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Perencanaan Ulang Struktur Bawah Gedung dengan Fondasi Tiang Pancang: Studi Kasus Proyek Pembangunan Rumah Susun Pekerja Industri Batang III JTGRSN21-03 Abimanyu Wahyu P.S.P.; Adi Prasetyo Pambudi; Soedarsono, Soedarsono; Lisa Fitriyana
Journal of Engineering and Applied Technology Vol 2 No 1 (2026): : June: Scripta Technica: Journal of Engineering and Applied Technology
Publisher : CV SCRIPTA INTELEKTUAL MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65310/715f1x10

Abstract

Pile foundations play an important role in ensuring the stability of multi storey buildings subjected to axial loads, lateral loads, and moments. In the Batang III Industrial Worker Housing Project (JTGRSN21-03), the original foundation system used bored piles. This study redesigns the foundation into spun piles with a diameter of 0.80 m and a length of 12 m under the same soil conditions and loads. The research methodology was conducted through analysis of three foundation joints. Axial bearing capacity was evaluated using the Meyerhof method, resulting in a tip resistance of 946.00 kN, skin friction resistance of 2,970.37 kN, ultimate bearing capacity of 3,916.37 kN, and allowable bearing capacity of 1,305.46 kN. Lateral bearing capacity was analyzed using the Broms method with an allowable capacity of 162.0 kN. Group pile bearing capacity was determined using the Converse Labarre method. Settlement analysis using the Vesic method showed a single pile settlement of 22.69 mm and group settlements of 50.2 mm at joint 599, 41.8 mm at joint 628, and 21.0 mm at joint 371. Plaxis analysis produced smaller settlements of 13.94 mm, 13.44 mm, and 9.19 mm. The pile cap and shear wall design is considered safe.  
Change in Adenosine Deaminase Serum Levels from Before and Six Months After Treatment in Patients with Tuberculous Lymphadenopathy Muljono, Christa Graziella; Soedarsono, Soedarsono
Jurnal Respirasi Vol. 12 No. 1 (2026): January 2026
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v12-I.1.2026.1-5

Abstract

Introduction: Tuberculous lymphadenopathy (TBLN) is challenging to both diagnose and treat. The outcome of a complete course of anti-tuberculosis (TB) drugs (ATDs) is evaluated based on clinical presentation and symptom improvement. Many clinicians administer ATDs for more than 6 months when they find residual lymphadenopathy or a paradoxical reaction. Therefore, this study assessed whether serum adenosine deaminase (ADA) levels are a suitable marker for evaluating the response to TBLN treatment and for analyzing changes in serum ADA levels from before to after 6 months of treatment with the standard ATD regimen in patients with TBLN. Methods: This prospective analytic observational study enrolled ATD-naïve patients with TBLN who received the standard 6-month ATD regimen in the TB directly observed therapy outpatient wards at Dr. Soetomo General Academic Hospital and Universitas Airlangga Hospital, Surabaya, from May 2023 to June 2024. Serum ADA levels were determined before and after treatment and compared using the Wilcoxon signed-rank test. Results: This study enrolled 22 patients, mostly female (n=14, 63.6%), with a mean age of 29.55±8.92 years old. The median serum ADA level was 18.7 (12.5-42.5) IU/L before and 13.9 (9.6-27.1) IU/L after treatment, with a significant mean decrease of -4.55 IU/L (p=0.001). Conclusion: Treatment with the standard 6-month ATD regimen decreased serum ADA levels in patients with TBLD. Therefore, serum ADA levels can be used as a follow-up test after treatment for patients with TBLN to evaluate their response to anti-TB therapy.
Potential Biomarkers and Inflammatory Modulation of Hyperbaric Oxygen Therapy in Long COVID: A Narrative Update Soedarsono, Soedarsono; Wijaya, Rike Andy; Biutifasari, Verna
Jurnal Respirasi Vol. 12 No. 1 (2026): January 2026
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v12-I.1.2026.90-96

Abstract

Introduction: Long coronavirus disease (COVID-19), also known as post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC), is characterized by persistent, often debilitating symptoms that extend beyond the acute phase of COVID-19. These manifestations are associated with immune dysregulation, chronic inflammation, and oxidative stress. Hyperbaric oxygen therapy (HBOT), which involves inhaling 100% oxygen at elevated atmospheric pressure, has emerged as a potential intervention to mitigate these processes. This narrative review synthesized findings from recent clinical and translational studies evaluating the immunological effects of HBOT in patients with long COVID. Methods: A structured search of PubMed, Scopus, and ScienceDirect was conducted for articles published between January 2020 and April 2025 using predefined keywords related to HBOT, long COVID, inflammation, and biomarkers. Seven primary studies met the inclusion criteria and were analyzed for their clinical outcomes and molecular immunomodulatory effects. Results: Evidence indicates that HBOT contributes to significant reductions in pro-inflammatory cytokines, such as interleukin (IL)-6 and tumor necrosis factor-α (TNF-α), while increasing anti-inflammatory cytokines, such as IL-10. Improvements in systemic biomarkers, including C-reactive protein, ferritin, and reactive oxygen species (ROS), have also been observed. In parallel, HBOT has been linked to enhanced mitochondrial function, immune balance, and tissue oxygenation, all of which support recovery from long COVID-related organ dysfunction. Conclusion: Despite promising results, heterogeneity in study design, small sample sizes, and limited long-term follow-up highlighted the need for further rigorous, standardized clinical trials. Overall, HBOT appears to be a biologically plausible and clinically relevant adjunctive therapy for long COVID, with inflammation-related biomarkers serving as correlates or secondary indicators of therapeutic response.
Co-Authors Abd. Rasyid Syamsuri Abimanyu Wahyu P.S.P. Adi Prasetyo Pambudi Adnyana , I Made Dwi Mertha Agustini, Lukisiari Agustiyanto, Catur Ainiyah, Safira Nur Akhiruddin Akhiruddin Amaliah, Lia Ananda, I Gede Yogi Prema Aryanti, Yuni Ashari, Mochamad Hisam Awiyati, Ian Tangguh Bakhtiar, Arief Bambang Hariyanto Bimantara, Firmandhi Sahid Biutifasari, Verna Bur, Eka Yulianti Cho, Yong-Soon Datumarin, Fathia Deby Kusumaningrum Deddy Susanto Endraswari, Pepy Hartanto, Azis Herawati, Fauna Herni Setyawati Imam Wahyudi Indrawan, Imam Wahyudi Indrawanto, Dwi Wahyu Jazim Hamidi Joko Sutrisno Junus, Herisa Nataliana Jusak Nugraha Kartono Wibowo, Kartono Kasih, Shindya Kinasih Prayuni, Kinasih Kusmiati, Tutik Kusmiati, Tutik Kusuma Dewi, Anindya Zalfaa Lisa Fitriyana Lyndia Effendy M. Dikman, Irmawati Mahardika, Vera Makhfudli Makhfudli Mandayani, Sari Mudiyono, Rachmad Muljono, Christa Graziella Nadir Nadir, Nadir Najimuddin, Didin Ni Made Mertaniasih Ni'am, M. Faiqun Nono Carsono Nugroho, Antonius Novan Setyo Nugroho, Eko Pudjo Pangeran Paita Yunus Panuwun, Rizky Tulus Permatasari, Ariani Poedjiastuti, Hermin Pradhana, Agung Pratama A., Ronald Pratiwi Adi, Henny Rachmat Mudiyono, Rachmat RACHMAT RACHMAT Rampengan, Vicky Reinold Christofel Resti Yudhawati Rika Yuliwulandari Ronald Pratama Adiwinoto Rudi Hariyono, Rudi S Imam Wahyudi Safitri, Adam Semedi, Bambang Pudjo Setiawati, Rosy Setyaningsih, Theresia Puji Setyobudi, Nurul Ilmiyati Slamet Imam Wahyudi, Slamet Imam SP Gustami Suhaemi Suhaemi, Suhaemi Sulistyowati, Titiek Syafa'ah, Irmi Syafaat, Muchamad Ali Syafaat, Muchamad Ali TARUNA, DODY Tasalina Yohana Parameswari Gustam UMI FATMAWATI Umiastuti, Pirlina Wajdi*, Bina Arumbinang Wajdi, Bina Arumbinang Wicaksana, Bayu Septiaji Wijaya, Rike Andy Wulandari, Dian Novita Yelvi Levani Yulistiani Yulistiani, Yulistiani