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Abdul Karim
Universitas Labuhanbatu
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Journal : Jurnal Teknik Informatika (JUTIF)

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Machine Learning Decision Support System for Heart Disease Prediction with Optuna and Threshold Optimization Ramdhan, William; Hutahaean, Jeperson; Jollyta, Deny; Karim, Abdul
Jurnal Teknik Informatika (Jutif) Vol. 7 No. 2 (2026): JUTIF Volume 7, Number 2, April 2026
Publisher : Informatika, Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52436/1.jutif.2026.7.2.5684

Abstract

Cardiovascular disease remains a major global health challenge, necessitating accurate and reliable decision support systems for early detection. This study proposes a machine learning–based decision support system that integrates ensemble learning, automated hyperparameter optimization using Optuna, and decision threshold tuning. The system was evaluated using several baseline machine learning models, including Logistic Regression, SVM, KNN, Decision Tree, and Random Forest, with the Random Forest model selected for optimization. Hyperparameter tuning with Optuna and decision threshold optimization led to a significant improvement in accuracy (95.0%) and ROC–AUC (0.977), with the optimized model outperforming all baseline models. This approach demonstrates improved sensitivity, reduced false negatives, and enhanced predictive performance, offering a clinically reliable tool for early heart disease detection. The results emphasize the importance of model optimization and decision threshold calibration in clinical decision support systems.
Co-Authors Afrendi, Mohammad Agus Perdana Windarto Agustina Sidabutar Agustina, Asri Widya Ahyuna Ahyuna, Ahyuna Aldiansyah, Ferry Alfarisi Pasaribu, Ahmad Ambiyar, Ambiyar Andi Ernawati Andi Ernawati Andriani, Titi Aritonang, Putri Armasari, Selly Arridha Zikra Syah Asyahri Hadi Nasyuha Awfa, Qifari Bangun, Budianto Bernadus Gunawan Sudarsono Bobbi Kurniawan Nasution, Muhammad Cheylani Lukito, Salwa Christiorenfa Br Haloho, Agatha Daulay, Nelly Khairani Dayu Sari, Arini Deny Jollyta Dhea Ananda, Tasya Dito Putro Utomo Dwika Asrani Dwika Assrani Efendi Hutagalung, Jhonson Efendi, Safri Erlin Windia Ambarsari Fadli, Muhammad Bagus Fadlina Fahmi Rizal Febriani, Budi Fifto Nugroho Garuda Ginting Guidio Leonarde Ginting Harahap, Armyka Pratama Hasibuan, Awaludin Heni Pujiastuti Hersatoto Listiyono Hidayatullah, Muhammad I Wayan Sugianta Nirawana Imam Saputra Indah Sari, Leni Indrayani, Puput Iwan Purnama Iwan Purnama Jahril Jeperson Hutahaean Kraugusteeliana Kraugusteeliana Kurniawan Nasution, Muhammad Bobbi Kusmanto Kusmanto Kusmanto Kusmanto M. Rafi Mardinata, Erwin Marha As, Pawa Niassa Meryance Viorentina Siagian Mesran, Mesran Mhd Ali Hanafiah Mhd Bobbi Kurniawan Nasution Moustafa H. Aly Muhammad Bobbi Kurniawan Nasution Muhammad Hamka Muhammad Syahrizal Nababan, Dosmaida Nasution, Mhd Bobbi Kurniawan Nasution, Muhammad Bobbi Kurniawan Natalia Silalahi Nona Oktari Nurlela Nurlela Nurliadi Pane, Rahmadani Pane, Siddik Pohan, Tatang Hidayat Poningsih Pratama, Armyka Prayetno, Sugeng Prayetno, Sugeng Prayetno Purba, Elvitrianim Purba, Elvitrianim Putra Juledi, Angga Putri, Nathania Rahman, Ben Ramdhan, William Rizal, Chairul Rohani Rohani Roslidar Saidi Ramadan Siregar Saludin Muis Sartika Br Siregar, Amanda Sempurna, Teguh Shinta Esabella Siagian, Yessica Siddik Siregar, Anwar Sinulingga, Raja Ingata Siregar, Feby Khairunnisya Siti Sahara Nasution Soeb Aripin Suha Alvita Suhada, Karya Sundari Retno Andani Supiyandi Supiyandi Suryadi, Sudi Sutrino Dwi Raharjo Syahputra Harahap, Hasmi Syahrial Tengku Mohd Diansyah, Tengku Mohd Triana, Dewi Trianovie, Sri Trianovie, Sri Unung Verawardina Uswatun Hasanah Vita S. Siregar, Siony William Ramdhan Wilson, Eric Yessica Siagian Yulizar, Isma Ahmad Yuwaldi Away Zebua, Yuniman Zulham Sitorus Zulkifli Zulkifli Zuly Budiarso