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All Journal Jurnal Gizi dan Pangan Sari Pediatri Paediatrica Indonesiana JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA AcTion: Aceh Nutrition Journal Contagion: Scientific Periodical Journal of Public Health and Coastal Health Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia World Nutrition Journal Jurnal Prima Medika Sains Journal of Community Empowerment for Health IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) Archives of The Medicine and Case Reports Cermin Dunia Kedokteran Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Sehat Indonesia (JUSINDO) Jurnal Penyakit Dalam Indonesia Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute Cermin Dunia Kedokteran
Diana Sunardi
Departemen Ilmu Gizi Fakultas Kedokteran Universitas Indonesia Indonesian Hydration Working Group - FKUI
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Peran Pemeriksaan Malondialdehid sebagai Penanda Stres Oksidatif pada Anak Stunting: Tinjauan Sistematik Tarigan, Ananda Putri; Gunarti, Dwirini Retno; Sunardi, Diana
Majalah Kedokteran Indonesia Vol 74 No 4 (2024): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.74.4-2024-1256

Abstract

Introduction: Stunting is a form of chronic malnutrition which is still a nutritional problem in Indonesia. Stunting is characterized by a decrease in insulin-like growth factor-1, closely related to the release of excess reactive oxygen species that trigger oxidative stress. An increase in reactive oxygen species that bind to membrane lipids produces lipid peroxidase, which impacts cell damage. The research aims to obtain information regarding the role of malondialdehyde measurement as an early marker and a prognostic determinant of oxidative stress in protein-energy malnutrition children, such as stunted and marasmic.Method: Systematic literature was conducted with published works journal searches from 23rd – 30th November 2023, relevant keywords related to the research topic in ScienceDirect, PubMed, and Cochrane databases using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis 2020 method. The quality of selected studies was evaluated using The Joanna Briggs Institute Critical Appraisal Tools. The research protocol was registered at PROSPERO (CRD42024568540).Results: The data obtained were five articles from cross-sectional studies with the results had increased oxidative stress biomarkers, including malondialdehyde, which is significantly higher in protein-energy malnutrition children, such as stunted and marasmic, than in healthy children (p less than 0.05).Conclusion: The malondialdehyde levels as biomarkers of oxidative stress were found to be high in stunted children.
Pengaruh Pemberian Probiotik terhadap Penurunan Gejala Enteritis pada Pasien Karsinoma Sel Skuamosa Serviks dalam Terapi Radiasi: studi kasus dengan pendekatan berbasis bukti Witjaksono, Firisha Virgidewi; Sunardi, Diana
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 1 (2025): Maret 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i1.1493

Abstract

Latar Belakang: Kanker serviks adalah salah satu jenis kanker yang paling umum pada wanita di negara berkembang. Radioterapi merupakan salah satu terapi utama, namun dapat menyebabkan efek samping, salah satunya adalah enteritis terkait radiasi. Probiotik diketahui dapat membantu mengurangi gejala enteritis terkait radiasi dengan memperbaiki keseimbangan mikrobiota usus dan mengurangi peradangan. Hasil penelitian yang beragam dan belum konklusif mendorong perlunya penelitian lebih lanjut untuk mengevaluasi efektivitas probiotik dalam mengurangi gejala enteritis pada pasien karsinoma sel skuamosa serviks. Objektif: Mengetahui efek pemberian probiotik terhadap penurunan gejala enteritis terkait radiasi pada pasien karsinoma sel skuamosa serviks. Metode: Penelusuran literatur dilakukan pada empat pangkalan data, yaitu PubMed, Cochrane, dan Embase, menggunakan kata kunci MeSH terms. Penyeleksian artikel dilakukan dengan penapisan judul atau abstrak, telaah teks lengkap, dan menentukan terpenuhinya kriteria inklusi dan eksklusi. Dilakukan telaah kritis pada dua studi kajian literatur sistemik/meta-analisis dari uji acak terkontrol berdasarkan telaah validity, importance, dan applicability. Hasil: Tiga literatur dipilih secara kritis. Artikel pertama menunjukkan bahwa tidak ada pengurangan RID yang signifikan secara statistik (RR = 0,52, 95% CI = 0,14, 1,91) yang diamati pada analisis subkelompok pada pasien yang menerima terapi radiasi dan kemoterapi. Namun, pasien yang hanya menerima terapi radiasi menunjukkan manfaat yang signifikan (RR = 0,61, 95% CI = 0,48, 0,78). Artikel kedua menunjukkan bahwa jumlah rata-rata tinja cair dengan Bristol tipe 6 dan 7 tidak berkurang secara signifikan dalam kelompok probiotik, namun terdapat pengurangan yang signifikan pada kelompok yang jumlah rata-rata buang air besar dengan lebih dari 1 kali tinja cair yaitu 15,04 ± 8,92 hari dalam plasebo dan 8,65 ± 5,93 hari dalam kelompok probiotik dosis tinggi (P = 0,014). Artikel ketiga menunjukkan bahwa insiden diare berkurang pada kelompok probiotik dibandingkan kelompok plasebo (53,8 dan 82,1%, p < 0,05). Diare ringan hingga sedang dan berat berkurang secara signifikan pada kelompok probiotik (p < 0,05). Kesimpulan: Pemberian probiotik dapat menurunkan gejala RID pada pasien kanker serviks.
Asupan Serat Pangan dan Hubungannya dengan Keluhan Konstipasi pada Kelompok Dewasa Muda di Indonesia Saptawati Bardosono; Iwan Surjadi Handoko; Ruth Audy Alexander; Diana Sunardi; Almira Devina
Cermin Dunia Kedokteran Vol 47 No 10 (2020): Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i10.553

Abstract

Walaupun sampai saat ini konstipasi fungsional masih beragam definisinya, gejalanya sering dikeluhkan karena dirasakan mengganggu kualitas hidup khususnya, pada kelompok dewasa muda, dan bila tidak ditangani dengan baik akan berdampak negatif bagi kesehatan. Asupan serat yang memadai merupakan salah satu alternatif yang efektif untuk mengatasi masalah tersebut, namun asupan sayur dan buah masyarakat di Indonesia masih jauh dari angka kecukupan yang dianjurkan; jumlah asupan serat harian pekerja dewasa muda di Jakarta bervariasi antara 3,3-27,4 g. Tambahan serat pangan dalam diet sehari-hari diharapkan dapat meningkatkan asupan serat sehingga dapat bermanfaat untuk mengatasi keluhan konstipasi. Although until now functional constipation still has various definitions, the symptoms are often interfering with quality of life, especially in young adults. If not managed properly, it may have a serious negative impact on health. Adequate fiber intake is an effective alternative to overcome this problem, but vegetables and fruits intake in Indonesia is still far from adequate. A recent pilot study found that the daily fiber intake among young adult workers in Jakarta is varied between 3.3–27.4 g. Additional dietary fiber in daily diet is expected to increase fiber intake so that it can be useful for dealing with complaints of constipation.
Hubungan Antara Asupan Energi dengan Rasio Neutrofil Limfosit pada Pasien Sakit Kritis Purwantini, Dian; Wulandari, Yohannessa; Sunardi, Diana; Sutanto, Krisadelfa; Sinaga, Wina; Andayani, Diyah Eka
Majalah Kedokteran Indonesia Vol 75 No 2 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.2-2025-1760

Abstract

Introduction: Critically-ill patients experience catabolic stress and inflammatory responses resulting in increased catabolism to meet energy demands. Neutrophil lymphocyte ratio (NLR) is used to assess immune and stress responses. Method: This study was a cross-sectional study of subjects aged ≥18 years admitted to the intensive care unit of Dr. Cipto Mangunkusumo National Central General Hospital and University of Indonesia Hospital. The characteristics of the study subjects included age, gender, nutritional status, diagnosis of ICU admission, protein intake, fat intake, and carbohydrate intake. Bivariate analysis was performed to evaluate the correlation between energy intake and neutrophil-lymphocyte ratio.Result: There were 44 subjects with a median age of 55 years (19-86). Nutritional status based on body mass index (BMI) obtained 31.8% normal nutritional status, 20.5% severe malnutrition, 25% obesity grade 1. The most common diagnoses were surgery and trauma 20.5% of subjects and sepsis 20.5% of subjects. Median RNL was 10.39 (2.51-59.5), energy intake was 10.5 (3-29) kcal/kg BW/day, protein intake was 0.4 (0-1.2) g/kg BW/day, fat intake was 18 (0-29)% and carbohydrate intake was 92 (23-184) g/day.Conclusion: There was no correlation between energy intake and NLR.
Optimizing nutritional status with nutritional therapy in malnourished patient post whipple’s procedure: A case report Stefani, Shiela; Sunardi, Diana; Sonia, Steffi
Jurnal Prima Medika Sains Vol. 7 No. 1 (2025): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v7i1.6235

Abstract

The prevalence of malnutrition is considerably high among patients with pancreatic cancer and that Whipple procedure is associated with high morbidity and mortality rates. Post-Whipple procedure nutritional therapy can help to preserve nutritional status, accelerate recovery of functional capacity, and improve patient’s quality of life. A 65-year-old malnourished woman underwent Whipple procedure for adenocarcinoma of ampulla of Vater. Oral pre-operative nutrition was given in the form of normal food and oral nutritional supplement (ONS). Eight hours before surgery, the patient received ONS containing 30 g carbohydrate. The patient was given early enteral nutrition at <48 hours post-operatively and was given oral nutrition as soon as she regained consciousness. The patient experienced post-operative pancreatic fistula (POPF) grade A. Post-operative in-hospital and homecare nutritional therapy included supply of energy, macronutrients, micronutrients, and nutritional education adjusted to the patient’s clinical condition and intake tolerance. Energy intake during hospitalization attained 109% of the estimated total energy requirement that consisted of up to 1.9 g/kg/day protein. Homecare nutritional intake reached almost 2 times basal energy requirement with 2.2 g/kg/day protein intake. The patient experienced improvement of clinical symptoms, POPF, intake tolerance, glycemic control, and functional capacity. The patient was allowed to be discharged and treated in the outpatient clinic, without readmission in the next 2 months. Adequate hospital and homecare medical nutritional therapy in post-Whipple procedure may improve nutritional status and functional capacity, improve clinical outcome, and prevent readmission of patients.
The role of nutritional management in preventing stroke and improving clinical outcomes Mauluddy, Anggita Citra Resmi; Sunardi, Diana
World Nutrition Journal Vol. 9 No. i1 (2025): Volume 09 Issue 1, August 2025
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V09.i1.0002

Abstract

Background: Stroke is a leading cause of global morbidity, mortality, and substantial economic burden. Modifiable stroke risk factors, including hypertension, dyslipidemia, obesity, and diabetes mellitus, can be effectively managed through targeted nutritional interventions. Nutritional management also supports neurological recovery and contributes to improved clinical outcomes in stroke survivors. Methods: A literature review was conducted using PubMed, MEDLINE, and EMBASE databases from the last ten years, focusing on nutritional management for stroke prevention, clinical outcomes, dietary patterns, and nutrient supplementation during post-stroke recovery. Results: Dietary strategies, including Dietary Approaches to Stop Hypertension (DASH), high intake of dietary fiber, and omega-3 fatty acids, significantly reduce stroke risk by improving cardiovascular health and decreasing inflammation. Supplementation with micronutrients such as B vitamins supports neurological and vascular function. Post-stroke nutritional issues such as dysphagia, malnutrition, sarcopenia, and pressure injuries commonly impair patient recovery. Targeted nutritional intervention, particularly adequate protein and branched-chain amino acid (BCAA) supplementation, help preserve muscle mass, enhance functional recovery, and optimize rehabilitation outcomes. Conclusions: Nutritional management plays a crucial role in both preventing stroke and improving clinical outcomes following stroke. Implementing effective nutritional strategies, together with patient education on healthy dietary practices, is fundamental for reducing stroke risk, accelerating recovery, and enhancing quality of life.
Advancing child health through safe hydration Sunardi, Diana
World Nutrition Journal Vol. 9 No. S1 (2025): Vol. 9 No. S1 (2025): Selected conference proceedings of the Nutri Symposium 2
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V09.S1.0009

Abstract

Diarrhea is One in five children in Indonesia does not drink enough water, but that’s not the only problem regarding child health and water consumption. The prevalence of Diarrhea in Indonesian children is one in four children under 5 years old. The high prevalence is closely linked to poor sanitation and unsafe drinking water. Water comprises 75% body weight in infants to 55% in the elderly, and plays very crucial role in cellular hemostasis and life. Therefore, the optimal functioning of our body requires a good hydration level from safe drinking water.
Co-Authors Achmad Mulawarman Jayusman Adelina Haryono Afifa, Nadhira Nuraini Ali Sungkar Ali Sungkar Almira Devina Anak Agung Eka Widya Saraswati Andayani, Diyah Eka Andry Kelvianto Anin Ika Rosa Ardesy Melizah Kurniati arieska felicia Audy Alexander, Ruth Ayu Diandra Sari Ayu Diandra Sari Badriul Hegar Bernie Endyarni Medise Budi Wiweko Budiati Sutanto, Luciana C Rinaldi A Lesmana Chandra, Dian Novita claresta diella Dadang Makmun Devina, Almira Dewi Friska Dian Araminta Ramadhania Dian Araminta Ramadhania Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Diyah Eka Andayani Diyah Eka Andayani Diyah Eka Andayani Dwi Nastiti Iswarawanti Dwirini Retno Gunarti Dyah Arum Kusumaningtyas E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Erfi Prafiantini Ervira Wahyuni Esthika Dewiasty Esthika Dewiasty Esthika Dewiasty Evania Astella Setiawan Evania Astella Setiawan Fadilah Fadilah, Fadilah Fransisca Olivia Gabriella Nurahmani Putri Gloriana Seran Godong, Bernardine Handayani Eka Puspita Sari Hasan Maulahela, Hasan Helda Khusun Ikhwan Rinaldi Iwan Surjadi Handoko Jessica Ferdi Juferdy Kurniawan Karin Wiradarma Khusun, Helda Kirana, Annisa Nurul Krisadelfa Sutanto Krisadelfa Sutanto Luana Lidwina Maggie Nathania Marvin Marino Mauluddy, Anggita Citra Resmi Melyarna Putri Mulianah Daya Muningtya Philiyanisa Alam Neng Tine Kartinah Almuktabar Ninik Mudjihartini Noorwati Sutandyo Novi Silvia Hardiany Nurhayati M Rasyid Nurul Ratna Manikam Nurul Ratna Mutu Manikam Patricia Amanda Pauline Octaviani Prajna Adhityarani Purwantini, Dian Purwita Wijaya Laksmi Putri Novia Choiri Insani Rachmawati, Dessy Suci Rahmita, Kartika Soka Raphael Kosasih Rasyid, Nurhayati M Ratih, Mia Puspita Ratnayani Reisa Melisa Wijaya Rini Sekartini Rizki Yusrini Pohan Rudy Hidayat Ruth Audy Alexander Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Sarah Christy Sepmeitutu, Iwandheny Shabrina, Arifah Sheena R. Angelia Sifa Aulia Wicaksari Stefani, Shiela Steffi Sonia Surjadi Handoko, Iwan Sutanto, Krisadelfa Tarigan, Ananda Putri Tiara Aninditha Titis Prawitasari, Titis Triyanta Yuli Pramana Wella Angelia Wiji Lestari Wiji Lestari Wina Sinaga Wina Sinaga Witjaksono, Firisha Virgidewi Wulandari, Yohannessa Yosua Y Kristian Yosua Yan Kristian Yulhasri Yulhasri Yulianti Wibowo, Yulianti