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All Journal MARINA CHIMICA ACTA Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Elkawnie PROSIDING SEMINAR KIMIA Jurnal Industri Hasil Perkebunan Jurnal Kimia Riset Indonesia Chimica Acta Jurnal Penelitian Pendidikan IPA (JPPIPA) Al-Kimia Indonesian Journal of Chemistry Indonesian Journal of Pure and Applied Chemistry Automotive Experiences Journal of Community Health Provision Molekul: Jurnal Ilmiah Kimia Rafflesia Journal of Natural and Applied Sciences (RJNAS) Journal of Biotropical Research and Nature Technology
Nunuk Hariani Soekamto
Department Of Chemistry, Faculty Of Mathematics And Natural Sciences, Hasanuddin University, Perintis Kemerdekaan Street KM 10, Tamalanrea Makasssar, Indonesia.
Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Veterinary

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Journal : MARINA CHIMICA ACTA

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A Preliminary Study of Bioactivity and Identification of Secondary Metabolite Functional Groups in Extracts of Agelas nakamurai Hoshino Sponge from Spermonde Archipelago, Indonesia Ajuk Sapar; Alfian Noor; Nunuk Hariani Soekamto; Tri Aryono Hadi
Marina Chimica Acta Vol. 14 No. 2 (2013): Volume 14 No. 2 (2013)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (358.582 KB) | DOI: 10.20956/mca.v14i2.971

Abstract

Uji pendahuluan bioaktivitas dan identifikasi gugus fungsi metabolit sekunder ekstrak dalam metanol, n-heksan and metilen klorida dari spons Agelas nakamurai Hoshino, asal pulau Kapoposang, kepulauan Spermonde telah dilakukan. Juga test bioaktivitas dilakukan menggunakan Artemia salina (LC50) untuk mendapatkan  konsentrasi letalnya.  Hasilnya  LC50  adalah 187.932  ppm   yang  menunjukkan potensi ekstrak sebagai obat anti kanker. Identifikasi komponen dengan reagensia spesifik seperti Lieberman- Burchard, Mayer, Wagner, Dragendorff dan Salkowski ditambah hasil analisis FTIR menunjukkan kandungan komponen ekstrak seperti alkaloid, steroid and terpenoid. Karakteristik pita serapan alkaloid adalah for alkaloid adalah stretching NH at 3600 to 3400 cm-1 dan stretching pendukung C-N at 1250 to 1930 cm-1. Komponen spesifik untuk Agelas nakamurai adalah substitusi bromo dalam alkaloid yang ditandai oleh munculnya pita serapan  C-Br medium pada 760 to 745 cm-1.
TOXICITY ASSESSMENT ON NINE SPONGES SPECIES FROM SPERMONDE ARCHIPELAGO Ajuk Sapar; Alfian Noor; Nunuk Hariani Soekamto; Ahyar Ahmad; Tri Aryono Hadi
Marina Chimica Acta Vol. 16 No. 2 (2015): Volume 16 No. 2 (2015)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/mca.v16i2.2542

Abstract

Toxicity assessment have been conducted on nine sponges species collected from Spermonde Archipelago namely Kapoposang Island, Samalona Island and Lanjukang Island. Toxicity assessment was using Brine Shrimp lethality Test (BST) method againts sponge extracts. Theresults test were expressed as 50% lethal concentration (LC50) to Artemia salina and correlated with prospecting extract potential as anticancer. All extracts obtained from smallscale extraction by methanol. Test results as follows: Acanthostrongylophora ingens (24.830 μg/mL), Hytios erectus (46.140 μg/mL), Stylissa massa (>1000 μg/mL), Theonella sp (35.010 μg/mL), Niphates olemda (87.500 ppm), Haliclona (Reniera) fascigera (78.160 μg/mL), Petrosia (Petrosia) sp (3.008), Callyspongia (Euplacella) biru (0.515 μg/mL). The test results showed that seven species are potential as anticancer with LC50 value ≤ 500 ppm and only Stylissa massa extracts was not potential as anticancer.
Co-Authors . Asmirah A.A. Ketut Agung Cahyawan W Abdul Karim Abdul Wahid Wahab Ahyar Ahmad Ahyar Ahmad Ajuk Sapar Alfian Noor Alfian Noor Alfian Noor Alfian Noor Alfian Noor Alfian Noor Amalia, Hilda Ayu Melvi Arfah, Rugaiyah A. Artania Adnin Tri Suma Ayun Dwi Astuti Badrawati, Kadek Susi Bahrun Bahrun Beddu Jawahir Erwin Erwin Erwin Erwin Erwin Erwin Felycitae Ekalaya Appa Firdaus Firdaus Firdaus Firdaus Firdaus Firdaus, Firdaus Fitriyanti Jumaetri Sami Fredryk Welliam Mandey Hanapi Usman Harningsih Karim Hasnah Natsir Hasnah Natsir Ihsanul Arief Imran Imran Irmawan, Muhammad Jalifah Latip Kalalinggi, Septaria Yolan Kasturiasih, Ni Putu Khairunnur, Siti Kolo, La La Kalamu, La Yusran La Kolo Labanni, Arniati Maming Maming Marry Garson Muh. Bachri Amran Muhammad Zakir Muhammad Zakir Muhammad Zakir Musa, Bulkis Musrifah Tahar Nasriadi Dali Nursiah La Nafie Nurwijayanti Paulina Taba Payapo Irfa Apriliyanti Rasyid, Herlina Rosmawaty Rosmawaty S Siswanto Sahidin . Samriani Samriani Selfi Wullur Seniwati Dali Sernita, Sernita St. Fauziah St. Fauziah Suriani Nur Syadza Firdausiah Syadza Firdausiah Syahrir, Nur Hilal A. Syarifuddin, Syamsidar Haji Tjodi Harlim Tjodi Harlim Tjodi Harlim Tri Aryono Hadi Tri Aryono Hadi USMAN - Yana Maolana Syah Yusafir Hala Yusuf, Mohammad Taufik Zakaria Zakaria Zakaria