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Journal : METAMORFOSA Journal of Biological Sciences

Gambaran Histopatologi Otot Korpus Kavernosum Tikus Wistar (Rattus norvegicus) Hiperlipidemia Anak Agung Ayu Putri Permatasari; Ni Kadek Yunita Sari; I Gede Widhiantara
Metamorfosa: Journal of Biological Sciences Vol 5 No 2 (2018)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2018.v05.i02.p19

Abstract

This study aims to see the histopathology of muscle corvus cavernosum penis wistar rats (Rattus novergicus) hyperlipidemia seen in terms of thickness and picture of tissue abnormalities. Hyperlipidemia is a risk factor for erectile dysfunction ateriosklerosis in men. This research is an experimental research with one group prettest - posttest design. Samples in this study were 10 adult male aged 3-4 months wistar rats with a weight range 150-200 grams. Prior to treatment, surgery was performed for histopathology of 5-tailed rat samples at pretest. After that, sample were made with hyperhidemia by feeding fat for 50 days. Then performed surgery for histopathological preparation of corvus cavernosum muscle in posttest. The results showed that the thickness of the corvus cavernosum of the penile mouse of hyperlipidemia decreased significantly (P?0,05) when compared with the pretest group. In the histopathologic picture occurs muscle atrophy and the existence of abnormal structures of fibrotic and collagen tissue.
Potensi Ekstrak Daun Akasia (Acacia auriculiformis) sebagai Antifungi pada Candida albicans dan Identifikasi Golongan Senyawanya Ni Kadek Yunita Sari; Ni Luh Utari Sumadewi
Metamorfosa: Journal of Biological Sciences Vol 6 No 2 (2019)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2019.v06.i02.p02

Abstract

Infections caused by Candida albicans have been increased dramatically worlwide. Acacia auriculiformis is an Indonesian Indigenous plant which has limited use only for fiber needs, especially for paper industry raw materials and as a protective plant. The use of Acacia auriculiformis as a traditional medicine, especially as an antifungal, is rarely reported. The purpose of this study was to determine the potential of acacia leaf extract (Acacia auriculiformis) as an antifungal against Candida albicans growth and identification of its compound class. The potential of acacia leaf extract as antifungal was tested by Kirby-Bauer method using paper discs and identification of acacia leaf compound class was carried out by phytochemical test. The results showed that acacia leaf extract (Acacia auriculiformis) concentration of 1%, 5%, 10% have potential to be an antifungal against the growth of Candida albicans and the methanol extract compound of acacia leaves consists of saponins, tannins, alkaloids, flavonoids, steroids and phenolics. Keyword: Candida albicans, Acacia auriculiformis, antifungal
PENGARUH MUTAGEN KIMIA SODIUM AZIDA TERHADAP MORFOLOGI TANAMAN CABAI BESAR (Capsicum annuum L.) Ni Kadek Yunita Sari; Made Pharmawati; I Ketut Junitha
Metamorfosa: Journal of Biological Sciences Vol 1 No 1 (2012)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The aim of this research was to examine the effects of sodium azide at concentration of 1 mM, 2 mM, 3 mM, 4 mM and 5 mM on the morphological characters of Capsicum annuum L. The method used for the observation of morphological characters was direct observation by measuring plant height, leaf length and width as well as counting the number of leaves. The results showed that effect of sodium azide at 3 mM caused an increase in plant height, while concentration of 1 mM, 2 mM, 4 mM dan 5 mM caused a decrease in plant height. Similar trends were found for number of leaf. Leaf length and width tended to increase in sodium azide treatments.
Aktivitas Antifungi Saponin Bunga Kamboja Putih (Plumeria acuminata) pada Candida albicans ATCC 10231 Ni Kadek Yunita Sari; Ni Luh Utari Sumadewi
Metamorfosa: Journal of Biological Sciences Vol 8 No 1 (2021)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2021.v08.i01.p07

Abstract

Candida albicans is the main cause of candidiasis in Indonesia. Cases of infection due to Candida fungus have increased globally due to increasing cases of HIV / AIDS infection. White Cambodia is one type of plant that has various properties as a medicinal plant. So far several studies related to the effectiveness of natural antifungi have been carried out on the leaves of white frangipani plants. The effectiveness of antifungi in other white frangipani plant organs such as flowers is still rarely reported. The purpose of this study was to determine the saponin compound content of white frangipani flowers (Plumeria acuminata) and the effectiveness of these compounds on the growth of Candida albicans. The method used in this study: identification of antifungal saponin compounds was carried out by foam testing. Antifungal effectiveness test of saponin compounds on the growth of Candida albicans was tested by the Kirby-Bauer method. Quantitative data of inhibition zone diameters formed in each treatment were analyzed using ANOVA (Analysis of Variance) level of 5%. ANOVA analysis results were significantly different (P <0.05) followed by Duncan's test to see differences between treatments. The results showed that white frangipani saponins (Plumeria acuminata) had antifungal activity on Candida albicans as indicated by the emergence of a 7.7 mm inhibition zone (medium category). Keyword: Candida albicans, Acacia auriculiformis, antifungal, saponin
Co-Authors A.A. Ayu Putri Permatasari Adi Sofyan Ansori, Muhammad Adnyana, Gabriel Firsta Afta Daniel Zato Waruwu Anggriani, Martha Sephtia Aprodita, Ni Wayan Seila Aris Jatmiko Aryaswari, Ni Kadek Dwi Liopita Aulia Iefan Datya Buu, Ani Wini Carolina Widyawati Deswiniyanti, Ni Wayan Deswiniyanti Dylla Hanggaeni Dyah Puspaningrum Efendi, I Kadek Eka Jaya Elok Faiqotus Zahra Elok Faiqotus Zahro Endah K, Natalia Sri ENIEK KRISWIYANTI Fimaputra, Jatu Maranatha Fir, Maria Alfira Juita Garry Ganvis Jonteo Hani Gerson Feoh Hanggaeni Dyah Puspaningrum, Dylla Hasanah, Nina Huawatun I Gede Widhiantara I Ketut Junitha I Made Endra Puniawan I Made Gde Sudyadnyana Sandhika I Made Murna I Made Tegeh I Made Wisnu Adhi Putra I Putu Dedy Kastama Hardy I Wayan Rosiana IDA AYU ASTARINI K, Natalia Sri Endah Komang Ayuk Supriani Lestari, Ni Kadek Dwipayana MADE PHARMAWATI Marselinus Gede Widiarta Matius Victorino Ola Dame Mochammad Aqilah Herdiansyah Natalia Sri Endah K Ni Kadek Dwipayani Lestari Ni Kadek Wini Ewintiani Ni Komang Widiastuti Ni Luh Putu Wina Ewiantini Ni Luh Sunarsih Ni Luh Utari Sumadewi Ni Made Virginia Ni Made Wagi Ambakesari Ni Nyoman Ari Mardianti Ni Putu Widya Astuti Ni Putu Yuria Mendra Ni Wayan Deswiniyanti Ni Wayan Nursini Novaria Sari Dewi Panjaitan Panjaitan, Novaria Sari Dewi Permatasari , A.A. Ayu Putri Permatasari , Anak Agung Ayu Putri Permatasari, A. A. Ayu Permatasari Permatasari, Anak Agung Ayu Permatasari, Anak Agung Ayu Putri Permatasari, Anak Agung Ayu Putri Permatasari Putri, Fadillaisyia Riandani Putri, Ni Putu Diah Paramita Putu Angga Wiradana Putu Ayu Tantri Dewi Putu Eka Sudaryatma Rahmadi Prasetijo Rai Riska Resty Wasita Razaq, Imanuddin Rony MahaPutraUmbu Pingge Sandhika, I Made Gde Suadnyana Sri Endah K, Natalia Sri Puji Astuti Wahyuningsih Teguh Hari Sucipto, Teguh Hari Virgilia Gabreni Amleni Waruwu, Ernawati Widiiastuti, Ni Komang Wiradana , Putu Angga