6 orang (12%), dan yang  merasa sangat puas 44 orang (88%). Selain itu, hasil penelitian ini juga mennjukkan bahwa ada perbedaan kepuasan Pasien BPJS dan Pasien Umum di bagian pendaftaran rawat jalan di Rumah Sakit Kabupaten Sidoarjo dengan nilai p value 0,000 (p < 0,05). Kesimpulan: ada perbedaan kepuasan Pasien BPJS dan Pasien Umum di bagian pendaftaran rawat jalan di Rumah Sakit Kabupaten Sidoarjo, Rumah Sakit Kabupaten Sidoarjo disarankan untuk meningkatkan kepuasan pasien dengan memberikan pelatihan  kepada petugas pendaftaran tentang pelayanan.
Ambroxol Therapy as an Antibiofilm Candidate in Diabetic Ulcer Patients Wahyuddin, Munifah; Sari, Ika Puspita; Asdie, Rizka Humardewayanti; Nuryastuti, Titik
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 1 (2025): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i1.791

Abstract

Patients with diabetic ulcers are susceptible to infection because the tissue in their extremities is constantly exposed to various pathogenic bacteria, so biofilm formation plays an important role in developing the disease. Based on previous studies, ambroxol can inhibit the formation of biofilm bacteria. The purpose of this study was to identify biofilm-forming bacteria, prove that ambroxol has the potential to inhibit and eradicate biofilms formed by bacteria in diabetic ulcers and analyse the potential of ambroxol in eradicating biofilms formed by bacteria in diabetic ulcer patients based on PEDIS and SEM scores. The method used was a 96-well microtiter plate assay (MtPA) with crystal violet and MTT staining techniques, a test using human samples with a quasi-experimental method with sampling carried out by nonprobability sampling. The samples used were diabetic ulcer patients with culture results forming biofilms. The results obtained identified 3 clinical isolates that formed biofilms with 100% Gram-negative bacteria, including two isolates of Pseudomonas aeruginosa and one isolate of Escherichia coli with the ability to form biofilms are moderate. Ambroxol effectively inhibits and eradicates 50% of biofilms formed by diabetic ulcer bacteria at a minimum concentration of 1 mg/ml. Based on the PEDIS score and SEM images of diabetic ulcer patients, there was a decrease in the PEDIS score in each patient, with an average score of 2. Several studies have demonstrated that combining Ambroxol with antimicrobials can synergistically enhance the antibiotic's efficacy against biofilms. The co-administration of Ambroxol with other antimicrobial agents represents a promising approach to improving antibiotic effectiveness. Nevertheless, careful consideration must be given to the concentration of Ambroxol used.
Pengaruh Kompetensi Sumber Daya Manusia, Sistem Informasi Pengelolaan Keuangan Daerah, dan Pengendalian Internal terhadap Kualitas Laporan Keuangan Badan Layanan Umum Daerah (BLUD) pada Puskesmas Kabupaten Blora Ariyanti, Irma; Mazidah, Nurul; Sari, Ika Puspita
Kompeten: Jurnal Ilmiah Ekonomi dan Bisnis Vol. 4 No. 1 (2025): Juli 2025
Publisher : PT Seval Literindo Kreasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57141/kompeten.v4i1.208

Abstract

Tujuan penelitian ini  untuk mengetahui berapa besar pengaruh kompetensi sumber daya manusia, sistem informasi pengelolaan keuangan daerah dan pengendalian internal terhadap kualitas laporan keuangan Badan Layanan Umum Daerah (BLUD) pada puskesmas Kabupaten Blora. Jenis data yang digunakan dalam penelitian ini adalah data kuantitatif. Sampel yang digunakan  penelitian ini berjumlah 52 orang pegawai BLUD Puskesmas Dinas Kesehatan Kabupaten Blora dengan kriteria petugas akuntansi dengan status PNS dan non PNS, menggunakan metode penentuan sampel yaitu purposive sampling. Pengumpulan data dilakukan dengan menyebarkan kuesioner berupa link google form melalui aplikasi whatsapp group kepada petugas akuntansi BLUD puskesmas di Kabupaten Blora dan diolah menggunakan Data Analysis Microsoft Excel. Analisis data yang dilakukan pada penelitian ini menggunakan regresi linier berganda. Hasil penelitian ini menunjukkan bahwa kompetensi sumber daya manusia, sistem informasi pengelolaan keuangan daerah dan pengendalian internal berpengaruh positif dan signifikan terhadap kualitas laporan keuangan Badan Layanan Umum Daerah (BLUD) pada puskesmas Kabupaten Blora.
Assessment of one-year overall survival among stage III breast cancer patients Darwito; Sari, Ika Puspita; Wijayana, Singgih; Mahardinata, Nur Azid; Anwar, Sumadi Lukman; Ridhayani, Firda
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 2, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss2.art6

Abstract

Background: The results of a comprehensive diagnosis, combined with the individual's general state, establish the appropriate therapeutic care for breast cancer patients. These management disparities have an impact on clinical outcomes, which may influence patient survival. The evaluation process of breast cancer management is essential as a strategy to boost the therapy's effectiveness in the future year. Objectives: Assessing survival rate, one-year overall survival, among stage III breast cancer patients.Methods: An observational study was conducted comprising a retrospective cross-sectional study. Data collected retrospectively from the medical record followed a total sampling technique. This study included patients with breast cancer as a main diagnosis with or without comorbidities and aged ≥ 18 years when undergoing their first diagnosis. Moreover, the exclusion criteria were patients who had incomplete medical record data, undergoing breast cancer treatment at other healthcare facilities, unspecified clinical stage, and patients who had been diagnosed with non-stage III breast cancer. The survival time of the participants is defined as the number of months from initial diagnosis to their last status (alive, died, or loss of follow-up). One-year overall survival was projected using the Kaplan-Meier curve and presented as a percentage with a 95% confidence interval. Results: Of the 23 patients with stage III breast cancer and the mean age was 57.39 ± 10.417 years. The one-year overall survival for stage III breast cancer was 78.3%. In addition, metastases conditions were associated with worse one-year overall survival compared to patients without metastases (40.0% vs 88.9%, p=0.028).Conclusion: The survival rate of breast cancer patients remains lower than in another recent study from Indonesia. This indicates the requirement of treatment strategies evaluation.
HUBUNGAN KUALITAS TIDUR DENGAN PRESTASI BELAJAR REMAJA DI PONDOK PESANTREN MANBA’UL HIKAM PUTAT TANGULANGGIN SIDOARJO Nafi’a, Fikrotul Ilman; Firiyah, Erna Tsalatsatul; Sari, Ika Puspita
WELL BEING Vol 5 No 1 (2020): Well Being
Publisher : LPPM STIKes Bahrul Ulum Jombang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51898/wb.v5i1.53

Abstract

Sleep is a basic need for everyone. Sleep quality is said to be good if it does not show signs of sleep deficiency, such as swelling in the eyelids, and dark areas around the eyes. Many sleep conditions are found among teenagers who can later cause many effects, such as reduced learning concentration, memory, thinking and health disorders. The purpose of this research is to know the relationship between sleep quality with adolescent learning achievements. The research uses the collation analytic design with the cross-sectional retrospective approach. Samples used as much as 60 respondents. The sampling technique used is purposive sampling. Data collection using questionnaires and report value. The results of the study gained good sleep quality with good learning achievement as many as 11 respondents (18.3%), while poor sleep quality with good learning achievement as many as 45 respondents (75.0%). Based on the statistical test there is a value of rs = 0.000 with P = 1,000 where p > 0.05 so that HI rejected means there is no relationship the quality of sleep and learning performance of young women at Manba'ul Hikam Boarding School Putat Tanggulangin Sidoarjo. Counseling guidance is required and motivates students to be more active in learning.
Morinda citrifolia Linn. Ethanolic-extract Improve Inflammation Condition in Acetic Acid-induced Colitis Ulcerative Mice Models Utami, Tri Fitri Yana; Sahid, Muhammad Novrizal Abdi; Sari, Ika Puspita; Sasmito, Ediati
Majalah Obat Tradisional Vol 30, No 2 (2025)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.95065

Abstract

Ulcerative Colitis (UC) is a chronic inflammatory disorder affecting the colon, characterized by recurrent episodes and involving multifaceted etiological factors in its pathogenesis. This study aims to explore the pharmacological effect of Morinda citrifolia Linn. fruit ethanolic-extract (MFE) in UC. The UC mice model was induced using 2% acetic acid administered per-rectal. Subsequently, mice were categorized into six groups, comprising a normal control, negative control, positive control, and three MFE treatment groups (100mg/kgBW; 200mg/kgBW; 400mg/kgBW). Colitis severity was assessed by scoring system to obtain the Disease Activity Index (DAI) and Hematoxylin-Eosin (HE) staining. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay was employed to determine the free radical scavenging activity. MFE exhibited notable antioxidant activity, with an IC50 value of 0,553 mg/ml. Notably, MFE administration led to a discernible reduction in DAI scores, with MFE treatment demonstrating improved inflammation condition compared to the negative control from day 6 through day 11. Furthermore, immune cell infiltration within colonic tissue was markedly attenuated in the MFE-treated group compared to the negative control group. Evaluation of colon tissue damage revealed scores of 5.7, 4.2, and 3 for MFE doses of 100 mg/kg, 200 mg/kg, and 400 mg/kg, respectively, whereas the positive control group exhibited a score of 3, indicating superior tissue preservation. Notably, these scores contrasted starkly with the negative control group, which registered a damage score of 11.8. These findings exhibit the MFE potential as a therapeutic intervention for UC owing to its pharmacological properties, underscoring its potential as a natural remedy in UC management.
Clinically significant of drug-drug interactions among children: a review Ridhayani, Firda; Sari, Ika Puspita; Andayani, Tri Murti
Indonesian Journal of Pharmacology and Therapy Vol 5 No 3 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.9663

Abstract

Drug-drug interactions among children are a getting along concern in health care settings, specifically intensive care units, as sources of adverse drug events that may affect patient condition. Children admitted to pediatric intensive care unit are more prone to drug-drug interactions owing to the diseases and medications complexity. This condition could put the patient at high risk of harm, particularly with his critical condition, so need intense considerations from clinical practitioners to prevent adverse drug events caused by potential drug-drug interactions. This article’s review attempts to explore the important drug-drug interactions among children, including explaining the drug combination, mechanism, and related adverse drug events to help health practitioners recognize it earlier before prescribing the medication. This article’s review explored previous research results from PubMed and Google Scholar as literature resources and PRISMA flow chart as protocol for article selection process. A total of 9 articles discussed comprehensively about the type of drug combinations, mechanism of drug-drug interactions, and associated adverse drug events with significant drug-drug interactions that commonly occurred in children’s patient during the treatment. The drug-drug interaction including midazolam-phenobarbital, cannabidiol-clobazam, Paxlovid-tacrolimus, inhaled fluticasone propionate-lopinavir/ritonavir, rifampicin-warfarin, clofazimine-moxifloxacin, benzatropine-haloperidol, and enalapril-spironolactone. In conclusion, gaining a better understanding of drug-drug interactions among children will empower healthcare professionals to develop useful strategies to recognize, manage, and prevent various types of pharmacokinetic and pharmacodynamic interactions. Especially at different stages in terms of age, physiology, and complexity of the disease in children.
Evaluasi Kuantitatif Penggunaan Antibiotik Pada Anak dengan Pneumonia di Rumah Sakit Akademik Universitas Gadjah Mada A., Diki Aprianto; Sari, Ika Puspita; Yasin, Nanang Munif
Majalah Farmaseutik Vol 21, No 3 (2025)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v21i3.97655

Abstract

Infeksi parenkim pada paru merupakan salah satu penyebab terjadinya penyakit pneumonia, tepatnya dikantung kecil yang disebut alveoli. Untuk mengurangi hal itu terjadi diperlukan adanya intervensi perawatan yaitu penggunaan antibiotik sebagai salah satu terapi utama untuk penyakit yang disebabkan oleh bakteri Streptococcus pneumoniae. Pada penelitian ini bertujuan untuk mengetahui jumlah penggunaan antibiotik empiris dan/atau definitif pada pasien anak dengan pneumonia di Rumah Sakit Akademik Universitas Gadjah Mada. Penelitian ini merupakan penelitian observasional deskriptif dengan desain penelitian cross-sectional pada pasien rawat inap yang berusia 0 hingga £18 tahun. Hasil penelitian ini diperoleh penggunaan antibiotik pasien anak dengan pneumonia periode 1 Januari hingga 31 Desember 2022 didapatkan nilai total DDD sebesar 1248,35 DDD/100 hari rawat dengan nilai DDD antibiotik tertinggi adalah gentamisin sejumlah 538,16 DDD/100 hari rawat dan nilai DDD antibiotik terendah adalah seftazidim 2,39 DDD/100 hari rawat inap. Segmen yang termasuk dalam DU 90% diantaranya gentamicin, sefiksim dan azitromisin, sefotaksim serta segmen yang temasuk dalam DU 10% diantaranya seftriakson, ampisillin, siprofloksasin, amoksisillin klavulanat, amoksisillin, amikasin, kotrimoksazol, dan seftazidim.
Co-Authors A., Diki Aprianto Abdurrohman KM, M. Sa’id Amin Retnoningsih Anwar, Sumadi Lukman Arif Wijaya Arifin, Shokhibul Ariyanti, Irma Arwani, M. Atika Atika Azizah, Zulfi Bathari, Anggraini Citra Ryshang Batubara, Naufal Akbar Bayu Bakti Angga Santoso Candraningrat, I Dewa Agung Ayu Diva Darwito Dewi Latifatul Ilma Dewi, Aprilya Tunggo Dicky M. Rizal, Dicky M. Djoko Wahyono Dyawati, Nova Ediati Sasmito Endang Lukitaningsih Enni Suwarsi Rahayu Estriningsih, Endang Fairuza, Najwa Falihah, Atika Hanum Firda Ridhayani Firiyah, Erna Tsalatsatul Fita Rahmawati Fitriyah, Erna Tsalasatul Harahap, Amira Mufidah I Dewa Putu Pramantara Ibrahim, Muhammad Malik Irfan Muris Setiawan Karundeng, Glory Claudia Kurnia, Ita Lubis, Zulfahmi Mahardinata, Nur Azid MAULANA, AGUNG FIRMAN Mazidah, Nurul Mecca Arfa, Mecca Muhammad Husaini Muhammad Nurul Huda Munadi, Windya Rizki Dwi Mustofa Mustofa Muvita Rina Wati Nabila, Lathifa Nafi’a, Fikrotul Ilman Nanang Munif Yasin Nurkhalika, Rachmi Nurul Huda Nurwulandari , Andini parakoso, gigih Pratama, Anton Purwaningtyastuti, Eni Rakhmawati, Fitria Ratna Ratna Rizka Humardewayanti Asdie Roni, Faishol Rufaidah, Alfin Rumiyati, Rumiyati Sahid, Muhammad Novrizal Abdi Selamet, Ni Made Dwi Antika Simamora, Dian Mutiara Siti Rahayu Sulistyawati, Ety Diana Sulistyawaty, Ety Diana Taufik, Ganjar Titik Nuryastuti Tri Murti Andayani Utami, Tri Fitri Yana Wahyuddin, Munifah Wiganata, Siken Agil Wijayana, Singgih Wiyatami, Monia Agni Yuni, Ika Yusmanisari, Eka Zahro, Indira Munifatus