Article Per Year (5 Year)
p-Index From 2021 - 2026
6.876
P-Index
This Author published in this journals
All Journal HAYATI Journal of Biosciences Journal of Food and Pharmaceutical Science Indonesian Journal of Biotechnology The Indonesian Biomedical Journal Science and Technology Indonesia Jurnal Akta Jurnal Fitofarmaka Indonesia Jurnal Pro Hukum : Jurnal Penelitian Bidang Hukum Universitas Gresik JFIOnline Jurnal Ilmu Kefarmasian Indonesia Jurnal Jamu Indonesia JURNAL RECTUM: Tinjauan Yuridis Penanganan Tindak Pidana Devotion: Journal of Research and Community Service Narra J International Journal of Social Service and Research Jurnal Impresi Indonesia International Journal of Science and Society (IJSOC) Journal Of World Science MEDICINUS Journal of Law, Poliitic and Humanities The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy INJURITY: Journal of Interdisciplinary Studies Eduvest - Journal of Universal Studies Journal of Social Science Al Makki Health Informatics Journal Journal of Food and Pharmaceutical Sciences Asian Journal of Social and Humanities Indonesian Journal of Jamu
Raymond R. Tjandrawinata
Fakultas Bioteknologi, Universitas Katolik Indonesia Atma Jaya
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

Published : 66 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 66 Documents
Search

 3   4   5   6   7 
Disfagia dalam Perspektif Klinis Kontemporer Raymond R. Tjandrawinata
MEDICINUS Vol. 39 No. 3 (2026): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/r1kbev80

Abstract

Dysphagia is a clinical symptom with diverse etiologies that is often narrowly interpreted as a neurological disorder or mechanical obstruction, however, recent literature indicates that it may present as a dominant symptom in chronictonsillopharyngitis with acute exacerbation. This narrative perspective review discusses the variability of dysphagia manifestations, underlying pathophysiological mechanisms, and the implications for management in inflammatorytonsillopharyngitis compared to dysphagia due to stroke, neurological, and neoplastic conditions, emphasizing that inflammatory dysphagia related to tonsillopharyngitis is potentially reversible and gives favourable response to cultureguidedantibiotics, short-term corticosteroids, as well as dietary modification. Early recognition of these clinical variations is essential to improve diagnostic accuracy and patients’ quality of life.dysphagia, chronic tonsillopharyngitis, acute exacerbation, oropharynx inflammation, clinical management
Harmonization of International Patient Law in Biotechnology: Strategies For Enhancing Innovation And Global Access Raymond R. Tjandrawinata; Henry Soelistyo Budi
Journal of Law, Politic and Humanities Vol. 5 No. 2 (2025): (JLPH) Journal of Law, Politic and Humanities
Publisher : Dinasti Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/jlph.v5i2.1146

Abstract

The fragmented global patent landscape poses significant challenges for biotechnology, one of the most innovative sectors of the 21st century. Despite the potential to revolutionize healthcare and agriculture, differences in patent regulation between jurisdictions impede progress, limit equitable access to therapies, and complicate international collaboration. This paper examines the key regulatory frameworks in the United States, the European Union, Japan, and China, focusing on the inherent strengths and challenges of each, by analyzing case studies, such as CRISPR gene editing and CAR-T therapy. The article identifies strategies to deal with ethical dilemmas, intellectual property rights differences, and cross-border enforcement issues. The analysis in this publication encourages harmonization initiatives through regional agreements, international dialogue, and open innovation models to promote global access and sustainable innovation.
Deprivasi Tidur dan Disregulasi Nafsu Makan Raymond R. Tjandrawinata
MEDICINUS Vol. 39 No. 4 (2026): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/mq82ds44

Abstract

Sleep deprivation is a biological factor that is often overlooked in appetite regulation. However, growing evidence indicates that disturbances in sleep duration and quality, as well as circadian misalignment can shift hunger–satiety control through hormonal, metabolic, and brain reward system mechanisms. This perspective review discusses the latest evidence regarding the roles of leptin, ghrelin, insulin, stress hormones, circadian rhythms, and chrononutrition in the association between sleep and appetite, highlighting its clinical relevance for general medical practice in the prevention and management of metabolic disorders.
Harnessing Artificial Intelligence in Generic Formulation Development and Life Cycle Management - A Comprehensive Review Murali Mohan Babu; Ni Luh Putu Nurshanti; Harry Martha Wijaya; Raymond R. Tjandrawinata
Al Makki Health Informatics Journal Vol. 3 No. 1 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i1.45

Abstract

Artificial intelligence (AI) is revolutionizing the pharmaceutical industry by enhancing efficiency, precision, and cost-effectiveness in drug development. This study explores the application of AI in the lifecycle management of generic drugs, focusing on key stages such as active pharmaceutical ingredient (API) synthesis, excipient selection, pre-formulation studies, bioequivalence testing, and regulatory compliance. By leveraging machine learning algorithms, AI facilitates predictive modeling, risk assessment, and optimization of drug formulation processes, reducing time-to-market and improving scalability. Despite significant advancements, challenges such as data quality, algorithm transparency, and infrastructure limitations persist, particularly in resource-constrained settings. This review highlights case studies and emerging technologies that address these challenges, providing actionable insights for pharmaceutical stakeholders. The study also discusses AI's potential to streamline supply chain logistics, enhance accessibility, and ensure regulatory adherence. By integrating AI across all stages of generic drug development, this research underscores its transformative potential in improving drug affordability, accessibility, and patient outcomes globally.
Resistensi Insulin sebagai Poros Disfungsi Ovulasi pada Polycystic Ovary Syndrome Raymond R. Tjandrawinata
MEDICINUS Vol. 39 No. 5 (2026): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/wnqbb620

Abstract

Insulin resistance in polycystic ovary syndrome (PCOS) is intrinsic in nature and not merely a consequence of obesity. Postreceptorphosphorylation abnormalities, particularly excessive serine phosphorylation of the insulin receptor and insulin receptor substrate, impair the activation of PI3K/Akt pathway, resulting in compensatory hyperinsulinemia. This conditionstimulates CYP17A1 expression in ovarian theca cells, suppresses hepatic synthesis of sex hormone-binding globulin, and creates a hormonal milieu that disrupts follicular maturation, ultimately leading to oligo-anovulation. The improvementin ovulation reported with the use of glucagon-like peptide-1 (GLP-1) receptor agonists is better understood as an indirect consequence of systemic metabolic improvement. The bioactive fraction DLBS3233 acts at a more downstream level,restoring tyrosine phosphorylation and glucose transporter-4 (GLUT-4) expression by modulating peroxisome proliferatoractivated receptor (PPAR)-γ. Positioning insulin resistance as the central pathophysiological axis enables a more precisetherapeutic approach aligned with the physiological mechanisms underlying ovulatory dysfunction in PCOS.
Nutritional composition and action mechanism of Channa striata meat in wound healing: A systematic review Hapsari, Riani; Tjandrawinata, Raymond
Narra J Vol. 5 No. 3 (2025): December 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i3.2903

Abstract

Wound healing is a complex biological process requiring adequate nutritional support, particularly proteins, amino acids, fatty acids, and essential minerals. Snakehead fish (Channa striata) has been traditionally consumed in Southeast Asia to accelerate recovery after surgery and childbirth. Emerging evidence suggests that its nutritional composition plays a pivotal role in tissue repair. The aim of this systematic review was to consolidate evidence on the nutritional composition of C. striata and elucidate its mechanisms of action in wound healing based on preclinical and clinical studies. A systematic search was conducted across PubMed, ScienceDirect, ProQuest, and Google Scholar for studies published between 2000 and 2023, following PRISMA 2020 guidelines. Eligible studies included biochemical analyses, in vitro and in vivo preclinical studies, and clinical trials assessing the wound-healing effects of C. striata. Data extraction covered nutrient composition, study design, wound-healing parameters, and mechanistic pathways. Out of 2898 identified studies, 22 of them met the inclusion criteria: ten biochemical composition studies, nine preclinical investigations, and four clinical trials. C. striata extract demonstrated high levels of albumin (0.76–10.73 g/100 g), essential and non-essential amino acids (notably glutamic acid, arginine, and glycine), fatty acids (palmitic, arachidonic, linoleic), and minerals such as zinc and copper. Preclinical models consistently showed enhanced fibroblast proliferation, epithelialization, tensile strength, and collagen deposition. Clinical studies in post-cesarean patients reported significant improvements in wound healing scores, uterine involution, pain reduction, and biomarker modulation (VEGF, IL-6, MMP-9). In conclusion, C. striata exhibits promising wound-healing potential attributable to its rich nutrient profile and multi-pathway mechanisms involving collagen synthesis, angiogenesis, and immunomodulation. However, the limited number of clinical trials underscores the need for larger, well-designed studies to confirm its translational efficacy in human wound care.
Co-Authors Achmad K. Harzif Agung Endro Nugroho Agung Endro Nugroho Andon Hestiantoro Andri Prasetiyo Anindini Winda Amalia Anindyajati Anindyajati Anita Artarini Armini Syamsidi ARTARINI, ANITA B. Atawolo, Andreas Babu, Murali Mohan Budi Wiweko Caroline G. Puspita CATUR RIANI Danang Agung Yunaidi Dayana, Hepy Debbie S. Retnoningrum Debbie S. Retroningrum DEBBIE SOEFIE RETNONINGRUM Dewi Riskha Nurmalasari Diana Nur Afifah Esti Mumpuni Esti Mumpuni Esti Mumpuni, Esti Gayatri, Anggi Gita Pratama Hapsari, Riani Harry Martha Wijaya Hartati Tuna, Hartati Heliany, Ina Henry Soelistyo Budi Henry Soelistyo Budi, Henry Soelistyo Herbert Situmorang Herbert Situmorang Huda Shalahudin Darusman Indriawati, Iin Irsan Hasan Ismaya, Wangsa T. Kaka Renaldi Kanadi Sumapradja Krisnayanti, Ni Putu Eka Kristiana, Hery Kristiana, Hery Laurentia Stephani Liana W. Susanto Lilik Sulastri Luh Putu Nurshanti, Ni Maggy T. Suhartono Maggy T. Suhartono Maggy Thenawidjaja Suhartono Marcellus Simadibrata Martha Wijaya, Harry Melva Louisa Murali Mohan Babu Murdani Abdullah Nafrialdi Nafrialdi Nailufar, Florensia Nailufar, Florensia Ni Luh Putu Nurshanti Novia Tri Astuti Novia Tri Astuti Novitasari, Putri Rachma Permanasari, Silmi Citra Rachman, Andika Raden Muharam Natadisastra Retroningrum, Debbie S. Santi Tan Saut Horas Hatoguan Nababan Setiabudy, Rahajuningsih D Shirly Kumala SILMI MARIYA Simatupang, Stefeny Theresia Sinaga, Wenny S.L. Soelistyo Budi, Henry Susanto, Liana W Suwijiyo Pramono Suwijiyo Pramono Tan, Santi Viedya Novalinda Said Wangsa T. Ismaya Wangsa Tirta Ismaya Widjaja, Nadia Winoto, Imelda L Winoto, Imelda L Yanti Lim Zaelani, Bella Fatima Dora