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Solubility and Dissolution Study of Salicylamide Isadiartuti, Dewi; Widjaja, Bambang; Wijaya, Hendra; Ardhani Dwi Lestari, Maria Lucia
Berkala Ilmiah Kimia Farmasi Vol. 9 No. 2 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikfar.v9i2.42706

Abstract

Salicylamide belonged to the class of NSAIDs (non-steroidal anti-inflammatory drugs) which had analgesic and antipyretic effects similar to salicylic acetyl acid but were not converted to salicylic acid in the body. When used orally, salicylamide did not cause inflammation and bleeding in the stomach. Salicylamide was a weak acid compound (pKa 8,2) whose solubility was affected by the environmental pH. On oral administration, salicylamide passed through the digestive tract in the pH range of about 1,5 - 8,0. According to the Noyes-Whitney equation, drug dissolution was affected by its solubility. The aim of this study was to evaluate the relationship between the solubility and dissolution of salicylamide in several pH dissolution media. Solubility tests were carried out in dissolution media with pH 1,2, 4,5, and 6,5 with an ionic strength (µ) of 0,2 in a water bath at 37 ± 0,5 °C until a saturated solution was formed. The dissolution test was carried out in a dissolution media solution with the same pH as the solubility test, using a paddle type stirrer at 50 rpm at 37 ± 0,5 °C for 60 minutes. The level of dissolved salicylamide in the solubility test and dissolution test was determined using a spectrophotometer at λmax for each pH of the medium. Salicylamide solubility and dissolution efficiency values in 60 minutes (ED60) were analyzed by one-way ANOVA at α 0,05. The results showed that the solubility of salicylamide increased with increasing pH. Increasing the solubility of salicylamide increased its dissolution.Keywords: Salicylamide, Ph Effect, Solubility, Dissolution, Noyes-Whitney equation
The Effectiveness of Vitamin E Soft Capsules as an Antioxidant Putri, Syakirah Yasmin; Isadiartuti, Dewi; Isnaeni, Isnaeni; Aulya Farah Fahreza; Alvina Violita Mulyanto Putri; Zulfa Diana; Nafa Nazilatul Fatihah; I Gede Rekyadji Arimbawa; Alya Fakhirah; Talitha Nabilla Wijayanata; Muhammad Pramudya Pangestu; Azzalia Firdanthi; Oudrey Addriana; Umi Aida Rohma
Berkala Ilmiah Kimia Farmasi Vol. 11 No. 1 (2024): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikfar.v11i1.51902

Abstract

Antioxidants inhibited the oxidation of other molecules and played an important role in maintaining a healthy body. Antioxidants were found in fruits, vegetables, all parts of plants, and were present in the body as enzymes or products of metabolism. Vitamin E referred to a large number of natural or synthetic compounds, with alpha-tocopherol being the most active and widely distributed form in nature. Alpha-tocopherol was the most active antioxidant form of vitamin E and served as the primary lipophilic antioxidant in plasma, membranes, and tissues. The most important function of vitamin E was its antioxidant capability, counteracting free radical attacks that could damage cells and cause various degenerative diseases. Additionally, antioxidants helped reduce the effects of photoaging on the skin, potentiated anti-aging and anti-inflammatory activity, increased the rate of wound healing, and helped maintain healthy eyes and the immune system. One form of vitamin E dosage form was a soft capsule, which had several advantages, including the ease of filling the Active Pharmaceutical Ingredient (API) in liquid form, higher production capacity, and formulation uniformity compared to gelatin tablets or hard capsules. Soft capsule preparations also had rapid API release, which could result in achieving therapeutic blood levels more quickly and achieving greater bioavailability. This study aimed to evaluate soft capsule dosage forms in enhancing the effectiveness of vitamin E as an antioxidant. The research utilized review articles sourced from national and international journals, as well as scientific journals. The results showed that vitamin E supplementation in soft capsules could increase its effectiveness as an antioxidant.Keywords:  Soft Capsule, Increase Effectiveness, α-tocopherol, Vitamin E, Antioxidant
Pengaruh pH Basa terhadap Stabilitas Salisilamid Prasetyo, Wisnu; Isadiartuti, Dewi; Annuryanti, Febri; ambarwati, nadya
FARMASIS: Jurnal Sains Farmasi Vol 4 No 2 (2023): Vol. 4 No 2 (2023): Farmasis: Jurnal Sains Farmasi
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v4i2.7139

Abstract

Salisilamida adalah analgesik turunan salisilat dengan pembentukan ikatan amida antara gugus karboksil asam salisilat dan gugus amina. Salisilamida mempunyai masa kerja yang cepat, memiliki kalarutan yang tinggi dan toksisitas lebih rendah. Salisilamida bersifat asam lemah dengan pK 8,2. Hal ini dikarenakan salisilamida memiliki jumlah molekul terion lebih banyak, dengan banyaknya molekul yang terion membuat salisilamida mudah terhidrolisis dan menjadi tidak stabil, sehingga dilakukan uji stabilitas salisilamida untuk mengetahui pengaruh pH terhadap stabilitas salisilamida. Dengan adanya penelitian ini dapat membantu proses pengembangan obat dan formulasi sediaan salisilamida. Sebelum dilakukan pengujian, diperlukan validasi metode dari analisis yang digunakan yaitu KLT – Densitometri. Validasi yang dilakukan uji spesifisitas, uji linieritas, uji akurasi, dan uji presisi. Hasil validasi uji spesifisitas Rs sebesar 12, uji linieritas r  sebesar 0,9990, uji akurasi  persen perolehan kembali sebesar 98,7 kurang lebih 2,5 dan uji presisi dengan KV rata – rata sebesar 0,32 persen, sehingga dikatakan metode ini dapat digunakan untuk uji stabilitas salisilamida. Uji stabilitas dilakukan dengan melarutkan salisilamida dalam dapar pH basa (7,0; 8,0; 9,0; 10,0; dan 11,0) dengan konsentrasi 0,02 M dan kekuatan ion 0,2 dan diletakkan pada waterbath shaker suhu 40 derajat Celcius. Masing-masing sampel diteliti kadarnya pada 0, 1, 2, 4, dan 6 jam. Sampel diamati dengan menggunakan Kromatografi Lapis Tipis (KLT)-Densitometri. Pengamatan KLT – Densitometri dilakukan pada panjang gelombang 304 nm. Uji stabilitas yang diamati yaitu penetapan kadar salisilamida pada berbagai pH basa, penentuan orde reaksi, dan tetapan laju reaksi (k). Dari hasil penelitian didapatkan degradasi salisilamida dalam dapar pH basa mengikuti orde satu. Kemudian salisilamida dalam berbagai pH basa didapatkan nilai tetapan laju reaksi berturut – turut sebesar 2,30.10-2 kurang lebih 1,22.10-2; 3,73.10-2 kurang lebih 1,89.10-2; 2,06.10-2 kurang lebih 0,54.10-2; 3,64.10-2 kurang lebih 0,39.10-2; dan 1,40.10-2 kurang lebih 0,28.10-2 jam-1. Dari hasil analisis statistik ANOVA one way dan Tukey HSD dengan taraf signifikansi sebesar 0,05, diketahui bahwa pada masing – masing pH ditemukan adanya perbedaan bermakna nilai laju reaksi pada pH 8 dan pH 10 dan pada pH 11 nilai laju reaksi paling rendah dibandingkan lainnya. Rendahnya laju reaksi disebabkan efek resonansi dan resistensi serangan nukleofilik oleh ion hidroksida pada pH basa sehingga salisilamida menjadi stabil. 
Lecture Presentations Combined with Comic Story-Telling to Increase the Knowledge and Understanding of Elementary and Junior High School Students about Drugs Concerning Self-Medication Behavior Miatmoko, Andang; Mufariha, Mufariha; Retnowati, Dini; Paramanandana, Abhimata; Sugiyartono, Sugiyartono; Sari, Retno; Purwanti, Tutiek; Isadiartuti, Dewi; Hendradi, Esti
Journal of Community Research and Service Vol 6, No 2: July 2022
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jcrs.v6i2.35665

Abstract

Self-medication practice can result in medication errors due to limited public knowledge of pharmaceutical medicine, especially among school-aged adolescents, who are prohibited from doing self-medication. This study aimed to evaluate the students' knowledge and understanding of pharmaceutical medicine, pharmacists, and self-medication, and also the awareness to be wise and smart in responding to the use of pharmaceutical products for maintaining public health. The study was carried out by conducting the lecture on drugs and self-medication through a classical presentation and comic story to students of SDN Keputih 245 Elementary School and SMPN 19 Junior High School, Surabaya. Moreover, DAGUSIBU dance was also practiced. The students actively engaged in the class during the presentation. The results of the pre-and post-test evaluations showed that this lecture method had succeeded in increasing junior high school students' knowledge about medicine and DAGUSIBU. On the other hand, the pre-test scores of Elementary School students were better than the post-test, except for new knowledge related to the drug logo and classification. It suggests that the delivery methods were inappropriate for elementary school students. It can be concluded that school-age adolescents, especially in elementary and junior high schools, need assistance during self-medication. This community service activity by a presentation and comic telling methods successfully improved the knowledge of SMPN 19 Junior High School about drugs and DAGUSIBU; however, it needs a more straightforward explanation with attractive learning methods for delivering a lecture to Elementary School students.
Karakterisasi Kompleks Inklusi Asam Mefenamat - B-Siklodekstrin yang Dibuat dengan Metode Freeze Drying Setyawan, Dwi; Isadiartuti, Dewi
Jurnal Kefarmasian Indonesia VOLUME 1, NOMOR 1, 2009
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v1i1.2837

Abstract

Characterization of mefenamic acid- ,8-cyclodextrin inclusion complexes by freeze dryin method had been studied. Solid state mefenamic acid - B-cyclodextrin inclusion complex prepared by freeze drying method in 1:1 molar ratio. Mefenamlc acid, B-cyclodextrin, mefenamic acid - B-cyclodextrin physical mixture and inclusion complexes were characterized by Powder X-ray Diffraction (PXRD), Fourier Transform Infrared Spectroscop (FTIR) , Dijferential Thermal Analyzer (DT/1) and dissolution studies. The results showed the formation of inclusion complex between mefenamic acid and B-lcyclodextrin. In vitro dissolution rate studies of mefenamic acid, mefenamic acid - B-lcyclodextrin physical mixture and inclusion complex were conducted using basket method and water as dissolution medium. Mefenamic acid - B-lcyclodextrin inclusion complex showed increasing dissolution rate compared to me?znamic acid - B-cyclodextrin physical mixture and mefenamic acid.
PENDIDIKAN POLA HIDUP SEHAT PASCA PANDEMI COVID-19 SEBAGAI UPAYA MENJAGA KESEHATAN SISWA SMP DI MAGETAN Isadiartuti, Dewi; Sari, Retno; Diyah, Nuzul Wahyuning; Lestari, Maria Lucia Ardhani Dwi; Rudyanto, Marcellino; Kusumawati, Idha; Setyawan, Dwi; Rohana, Melissa; Dewanthy, Kyrana Sekar; Fauzia, Alfi Nur; Siammita, Dhea Anansya
Jurnal Dinamika Pengabdian Vol. 10 No. 1 (2024): JURNAL DINAMIKA PENGABDIAN VOL. 10 NO. 1 OKTOBER 2024
Publisher : Departemen Budidaya Pertanian Fakultas Pertanian UNHAS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jdp.v10i1.32996

Abstract

Pembelajaran tatap muka secara offline bagi pelajar sudah dimulai kembali setelah pandemi Covid-19 melanda Indonesia. Sejak pandemi ditetapkan WHO tanggal 11 Maret 2020, telah menyebabkan 5.956.561 orang terkonfirmasi positif dan sebanyak 153.599 orang meninggal dunia (per 21 Maret 2022) di Indonesia. Kembalinya proses belajar mengajar ke kondisi normal perlu diantisipasi dengan kesadaran dan tanggung jawab siswa terhadap protokol kesehatan yang dianjurkan pemerintah. Tujuan kegiatan ini adalah untuk meningkatkan pemahaman dan kesadaran siswa SMPN tentang pola hidup sehat dalam upaya menjaga kesehatan pasca pandemi Covid-19. Dalam program ini siswa didorong untuk menerapkan pola hidup sehat diantaranya dengan senantiasa menjaga kebersihan tangan dan menjaga daya tahan tubuh. Pengabdian masyarakat dilakukan dalam bentuk webinar dengan platform zoom diikuti oleh 59 siswa dari SMPN 1 Magetan dan diberikan dalam bentuk pre-test dan post-test, ceramah, diskusi dan pembuatan e-poster. Hasil kuesioner yang diberikan kepada peserta sebelum kegiatan diketahui 100% siswa telah mendapatkan vaksinasi dosis dua, 100 % siswa setuju proses pembelajaran pasca pandemi dilakukan secara luring, 100% siswa setuju mengikuti protokol kesehatan selama mengikuti kegiatan pembelajaran di sekolah, 73,58% siswa selalu menggunakan masker, 35,85% siswa mencuci tangan sebelum masuk sekolah, 41,51% siswa menjaga jarak dengan temannya, dan 1,89% siswa menderita penyakit infeksi Covid-19 selama proses pembelajaran luring pasca pandemi. Hasil evaluasi kegiatan berupa pre-test dan post test serta pembuatan e-poster diketahui terdapat peningkatan pemahaman siswa terhadap materi yang disampaikan dan semua peserta menyatakan setuju materi pola hidup sehat yang disampaikan dapat diaplikasikan dalam mengikuti proses pembelajaran di sekolah. ABSTRACT Offline face-to-face learning for students has started again after the Covid-19 pandemic hit Indonesia. Since the pandemic was declared by WHO on March 11 2020, it has resulted in 5,956,561 people being confirmed positive and 153,599 people dying (as of March 21 2022) in Indonesia. The return of the teaching and learning process to normal conditions needs to be anticipated with students' awareness and responsibility for the health protocols recommended by the government. The aim of this activity is to increase understanding and awareness of junior high school students about healthy lifestyles in an effort to maintain health after the Covid-19 pandemic. In this program, students are encouraged to adopt a healthy lifestyle, including always keeping their hands clean and maintaining their immune system. Community service was carried out in the form of a webinar with a zoom platform attended by 59 students from SMPN 1 Magetan and given in the form of pre-test and post-tests, lectures, discussions and making e-posters. The results of the questionnaire given to participants before the activity showed that 100% of students had received the second dose of vaccination, 100% of students agreed that the post-pandemic learning process would be carried out offline, 100% of students agreed to follow health protocols while participating in learning activities at school, 73.58% of students always wearing masks, 35.85% of students washing their hands before entering school, 41.51% of students keeping their distance from their friends, and 1.89% of students suffering from Covid-19 infection during the post-pandemic offline learning process. The results of the evaluation of activities in the form of pre-test and post-tests and making e-posters showed that there was an increase in students' understanding of the material presented and all participants agreed that the healthy lifestyle material presented could be applied in following the learning process at school. Keywords: Healthy lifestyle, Covid-19, post-pandemic, student education, maintaining health.
Pengaruh Jumlah Polimer terhadap Karakteristik Fisik dan Pelepasan Nanopartikel Fraksi Diterpen Lakton Sambiloto - Kitosan Sari, Retno; Paramanandana, Abhimata; Isadiartuti, Dewi; Rahayyu, Annisa Maulidia
JSFK (Jurnal Sains Farmasi & Klinis) Vol 7 No 2 (2020): J Sains Farm Klin 7(2), Agustus 2020
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.7.2.99-106.2020

Abstract

The diterpene lactone fraction of Andrographis paniculata Nees (sambiloto) (FDTLS) main compound is andrographolide. Andrographolide has poor bioavailability, high lipophilicity, and low solubility. Entrapping poorly soluble substances into a hydrophilic polymer, such as chitosan, could improve their dissolution, bioavailability, and activity. The purposes of this study were to improve the FDTLS dissolution and to compare the effect of different amounts of chitosan on physical characteristics, entrapment efficiency, and FDTLS release from nanoparticles, which was made by the ionic gelation-spray drying method using tripolyphosphate as a crosslinker. The nanoparticles were prepared with different FDTLS-chitosan ratios = 1:2 (FK1), 1:2.5 (FK2) and 1:3 (FK3). The nanoparticles were evaluated for its morphology, physical state using differential thermal analysis (DTA), Fourier-transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), entrapment efficiency, and drug release. All the nanoparticles' formulas had a spherical shape and FK2 showed the smoothest surface with the highest enthalpy. FDTLS-chitosan nanoparticles diffractogram showed a more amorphous form. The FDTLS-chitosan nanoparticles entrapment efficiency was 29.01-32.69%. The FDTLS-chitosan nanoparticles showed an increased dissolution rate by 1.6 times compared to the FDTLS substance. The study concludes that the formation of nanoparticles using chitosan by ionic gelation-spray dry method could improve the dissolution of FDTLS.
Pemanfaatan Teh dan Rempah-rempah Khas Indonesia dalam Pemeliharaan Kesehatan Warga di Sumba Timur Menghadapi Pandemi Covid-19: Tea and Indonesian Spices for Improving Health for People in East Sumba for Facing Pandemic COVID-19 Sulistyowaty, Melanny Ika; Purwanto, Djoko Agus; Agil, Mangestuti; Ekowati, Juni; Isadiartuti, Dewi; Hendradi, Esti; Purwitasari, Neny; Yusniasari, Putri Antika
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 4 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i4.7043

Abstract

The coronavirus (SARS-CoV-2) has infected nearly 4 million people worldwide. This virus was first identified in Wuhan, China, in December 2019. Every day positive cases of Covid-19 are increasing in the world. Experts are still trying to find a vaccine to prevent this virus, one of which is by increasing the body's resistance (immunity). The use of family medicinal plants (TOGA) or tea, a drink that we usually drink every day is believed to increase one's body immunity. The content of natural chemicals in tea such as EGCG and curcumin found in the rhizomes have antioxidant activity and is clinically proven to increase a person's immunity.
PELATIHAN DISPENSING ASEPTIK SEDIAAN STERIL DI LAYANAN KESEHATAN KOTA MAKASSAR CITY DAN SEKITARNYA: Training on Aseptic Dispensing of Sterile Preparations in The Health Services of Makassar and Surroundings Isadiartuti, Dewi; Sari, Retno; Rijal, Muh. Agus Syamsur; Ratri, Dinda Monika Nusantara; Retnowati, Dini; Rudyanto, Marcellino; Miatmoko, Andang
JAMAS : Jurnal Abdi Masyarakat Vol. 3 No. 1 (2025)
Publisher : Forind Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62085/jms.v3i1.172

Abstract

Sediaan steril adalah sediaan yang tidak boleh mengandung mikroorganisme, partikel, serta sedapat mungkin dibuat isotonis. Kondisi steril tersebut harus dapat dijamin oleh apoteker sampai sediaan digunakan oleh pasien. Salah satu jenis pelayanan kefarmasian yang dilakukan oleh apoteker di fasilitas kesehatan adalah disepensing sediaan steril. Proses dispensing sediaan steril memerlukan teknik aseptis. Teknik aseptis merupakan salah satu aspek penting yang perlu diperhatikan oleh apoteker dalam menjalankan praktik kefarmasian khususnya di rumah sakit. Makassar yang merupakan ibukota Provinsi Sulawesi Selatan merupakan kota keempat terbesar di Indonesia. Kota Makassar merupakan tempat tinggal bagi lebih dari 15% penduduk Provinsi Sulawesi Selatan. Jumlah penduduk yang terus meningkat dan kualitas sumber daya yang baik sangat berguna untuk mendorong pertumbuhan ekonomi. Namun, jika tidak didukung dengan sumber daya manusia yang berkualitas, masalah sosial di Kota Makassar akan semakin meningkat. Salah satu cara dalam meningkatkan sumber daya manusia dapat melalui pengabdian masyarakat. Tujuan dari pengabdian masyarakat adalah untuk meningkatkan pengetahuan serta ketrampilan apoteker dalam hal dispensing aseptik sediaan steril di layanan kesehatan Kota Makassar dan sekitarnya. Kegiatan dilaksanakan di Auditorium Universitas Islam Makassar pada hari Sabtu 19 Oktober 2024 diikuti 34 peserta apoteker dari Rumah Sakit dan Puskesmas yang melakukan layanan pengelolaan sediaan steril. Dari hasil pre/post test tentang materi yang diberikan dan evaluasi kegiatan menunjukkan peningkatan pemahaman peserta dan respon positif terhadap pelatihan yang diselenggarakan oleh tim pengabdian masyarakat Fakultas Farmasi Universitas Airlangga. Harapan peserta pelatihan di masa mendatang kegiatan diperbanyak dan alokasi waktu pelaksanaan dapat lebih diperpanjang.
Nanostructured Lipid Carrier (NLC) as a Topical Drug Delivery System : A Review Latifah, Luluk; Hendradi, Esti; Isadiartuti, Dewi
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 2 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.006789

Abstract

Nanostructured Lipid Carrier (NLC) appears as the next generation of lipid nanoparticles which overcomes the weaknesses of Solid Lipid Nanoparticles (SLN). NLC is a delivery system that offers several advantages, such as significantly improved entrapment efficiency, reduced drug expulsion during long-term storage, and increased contact between the drug and the stratum corneum, thereby enhancing drug penetration. The methods used to manufacture NLC have high energy-required such as high-pressure homogenization and high shear homogenization, low energy-required such as microemulsification and phase inversion, and very low or no energy-required such as solvent evaporation and solvent injection. The basic components of an NLC are solid lipids, liquid lipids, and surfactants or mixtures of surfactants. This narrative review refers to several previously published databases on the types, preparation methods, and physical properties of NLC. This review focuses on descriptions related to the NLC as a topical drug delivery system.
Co-Authors Abhimata Paramanandana Alvina Violita Mulyanto Putri Alya Fakhirah Annisa Maulidia Rahayyu Ardhani Dwi Lestari, Maria Lucia Asri Darmawati Aulya Farah Fahreza Azzalia Firdanthi Bambang Widjaja Betari, Sita Desti Dewanthy, Kyrana Sekar Dinda Monika Nusantara Ratri Dinda Monika Nusantara Ratri Dini Retnowati Dini Retnowati Diyah, Nuzul Wahyuning Djoko Agus Purwanto Dwi Setyawan Esti Hendradi Fauzia, Alfi Nur Febri Annuryanti Firdausiah Fania Dwi Putri Putri Frida Magdalena Heinrich Dengi Hendra Wijaya Herra Studiawan I Gede Rekyadji Arimbawa I Gusti Ayu Adhi Aryapatni Idha Kusumawati Imamatin Nufus Melania Isnaeni Isnaeni Juni Ekowati Latifah, Luluk Mangestuti Agil Marcellino Rudyanto Maria Lucia Ardhani Dwi Lestari Melanny Ika Sulistyowati Melanny Ika Sulistyowaty Miatmoko, Andang Mufariha, Mufariha Muh Agus S Rijal Muhammad Agus Syamsur Rijal Muhammad Agus Syamsur Rijal Muhammad Ilham Royyan Nafi Muhammad Pramudya Pangestu Nadya Ambarwati Nafa Nazilatul Fatihah Noor Erma Nasution Sugijanto Noorma Rosita Nuzul Wahyuning Diyah Oudrey Addriana Paramita, Diajeng Putri Prof. Dr. Retno Sari, M.Sc., Apt. Purwitasari, Neny Putri Hamidah Khairunnisa Putri, Syakirah Yasmin Rahayyu, Annisa Maulidia Retno Sari Rijal, M. Agus Syamsur Rohana, Melissa SETIAWAN, Catur Dian Siammita, Dhea Anansya Sugijanto Kartosentono Sugiyartono Sugiyartono Sugiyartono, Sugiyartono Suko Hardjono Suwaldi . Talitha Nabilla Wijayanata Tristiana Erawati Tutiek Purwanti Tutik Sri Wahyuni Umi Aida Rohma Virnanda Syafira Hartatiningrum Widji Soeratri Wisnu Prasetyo Yusniasari, Putri Antika Zulfa Diana