Claim Missing Document
Check
Articles

The Evolving Brain: Unraveling the Forces Shaping Human Cognition R. Tjandrawinata, Raymond
Asian Journal of Social and Humanities Vol. 3 No. 4 (2025): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v3i4.475

Abstract

This interdisciplinary study explores the evolution of the human brain by integrating perspectives from anthropology, neuroscience, evolutionary biology, and technology studies. It delves into the factors driving brain expansion over time, including social complexity, dietary transitions, tool use, and the development of language. By synthesizing primary and secondary data, the research highlights the interplay between cognitive development and environmental pressures, showcasing how human neural architecture was shaped by adaptive responses to changing conditions. The findings reveal that evolutionary adaptations not only influenced brain size and structure but also laid the groundwork for cognitive resilience, particularly in the face of aging and modern technological advancements. This study underscores the profound impact of social and environmental challenges on brain evolution and its ongoing plasticity. Furthermore, it addresses critical questions about how rapid technological shifts are shaping cognitive functions and neural pathways today. By examining the past, present, and future trajectories of the human brain, this research provides a comprehensive framework for understanding its evolutionary processes and offers insights into navigating the challenges of an increasingly complex and technology-driven world.
Ethics and Intellectual Property Rights in Genetic Therapy R. Tjandrawinata, Raymond; Heliany, Ina; Soelistyo Budi, Henry
Asian Journal of Social and Humanities Vol. 3 No. 5 (2025): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v3i5.500

Abstract

Genetic technology, particularly CRISPR-Cas9, has transformed the paradigm of treating genetic diseases by offering new hope for more effective and precise therapies. However, this advancement also presents significant ethical and intellectual property rights (IPR) challenges. This article explores the impact of patents on the development and accessibility of genetic therapy, as well as the ethical issues arising from human genetic modification, especially at the germline level. Using a qualitative analytical approach that combines literature reviews and case studies, the article examines patent disputes that have emerged in the development of CRISPR and how applied patent policies can exacerbate inequities in access to critically needed medical therapies. Furthermore, the article discusses ethical concerns regarding the misuse of genetic technology and its potential impact on future generations. In conclusion, the article proposes the need for more inclusive and balanced policies that prioritize both innovation and accessibility, as well as strict regulations to ensure the safe and ethical application of genetic technology, while considering broader social and cultural impacts.
The Intersection of Max Planck’s Metaphysical Assertion and Christian Theology: A Pragmatic Review of Consciousness and Creation R. Tjandrawinata, Raymond; B. Atawolo, Andreas
Devotion : Journal of Research and Community Service Vol. 5 No. 12 (2024): Devotion: Journal of Community Research
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/devotion.v5i12.25389

Abstract

This systematic review explores the intersection of Max Planck's assertion that "matter is a derivative of consciousness" with key concepts in Christian theology, particularly creation, existence, and the imago Dei. The study aims to investigate how Planck's views align with and enrich theological doctrines, fostering dialogue between science and faith. The objective is to analyze interdisciplinary literature to uncover complementary understandings of the cosmos' origin and nature, drawing from scientific insights and Christian theological frameworks. A qualitative methodology is employed, comprising a systematic analysis of scholarly articles, theological texts, and scientific literature that address consciousness, metaphysics, and divine creation. The findings reveal significant alignment between Planck's concept of consciousness as foundational to matter and Christian beliefs about God’s creative agency and humans as bearers of the imago Dei. This synthesis enhances comprehension of the cosmos as a creation sustained by an underlying consciousness, aligning with the theological principle of divine intentionality. In conclusion, this review highlights the potential for meaningful dialogue between scientific and theological perspectives, offering a unified understanding of existence that bridges the material and metaphysical realms.
COMPARATIVE COMPETITION LAW IN HEALTHCARE: A REVIEW OF U.S. AND INDONESIAN REGULATORY APPROACHES Tjandrawinata, Raymond R.
International Journal of Social Service and Research Vol. 5 No. 3 (2025): International Journal of Social Service and Research
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/ijssr.v5i3.1210

Abstract

The rapid expansion of digital health services and telemedicine introduces new dimensions to competition law enforcement in healthcare. This paper explores strategic recommendations to enhance Indonesia's competition law in healthcare by focusing on strengthening regulatory institutions, improving judicial consistency, fostering private enforcement mechanisms, and developing targeted policies for emerging digital health markets. This study employs a comparative legal analysis approach, integrating qualitative and normative research methods, to examine the effectiveness of existing competition law frameworks governing healthcare in the United States and Indonesia, identifying best practices, challenges, and opportunities for improvement. The findings reveal stark contrasts in competition law enforced between the two countries, particularly in market concentration, regulatory oversight, judicial intervention, and private litigation mechanisms. By adopting a framework that fosters industry sustainability while preventing anti-competitive behavior, Indonesia can create a more competitive, innovative, and accessible healthcare system that benefits both pharmaceutical companies and consumers alike.
Mikrobiota–Usus–Otak sebagai Jaringan Metabolik dan Pengatur Kontrol Energi Raymond R. Tjandrawinata
MEDICINUS Vol. 38 No. 12 (2025): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/fy2cd832

Abstract

This article examines the gut–brain axis in the pathophysiology of type 2 diabetes as a complex communication network that shapes glucose metabolism, systemic inflammation, gut hormone function, and eating behavior. By integratingevidence from metagenomic, neuroendocrine signaling, and modern pharmacotherapy studies, the article argues that type 2 diabetes is not merely a glycemic disorder, but also an internal ecological disruption involving microbiota interactions, theenteric nervous system, the vagus nerve, and metabolic regulatory centers in the brain. This perspective also highlights the clinical implications of emerging therapeutic agents such as GLP-1 agonists and dual GIP/GLP-1 agonists. This articleconceptualizes type 2 diabetes as an interorgan communication disorder that can be ameliorated through multilevel interventions including microbiota modulation, restoration of incretin, and precision nutrition strategies.
Reassessing Diversion and Restorative Justice in Indonesia’s Juvenile Criminal System: Legal Paradigms, Policy Gaps, and Implementation Challenges Heliany, Ina; Tjandrawinata, Raymond R
JURNAL AKTA Vol 12, No 4 (2025): December 2025
Publisher : Program Magister (S2) Kenotariatan, Fakultas Hukum, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/akta.v12i4.46142

Abstract

Indonesia’s juvenile criminal justice system has embraced diversion and restorative justice as foundational principles following the enactment of Law No. 11 of 2012 on the Juvenile Criminal Justice System. This study critically examines the legal frameworks underpinning these principles, explores the policy gaps, and evaluates the implementation challenges that have emerged in practice. Employing a socio-legal qualitative methodology, this paper reviews statutory provisions, policy documents, and empirical research findings on diversion and restorative justice in Indonesia. The results reveal that while Indonesia’s legal reforms align with international standards on juvenile justice, significant inconsistencies persist in the practical application of diversion policies. Key barriers include uneven regional implementation, lack of standardized procedures, insufficient training for law enforcement, and societal resistance rooted in a punitive legal culture. The discussion offers a comprehensive analysis of these challenges and suggests strategic pathways to strengthen the restorative justice framework. The paper concludes by recommending policy reforms that incorporate local wisdom, enhance institutional capacity, and promote community involvement to ensure sustainable and effective juvenile justice practices in Indonesia.
Rekonseptualisasi Faktor Risiko dalam Kedokteran 2025 Raymond R. Tjandrawinata
MEDICINUS Vol. 39 No. 1 (2026): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/2ejq6e75

Abstract

The term “new risk factors” in the medical literature of 2025 rarely refers to the discovery of previously unknown disease determinants; rather, it reflects an epistemic shift in how risk is defined, measured, and interpreted. This perspectivehighlights how advances in objective measurement technologies, large-scale cohort analyses, and genetics-based causal approaches have brought renewed attention to factors that were previously under recognized or oversimplified. By examining examples such as multidimensionally measured sleep irregularity, wildfire smoke exposure as a cardiovascular determinant, chlorpyrifos pesticide exposure in neurodegenerative disease, and debates surrounding immune-relateddisease causality which assessed through Mendelian randomization, this article demonstrates that the “novelty” of riskfactors more often lies in the breadth of disease spectra and the depth of biological inference rather than in the variables themselves. Obesity and cancer are used as a conceptual framework to illustrate how clinical redefinition can reshape riskstratification and preventive strategies. This perspective argues that progress in modern medicine should not be measured by the expansion of risk factor lists, but by the capacity of scientific systems to assess risk with greater precision, contextual awareness, and orientation toward clinically meaningful outcomes.
Justice and Regulation in Pharmaceutical Patents: A Comparative Philosophical Inquiry into India and Indonesia (1970–2024) Tjandrawinata, Raymond R.
Jurnal Impresi Indonesia Vol. 4 No. 11 (2025): Jurnal Impresi Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v4i11.7225

Abstract

This article traces the evolution of pharmaceutical patent regimes in India and Indonesia through a jurisprudential and philosophical lens, positioning justice, certainty, and protection as the three normative pillars of evaluation. The theoretical framework draws on John Rawls’s theory of distributive justice, Satjipto Rahardjo’s concept of progressive law, and Barry Mitnick’s theory of the political economy of regulation. Historical analysis reveals two epistemologically distinct trajectories. Since 1970, India has developed a legal system that balances exclusive rights and public welfare through substantive mechanisms such as Section 3(d), compulsory licensing, and drug price control under the National Pharmaceutical Pricing Authority (NPPA). Indonesia, by contrast, initially adopted a TRIPS-compliant positivist approach and began transitioning only in 2024 toward a more reflective and justice-oriented patent regime through the enactment of Law No. 65/2024 on Patents. The study argues that the fairness of a patent system should not be measured by its capacity to create monopolies of knowledge but by its effectiveness in distributing the benefits of technology to those most in need. It concludes with the formulation of a Balanced Patent Justice Framework (BPJF) a normative model integrating Rawlsian fairness, Satjiptian humanism, and Mitnickian institutional design to construct a pharmaceutical patent regime that is not only efficient but also morally sustainable.
Analysis of State Responsibility for Health Rights in Indonesia: Integrating Legal Positivism and Justice Theory Tjandrawinata, Raymond R.; Heliany, Ina
Eduvest - Journal of Universal Studies Vol. 5 No. 12 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i12.52613

Abstract

This research examines the legal and moral dimensions of the state's responsibility for the right to health in Indonesia by synthesizing legal positivism and contemporary theories of justice. Focusing on Law No. 17 of 2023 on Health and the National Health Insurance scheme (Jaminan Kesehatan Nasional, JKN), the research argues that formal legal validity alone is insufficient to discharge the state’s constitutional obligations. While Indonesia has constructed a procedurally coherent health law framework that satisfies positivist criteria of legality, significant gaps remain in the realization of substantive justice, particularly for disadvantaged populations. By juxtaposing H.L.A. Hart’s conception of legal validity with John Rawls’s theory of justice as fairness, this study demonstrates that the legitimacy of health law must be assessed not only by its formal pedigree but also by its distributive consequences. The research concludes that state responsibility for health rights requires an integrated approach in which legal positivism is complemented—and normatively corrected—by justice-based evaluation, thereby proposing a dual-threshold conception of state responsibility in health law that distinguishes legal validity from normative legitimacy through doctrinal analysis and normative institutional evaluation. This study conceptually reframes state responsibility for social rights as a dual-threshold structure in which formal legality constitutes a necessary condition of obligation, while distributive justice operates as an independent condition of legitimacy.
Ansietas pada Lansia: Prevalensi, Faktor Penanda, dan Penanganannya Raymond R. Tjandrawinata
MEDICINUS Vol. 39 No. 2: MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/qefshn93

Abstract

Anxiety in older adults is a prevalent mental health issue, yet it is frequently underrecognized due to the overlap symptoms with physical illnesses and age-related psychosocial changes. This article reviews the global prevalence, key risk markers,and evidence-based management approaches. Numerous studies indicate that anxiety in older adults is associated with chronic medical conditions (including pain), functional gastrointestinal disorders such as irritable bowel syndrome (IBS),low level of physical activity, and unhealthy dietary patterns. Evidence regarding direct association between serum vitamin D levels and anxiety in older adults remains inconsistent; however, emerging evidence suggests an indirect associationmediated through the role of vitamin D in gastrointestinal health and inflammatory process. Management of anxiety in older adults is recommended to follow a biopsychosocial approach, prioritizing psychological interventions such as cognitive behavioral therapy (CBT) and lifestyle modification, and selective pharmacotherapy reserved for moderate to severe cases.
Co-Authors Achmad K. Harzif Agung Endro Nugroho Agung Endro Nugroho Andon Hestiantoro Andri Prasetiyo Anindini Winda Amalia Anindyajati Anindyajati Anita Artarini Armini Syamsidi ARTARINI, ANITA B. Atawolo, Andreas Babu, Murali Mohan Budi Wiweko Caroline G. Puspita CATUR RIANI Danang Agung Yunaidi Dayana, Hepy Debbie S. Retnoningrum Debbie S. Retroningrum DEBBIE SOEFIE RETNONINGRUM Dewi Riskha Nurmalasari Diana Nur Afifah Esti Mumpuni Esti Mumpuni Esti Mumpuni, Esti Gayatri, Anggi Gita Pratama Hapsari, Riani Harry Martha Wijaya Hartati Tuna, Hartati Heliany, Ina Henry Soelistyo Budi Henry Soelistyo Budi, Henry Soelistyo Herbert Situmorang Herbert Situmorang Huda Shalahudin Darusman Indriawati, Iin Irsan Hasan Ismaya, Wangsa T. Kaka Renaldi Kanadi Sumapradja Krisnayanti, Ni Putu Eka Kristiana, Hery Kristiana, Hery Laurentia Stephani Liana W. Susanto Lilik Sulastri Luh Putu Nurshanti, Ni Maggy T. Suhartono Maggy T. Suhartono Maggy Thenawidjaja Suhartono Marcellus Simadibrata Martha Wijaya, Harry Melva Louisa Murali Mohan Babu Murdani Abdullah Nafrialdi Nafrialdi Nailufar, Florensia Nailufar, Florensia Ni Luh Putu Nurshanti Novia Tri Astuti Novia Tri Astuti Novitasari, Putri Rachma Permanasari, Silmi Citra Rachman, Andika Raden Muharam Natadisastra Retroningrum, Debbie S. Santi Tan Saut Horas Hatoguan Nababan Setiabudy, Rahajuningsih D Shirly Kumala SILMI MARIYA Simatupang, Stefeny Theresia Sinaga, Wenny S.L. Soelistyo Budi, Henry Susanto, Liana W Suwijiyo Pramono Suwijiyo Pramono Tan, Santi Viedya Novalinda Said Wangsa T. Ismaya Wangsa Tirta Ismaya Widjaja, Nadia Winoto, Imelda L Winoto, Imelda L Yanti Lim Zaelani, Bella Fatima Dora