Diana Sunardi
Departemen Ilmu Gizi Fakultas Kedokteran Universitas Indonesia Indonesian Hydration Working Group - FKUI

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Soy Plant-based Formula with Fiber: From Protein Source to Functional Food Bardosono, Saptawati; Sunardi, Diana
World Nutrition Journal Vol. 4 No. S1 (2020): Special Issue : Soy Plant-based and Fiber in Children’s Gut Health, Growth & D
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.S1.0004

Abstract

Several factors are fundamental to support child growth and development, including nutrition. Beside Energy, protein is the key of balanced dietary macronutrients intake as the building block of child growth.  While several micronutrients, i.e. calcium, iron, zinc and vitamins are needed for both optimal growth and development. Among protein-rich foods for young children, cow’s milk formula has several limitations, i.e. cow’s milk allergy and low fiber content. Although has a low bioavailability for iron absorption, plant-rich protein can be an alternative for young children to be used, i.e. as a soy isolate protein formula. However, to the fact of low fiber content in soy isolate protein formula, it is then need further consideration to have a fiber enrichment. We highlight the fiber content in child formula to the extent of its benefit for gastrointestinal health in relation to gut movement in preventing constipation, or its role as a functional food with its prebiotics capacity. This article aims to review a suitable type of fiber used for the enrichment for a soy isolate protein formula.
Efek Suplementasi Vitamin D pada Kadar Hemoglobin Pasien Hemodialisis: Laporan Kasus Berbasis Bukti: Laporan Kasus Berbasis Bukti Winarsa, Jessica; Sunardi, Diana
Cermin Dunia Kedokteran Vol 53 No 03 (2026): Maret 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i03.2016

Abstract

Introduction: Anemia is a common complication of end-stage chronic kidney disease (CKD), particularly in patients undergoing hemodialysis. Vitamin D, a micronutrient with receptors in various cell types, plays a role in enhancing erythropoiesis by promoting the proliferation of erythroid progenitor cells, reducing proinflammatory cytokines and hepcidin, thereby increasing iron bioavailability for hemoglobin (Hb) synthesis. This study aims to investigate the effect of vitamin D supplementation on Hb levels in chronic hemodialysis patients. Methods: A systematic literature search was conducted across 4 databases: PubMed, ProQuest, Cochrane, and Scopus. Inclusion criteria were studies on adult patients undergoing chronic hemodialysis with anemia and with any vitamin D status, published within the last 5 years, and consisting of systematic reviews and meta-analyses (SR-MA) of randomized controlled trials (RCTs) or RCTs. Critical appraisal was performed using the validity, importance, and applicability (VIA) framework from the Oxford Centre for Evidence-Based Medicine (OCEBM). Results: Two RCTs and one SR-MA were critically appraised. Vitamin D supplementation was found to improve Hb levels in chronic hemodialysis patients, with statistically significant effects observed in longer supplementation durations. Conclusion: Vitamin D supplementation in chronic hemodialysis patients has shown promising results in improving Hb levels. Further research is required to determine the optimal type, dosage,and duration of vitamin D supplementation.
Effectiveness of Oral Magnesium in Chronic and Episodic Migraine: An Evidence-Based Case Review Ayu Andin Wardani, Mutia; Sunardi, Diana
Jurnal Ilmu Kesehatan Indonesia Vol. 7 No. 1 (2026): Maret 2026
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v7i1.1790

Abstract

Background: Chronic migraine (≥15 headache days per month) and episodic migraine (<15 headache days per month) are disabling neurological disorders affecting more than one billion people worldwide. Conventional prophylactic therapies, including beta blockers and antiepileptics, may be effective but are often associated with tolerability concerns. Magnesium, an essential mineral involved in vascular regulation and neuronal function, has been proposed as a safe and low-cost alternative for migraine prevention. Objective: To evaluate the effectiveness of oral magnesium supplementation in reducing migraine frequency and intensity through an evidence-based case review. Methods: A systematic literature search was conducted in PubMed, Scopus, Cochrane Central, and Google Scholar. Randomized controlled trials and systematic reviews comparing oral magnesium with placebo or standard prophylactic therapy were included. Results: Seven studies (three randomized controlled trials and four systematic reviews) were identified. Overall, oral magnesium reduced migraine frequency and pain severity, although substantial heterogeneity in formulation, dosage, and study design was observed. Conclusion: Oral magnesium appears safe, inexpensive, and well tolerated, but further high-quality trials are needed to determine optimal dosing and comparative efficacy.
Hidden Threat During Quarantine and Transition Phase in Elderly: The Need for Special Precautions Maggie Nathania; Diana Sunardi
Majalah Kedokteran Indonesia Vol 70 No 10 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, V
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.10-2020-292

Abstract

A global pandemic, COVID-19, has struck 216 countries with more than 9 million cases and 420.000 deaths. In Indonesia alone, 49.000 people have been infected with more than 2.000 deaths. To reduce the transmission rate and break the chain of transmission, various countries in the world require people to limit and mitigate activities outside the house, especially for high-risk groups: the elderly and groups with comorbidities. Although there is no age group protected from SARS-CoV-2 infection, the elderly group shows significantly higher mortality and severity of the disease when compared with young and middle age. Case fatality rate in the elderly ranges between 8% in patients aged ≥80 years, 8% in patients aged 70-79 years, and up to 49% in critical cases. Other studies also show that the average age of patients who need the intensive care unit (ICU) is older than patients who do not require ICU.
Effect of omega-3 supplementation on osteoarthritis: An evidence-based case report Ferdi, Jessica; Diana Sunardi
World Nutrition Journal Vol. 7 No. 2 (2024): WNJ. Volume 07 Issue 2, February 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V07.i2.0003

Abstract

Background: Osteoarthritis is marked by mild inflammation, causing cartilage damage that leads to bone remodelling and potentially reduces the quality of life. Omega-3 has anti-inflammatory properties, which can help mitigate cartilage damage. Objective: This research aims to determine the role of omega-3 in relieving pain in patients with osteoarthritis. Methods: A literature search was conducted using advanced searching on three large databases: PubMed, Cochrane, and Scopus. The search used Mesh terms according to the criteria. After assessing the relevance and suitability of the literature, two articles were selected and critically evaluated based on Oxford Center for Evidence-Based Medicine. Results: Two systematic review-meta-analyses that meet the PICO and eligibility criteria were found. One of the literature sources does not demonstrate the effect of omega-3 supplementation on joint pain, while the other literature source shows the beneficial effects of omega-3 in reducing joint pain in osteoarthritis. Conclusion: Omega-3 supplementation can alleviate joint pain in individuals with osteoarthritis. Providing omega-3 may be worth considering.
Co-Authors Achmad Mulawarman Jayusman Afifa, Nadhira Nuraini Ali Sungkar Ali Sungkar Almira Devina Anak Agung Eka Widya Saraswati Andry Kelvianto Angelia, Wella Anin Ika Rosa Ardesy Melizah Kurniati arieska felicia Audy Alexander, Ruth Ayu Andin Wardani, Mutia Ayu Diandra Sari Ayu Diandra Sari Badriul Hegar Bernie Endyarni Medise Budi Wiweko C Rinaldi A Lesmana Chandra, Dian Novita Christy, Sarah claresta diella Dadang Makmun Devina, Almira Dewi Friska Dian Araminta Ramadhania Dian Araminta Ramadhania Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Diyah Eka Andayani Diyah Eka Andayani Diyah Eka Andayani Dwi Nastiti Iswarawanti Dyah Arum Kusumaningtyas E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Erfi Prafiantini Ervira Wahyuni Esthika Dewiasty Esthika Dewiasty Esthika Dewiasty Evania Astella Setiawan Evania Astella Setiawan Fadilah Fadilah, Fadilah Ferdi, Jessica Fransisca Olivia Gabriella Nurahmani Putri Gloriana Seran Godong, Bernardine Handayani Eka Puspita Sari Hasan Maulahela Helda Khusun Ikhwan Rinaldi Iwan Surjadi Handoko Juferdy Kurniawan Karin Wiradarma Kirana, Annisa Nurul Krisadelfa Sutanto Luana Lidwina Maggie Nathania Marvin Marino Melyarna Putri Mulianah Daya Muningtya Philiyanisa Alam Neng Tine Kartinah Almuktabar Ninik Mudjihartini Noorwati Sutandyo Novi Silvia Hardiany Nurhayati M Rasyid Nurul Ratna Manikam Nurul Ratna Mutu Manikam Patricia Amanda Pauline Octaviani Prajna Adhityarani Purwita Wijaya Laksmi Putri Novia Choiri Insani Rahmita, Kartika Soka Raphael Kosasih Rasyid, Nurhayati M Ratnayani Reisa Melisa Wijaya Rini Sekartini Rizki Yusrini Pohan Rudy Hidayat Ruth Audy Alexander Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Sepmeitutu, Iwandheny Sheena R. Angelia Stefani, Shiela Steffi Sonia Surjadi Handoko, Iwan Tiara Aninditha Titis Prawitasari, Titis Triyanta Yuli Pramana Wella Angelia Wicaksari, Sifa Aulia Wiji Lestari Wiji Lestari Winarsa, Jessica Witjaksono, Firisha Virgidewi Yosua Y Kristian Yosua Yan Kristian Yulhasri Yulhasri Yulianti Wibowo, Yulianti