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All Journal VALENSI Farmaka Majalah Obat Tradisional KOVALEN: Jurnal Riset Kimia Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Penelitian Pendidikan IPA (JPPIPA) Pharmacology and Clinical Pharmacy Research Jurnal Pengabdian kepada Masyarakat Nusantara Jurnal Mandala Pengabdian Masyarakat Jurnal Abdi Masyarakat Indonesia JIFI (Jurnal Ilmiah Farmasi Imelda) Jurnal Abdi Masyarakat Multidisiplin Nanggroe: Journal Of Scholarly Service Journal of Pharmaceutical and Sciences. Nanggroe: Journal of Scholarly Service VIDHEAS: Jurnal Nasional Abdimas Multidisiplin Jurnal Malikussaleh Mengabdi Jurnal Sains dan Kesehatan Taawun: Jurnal Pengabdian kepada Masyarakat
Recky Patala
Program Studi Farmasi, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Universitas Tadulako, Kota Palu, Sulawesi Tengah, Indonesia.
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Edukasi Manfaat Daun Jeruk Nipis Untuk Kesehatan Bagi Masyarakat Desa Sejahtera Kecamatan Palolo, Kabupaten Sigi Yanuarty, Rezky; Patala, Recky; Awilia, Nurkhaliza
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 5 No. 1 (2024): Jurnal Pengabdian kepada Masyarakat Nusantara (JPkMN)
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55338/jpkmn.v5i1.2673

Abstract

Daun jeruk nipis (Citrus aurantifolia) merupakan salah jenis tumbuhan obat yang telah lama digunakan oleh masyarakat lokal di Indonesia. Selain digunakan sebagai obat tradisional, buahnya juga digunakan untuk berbagai bahan makanan atau minuman. Pemanfaatan tumbuhan sebagai obat tradisional berhubungan dengan bioaktivitas dan kandungan metabolit sekundernya. Daun jeruk nipis mengandung senyawa kimia minyak atsiri, flavonoid, saponin, dan terpen yang aktif sebagai racun kontak dan racun perut bagi nyamuk. Selanjutnya Citrus aurantifolia diidentifikasi mengandung Limonoida, yaitu asam limonexat, asam isolimonexat, dan limonin. Senyawa flavonoid memiliki sifat antioksidan yang berperan sebagai penangkap radikal bebas karena mengandung gugus hidroksil. Kegiatan Pengabdian kepada Masyarakat ini bertujuan untuk memberikan edukasi tentang manfaat daun jeruk nipis untuk kesehatan masyarakat di Desa Sejahtera, Kecamatan Palolo, Kabupaten Sigi, Sulawesi Tengah. Kegiatan Pengabdian kepada Masyarakat ini dilakukan dengan dilakukan dalam bentuk sosialisasi dan edukasi dengan menggunakan metode ceramah, diskusi dan membagikan brosur. Hasil kegiatan pengabdian masyarakat ini menunjukkan adanya peningkatan pengetahuan dan pemahaman serta perilaku yang baik terhadap pemanfaatan daun jeruk untuk menangani masalah kesehatan di Desa Sejahtera. Kegiatan ini juga dapat dijadikan sebagai upaya dalam mengatasi masalah kesehatan dengan menggunakan obat-obatan yang dapat dikonsumsi tanpa pengawasan dari dokter.
Komplikasi dan Pencegahan Kolesterol di Desa Lampo, Kecamatan Banawa Tengah, Kabupaten Donggala, Sulawesi Tengah Patala, Recky; M, Mariyani; A, Faidil Afdal
Jurnal Malikussaleh Mengabdi Vol. 2 No. 1 (2023): Jurnal Malikussaleh Mengabdi, April 2023
Publisher : LPPM Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/jmm.v2i1.10591

Abstract

Penyakit Tidak Menular (PTM) saat ini termasuk salah satu masalah kesehatan yang telah menjadi perhatian tingkat nasional maupun global, World Health Organization menunjukkan bahwa penyakit kardiovaskuler merupakan penyebab kematian tertinggi di negara- negara Asia Tenggara termasuk di Indonesia yaitu sebesar 37 %. Tingginya kadar kolesterol yang melebihi normal (Hiperkolesterol) dapat menjadi faktor risiko penyebab timbulnya berbagai macam penyakit tidak menular seperti peningkatan risiko penyakit hipertensi, obesitas, stroke dan jantung koroner. Kegiatan Pengabdian kepada Masyarakat ini bertujuan untuk mengetahui gambaran tingkat pengetahuan dan perilaku masyarakat di Desa Lampo Kabupaten Donggala terhadap komplikasi dan pencegahan Penyakit Kolesterol. Kegiatan Pengabdian kepada Masyarakat ini dilakukan dengan dilakukan dalam bentuk sosialisasi dan edukasi dengan menggunakan metode ceramah dan diskusi. Hasil kegiatan pengabdian masyarakat ini menunjukkan adanya peningkatan pengetahuan dan pemahaman serta perilaku yang baik terhadap komplikasi dan pencegahan Penyakit Kolesterol. Kegiatan ini juga dapat dijadikan sebagai upaya dalam mengatasi masalah kesehatan dengan menggunakan obat-obatan yang dapat dikonsumsi tanpa pengawasan dari dokter. 
Uji aktivitas afrodisiak ekstrak etanol daun cengkeh (Syzygium aromaticum L.) pada tikus putih jantan (Rattus norvegicus) Patala, Recky; Risnawati, Risnawati; Wulandari , Ayu; Yanuarty , Rezky; Handayani , Tien Wahyu
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 3 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i3.485

Abstract

Sex drive is what everyone needs to have a beautiful and harmonious sex life. Decreased sex drive is one of the factors that cause discord in relationships between men and women, and sexual dysfunction is a major concern. In Indonesia, this sexual disorder is most prevalent in men with a prevalence rate of 10% (all ages combined) and more than 50% occurs in the age group 50-70 years. The aim of this study was to determine the aphrodisiac effect of the extract by looking at several parameters, namely mount latency (ML), intromission frequency (IL), ejaculation latency (EL), mount frequency (MF), intromission frequency (IF), and ejaculation frequency (EF). This study used an experimental method with a post-test modified randomized control group design with 15 male white rats and 30 female white rats divided into 3 treatment groups with a ratio of (1: 2), each group consisting of 5 male rats and 10 female rats. Normal control group (NaCMC 0.5%), positive control group (X-Gra 52.5 mg/kgBB), and control test clove leaf extract sample at a dose of 250 mg/kgBB. Administration of extracts and comparators was only given to male white rats for 30 days. The results of this study indicate that clove leaf extract contains secondary metabolites of flavonoids, saponins, alkaloids, tannins, and strong antioxidants. The administration of clove leaf of extract at a dose of 250 mg/kg body weight showed a significant difference between the positive group and clove leaf of extract with a value of P < 0.05, this indicates that clove leaf of extract has aphrodisiac activity.
Post-Education Assessment of Patient Knowledge and Attitudes Toward Beyond Use Date (BUD) at Primary Health Centers in Palu City Susanto, Yuliet; Patala, Recky; Diana, Khusnul; Tandah, Muhammad Rinaldhi; Witanti, Alun; Bawiling, Viorenita Giovany; Nurfajar, Rifda; Jannah, Miftahul; Nurwalyani, Nurwalyani; Sultan, Asriana
Jurnal Mandala Pengabdian Masyarakat Vol. 6 No. 2 (2025): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpm.v6i2.645

Abstract

Promosi kesehatan di Puskesmas merupakan upaya pemberdayaan masyarakat untuk mencegah penyakit dan meningkatkan derajat kesehatan secara mandiri. Salah satu topik penting yang diangkat adalah pemahaman tentang Beyond Use Date (BUD), yaitu batas waktu penggunaan obat yang telah diracik atau setelah kemasan primernya dibuka. Masih banyak masyarakat yang belum memahami perbedaan antara BUD dan expired date, sehingga edukasi diperlukan. Kegiatan promosi dilakukan di ruang tunggu Apotek tiga Puskesmas di kota Palu yaitu: Puskesmas Bulili, Kamonji dan Mabelopura melalui penyuluhan menggunakan media leaflet, dengan peserta sebanyak 100 orang. Penyuluhan dipandu oleh mahasiswa Program Studi Profesi Apoteker Universitas Tadulako bersama Apoteker Puskesmas. Evaluasi dilakukan menggunakan kuesioner pasca-edukasi. Hasil menunjukkan bahwa tingkat pengetahuan pasien meningkat secara signifikan, dengan persentase jawaban benar mencapai 84,5%. Nilai rata-rata sikap yang diperoleh adalah 8,2, yang mengindikasikan kecenderungan positif. Hasil kegiatan menunjukkan peningkatan pengetahuan masyarakat mengenai BUD dan pentingnya memperhatikan batas penggunaan obat secara aman dan rasional. Kegiatan ini diharapkan dapat berkelanjutan sebagai sarana edukatif di layanan kesehatan primer
Effectiveness Test of Mangrove Leaf (Rhizophora Apiculata) on Decreasing Blood Glucose Levels and Pancreas Histopatology Streptozotocin Induced Male White Rats Joni Tandi; Mohammad Fahri; Nurul Fatma; Viani Anggi; Recky Patala; Tien Wahyu Handayani
Jurnal Penelitian Pendidikan IPA Vol 9 No 6 (2023): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i6.3789

Abstract

Hyperglycemia, a symptom of diabetes mellitus, can lead to oxidative stress, which is indicated by elevated malondialdehyde levels. Mangrove (Rhizophora apiculata) contains secondary metabolites of alkaloids, flavonoids, saponins and tanins, this can lessen how much oxidative stress there is in DM. This study intends to demonstrate the efficacy of mangrove extracts in lowering blood glucose levels and detecting pancreatic damage. The study used 30 male Wistar rats which were divided into 6 groups (group I: normal control, group II: negative and group III: positive control given glibenclamide 0.45 mg) and the test group (trial group). group IV: level 25 mg/kg BW, group V: level 50 mg/kg BW and VI: level 75 mg/kg BW) The DM model was made by streptozotocin induction. Pancreatic damage seen at 700 magnification saw pancreatic β cells as well as the islets of Langerhans' endocrine cells. The results of research on ethanol from mangrove leaves at levels of 75 mg/kg BW are substances that are effective at lowering blood sugar levels, which on average were 105 mg/dL with a hazard value of 1.2. When compared with glibenclamide mangrove extract is not equivalent to glibenclamide but has lowered glucose levels.
Anticancer Activity of Rosella Flowers (Hibiscus Sabdariffa l.) In HepG2 cells Viani Anggi; Recky Patala; Arfiah Arfiah; Niluh Puspita Dewi
Jurnal Penelitian Pendidikan IPA Vol 9 No SpecialIssue (2023): UNRAM journals and research based on science education, science applic
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9iSpecialIssue.6350

Abstract

The natural ingredients of rosella flowers have the potential as natural anti-cancer and chemopreventive agents, contain secondary metabolite compounds with cancer therapeutic mechanisms with inhibiting and killing cancer cells and their development through inhibition of apoptosis (cell death program) and in vitro inhibited cell flow. The study aims to identification of secondary metabolite compounds and also determine the cytotoxic activity of ethanol extract from the rosemary plant against HepG2 cancer cells. This study used by identification of secondary metabolite compounds of ethanol extract from the rosemary plant (Hibiscus sabdariffa L.) and the cytotoxicity test used with MTT assay on HepG2 liver cancer cells with a test concentration series of 12,5; 25; 50; 100; 200; 250; 500 and 1000 µg/ml. : The results showed the secondary metabolite compounds of rosella flowers have flavonoids, alkaloids, saponins and tannins and data of 50% cell growth inhibition activity, which was showed that rosella flower had IC50 values 629,919 μg/mL. The ethanol extract of rosella flowers have activity on HepG2 cells growth inhibition had considered moderately active anticancer activity
Profil senyawa metabolit sekunder dari fraksi n-heksana dan etil asetat daun cengkeh (Syzygium aromaticum L.) menggunakan LC-HRMS Rezky Yanuarty; Siti Nurhaliza; Halik Alamsyah; Joni Tandi; Muthmainah Tuldjanah; Ayu Wulandari; Kevin Maengko; Recky Patala
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1138

Abstract

The diversity of plants available in nature, the majority have the potential as a source of traditional medicine due to the presence of secondary metabolites in various parts of the plant, especially the leaves. The object of the study was clove leaves (Syzygium aromaticum L.), a plant species abundant in secondary metabolites including alkaloids, flavonoids, tannins, saponins, and steroids/triterpenoids. This research aims to compare the profile of secondary metabolites in clove leaves (Syzygium aromaticum L.) in the n-hexane and ethyl acetate fractions. The research methodology includes phytochemical screening of secondary metabolites of the n-hexane and ethyl acetate fractions of clove leaves (Syzygium aromaticum L.) with dye reagents and LC-HRMS analysis. Phytochemical screening of the n-hexane fraction confirmed the presence of steroids, while the ethyl acetate fraction confirmed flavonoids, tannins, and steroids. The results of identification using the LC-HRMS instrument on the N-Hexane and Ethyl Acetate fractions of clove leaves (Syzygium aromaticum L) using LC-HRMS contained phenolic, flavonoid and phenylpropanoid compounds. In the results of the chromatogram in the N-Hexane fraction, Rhamnetin compound was obtained which had an area percent of 0.362% with the highest area of 10954249. Meanwhile, in the results of the ethyl acetate fraction chromatogram, eugenol compounds were obtained with an area percent of 0.37% with the highest area of 33151358.
Co-Authors A, Faidil Afdal Akhmad Khumaidi Arfiah Arfiah Asriana Sultan Awilia, Nurkhaliza Ayu Wulandari Ayu Wulandari Ayu Wulandari Ayu Wulandari Bawiling, Viorenita Giovany Fahruddin Fahruddin Ficanata Adhiguna Toding Gunawan Pamudji Widodo Halik Alamsyah Handayani , Tien Wahyu Handayani, Kiki Rizki Handayani, Tien Wahyu I Made Sarwadana I Made Sarwadana Irnawati Irnawati Islamiati , Utami Isna Paula Joni Tandi Joni Tandi Joni Tandi, Joni Kevin Maengko Khusnul Diana Lidongi, Putri Marcelita M, Mariyani Magfiroh Magfiroh Maramis M Maria Kanan Mariyani Mariyani Mariyani , Mariyani Megawati Megawati Miftahul Jannah Mohammad Fahri Monica Sandra Makatang Monica Sandra Makatang Muhammad Rinaldhi Tandah, Muhammad Rinaldhi Muthmainah Tuldjanah Niluh Puspita Dewi Niluh Puspita Dewi Niluh Puspita Dewi, Niluh Puspita Nugroho , Agung Endro Nur Ikhwan Nur Sakina Nurfajar, Rifda Nurlina Ibrahim Nurul Fatma Nurul Ulzmi Nurwalyani, Nurwalyani Palumpun, Tri Olan Pasaribu, Meilinda Handayani Pratiwi, Dinda Praypelisa, Ipa Prinasari , Rezan Rezky Yanuarty Rianto Tanggo Doko Risnawati Risnawati Salsabila, Unik Hanifah Sarwadana, I Made Siti Nurhaliza Sri Hudayah Sri Mulyani Tandi, Jony Tien Wahyu Handayani Tien Wahyu Handayani Towulu, Dessy Gracelia Tri Olan Palumpun Utami, Indah Kurnia Viani Anggi Viani Anggi Viani Anggi Vidya Christin Witanti, Alun Wulandari , Ayu Yanuarty , Rezky Yanuarty, Rezky Yuliet Yuliet Yunlis Silintowe Kenta