Diana Sunardi
Departemen Ilmu Gizi Fakultas Kedokteran Universitas Indonesia Indonesian Hydration Working Group - FKUI

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The Roles of Carbohydrate-Electrolyte Solutions in Athlete Hydration Status and Performance : A Narrative Review Ervira Wahyuni; Diana Sunardi; Bernie Endyarni Medise
JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA Vol 9, No 1 (2024): Improve physical competence, fitness, motivation, and enjoyment of physical acti
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/jpjo.v9i1.66552

Abstract

Dehydration is prevalent among athletes. Dehydration may cause fluid and electrolyte imbalance and impairment of an athlete physical and cognitive performance. Carbohydrate electrolyte solutions (CES) are often used by athletes as a rehydration fluid because it is claimed to have numerous beneficial effects on hydration status and performance. Studies on the use of carbohydrate-electrolyte solutions showed mixed results. Some studies also highlighted the side effects of carbohydrate-electrolyte solutions on gastrointestinal system. This review aimed to summarize the roles of carbohydrate-electrolyte solutions on hydration status and performance of athletes. The literature review was conducted in the narrative type. Database search was conducted using Pubmed Central search engine. The search terms used were "carbohydrate", "electrolyte", "athlete", "hydration", and "performance". The results show that carbohydrate-electrolyte solutions may prevent dehydration and electrolyte disturbance by increasing water absorptions and retentions. The maintenance of hydration status and the ergogenic effect exerted by carbohydrate can also prevent performance deteriorations. The formulation and administration of carbohydrate-electrolyte solutions must be done with caution and be given at the right timing to reduce side effects, primarily the gastrointestinal discomfort.
Evidence-Based Case Report: Efektivitas Jahe Terhadap Kontrol Glikemik dan Profil Lipid pada Pasien Sindrom Metabolik Nurhayati M Rasyid; Diana Sunardi
Jurnal Sehat Indonesia (JUSINDO) Vol. 6 No. 01 (2024): Jurnal Sehat Indonesia (JUSINDO)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v6i01.82

Abstract

Saat ini, tatalaksana sindrom metabolik (SM) berfokus pada perbaikan parameter metabolik seperti kontrol gula darah dan memperbaiki profil lipid dengan terapi farmakologis. Hal ini menjadi perhatian masyarakat terutama karena penggunaan obat – obatan jangka panjang dan efek samping yang ditimbulkan. Senyawa fitokimia dalam jahe yaitu gingerols dan shogaols memiliki banyak manfaat farmakologis terutama untuk pencegahan dan terapi SM, khususnya penyakit yang ditimbulkan akibat SM seperti diabetes dan penyakit kardiovaskular. Tujuan dari penelitian ini yaitu meneliti apakah jahe dapat memberikan manfaat dalam mengontrol gula darah dan memperbaiki profil lipid pasien SM dibandingkan dengan kondisi tanpa penggunaan jahe. Penelusuran literatur dilakukan di Pubmed®, Cochrane® dan Scopus® pada tanggal 3 Januari 2022 dengan menggunakan advanced search. Dari hasil pencarian melalui 3 database tersebut, dilakukan uji duplikasi dengan menggunakan Covidence. Berdasarkan hasil telaah diatas, efek pemberian suplemen jahe pada pasien sindrom metabolik memberikan hasil yang cukup baik dalam kontrol glikemik dan memperbaiki profil lipid, studi menunjukkan bahwa pemberian suplemen jahe setiap hari dalam waktu lama tidak menyebabkan efek samping yang serius seperti yang sering ditemukan pada pemberian obat oral anti diabetik (OAD) dan obat – obat hiperlipidemia, sehingga pemberian suplemen jahe pada pasien sindrom metabolik aman digunakan jangka panjang dan dapat menjadi pertimbangan.
Efektivitas Suplementasi Vitamin E Terhadap Perbaikan Kadar Enzim Transaminase pada Pasien Non-Alcoholic Fatty Liver Disease Wella Angelia; Diana Sunardi
Jurnal Sehat Indonesia (JUSINDO) Vol. 6 No. 01 (2024): Jurnal Sehat Indonesia (JUSINDO)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v6i01.89

Abstract

Peningkatan stres oksidatif diketahui berkontribusi dalam progresivitas Non-alcoholic fatty liver disease (NAFLD). Oleh karena itu, agen antioksidan dibutuhkan untuk melawan efek tersebut, salah satunya yaitu vitamin E. Efektivitas vitamin E dalam memperbaiki kelainan histologis dan biokimia, termasuk Alanine Transaminase (ALT) dan Aspartate Aminotransferase (AST), pada pasien NAFLD telah banyak diteliti, namun hasilnya masih belum konklusif. Tujuan dari studi ini adalah untuk mengetahui manfaat suplementasi vitamin E pada pasien NAFLD, khususnya terhadap kadar ALT dan AST. Pencarian literatur melalui Pubmed®, Embase®, Cochrane® dan Scopus®. Istilah Mesh dan judul/abstrak disaring berdasarkan kriteria inklusi dan eksklusi. Artikel Randomized Controlled Trials (RCT) dan Systematic Review/Meta-analysis (SR/MA) dari RCT dinilai dan ditinjau secara kritis. Dua dari 3 studi SR/MA serta 1 studi RCT menunjukkan efek signifikan vitamin E terhadap penurunan kadar ALT dan AST, sementara 1 studi SR/MA menunjukkan hasil yang tidak signifikan. Seluruh artikel SR/MA memiliki heterogenitas yang tinggi karena memasukkan studi dengan jumlah subjek yang kecil serta dosis dan durasi intervensi antar studi yang bervariasi. Suplementasi vitamin E dapat memperbaiki kadar ALT dan AST pada pasien NAFLD. Studi lebih lanjut diperlukan untuk menilai dosis efektif suplementasi vitamin E pada NAFLD.
The Effect of Vitamin D Supplementation on Autoimmune Bullous Skin Disorder Intensity Score on Bullous Pemphigoid and Acute Kidney Injury: A Case Report Rahmita, Kartika Soka; Diyah Eka Andayani; Diana Sunardi
Archives of The Medicine and Case Reports Vol. 5 No. 3 (2024): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v5i3.529

Abstract

Introduction: Bullous pemphigoid is the most common bullous-type autoimmune disease. Hypovitaminosis D is often associated with autoimmune disease and found in 86,7% bullous pemphigoid patients. Vitamin D supplementation in bullous pemphigoid patients ought to ameliorate its clinical symptoms. Case presentation: A-58 years old male patient with bullous pemphigoid and acute kidney injury admitted with a chief complaint of infected blisters all over the body. The patient had been treated for 1 week with worsening swallowing pain and low intake. On the 12th day of hospitalization, the patient was given calcitriol supplementation of 0,25 mcg per day. There was an improvement in clinical symptoms shown on autoimmune bullous skin disorder intensity score (ABSIS) from 57 on inpatient day 7 to 17.5 on inpatient day 20. Patient discharged on the 20th day of hospitalization with no emerging blisters and the ability to swallow minced food by mouth. Conclusion: Calcitriol supplementation of 0,25 mcg per day for 10 days helps to improve the ABSIS score in bullous pemphigoid patient with acute kidney injury. Administration of calcitriol is considered safe and well tolerated.
The Effect of Probiotics on Radiation Enteritis in Endometrial Cancer Patients Undergoing Radiotherapy Godong, Bernardine; Ratna Mutumanikam, Nurul; Sunardi, Diana
Archives of The Medicine and Case Reports Vol. 5 No. 3 (2024): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v5i3.551

Abstract

Introduction: Radiation enteritis is damage to the small and large intestines caused by radiation therapy for regional cancer treatment. The incidence is around 90% in patients undergoing radiation in the pelvic and abdominal regions. This study aimed to report the effect of probiotics on radiation enteritis in endometrial cancer patients. Case presentation: A 57-year-old morbidly obese woman diagnosed with endometrial cancer underwent chemoradiation therapy. On the 21st out of 25 radiation sessions and the 2nd chemotherapy session, the patient visited the nutrition clinic at the Radiation Oncology Therapy Center with a complaint of diarrhea for the past 5 days. The diarrhea occurred approximately 10 times a day, with each bowel movement being approximately 50 ml and yellow in color. The patient was then treated with anti-diarrheal therapy, probiotics (Lactobacillus acidophilus, Bifidobacterium longum, and Streptococcus thermophilus) 2 times a day, zinc 20 mg once a day, and prescribed a low-fat and lactose-free diet. After monitoring on the 21st day, the frequency of liquid bowel movements decreased to 2 times a day, and the appetite improved. Conclusion: Patients with radiation enteritis who are given probiotics may experience a reduction in symptoms of acute diarrhea. Direct administration of probiotics increases beneficial bacteria in the digestive tract.
Nutrient intake and stunting in children aged 2-5 years in a slum area of Jakarta Ratnayani, Ratnayani; Sunardi, Diana; Fadilah, Fadilah; Hegar, Badriul
Paediatrica Indonesiana Vol. 64 No. 2 (2024): March 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.2.2024.132-8

Abstract

Background Stunting is one of the problems that occurs in children who live in slum areas. Inadequate nutrient intake has been associated with stunting in children. Objective To assess nutrient intake and analyze the differences between stunted and non-stunted children aged 2-5 years. Methods This comparative cross-sectional study compared nutrient intake and stunting among children 2-5 years in slum areas in Kebon Bawang Village North Jakarta. Subjects’ nutrient intake was assessed using the Semiquantitative-Food Frequency Questionnaire (SQ-FFQ). To analyze differences in subject characteristics and nutrient intake in the stunted and non-stunted groups, Chi-square, Mann-Whitney test, and independent T-test were used. Results From a total of 42 respondents, the characteristics of subjects were not significantly different between the stunted and non-stunted groups, in age (P=0.120), gender (P=0.126), maternal occupation (P=0.729), or maternal education (P=0.127). The stunted group had significantly lower intake of energy (P=0.003), carbohydrates (P=0.024), protein (P=0.005), and fat (P=0.001) than that of the non-stunted group. However, the majority of subjects had protein adequacy above the sufficiency level in both groups (P=0.638), while significantly more subjects in the stunted group had insufficient carbohydrate adequacy than in the non-stunted group (P=0.032). Conclusion Overall, nutrient intake in the stunted group is lower than that of the non-stunted group. Protein adequacy is above sufficient for most subjects in both groups, while the significantly more stunted subjects have insufficient carbohydrate adequacy. In carrying out interventions, it is necessary to consider fulfilling a balance of nutrients, especially macronutrients.
Effect of vitamin D supplementation on lung function in chronic obstructive pulmonary disease patients: An evidence-based case report Kirana, Annisa Nurul; Sunardi, Diana
World Nutrition Journal Vol. 8 No. 1 (2024): WNJ. Volume 08 Issue 1, August 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i1.0002

Abstract

Background: Chronic obstructive pulmonary disease (COPD) is characterized by progressive and persistent airflow obstruction together with an increased chronic inflammatory response, primarily caused by environmental exposure and smoking habit. Vitamin D deficiency is associated with increased rates of exacerbation and hospitalization in COPD patients. Recent studies have indicated a direct correlation between vitamin D deficiency and the severity of COPD, suggesting that acute exacerbation could be prevented with vitamin D supplementation. Some studies propose that correcting the serum vitamin D level may improve the prognosis for COPD patients experiencing respiratory tract infections. Objective: The aim of this study was to determine the effect of vitamin D supplementation for lung function in COPD patient. Methods: Literature search was carried out by advanced searching on Pubmed, Cochrane Library, and Scopus using a combination of MeSH Terms and Title/Abstract. Following screening for duplications, the literature obtained then screened according to predetermined eligibility criteria. The appropriate literatures were critically reviewed and the level of evidence in accordance with the Oxford Center for Evidence Based Medicine. Results: One meta-analysis and three randomized controlled trial (RCT) met the PICO and eligibility criteria that had been set. Three studies concluded that vitamin D supplementation enhanced lung function in COPD patient. Vitamin D deficiency is common in COPD patients, so it is recommended to check vitamin D levels before vitamin D supplementation. Conclusion: Vitamin D administration can improve lung function and prevent acute exacerbation in COPD patients.
Sarkopenia sebagai Faktor Risiko Varises Esofagus Risiko Tinggi berdasarkan Stratifikasi Child-Pugh Pasien Sirosis Hati Sepmeitutu, Iwandheny; Kurniawan, Juferdy; Maulahela, Hasan; Rinaldi, Ikhwan; Shatri, Hamzah; Pramana, Triyanta Yuli; Makmun, Dadang; Lesmana, Cosmas Rinaldi A; Hidayat, Rudy; Laksmi, Purwita Wijaya; Sunardi, Diana
Jurnal Penyakit Dalam Indonesia Vol. 11, No. 3
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background The high prevalence of sarcopenia in chronic liver disease negatively impacts the quality of life and increases the risk of various complications of cirrhosis, one of which is the development of esophageal varices. The aim of this study was to determine the prevalence of sarcopenia in cirrhosis patients based on the severity of liver cirrhosis and to explore the association of sarcopenia with high-risk esophageal varices stratified by Child-Pugh. Methods This observational cross-sectional study involved patients with liver cirrhosis at Cipto Mangunkusumo Hospital between January and September 2023. Sarcopenia was defined as a reduction in muscle mass accompanied by decreased grip strength or walking speed, according to the AWGS 2019 criteria (Asian Working Group for Sarcopenia). Multivariate logistic regression analysis was conducted to evaluate the association between sarcopenia and high-risk esophageal varices. Results A total of 155 patients with liver cirrhosis were included in this study. The majority of liver cirrhosis patients were males, with hepatitis B being the most commonly found etiology. The prevalence of sarcopenia was found in 40.0% of Child-Pugh A patients, 53.8% of Child-Pugh B patients, and 50.0% of Child-Pugh C patients with a p-value of 0.411. The high-risk of esophageal varices was found more frequently in Child-Pugh B (53.8%) and Child-Pugh C (50.0%) compared to Child-Pugh A (25.6%) with a p-value of 0.013. Bivariate analysis showed that the presence of sarcopenia in liver cirrhosis patients has a statistically significant association with an increased risk of high-risk esophageal varices, especially in the Child-Pugh B and C subgroups of liver cirrhosis patients (OR = 7.50 (95% CI: 1.48 – 37.91, p<0.030)). However, no association was found between sarcopenia and high-risk esophageal varices in the Child-Pugh A subgroup (OR = 1.46 (95% CI: 0.65 – 3.29, p<0.477)). Conclusion Sarcopenia significantly increases the risk of high-risk esophageal varices in liver cirrhosis, especially in those with Child-Pugh B and C classification.
Effect of Vitamin D3 on Changes in Muscle Mass in the Elderly in Nursing Homes: Double-Blind Controlled Randomized Trial Prajna Adhityarani; Diana Sunardi; Esthika Dewiasty
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 6, No 1 (2024): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v6i1.19030

Abstract

The decline in muscle mass and strength begins at the age of 30 years by 40% within 30 years, then will decrease by 40% every ten years after the age of 60 years. Loss of muscle mass and strength in older people causes weakness and reduced muscle function, which can lead to a decrease in the ability to perform activities of daily living and an increased risk of falls. In addition, older people are prone to malnutrition; this condition will be accompanied by micronutrient deficiencies both in older people who are undernourished and overnourished. Giving vitamin D3 to increase muscle mass and ability and reduce fat mass in older people also has pros and cons. So, this study aims to explore the effect of giving Vitamin D3 on changes in muscle mass in older adults. The study will also examine changes in upper arm muscle strength and evaluate the impact of Vitamin D3 on changes in muscle mass. This research is a study with an Experimental Randomised Control Trial (RCT) research design. The population was elderly who were deficient in vitamin D, while the study sample amounted to 26 control subjects and 26 action subjects. Samples are taken by consecutive sampling technique. Based on research findings, most older adults (60-69 years) suffer from vitamin D deficiency and deficiency. However, vitamin D3 supplementation increases the muscle mass of older adults in nursing homes, especially in the muscles of the upper and lower extremities. However, the supplement weakens muscle mass and causes bruising and bleeding but does not weaken arm muscle mass. Keywords: Elderly, Muscle Mass, Panti Werdha, Vitamin D3
Optimizing nutrients intake of children in Indonesia: Dietary modelling approach Sunardi, Diana; Wibowo, Yulianti
World Nutrition Journal Vol. 8 No. S1 (2024): Selected conference proceedings of the Nutri Symposium 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.S1.0012

Abstract

The prevalence of obesity is rising in high-income countries, while low-income populations face the triple burden of malnutrition. Improving dietary intake is crucial in addressing these issues. Diet optimization or diet modelling have emerged as valuable tools for identifying the optimal combination of foods that meet daily nutritional requirements by incorporating nutrient-dense options into the diet.
Co-Authors Achmad Mulawarman Jayusman Afifa, Nadhira Nuraini Ali Sungkar Ali Sungkar Almira Devina Anak Agung Eka Widya Saraswati Andry Kelvianto Angelia, Wella Anin Ika Rosa Ardesy Melizah Kurniati arieska felicia Audy Alexander, Ruth Ayu Andin Wardani, Mutia Ayu Diandra Sari Ayu Diandra Sari Badriul Hegar Bernie Endyarni Medise Budi Wiweko C Rinaldi A Lesmana Chandra, Dian Novita Christy, Sarah claresta diella Dadang Makmun Devina, Almira Dewi Friska Dian Araminta Ramadhania Dian Araminta Ramadhania Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Diyah Eka Andayani Diyah Eka Andayani Diyah Eka Andayani Dwi Nastiti Iswarawanti Dyah Arum Kusumaningtyas E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Erfi Prafiantini Ervira Wahyuni Esthika Dewiasty Esthika Dewiasty Esthika Dewiasty Evania Astella Setiawan Evania Astella Setiawan Fadilah Fadilah, Fadilah Ferdi, Jessica Fransisca Olivia Gabriella Nurahmani Putri Gloriana Seran Godong, Bernardine Handayani Eka Puspita Sari Hasan Maulahela Helda Khusun Ikhwan Rinaldi Iwan Surjadi Handoko Juferdy Kurniawan Karin Wiradarma Kirana, Annisa Nurul Krisadelfa Sutanto Krisadelfa Sutanto Luana Lidwina Maggie Nathania Marvin Marino Melyarna Putri Mulianah Daya Muningtya Philiyanisa Alam Neng Tine Kartinah Almuktabar Ninik Mudjihartini Noorwati Sutandyo Novi Silvia Hardiany Nurhayati M Rasyid Nurul Ratna Manikam Nurul Ratna Mutu Manikam Patricia Amanda Pauline Octaviani Prajna Adhityarani Purwita Wijaya Laksmi Putri Novia Choiri Insani Rahmita, Kartika Soka Raphael Kosasih Rasyid, Nurhayati M Ratnayani Reisa Melisa Wijaya Rini Sekartini Rizki Yusrini Pohan Rudy Hidayat Ruth Audy Alexander Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Sepmeitutu, Iwandheny Sheena R. Angelia Stefani, Shiela Steffi Sonia Surjadi Handoko, Iwan Tiara Aninditha Titis Prawitasari, Titis Triyanta Yuli Pramana Wella Angelia Wicaksari, Sifa Aulia Wiji Lestari Wiji Lestari Winarsa, Jessica Witjaksono, Firisha Virgidewi Yosua Y Kristian Yosua Yan Kristian Yulhasri Yulhasri Yulianti Wibowo, Yulianti